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      • 개 원발성 면역매개성 혈소판 감소증 증례

        유찬,임수정,이선희,박형진,김태신,송은식,김덕환,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2009 動物醫科學硏究誌 Vol.16 No.1

        A 13-year-old, castrated male, Maltese-dog was admitted to the Veterinary Medical Teaching Hospital of Chungnam National University with the history fo petechiae. On physical examination, she had petechiae and ecchymoses at her back, bilateral inguinal region, and inner part of ear pinna. CBC indicated neutrophilia and severe thrombocytopenia. A few platelets, no autoagglutination of RBC, and no spherocyte were observed. Coagulation profile demonstrated normal PT, and aPTT. No significant findings was not found on serum biochemical profile and electolytes test. FNA of a splenic mass which was found on the abdominal radiograph and sonograph demonstrated extramedullary hematopoiesis, Proteinuria was observed on urinarysis. Primary immune-mediated thrombocytopenia was diagnosed by ruling out of other underlying disease, severe thrombocytopenia, and response to immunosuppressive therapy. Prednisone and antibiotics were administered orally and parenterally, respectively. After altering prednisone to azathioprine, the number of platelets was recovered to normal range and petechiae and ecchymoses were improved.

      • PLZT 세라믹을 이용한 SAW Filter의 특성

        이수대,이찬구,안형주,문준규 경남대학교 신소재연구소 2003 신소재연구 Vol.15 No.2

        현재 사용되고 있는 SAW 필터 기관물질 중 세라믹 기관은 다공정과 생산에 따른 물성의 재현성 부족을 제외한다면 단결정 기관에 비해 생산단가의 저렴화, 생산공정의 단순화 및 대량생산의 측면에서는 훨씬 경쟁력이 있다. 따라서 본 연구에서는 고온 압축성형법에 의해 1235℃의 온도와 200㎏/㎠의 압력에서 30시간동안의 제조조건에서 조성비 x/65/35(x=5-8)인 PLZT 세라믹 기관들을 제조하여 SAW필터로써의 응용가능성을 살펴보았다. 각 조성별 유전을, SAW 전파 속도, 기계결합계수 등을 측정 비교한 결과 SAW 필터 기관물질로 가장 적합한 조성비는 7/65/35였다. 이 조성비로 제작한 SAW 필터에서 상대적으로 양호한 출력 특성을 얻었고 단결정 기관으로 제작한 SAW 필터에 버금가는 특성을 확인할 수 있었다. The single crystal substrate has been the industrial standard for the design of SAW filters for a long time. However, the ceramics substrate had more simple fabricated process than the crystal. In this study, it was attempted that single crystal was substituted for PLZT(La/Zr/Ti = x/65/35, x=5∼8 at. %) ceramics. The ceramics substrate was prepared by hot-pressed method at temperature 1235C, 200㎏/㎠, 30hrs. The real permittivity, SAW velocity and mechanical coupling factor of PLZT ceramics were measured for a different La mol% content. In the results, we could observed that 7/65/35 composition SAW filter had a good characteristics of frequency response.

      • Zn₄SnSe_(6):Co^(2+) 단결정의 물성에 관한 연구

        이우선,오금곤,최창주,송찬일,김형곤 조선대학교 에너지.자원신기술연구소 2001 에너지·자원신기술연구소 논문지 Vol.23 No.2

        In this paper, author describe the undoped and Co^(2+)-doped Zn₄SnSe_(6) single crystals were grown by the chemical transport reaction(CTR) method. For the crystal growth, the temperature gradient of the CTR furnace was kep a t 700℃ for the source aone and at 820℃ for the growth zone for 7-days. I t was found from the analysis of x-ray diffraction that undoped and Co^(2+)-doped Zn₄SnSe_(6) compounds have a monoclinic structure. The optical absorption spectra obtained near the fundamental absorption edge showed that these compounds have a direct energy gaps.

      • 진행성 위암에 동반된 위 칸디다증 1예

        이두영,김성호,선제형,박진석,손존광,선홍주,이승,박찬국 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

        Gastric candidiasis is an uncommon disorder. It is an opportunistic pathogen in immune compromised individuals, alcoholics, persons treated with broad-spectrum antibiotics, immunosuppressive and chemotherapeutic agents. Besides, the use of drugs that reduce the gastric acid production may be a cause of gastric candidiasis. We experienced a case of gastric candidiasis following advanced gastric adenocarcinoma. A 85-year-old woman was admitted to our hospital because of epigastric soreness. Endoscopic findings revealed a large ulcero-infiltrating mass with yellow exudate at cardia of the stomach, which suggested an advanced gastric cancer. Endoscopic biopsy revealed spores and pseudohyphae infiltrating through the ulcerated stomach wall, diffuse infiltration of tumor cells and abortive tumor glands. After treatment with fluconazole 100 mg daily for 21 days, no evidence of the gastric candidiasis was seen on endoscopic biopsy and pathologic findings. The case is herein reported of gastric candidiasis following advanced gastric adenocarcinoma along with a review of corresponding literature.

