노인 인구에서 신경인지기능저하와 혈청 지질농도와의 상관성

유영선,최석주,정성수,김지은,윤성욱,전동욱,백준형,박성우,이정구,추일한,김영훈 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.6

Objectives : In this study, the authors evaluated the correlation between eurocognitive impairments and serum lipids levels among Korean elderly over the age of 65. Methods : A total of 609 elderly individuals participated in this study. Screening for cognitive impairments were carried out using the Mini-Mental Status Examination-Korean version (MMSE-KC). There were 197 subjects above 1.5SD Of MMSE- KC and they were evaluated using the Korean versions of the Consortium to Establish a Registry for Alzheimer's Disease (AD) (CERAD-KC) and Geriatric Depression Scale (GDS-K). Results : There was a correlation between old age/low levels of education and AD (p<0.05, P<0.01). There was an inverse correlation between the serum level of total cholesterol and the word list recognition test scores. The serum levels of LDL cholesterol were inversely correlated with the scores on the constructional praxis test, word list recall test and word list recognition test. Inverse correlations between the serum level of triglyceride and scores on the word list recall test and word list recognition test were also observed. Conclusion : There were inverse correlations between the serum levels of lipids and language/memory function in subjects with AD.

CD34+ 조혈 모세포 이식 2례

김정아,정현식,김원석,윤성수,이홍기,박찬형,박성규,김동욱,이종욱,한치화,민우성,김춘추,김동집 대한조혈모세포이식학회 1996 대한조혈모세포이식학회지 Vol.1 No.1

Background: In most solid tumors, the CD34 antigen has not been detected, so positive selection of CD34+ cells may reduce tumor cell contamination and the CD34+ cells are capable of reconstituting hematopoiesis. We tried CD34+ cell transplantation in two patients. Method: CD34+ cells from chemotherapy + G-CSF mobilized PBPCs or bone marrow were positively selected with an avidin-biotin immunoadsorption column (CEPRATE SC system). Case 1. One course of chemotherapy using cyclophosphamide(200㎎/㎡) and etoposide (4.2g/㎡), combined with G-CSF(5㎍/㎏) S.C. was used in a relapsed lymphoma patient. This patient responded to the induction chemotherapy. CD34+ cells from harvested bone marrow were selected by the CellPro immunoadsorption column. The total number of mononuclear cells loaded onto the CellPro was 2.4×10^(8)/㎏, with 1.1% CD34+ cells. After column separation, the total number of positively selected cells was 5.16×10^(6)/㎏. The number of CFU-GM was 76.8×10⁴/㎏. This patient was treated with melphalan (140㎎/㎡) and TBI (1200cGy) and the positively selected CD34+ cells were infused. The time to neutrophil recovery greater than 0.5×10^(9)/L was 19 days and the time to platelet recovery greater than 50×10^(9)/L was 21 days. Case 2. Two courses of mobilizing chemotherapy were given 4 weeks apart using taxol(210㎎/m2) and adriamycin(60㎎/m2), combined with G-CSF(5㎍/㎏) S.C. in a breast cancer patients with 7 axillary node metastasis. CD34+ cells from each single leukapheresis product were selected by the CellPro immunoadsorption column. In the first collection, the total number of nucleated cells was 4.4×10^(8)/kg, with 0.42% CD34+ cells. In the second collection, the total number of nucleated cell was 2.8× 10^(8)/㎏ with 0.43% CD34+ cells. After colum separation, the total numbers of collected cells were 4.0×106/kg and 4.8×10^(6)/kg, the total number of CD34+ cells were 1.2×10^(6)/㎏ and 0.82×10^(6)/㎏. Colonogenic assays of positively selected CD34+ cells gave rise to myeloid erythroid, and multilineage colonies, with a median of 190 CFU-GM, 190 BFU-E, and 164 CFU-GEMM per 1×10³ adsorbed cells, respectively. High-dose chemotherapy with cumulative doses of 40mg/㎡ mitoxantrone, 750mg/㎡ thioptepa, and 1000mg/㎡ carboplatin was administered. Positively selected CD34+ cells were rapidly infused 24 hours after the end of high-dose chemotherapy. The time to neutrophil recovery greater than 0.5×10^(9)/L was 16 days and the time to platelet recovery greater than 50×10^(9)/L was 20 days.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

