농촌 자활사업참여자의 음주 문제 개입프로그램 개발: 동기강화상담의 적용

이종례(Jong Rea Lee),장수미(Soo Mi Jang),허성희(Seong Hui Heo) 한국지역사회복지학회 2022 한국지역사회복지학 Vol.- No.83

본 연구의 목적은 동기강화상담(Motivational Interviewing: MI) 모델을 적용하여 농촌 자활사업참여자의 음주 문제 개입프로그램을 개발하는 것이다. 개입연구(Intervention Research: IR)의 절차에 따라 문헌고찰, 실무자 인터뷰를 시행한 후 농촌 자활사업참여자의 음주문제 양상을 파악하고, 동기강화상담의 원리와 전략에 기반하여 1차 프로그램을 구성하였다. 전문가 자문을 통해 수정 보완 후 2차 프로그램을 도출하였고, 음주 문제를 가진 농촌 자활사업참여자를 실험집단(n=10)과 통제집단(n=10)으로 무작위 배치한 후, 실험집단에 동기강화상담 기반 음주 문제 개입프로그램을 실시하였다. 사전‧사후‧추후 조사를 통해 개입프로그램의 효과성을 평가한 결과, 실험집단의 음주 지식, 단주 자기효능감, 변화 동기, 음주 문제, 자활 성과의 사전‧사후 점수에서 유의미한 변화가 발생하였고, 음주 문제를 제외한 모든 변인에서 사전‧추후 점수의 유의미한 변화가 나타났다. 음주 문제의 경우 사전‧추후, 사후‧추후 모두 유의미한 변화가 발생하지 않아 효과성이 유지되지 않음을 확인하였다. 이후 현장 실험 결과에 대한 피드백을 반영하여 최종(3차) 프로그램을 개발하였다. 결론에서는 주요 연구 결과를 바탕으로 논의하고, 자활 현장을 중심으로 사회복지 실천 및 정책에의 함의를 제시하였다. The purpose of this study is to develop an intervention program for the drinking problem of participants in rural self-sufficiency center by applying the Motivational Interviewing(MI) model. According to the stages of Intervention Research(IR), the aspects of drinking problems of rural self-sufficiency participants was identified through literature review and interviews with practitioners, and the 1st program was constructed based on the principles and strategies of MI. After revising with experts advice, a 2nd program was derived, and rural self-sufficiency participants with drinking problems into an experimental group(n=10) and a control group(n=10) by random assignment, MI was conducted only in the experimental group. As a result of the program, significant changes occurred in the pre and post scores of the experimental group’s drinking knowledge, abstinence self-efficacy, change motive, drinking problem, and self-sufficiency outcomes, and significant changes in pre and 6 weeks later scores were found in all variables except for drinking problems. The drinking problem was not significant in pre and 6 weeks later, post and 6 weeks later, it could be seen that the effectiveness was not maintained. The 3rd(final) program was developed by evaluating the effectiveness of the programs, and reflecting feedbacks from field experiment. In conclusion, the implications for social welfare practices and policies were presented, focusing on the field of self-sufficiency.

개에서 발생한 기관 허탈의 진단과 관리

이새미,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

A 11-year-old Yorkshire terrier anesthetized for computed tomography. The dog showed cyanosis and syncope during postanesthetic recovery, therefore drug administrated parenterally. Goose-honking was noticed after full recovery. As a result of survey radiography and fluoroscopy, grade 4 tracheal collapse was diagnosed. Prescription for the dog was oral administration of hydrocodone 0.22 mg/kg. theophylline 20 mg/kg, prednisone 0.5 mg/kg, amoxicillin 22 mg/kg and chlorpheniramine 2 mg/kg twice a day for 3 days. A 10-year-old Pomeranian was diagnosed as grade 2 traceal collapse at the local animal hospital 2 years before being referred to the veterinary teaching hospital of Chungnam National University. On physical examination, goose-honking, coughing and intermittent open-mouth breathing. Tracheal narrowing was observed on survey einradiography and fluoroscopy. Oral administration of theophylline 13 mg/kg, enrofloxacin 5 mg/kg, chlropheniramine 0.5 mg/kg twice a day was prescribed for 2 weeks.

