대장 및 직장암 256예에 대한 임상분석

조종기,조현진 대한대장항문학회 1994 Annals of Coloproctolgy Vol.10 No.1

개에서 응성 의양성 자웅동체의 1례

조종기,정성목,김민규,남동현,정연우,강성근,황우석,이병천 한국임상수의학회 2002 한국임상수의학회지 Vol.19 No.3

Male pseudohermaphrodites is one of abnormalities of phenotypic sex and have an XY chromosome constitution and testes, but the internal or external genitalia are to some degree those of a female. We surveyed one case which were referred in Veterinary Medical Teaching Hospital of Seoul National University. When patient was purchased, its phenotype was entirely female that have female external genitalia. However, from the age of 6 months, clitoris was gradually increased to Os clitoris, and patients showed male behavior. Critical clinical sign was trauma of protruded Os clitoris. In radiographic and ultrasonographic examination, he had normal vagina and urinary bladder. In chromosome examination, he had an XY chromosome constitution. This case was performed removal of Os clitoris and ovariohysterectomy.

Fiber Bundle U_(n)上의 特性寫像에 衣한 奇數次元球面 S^(2n-1)의 超曲面

曺鍾奇 朝鮮大學校 自然科學硏究所 1982 自然科學硏究 Vol.5 No.-

By the connected expanding of fiber bundle 〔6〕,〔7〕 and Hopf-map 〔5〕, We computed 4-dimensional homotopy group π_(4)(R_(n)), n>=6 on S^(2n-1) about characteristic map〔8〕 of canonical form as following. We have only to compute the kernel of π_(4)(R_(5)→π_(4)(R_(6)) by 〔Theorem 1〕, we formed π_(4)(R_(4) as cyclie group of 2-order that generated as the image of β_(4) by 〔theorem 2〕. If it is decided that T_(6) : S^(4)→R_(5) represents image of the kernel's generator β_(4), because the projection of T_(6) p : R_(5)→S^(4) is deformed to a map T' : S^(4)→R_(4), The formation of T_(4) is generated by unitary group in orthogonal group by presenting T' as characteristic map following to unitary group U_(2) of fiber bundle on S^(5). Consequently, we gained the result π_(4)(R_(n))=0, n>=6 by presenting that p'T'_(m+1) is represents β_(4) by theorem 3, asserting that p'T'_(m+1) is homotope with the suspension of identity map f : S^(2m-1)→S^(2m-1) by induction.

代數的 位相幾何學의 槪念에 關하여

曺鍾奇 朝鮮大學校 師範大學 1976 師大論文集 Vol.7 No.-

대수적인 위상기하학의 개념은 여러가지로 들 수 있으나 그 중 중요한 개념의 하나는 Homology이다. 여기에서는 추상적인 방법을 떠나 부동점 만으로 된 직선을 갖는 공선병환 및 해석적인 수단에 의해서 Homology를 논급한다. 정의 Ⅰ. 직선 g 위의 모든 직선이 부동점이고 항등변환 E와는 일치하지 않는 평면 상의 공선변환을 S라 한다. 정의 Ⅱ. 각점 X(χ_1, χ_2, χ_3)에 따라 한 조씩 기 Vector E_1, E_2, E_3가 정해져 있고 이때에 X를 원점으로 하여 E_1, E_2, E_3를 기 Vector로 하는 좌표계를 생각한다. 이것을 표구 (frame)라 한다. 또한 일반의 위치에 있는 4점 A_1, A_2, A_3, E로서 사영좌표 표구〔A_1A_2A_3E〕에서 A_1, A_2, A_3는 제일, 제이, 제삼, 좌표점이고 E는 단위점이다. 표구에서 점의 순서가 중요한 것이다. 평면 상의 3점 A_1, A_2, A_3가 주어져 이들의 좌표를 각각 A_1(a11, a_12, a_13), A_2(a_21, a_22, a_23), A_3(a_31, a_32, a_33)라 한다.

代數的 位相幾何學의 槪念에 關하여 : Homology를 中心으로

曺鍾奇 朝鮮大學校 師範大學 1975 師大論文集 Vol.6 No.-

射影座漂가 도入된 평면상의 共線變換中 대수적 位相幾何學의 重要한 獄念의 하나인 Homology의 變淡에 있어서, 사영평면 π가 (0,1) 一이동평면이 되기 爲한 必要充分條件은 π위에서 Desargues (0,1)一定理가 성립해아 한다는 것을 밝히고, 이로써 일반적인 사영평면상의 Homology의 성질을 논급하려 한다.