근관장 측정시 구내 디지털 방사선 시스템인 Digora System의 정확도에 관한 연구

한상욱,홍찬의,조용범 大韓齒科保存學會 1997 Restorative Dentistry & Endodontics Vol.22 No.1

플라즈마 반응기에서 전극의 배열에 따른 탈질반응의 변화

한영욱,이상권 漢陽大學校 環境科學硏究所 2003 環境科學論文集 Vol.24 No.-

플라즈마를 이용한 배연탈황/탈질 동시처리에 관한 많은 연구들이 전기에너지나 첨가제가 SO_2/NOX의 제거효율에 미치는 영향을 살펴보기 위하여 수행되어 왔다. 이러한 연구결과들에 의하면, 플라즈마가 SO_2의 제거에는 커다란 영향을 주지 못하지만, NOX의 제거에는 인가되는 전기에너지에 따라 탈질율이 변화하는 것으로 보고되고 있다. 따라서 본 연구에서는 반응기에 최적의 에너지를 인가하는 방법을 조사하기 위하여 전극 배열에 따른 탈질율의 변화를 확인하기 위한 실험을 수행하였고, 상세한 실험결과는 본문 중에 제시되었다. 본 실험결과, 플라스마를 이용한 배연탈황/탈질의 효율적인 동시처리를 위해서는 방전극의 구조 및 그 영향에 대한 연구, 특히 에너지 소모량을 최소화하는 방전극의 최적화에 대한 연구의 필요성을 암시하고 있다. Many experimental studies on the combined removal of SO_2 and NOX using plasma for the flue gas desulfurization and denitrification have been performed in order to investigate the effect of electric power or additives on the SO_2/NOX removal. The results showed the plasma was not effective on the removal of SO_2, but the change of NOX removal rate by the electric power has been observed. Therefore, this study has been performed to examine the optimized electric power. The effect of arrangement of electrode on th electricity density has been examined to observe the transfer of electric energy, and then the effect of electricity density on the NOX removal has been experimentally observed. The experimental results were discussed in this paper. The results obtained from the experiments suggested the necessity of further study on the structure of discharging electrode and its effect, and the development of the optimized electrode to minimize the energy consumption.

Angus, Hereford, Charolais種과 그 交雜種의 生時體重에 미치는 環境要因의 影響

韓成郁 충남대학교 농업과학연구소 1977 農業技術硏究報告 Vol.4 No.2

This study was conducted from 1974 to 1977 at Chedong Animal Farm in Che-Ju to determine the effect of sex of calves, birth year and season, breeds and crossing methods on the birth weight of cattle. A total of 1020 calves from Angus, Charolais, Hereford breeds and their crossbred were used for the study and least square methods was applied to analysis the data. Birth weight of male calves was 1kg heavier than that of female. Highly significant differences were obtained in the effects of birthyear on the birth weight. i.e. the cattle born in 1976 and 1977 was 0.9 and 0.2kg heavier in birth weight than those born in 1975. The cattle born in 1974, when the farm was established, was 1.7kg lighter than those in 1975. The calves born in the spring and the summer was 0.6 and 0.3kg heavier in birth weight than those born in the winter. The calves born in the fall was 0.9kg lighter than the calves born in the winter. In birth weight, Charolais breed were 0.4kg heavier than those from Hereford breed. Angus breed were 1.1kg lighter than Hereford. The crossbred between Charolais and Hereford breed were 1.5kg heavier than the Hereford. The birth weight of calves from Angus and Hereford crossbred and Angus and Charolais crossbred were 0.6 and 0.4kg lighter, than Hereford breed respectively.

미드의 白我理論과 社會科敎育

韓相旭 순천대학교 사회과학연구소 1989 社會科學硏究 Vol.2 No.-

The goal of social studies is to develop the democratic citizenship of the students. And that democratic citizenship means the self of the person in a democracy. So, the goal of social studies is to make students take the role of the generatized other. According to Mead, the self arises from the social organization to which it belongs, while the social organization reflects the self. The self is not initially there, at birth, but arises in the process of social experience and activity, that is, develops in the given individual as a result of his relations to that process as a whole and to other individuals within that process. A person is a personality because he belongs to a community, because he takes over the institutions of that community into his own conduct. He takes its language as a medium by which he gets his personality, and then through a process of taking the different roles that all the others furnish he comes to get the attitude of the members of the community. He continually takes the attitudes of the others about him, especially the roles of those who in some sense control him and on whom he depends. Such Mead's Theory of self implies very important points to the social studies education. First, the teacher should make the students know that he really expects the students to be democratic and moral beings, because the students take the attitude of the teacher on whom they depend. Second, the students should continually be asked to put themselves in the place of the generalized other, because the only way to learn to take the attitude of the other is to engage in taking that of the other. Only this approach in social studies education will affect the citizenship and the self of the students.