개에서 발생한 양파 섭취에 의한 하인즈 소체 용혈성 빈혈 증례

이미선,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

A 10 month-old Yorkshire Terrier was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with the history of lethargy, bile pigment in urine and anorexia. Blood smear showed Heinz body, polychromatocytosis, schistocytosis, anisocytosis, which were the results from the oxidative injury. Hematology demonstrated a moderate anemia(PCV 22.4%, reference rage 35-55%), which was regeneration based on the degree of RPI (4.03, reference rage > 1). Serum biochemistry demonstrated mild elevation in total bilrubin, and mild decrease in total protein and albumin concentration. A diagnosis of Heinz body hemolytic anemia secondary to onion ingestion was made and treated with fluid therapy, oxygen and antioxidant drugs. The dog recovered without any complication.

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

모세관 전기영동법을 이용한 1,2,4-트리메틸벤젠 대사체의 분석

강종성,홍정희,임정미,이용문,장재연 충남대학교 약학대학 의약품개발연구소 1999 藥學論文集 Vol.15 No.-

방향족 탄화수소인 tnmethylbenzene (TMB)은 그 사용량이 늘어갈 뿐 아니라 직업적으로 폭로되는 양도 증가하고 있으므로 생물학적 모니터링 및 흡수, 대사, 배설에 관한 연구가 중요시되고 있다. 일반적으로 TMB는 간의 산화효소에 의해 하나의 메틸기가 산화되고 이것은 glycine과 포합되어 배설되는 것으로알려져 있다. 본 연구에서는 1,2,4-TMB의 대사체를 합성하고, 모세관의 전기영동법으로 분석할 수 있는 방법을 개발하였다. 모세관 전기영동법으로 흰쥐의 뇨 중에서 1,2,4-TMB의 대사체인 3,4, 2,4, 2,5-dimethylbenzoic acid 및 3,4 2,4 2,5-dimethylhippuric acid를 분석하기 위하여 내경 75㎛, 총길이 35cm (검출기까지 29cm)인 용융실리카 모세관을 15℃로 유지하면서 양단에 10kV의 전압을 걸어주고, 전해질로는 15mM β-CD, 3% 2-프로판올을 포함하는 01m 인산완충액 (pH 7)을 사용하였으며, 검출신호는 UV 210nm와 254nm에서 동시에 모니터링하였다. 뇨 시료의 분석 결과 배설된 1,2,4-TMB의 대사체의 상대량은 3,4-이성질체가 56.&%, 2,4-이성질체가 30.5%, 2,5-이성질체가 12.8%였다. 이 방법은 노동자의 뇨 분석에도 적용될 수 있을 것으로 생각된다. The metabolites of 1,2,4-trimethylbenzene (TMB) were synthesized and determined by capillary electrophoresis (CE). The optimum conditions of CE for the separation and determination of 3,4-, 2,4-, 2,5-dimethylbenzoic acid and 3,4-, 2,4-, 2,5-dimethylhippuric acid from the rat wine were as following: the fused silica capillary(75μm i.d. X 36 cm length, 29 cm to detector) was used and kept at 15℃ The applied voltage was 10kV and compounds were detected at UV 210 nm and 254 nm. The running electrolyte was 0.1 M phosphate buffer (pH 7) contalI1ing 15 mM of β -CD and 3% of 2-propanol. The relative amount of the metabolite of 1,2.4-TMB in the rat urine was 56.7% of 3,4-isomer, 30.5% of 2,4-lsomer and 12.8% of 2,5-isomer. This method can be applied to the analysis of TMB-metabolites in human wine.

모세관 전기영동법을 이용한 베타차단제 광학이성질체의 분석

임환미,린팜두안,강종성 충남대학교 약학대학 의약품개발연구소 2000 藥學論文集 Vol.16 No.-

The effects of type of chiral selectors, pH and concentration of electrolyte on the resolution of the enantiomers of β-blockers by capillary electrophoresis were examined and the analysis of β-blocker enantiomer was attempted using various chiral selectors, such as carboxymethyl-, methyl-, succinyl, hydroxypropyl and dimethyl-β-cyclodextrin. Among the used chiral selectors, carboxymethyl-β-cyclodextrin (CM-β-CD) was the best for the separation of β-blockers. The optimum separation of the enantiomers of β-blocker was achieved on fused silica capillary (75 um i.d.×47 cm, 40 cm to detector) with phosphate buffer (pH 6, 70 mM) containing 10 mM of CM-β-CD as electrolyte at 10 KV running voltage. Injection was hydrodynamically for 3 psi×s and detection was carried out at UV 210nm.