Determination of the Granulosa Cell-Specific Endothelin Receptor A Deletion on Ovarian Function

조종기 사단법인 한국동물생명공학회 2014 한국동물생명공학회지 Vol.29 No.2

Endothelin 2 (EDN2) induces follicular rupture by constricting periovulatory follicles. In this study, it wasinvestigated the mechanisms of EDN2 action on follicular rupture with respect of receptor using the conditionallygranulosa cell specific EDN2 receptor type A (ETa) KO mice (gcETaKO; ETaflox/-․Amhr2Cre). It was generated thegcETaKO mice by breeding with ETaflox/- mice after mono-alleic ETa knockout by ZP3Cre and Amhr2Cre mice. Fertility,ovulation and maturation rates of ovulated oocytes after super ovulation were investigated in the gcETaKO micecompared with wild-type mice (ETaflox/flox and ETaflox/-) as a control group. In the gcETaKO mice, normal fertility afterbreeding with male mice was shown compared with wild-type mice. And, there was no significant differences inovulation rates after super ovulation, however its maturation rates was lower than that of wild type mice. Thesefindings show that EDN2 in follicular rupture for ovulation is related with an other ETa not in granulosa cells. Furtherstudies are needed to investigate how EDN2 is acted in ovarian follicular rupture for ovulation.

개의 전염성 성병성 종양의 2례

조종기,최을수,남동현,권용삼,김정태,강성근,이병천,황우석 한국임상수의학회 2002 한국임상수의학회지 Vol.19 No.3

Transmissible venereal tumor (TVT) is a contagious, sexually transmitted tumor and, in the natural setting, affects only dogs. We surveyed two cases which were serviced in veterinary medical teaching hospital of Seoul National University. Through this report we studied the method for treatment of TVT by chemotherapy and surgical resection. In treatment of TVT, surgical resection is not considered an effective method, but chemotherapy and radiation. In these two cases, chemotherapy was very effective and in the second case, there was no effect of surgical method. For treatment of TVT, chemotherapy was very effective, but surgical resection was not recommended.

Identification of abnormal gene expression in bovine transgenic somatic cell nuclear transfer embryos

조종기,Sungkeun Kang,이병천 대한수의학회 2014 Journal of Veterinary Science Vol.15 No.2

This study was conducted to investigate the expression ofthree genes related to early embryonic development in bovinetransgenic cloned embryos. To accomplish this, developmentof bovine transgenic somatic cell nuclear transfer (SCNT)embryos was compared with non-transgenic embryos. Next,mRNA transcription of three specific genes (DNMT1, Hsp70.1, and Mash2) related to early embryo development intransgenic SCNT embryos was compared between transgenicand non-transgenic SCNTs, parthenogenetic embryos, and invitro fertilization (IVF) embryos. Transgenic SCNT embryosshowed significantly lower rates of development to theblastocyst stage than non-transgenic ones. To investigatenormal gene expression, RNA was extracted from tenblastocysts derived from parthenogenesis, IVF, non-transgenic,and transgenic SCNT embryos and reverse-transcribed tosynthesize cDNA. The cDNA was then subjected to PCRamplification and semi-quantified. More DNMT1 mRNA wasdetected in the transgenic SCNT group than the other threegroups. Hsp 70.1 mRNA was detected in the IVF embryos, whilelower levels were found in SCNT and parthenogenetic embryos. Mash2 mRNA was present at the highest levels in transgenicSCNT embryos. In conclusion, the higher levels of methylationand lower protein synthesis after heat shock in the transgenicSCNT embryos expected based on our results may cause lowerembryonic development.

개 감돈포경의 2례

조종기,이소현,현상환,김대영,이병천,황우석 한국임상수의학회 2000 한국임상수의학회지 Vol.17 No.2

Paraphilmosis, is a condition in which the extruded penis cannot be withdrawn back into the preputial cavity. In this study, the 2 dogs that showed prolonged erection. exposed penis from the sheath and hair surrounding the prepural orifice for several days, were ana1ysis of blood and urine ard carried out surgical treatment. In urinalysis, there were struvites, spermuria and bactera (streptococci) in urine. Firstly, these dogs were treated with non-surgical method, however severe necrosis of the Penis was developed form prolonged exposure and vascular compromise. Finally, partial penile amputation and preputial lengthening were performed and resulted in successful treatment.

Demecolcine-assisted Enucleation에 의한 소 형질 전환 핵이식란 생산

조종기,손정민,이두수,윤기영,신상태 韓國受精卵移植學會 2006 한국동물생명공학회지 Vol.21 No.2

본 연구는 소 형질 전환 체세포 핵이식에서 용이한 탈핵을 위해 demecolcine을 이용할 시 탈핵율과 핵이식란의 발육능을 높이기 위한 최적의 조건을 알아보고자 실시되었다. 도축장 유래 미성숙 난자를 18시간 체외성숙 후 제1극체가 확인된 성숙 난자를 0.1, 0.2, 0.4 및 0.8 ug/ml의 demecolcine이 첨가된 배지에서 1시간 더 처리한 다음 세포막이 돌출되어 있는 난자를 체세포 핵이식에 공여하여 각 군간 배반포로의 발육능을 비교하였