      • 마찰력과 열처리에 따른 아크용사 및 아크용접된 Fe-Cr-B 합금 피복층의 변화

        이찬규,유인석,김강형,구본흔,박맹로 國立 昌原大學校 産業技術硏究所 1995 産技硏論文集 Vol.9 No.-

        Variations of arc thermal sprayed and arc welded Fe-Cr-B alloy coating with frictional loading and heat treatment were investigated by means of X-ray diffraction, optical microscopy, scanning electron microscopy, electron probe microanalysis and hardness test. The as-coated layers were shown to be crystalline state but peaks with the frictional loading largely disappeared in X-ray diffraction profiles. The splat is relatively wavy with the boundary in arc thermal spray coating. After heat treatment, the amount of porosity was found to be decreased and the intersplat distance was increased. As annealing temperature increased, interface layer for arc welding coating increased by the diffusion of Cr atoms. The wear type observed in arc thermal spray coatings is splat delamination. The hardness of the arc thermal spray coation layer was superior to that of the arc welding layer. Hardness of coated layer is reduced and microstructures become to be uniformed by the heat treatment.

      • 생후 6일째(P6) 쥐와 성체 쥐의 해마체에서 시냅스의 발달과 프로테아좀 활성에 관한 연구

        이찬혁,김형태,서혜명 한양대학교 이학기술연구소 2005 이학기술연구지 Vol.8 No.-

        유비퀴틴-프로테아좀 시스템(ubiquitin-proteasome system: UPS) 은 세포내에서 비정상적인 단백질을 분해하는 기능을 담당하며, 그기능의 상실은 생체의 비정상적인 발달단계나 여러 퇴행성 신경질환의 병리학적 진행을 이해하는데 중요한 것으로 생각된다, 본 연구에서는 생후 6일째의 쥐(P6) 와 성체 쥐 뇌의 해마체에서 시냅스의 발달을 대표할수 있는 nerve growth factor(NGF)와 synaptophysin 의 발현 정도를 측정하고 더불어 프로테아조 활성의 차이를 알아보고자 하였다, 먼저 우리는 P6쥐 의 해마체에서 성체 쥐에 비하여 NGF의 발현이 1.3배 증가된 것을 확인하였고, 또한synaptophysin의 양이 특이적으로 감소된 것을 볼수 있었다, 흥미롭게도 P6쥐의 해마체에서 성체 쥐와 비교하여 유의성 있게 높은 프로테아좀 활성을 관찰 할수 있었다, 이와 같은 연구를 통하여 쥐 뇌의 발달 과정에 있어서 프로테아좀 활성의 조절은 시냅스의 발달과 밀접하게 연관되어 있다고 추정된다. Dysfunction of ubiquitin-proteasome system (UPS)has been proposed or implicated in the pathological processing of several neurodegenerative diseases and abnormalities in development . To address th differences of UPS in the sysnaptic development we determined the proteasome activities in the hippocampus of postnatal day 6 (P6) and adult rats. Using ELISA and western blot we found that the hippocampal NGF expression level is 1.3 times higher and synaptophysin level is significantly lower in P6 compared to adult Interestingly P6 rats in development showed 3~5 times higher hippocampal proteasome activities compared to adults. These results suggest that ubiquitin-proteasome are potentially related to synaptic divelopment.

      • KCI등재

        고도처리 하수처리장 운전조건의 통계분석

        이찬형,문경숙 한국환경과학회 2005 한국환경과학회지 Vol.14 No.2

        Statistical analysis between operating parameters and effluent quality on advanced wastewater treatment plant was performed. Through factor analysis four factors derived varimax rotation were selected each plant. Four components explained 80%, 82% of the total variance of the process, respectively. The components on MLE plant were identified in the following order : 1) HRT increase and BOD load decrease by influent decrease, 2) Biomass, 3) SVI increase by internal return increase, 4) Microbial diversity by SRT increase. On A₂0 plant, we defined them as follows: factor 1, high MLSS by return rate increase, HRT increase by influent decrease; factor 2, biomass; factor 3, BOD of influent; factor 4 was relate to DO.

      • KCI등재후보

        대구지역 가로수잎의 중금속

        이찬형,윤현숙,박연준,권종대,노기철,장성환 한국환경과학회 2002 한국환경과학회지 Vol.11 No.12

        This study was conducted to determine the contents of heavy metals in leaves of roadside trees according to different growth stages in Daegu city. The orders of heavy metal contents in leaves of roadside tree and soil were Fe〉Mn〉Zn〉Pb〉Cu〉Cr〉Cd and Fe〉Mn〉Zn〉Cu〉Pb〉Cr〉Cd, respectively. The contents of heavy metals in leaves of roadside trees and soil showed an increasing tendency as the levels of traffic volume increased. The contents of heavy metals in leaves on October were higher than those on May.

      • Polymer Light Emitting Diode의 발광특성 연구 : A study on electoluminescence properties of PLED with poly [2-(2'-ethylhexyloxy)-5-methoxy-1,4-phenylenevinylene]

        이상협;배형철;송석태;한찬수;채희백 순천향대학교 기초과학연구소 2010 순천향자연과학연구 논문집 Vol.16 No.2

        In order to know how the [2-(2'-ethylhexyloxy)-5-methoxy-1,4-phenylenevinylene] (MEH-PPV) layer works in organic light emitting diode, two different types of devices were fabricated, which are MEH-PPV single layer devices and MEH-PPV/tris (8-hydroxy-quinoline)aluminium(Alq3) bilayer devices. On the indium-tin-oxide(ITO) glass anode MEH-PPV layer was first spin-coated, and the Alq3 layer and the aluminium(Al) anode were vapor-deposited sequentially. The devices shows a trend that has lower current, luminous efficiency in case the thickness of the device is larger. Some bilayer devices, however, show more improved performance than other devices of smaller total thickness. This results were discussed on the basis of improved exciton formation resulting from balanced carrier transport.

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