정상인에서 전기 및 자기 자극을 이용한 설 근육의 전기생리학적 평가

조은미,류종현,안성환,조경원,임건한,김진호,김후원 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.1

Background: Abnormality of lingual muscles is clinically common. But its exact clinical assessment is quite difficult. Evaluation of motor power of the lingual muscles and their neural pathway is limited because of anatomical inaccessibility and individual variation of subjective symptoms. Transcranial magnetic stimulation (TMS) of the human motor cortex is a non-invasive tool to assess the functional integrity of the fast conducting central motor pathways and electrical stimulation of lingual nerve is a conventional method of peripheral nerve conduction. Therefore both study will be helpful to understanding of pathophysiology of lingual abnormality. Until now there is no such report in Korea. This study was conducted to acquire the easier method and normal control values of Korean subjects. Method: We recorded the motor responses from the lingual muscles of 32 healthy subjects (22 men, 10 women) by focal cortical TMS with a circular coil. Motor potentials were recorded by means of surface electrodes applied on the both side of the tongue, following TMS several centimeters lateral from the vertex and parietooccipital cortex and peripheral electrical stimulation of the 12th cranial nerve at the lateral 1/3 point of the line between the midline and angle of mandible. Results: During moderate motor activation, majority of maximal motor response were obtained 4-6cm lateral to the vertex with similar latencies. And the responses from magnetic stimulation of the intracranial segment of hypoglossal nerve were discarded because of difficulty to obtain and unsatisfactory reproducibility. The latency of motor evoked potentials in right cortical stimulation was 10.08 ± 1.17 msec and in left stimulation 10.04 ± 1.32 msec. The amplitudes in right 2.15 ± 1.02, left 2.09 ± 1.11 mV. The latencies electric hypoglossal nerve stimulation were 2.42 ± 0.34 in right, 2.49 ± 0.35 msec in left side. The amplitudes were 2.90 ± 2.37 in right, 2.43 ± 1.86 mV in left side. Central conduction times as calculated by subtracting the response latencies obtained by magnetic and electric stimulation are right 7.65 ± 1.19, left 7.55 ± 1.35 msec. There was no significant difference between man and woman, Conclusion: The method may be efficient, noninvasive, painless, and easy reproduced. With more extensive application to various neurological disorders, it comes close to being an ideal clinical conduction study technique for this cranial nerve.

조혈모세포이식 환자에서 침습성 진균 감염에 대한 이트라코나졸 액과 플루코나졸 시럽의 예방 효과 : 전향적, 무작위, 비교 임상시험

최수미,이동건,최정현,박선희,엄기성,김유진,김희제,민창기,유진홍,김동욱,이종욱,민우성,신완식,김춘추 대한감염학회 2005 감염과 화학요법 Vol.37 No.2

