야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

홍수퇴적토의 식재토양 재활용 연구

조용현,조항문,현재혁,조재범,김갑수 忠南大學校 環境問題硏究所 1997 環境硏究 Vol.15 No.-

In the study , the feasibility of deposit soil in river and stream bed as a substitute for conventional plant soil was investigated through the analysis of soil characteristics and germination growth rate for 75days. Proper mix between samples from different places was compared to optimize the germination and growth rate of plant in the ratio of 2 : 1 and 3 : 1 (sand : deposit). From the results, it could be concluded that the deposit mix 3 : 1 showed most favorable germination and growth conditions for pancy and the deposit containing enough amount of silt and clay components showed most favorable conditions for marigold. Consequently, the feasibility of deposits as a substitutional plant soil was evaluated to be high.

양전자방출단층촬영을 이용한 초점주의와 작동기억의 뇌 활성화 양상 비교

김재진,조상수,김명선,손정우,이재성,이동수,이명철,권준수 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.2

연구목적: 단순 초점주의 과제와 보다 고도의 집중을 요하는 작동기억 과제를 수행하는 동안의 뇌 활성화 양상을 비교하여, 두 인지기능 과정을 매개하는 정상적 신경회로의 특성과 차이를 알아보는 것을 목적으로 하였다. 방법: 정상인 14명을 대상으로 시각처리 대조 과제, 단순 초점주의 과제, 작동기억 과제 등 세 가지 인지과제를 주고, 과제 수행 동안 [□O]H₂O를 추적자로 한 양전자방출단층활영을 실시한 후 감산분석을 통해 초점주의와 작동기억의 신경회로 지도를 작성하여 비교분석하였다. 결과: 초점주의 동안 활성화되는 부위는 좌측으로 편측화되고 산발적으로 분포하는 양상이었고, 특히 전대상이랑과 운동영역을 포함한 전두엽, 일차 및 이차 시각피질 등의 활성화가 특징적이었다. 작동기억 동안의 뇌 활성화 역시 산발적 분포와 좌측 편측화 양상이 관찰되었으나, 시각피질보다는 전두엽의 활성화가 우세하였고, 특히 우측 전대상이랑의 현저한 활성화가 특징적이었다. 결론: 초점주의와 작동기억은 개념적으로 공통점과 차이점을 내포하고 있는 것처럼 매개 신경회로에서도 공통 혹은 특이한 영역을 각각 가지며, 전대상이랑의 역할이 두 기능에 공통적으로 중요하고, 이차 시각피질과 전전두피질이 두 기능 각각에 더 중요하게 작용하는 것 같다. Objectives:This study was undertaken to identify neural substrates for simple focused attention and more highly-focused working memory i normal people and investigate their characteristics and differences. Method: Fourteen normal subjects were studied with [□O]H₂O positron emission tomography during a visual processing baseline task, simple focused attention task and working memory task. Results were analyzed with the subtraction analysis to map the neural correlates of focused attention and working memory. Results: Activated areas during focused attention tended to be lateralized to the left and scattered over various regions including the anterior cingulate, motor area, and primary and secondary visual cortices. While the areas activated during working memory also show the left lateralization and scattered distribution, activation prevailed more in the frontal lobe than in the visual cortex, and was particularly remarkable in the right anterior cingulate. Conclusions: Focused attention and working memory do not have only conceptually commonalities and differences but also have common and specific areas in their neural substrates. The anterior cingulate may commonly play an important role in both cognitive functions, whereas secondary visual cortex and prefrontal cortex seem to be predominantly implicated in each function, respectively.

볼텍스 크러셔를 이용한 순환골재 생산기술의 개발에 관한 연구

정재동,조현대,김보수 대구대학교 특수교육재활과학연구소 2010 産業技術硏究 Vol.21 No.1

To assess the performance of the vortex crusher equipment developed for this study, the results of comparative tests for physical features of the recycled aggregate in production at present and that produced passing through this development device showed the improvement of removal efficiency of cement paste by 4.5%, and the recycled aggregate output suitable for the particle size standard for road work by Ministry of Land Transportation and Maritime Affairs by 80%, absolute dryness density from 2.25g/cm3 to 2.34g/cm3, and wear reduction amount from 32% to 22%, and stability from 10% to 3%, result ratio of particle shape decision by 7% compared to existing one.

