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전해질 불균형과 동반된 신경이완제 금단 악성 증후군 1예
선홍주,김성호,이두영,선제형,박진석,박옥영,신정현,김현리,이승 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.1
Electrolytcs disturbance is one of the common medical problems encountered in chronic schizophrenic patients. Recently, we experienced a case of a 50-year-o1d man schizophrenic patient with severe hypokalemia (K:1.62 mEq/L) and hyponatremia (Na:100.8 mEq/L), which developed after psychogcnic polydipsia, followed by projectile vomiting. Aftcr admission, patient presented dysphagia, rigidity, tremor and mental change. We first considered that those symptoms were caused bv electrolyte disturbance. Thcretbrc, we corrected hypokalemia and hyponatremia. However despite of appropriate fluid therapy with electrolytes correction, these symptoms not resolved. But, after administration of antrpsychotic drug, symptoms were alleviated. Wc concluded patient's symptoms may be attributed to withdrawal ncuroleptic malignant syndrome (WNMS). In chronic schizophrenic patient, patient's symptoms were not sufficient to differentiate between hypokalemic psychosis and an exacerbation of schizophrenia. We report a case with brief literature review. 저자들은 과다 수분 섭취와 사출성 구토로 인한 전해질 불균형 소견을 보인 만성 정신분열병 환자에서 수일간 투여 중단 하였던 항정신병 약물의 투여로 사지 마비와 경직, 연하곤란, 구음장애 등이 호전되었음을 관찰하고, 정신 분열병 환자의 급격한 임상 양상의 변화가 약물의 금단에 의한 정신 질환의 악화임을 임상적으로 경험하였기에 문헌 고찰과 함께 보고하는 바이다.
이두영,김성호,선제형,박진석,손존광,선홍주,이승,박찬국 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2
Gastric candidiasis is an uncommon disorder. It is an opportunistic pathogen in immune compromised individuals, alcoholics, persons treated with broad-spectrum antibiotics, immunosuppressive and chemotherapeutic agents. Besides, the use of drugs that reduce the gastric acid production may be a cause of gastric candidiasis. We experienced a case of gastric candidiasis following advanced gastric adenocarcinoma. A 85-year-old woman was admitted to our hospital because of epigastric soreness. Endoscopic findings revealed a large ulcero-infiltrating mass with yellow exudate at cardia of the stomach, which suggested an advanced gastric cancer. Endoscopic biopsy revealed spores and pseudohyphae infiltrating through the ulcerated stomach wall, diffuse infiltration of tumor cells and abortive tumor glands. After treatment with fluconazole 100 mg daily for 21 days, no evidence of the gastric candidiasis was seen on endoscopic biopsy and pathologic findings. The case is herein reported of gastric candidiasis following advanced gastric adenocarcinoma along with a review of corresponding literature.
이용국 ( Lee Yong Gug ),이용엽 ( Lee Yong Yeob ),손준광 ( Son Jun Gwang ),선홍주 ( Seon Hong Ju ),한상우 ( Han Sang U ),이지신 ( Lee Ji Sin ),박무림 ( Park Mu Lim ) 대한내과학회 2003 대한내과학회지 증례 특집호 65-5 부록3 Vol.0 No.-
Pernicious anemia is caused by the absence of intrinsic factor from autoimmune destruction of parietal cells. Patients with pernicious anemia are predisposed to the development of gastric cancer. We report here a case of pernicious anemia with early gastr