목적 : 조혈모세포이식 환자에서 호중구 감소 기간 동안 이트라코나졸 액(ITZS)과 플루코나졸 시럽(FCZS)의 진균 감염에 대한 예방 효과를 전향적으로 비교해 보고자 하였다. 재료 및 방법 : 2001년 8월부터 2002년 6월까지 가톨릭 조혈모세포이식센터에 입원하여 동종 조혈모세포이식을 받은 만 18세 이상의 환자들을 각각 ITZS와 FCZS군으로 무작위 배정하여 침습성 진균 감염 발생과 약제 관련 부작용을 전향적으로 조사하였다. 결과 : ITZS군에 40명, FCZS군에 38명이 배정되었고, FCZS군 환자의 평균 나이가 더 많았다. 시험 약제 평균투여기간은 ITZS군 16.4일, FCZS군 21.9일로 ITZS군이 더 짧았다. 이는 ITZS군에서 소화기 부작용으로 인한 약제 중단이 더 많았기 때문으로 보인다. 시험 약제 투여 후 총 빌리루빈 수치의 유의한 증가가 관찰되었으나, 약제 관련 부작용은 모든 환자에서 가역적이었다. 호중구감소 기간동안 표재성 진균 감염은 두 군에서 모두 발생하지 않았고, 침습성 진균 감염은 ITZS군 5명(12.5%), FCZS군 8명(21.1%)으로 FCZS군에서 많았으나, 통계학적으로 유의하지 않았고, 사망률에도 유의한 차이는 없었다. 결론 : 침습성 진균 감염에 대한 이트라코나졸 액과플루코라졸 시럽의 예방 효과에 유의한 차이는 없었으나, 앞으로 더 많은 환자를 대상으로 잘 짝지어진 대조군 연구가 필요할 것으로 보인다. 부작용 중 간독성과 관련하여 이식시 투여되는 여러 약제들과의 상호작용에 대한 연구도 필요할 것이다. Background : Though fluconazole is widely used for antifungal prophylaxis, it is ineffective against mould infections including Aspergillus species. Itraconazole has a broader spectrum than fluconazole but the capsule form shows erratic bioavailability in neutropenic patients. In this study, we compared itraconazole oral solution (ITZS) with fluconazole syrup (FCZS) for the prevention of invasive fungal infection (IFI) in allogeneic hematopoietic stem cell transplant recipients. Materials and Methods : Adults receiving allogeneic hematopoietic stem cell transplantation (HSCT) from september 2001 to June 2002, were randomly allocated to either the ITZS group or the FCZS group. We prospectively evaluated the safety and efficacy of each drug. Results : Out of 78 patients (40 patients in the ITZS group and 38 patients in the FCZS group) who were eligible for this study, 37 patients completed the course of prophylaxis without any evidence of IFI. The mean duration of prophylaxis was 16.4 days for the ITZS group and 21.9 days for the FCZS group (P<0.006). Drug-related adverse events occurred in 28 patients (70.0%) and 19 patients (50.0%) in the ITZS group and the FCZS group, respectively. Common adverse events of ITZS were nausea, vomiting, and diarrhea. Drug-related reversible hepatotoxicity occurred in 4 patients in the ITZS group. There was a significant elevation of total bilirubin level in the ITZS group. The incidence of suspected IFI occurred in 5 patients (12.5%) who received ITZS, compared with 8 (21.1%) who received FCZS (P=0.372). There were no proven IFIs or superficial (oral/vaginal) fungal infections in both groups. Overall mortality was not different between the two groups (2.5% in the ITZS group versus 5.3% in the FCZS group, P=0.610). Conclusion : ITZS and FCZS showed similar protection against IFI during pre-engraftment period. Poor tolerability due to gastrointestinal troubles of ITZS might limit its success as prophylactic therapy. Well matched controlled study with large number of patients will be required in the future.

자동화학검사용 영동시약의 평가

이성규,공선영,송선미,이수연,김종원 대한임상검사정도관리협회 1992 臨床檢査와 精度管理 Vol.22 No.2

염소 분자의 광분해 반응 : 광음향적 연구 Photoacoustic Studies

이종미,김성규,박승민 성균관대학교 기초과학연구소 1995 論文集 Vol.46 No.2

펄스형 레이저 광을 흡수하면 이원자 분자가 큰 운동에너지를 가진 원자 조각들을 만들게 된다. 조각들의 후진시 집단적인 선형 운동량은 거시적인 압력파처럼 행동하게 된다. 여기서 염소 분자의 광분해 반응에 의해서 광음향파가 생성되는 것을 설명하고자 한다. 탐사선 회절법은 빠른 광분해 반응과 그후 느린 재결합 반응에서 생긴 순간적인 광음향파를 탐지하는데 사용이 된다. 광자 한 개 뿐만 아니라 다광자의 광분해 반응시 발생하는 광음향파 신호가 관찰되었다. Photodissociation of diatomic molecules by absorption of pulsed radiation produces atomic fragments with large kinetic energy. The collective linear momenta of recoiling fragments act as a macroscopic pressure wave. We report the generation of photoacoustic waves by photodissociation of chlorine molecules. The probe beam deflection method was employed to detect the transient photoacoustic waves generated by fast photodissociation and slow recombination process thereafter. The photoacoustic signals from the multiphoton as well as the single photon dissociation were observed.