Original Articles : Clinical significance of occult hepatitis B virus infection in chronic hepatitis C patients

( Jae Young Jang ),( Soung Won Jeong ),( Sung Ran Cheon1 ),( Sae Hwan Lee1 ),( Sang Gyune Kim ),( Young Koog Cheon ),( Young Seok Kim1 ),( Young Deok Cho1 ),( Hong Soo Kim ),( So Young Jin ),( Yun Soo 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.3

Background/Aims: We investigated the frequency of occult hepatitis B virus (HBV) infection in anti-hepatitis C virus (HCV)-positive individuals and the effects of occult HBV infection on the severity of liver disease. Methods: Seventy-one hepatitis B virus surface-antigen (HBsAg)-negative patients were divided according to their HBV serological status into groups A (anti-HBc positive, anti-HBs negative; n=18), B (anti-HBc positive, anti-HBs positive; n=34), and C (anti-HBc negative, anti-HBs positive/negative; n=19), and by anti-HCV positivity (anti-HCV positive; n=32 vs. anti-HCV negative; n=39). Liver biopsy samples were taken, and HBV DNA was quantified by real-time PCR. Results: Intrahepatic HBV DNA was detected in 32.4% (23/71) of the entire cohort, and HBV DNA levels were invariably low in the different groups. Occult HBV infection was detected more frequently in the anti-HBc-positive patients. Intrahepatic HBV DNA was detected in 28.1% (9/32) of the anti-HCV-positive and 35.9% (14/39) of the anti-HCV-negative subjects. The HCV genotype did not affect the detection rate of intrahepatic HBV DNA. In anti-HCV-positive cases, occult HBV infection did not affect liver disease severity. Conclusions: Low levels of intrahepatic HBV DNA were detected frequently in both HBsAg-negative and anti-HCV-positive cases. However, the frequency of occult HBV infection was not affected by the presence of hepatitis C, and occult HBV infection did not have a significant effect on the disease severity of hepatitis C. (Korean J Hepatol 2011;17:206-212)

전방 또는 전측방 흉수 종양 수술에서 후측방도달법

조경석,박춘근,성재훈,허필우,박춘근,백민우,김달수,강준기 대한신경외과학회 1997 Journal of Korean neurosurgical society Vol.26 No.5

대합(Meretrix lusoria Ro¨ding)의 간췌장에 기생하는 Rickettsia-like organisms 에 대한 연구

조미영,박수일,송재희,양원석 한국어병학회 2001 한국어병학회지 Vol.14 No.3

대합, Meretrix lusoria의 폐사 원인을 조사하기 위해 1999년 2월부터 12월까지 전북지역의 대합을 채취하여 병리조직학적 검사를 실시하였다. 조직학적 검사결과 대합의 아가미와 간췌장의 상피세포에서 구형 또는 타원형의 호염기성 봉입체가 관찰되었다. 감염 조질은 상피세포의 비대 또는 세포용해 현상과 심한 경우 소화맹낭 조직이 파괴되어 있었다. 세포내 봉입체를 투과전자 현미경으로 관찰한 결과 rickettsia-like organisms(1.2∼2.0㎛ or 0.27∼0.58×1.18㎛)으로 확인되었다. 또한 주변의 괴사 조직에서 크기가 매우 작고, 세포벽을 가지고 있으며 미네랄화된 nanobacteria(146∼600×261∼625nm)가 다수 관찰되었다. nanobacteria가 감염된 조직에서는 심한 세포질의 공포화 현상이 관찰되었으며, 다수의 크리스탈성 과립도 함께 관찰되었다. The histopathological survey was performed to search for the cause of mass mortality of the hard clam Meretris lusoria in 1999. Histological section showed spherical or elongated intracellular basophilic inclusions in the gill filaments and digestive diverticula of the moribund clams. The hypertrophy and lysis of epithelial cells and multifocal necrosis were observed in affected tissues. TEM demonctrated two different rickettsia-like organisms; the one was large, coccoidal (1.2~2.0㎛ in diamenter) organisms observed in the nera nuclei and the other was polymorphic, rod-shaped (0.27~0.58×1.18㎛)organisms tightly packed within cytoplasmic vacuoles or scattered throughout the cytoplasms. Moreover, the smallest, mineralized, cell walled nanobacterias (146~600×261~625nm)were found in various tissues of the moribund hard clams. In nanobacteria-infected tissues cytoplasmic vacuolization and numerous crystalline deposits were found.