한국재래오골계의 난구성분 및 난질의 유전모수추정

한성욱 제주대학교 농과대학 제주도축산문제연구소 1991 畜産論叢 Vol.6 No.1

This study was conducted to estimate heritabilities and genetic correlation on egg compositions and egg qualities in Korean Native Ogol fowl. The data analysis were a total of 58,320 eggs in 450 pul-lets produced from 150 dams and 20 sires of Korean Native Ogol fowl raised at Chungnam National University from June 18,1987 to April 6,1989. The results as obtained are summarized as follows: 1. The heritability estimates of egg compositions based on the variance of sires, dams and combine com-ponents were 0.620~0.723, 0.206~0.300 and 0.413~-0.511 for albumen weight : 0.439~0.737, 0.484~0.544 and 0.492~0.615 for yolk weight : 0.172~0.187, 0.412~0.642 and 0.390~0.503 for Haught units. 2. The heritabilities estimates of egg qualities based on the variance of sires, dams and combined com-ponents were 0.202~0.279, 0.557-0.819 and 0.428-0.508 for shell thickness : 0.202-0.394, 0.119-0.678 and 0.256~0.440 for albumen height : 0.108~0.443, 0.237~0.698 and 0.254-0.399 for Haught units. 3. The genetic and phenotypic correlations of egg compositions were as follows ; The coefficients be-tween albumen weight and yolk weight were 0.089-0.564 and 0.084-0.235 ; between albumen weight and shell weight were 0.396~0.925 and 0.225~0.544 ; between yolk weight and shell weight were 0.220~0.357 and 0.098-0.358, respectively. 4. The genetic and phenotypic correlation as follows ; between shell thickness and albumen height were 0.082-0.356 and -0.163-0.060 ; between shell thickness and Haught units were -0.076~0.167 and -0.185-0.010 ; between albumen height and Haught units were 0.338-0.604 and 0.154~0.285, respectively. 5. The genetic correlation of egg compositions and egg qualities were as follows: between albumen weight and shell thickness, albumen height, Haught units were -0.380~-0.002, 0.239-0.387, and -0.279~-0.127; between yolk weight and shell thickness, albumen height, Haught units were -0,049~0.133 and -0.196~-0.136; between shell weight and shell thickness, -0.294~-0.133, albumen height, Haught units were 0.127~0.476, 0.140~0.273 and 0.038~0.233, respectively.

Dioxin류의 반응에 대한 분자궤도함수론적 연구 : dibenzo-p-dioxin, 2,7-dichlorodibenzo-p-dioxin, dibenzofuran, 2,8-dichlorodibenzofuran 중심으로

한성욱,이길준,김복조 경운대학교 산업기술연구소 2001 産業技術硏究論文誌 Vol.3 No.2(B)

Molecular orbital studies for dibenzo-p-dioxin, 2,7-dichlorodibenzo-p-dioxin, dibenzofuran and 2,8-dichlorodibenzofuran were carried out by semiempirical PM3 method. Reaction sites for nucleophilic, electrophilic and radical reaction of dioxins were predicted and discussed by MO studies. The values of approximated superdelocalizability were 0.7802, 0.2686, 0.3104, 0.1982 for the above dioxins, respectively. And reported rate constant for the reaction of dioxins with OH radical (Eitzer et. al.. Environ, Sci. Technol. 1989, 23, 1389) was well correlated with approximated superdelocalizability.

이중관 기포탑에서의 비뉴튼류의 기-액간 물질이동

한승환,김상렬,최재욱,최일곤 東亞大學校 1991 東亞論叢 Vol.28 No.1

The effect of draught tube dimension, properties of CMC aqueous solution and gas velocity on the gas holdup, ??, and the volumetric liquidphase masstransfer coefficient, ??, in a bubble column with draught tube were measured in highly viscous-pseudo plastic carboxymethylcellulose aqueous solution. The results were as follows : 1. ?? and ?? increase with increasing gas velocity and decrease with increasing concentration of CMC aqueous solution. 2. ?? and ?? increase with being enlarged diameter ratio of draught tube but specially ?? decreases to some degree in the CMC concentration of 0.05∼0.7wt%. 3. Correlations among various parameters having an influence on ?? and ?? were expressed by Eq. (16) and Eq. (17), respectively. ??