상아질에 대한 자가 산부식 접착제의 전단결합강도와 SEM 분석 비교

조영곤,노기선,김수미,이영곤,정진호,기영재 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.3

The purpose of this study was to compare shear bond strength and interfacial pattern of composite bonded to dentin using self-etching adhesive systems. Sixty extracted human molars with exposed occlusal dentin were divided into four groups and bonded with four adhesives and composites: Single Bond/Filtek Z 250(SB), Tyrian SPE-One-Step Plus/Aelitefil(TY), Prompt L-Lpop/Filtek Z 250(LP), and one-Up Bond F/Palfique Toughwell(OU). The results of this study were as follows; 1. Shear bond strength for OU was significantly lowet than that of other groups(p<0.05). No significant difference was founded among SB, TY, and LP. 2. Failure modes to dentin showed adhesive and mixed for SB, TY, and LP, but them for OUT showed adhesive in all spceimens. 3. Dentin-resin interface showed close adaptation for SB, TY, and LP, but it showed gap for OU. 4. The hybrid layers for TY, LP, OU were thinner than that of SB. Adhesive layers were observed between composite and hybrid layer, which were 5 ㎛ thick for TY and 10 ㎛ thick for OU.

복잡한 영상신호에서 움직이는 물체 자동 감지, 획득 및 추적에 관한 연구

조재수 한국기술교육대학교 2003 論文集 Vol.10 No.1

An effective method is proposed for detecting, acquisition and tracking of a moving object using a disturbance map method in complex image sequences. A significant moving object is detected and tracked within the field of view by computing a modified disturbance map method between an input image and a temporal average image. This method is very efficient in the surveillance application of digital CCTV and an automatic tracking camera. We also propose an adaptive sizing of tracking window considering of moving object changes. Experimental results using various real image sequences confirmed that the proposed method can effectively detect and track a significant moving object in complex image sequences.

주의력결핍과잉행동장애와 Alpha-1C-Adrenergic 수용체 유전자와의 연관성에 대한 연구

조수철,김재원,김붕년,황준원,박미라,김순애,조대연,유희정,정운선,손정우,박태원 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.1

Objectives : Neurobiological and pharmacological research has suggested that the dysregulation of the central noradrenergic systems might be involved in the pathophysiology of ADHD. The aim of this study was to examine the association of the alpha-1C-adrenergic receptor gene (ADRA1C) with ADHD in Korean subjects. Methods : In a case-control study, we assessed 186 DSM-IV ADHD probands and 150 normal controls. One hundred and eight trios were studied in a family-based association analysis. Psychiatric diagnoses were derived through structured diagnostic interviews. For the clinical evaluation of the ADHD subjects, the Child Behavior Checklist (CBCL), the ADHD Rating Scale-IV (ARS) and the Junior Temperament and Character Inventory (JTCI) were administered. A computerized continuous performance test (CPT) was used to measure the inattention and impulsivity of the ADHD children. Results : There were no significant differences in the genotype or allele frequencies of the ADRA1C PstI polymorphism between the ADHD and control group (p>0.05). The transmission disequilibrium test (TDT) analysis observed no evidence for biased transmission of any of the alleles of the PstI polymorphism. There were no significant differences in the CPT or JTCI profiles between those ADHD subjects with the CC genotype and those with the other (CT+TT) genotypes at the PstI polymorphism. Conclusion : The results of this study do not support the ADRA1C as a major genetic susceptibility factor in ADHD.