아세틸 콜린 유발 검사시 허혈성 심전도 변화와 흉통의 발생이 내피세포 기능장애에 미치는 영향

최철웅(Cheol Ung Choi),나승운(Seung-Woon Rha),김선원(Sun Won Kim),나진오(Jin Oh Na),임홍의(Hong Euy Lim),김진원(Jin Won Kim),김응주(Eung Ju Kim),한성우(Seong Woo Han),박창규(Chang Gyu Park),서홍석(Hong Seog Seo),오동주(Dong Joo Oh) 대한임상노인의학회 2010 대한임상노인의학회지 Vol.11 No.4

연구배경: 아세틸 콜린 유발 검사시 발생하는 흉통과 허혈성 심전도 변화가 아세틸 콜린에 의해 발생하는 관상동맥의 내피세포 기능에 어떤 영향을 주는지 알아보고자 했다. 방법: 흉통으로 내원하여 관상동맥 조영술과 아세틸 콜린 유발검사를 시행받은 1,085명의 환자를 대상으로 하였다. 아세틸 콜린 유발 검사를 하는 동안 허혈성 심전도 변화 및 흉통의 발생 유무에 따른 관상동맥 내피세포 기능의 특징을 비교하였다. 결과: 539명의 환자에서 아세틸 콜린 검사시 내피세포 기능 장애가 발생 하였다. 허혈성 심전도 변화가 있었던 그룹이 심전도 변화가 없었던 그룹보다 흉통이 더 많았고(78.1% vs. 60.8%, P=0.007), 관상동맥 조영술상 다발성 관상동맥 경련이 빈번하였고(59.4% vs. 40.6%, P=0.004), 관상동맥의 경련 정도도 더 심하였다(64.1% vs. 46.5%, P=0.006). 흉통이 있었던 그룹이 흉통이 없었던 그룹보다 허혈성 심전도 변화의 빈도가 더 높았다(14.7% vs. 7.5%, P=0.007). 또한 흉통이 있었던 그룹이 관상동맥 경련이 다발성으로 발생하는 경우가 많았고 (50.7% vs. 29.5%, P<0.001), 미만성으로 발생하는 경우가 많았고(87.1% vs. 75%, P<0.001), 관상동맥의 경련의 정도도 더 심하였다(51.6% vs. 43.5%, P=0.041). 결론: 아세틸 콜린 유발검사시 발생하는 허혈성 심전도 변화와 흉통은 관상동맥 경련의 정도와 경련이 발생하는 관상동맥 개수와 연관이 있다. Background: ECG changes and chest pain during acetylcholine (Ach) provocation tests may constitute important clinical parameters for Ach-induced endothelial dysfunction. We investigated the association between ischemic ECG changes and chest pain during the Ach-provocation test and angiographic characteristics of Ach-induced endothelial dysfunction. Methods: A total of 1,085 patients with anginal symptoms underwent diagnostic coronary angiography (CAG) and Ach-provocation tests. We compared angiographic characteristics of Ach-induced endothelial dysfunction according to the presence of ECG change and chest pain. Results: A total of 539 patients experienced Ach-induced endothelial dysfunction. Patients who experienced ECG change group suffered more frequent chest pain (78.1% vs. 60.8%, P=0.007), angiographically more frequent multiple coronary artery spasm (59.4% vs. 40.6%, P=0.004), and more severe coronary artery spasm (64.1% vs. 46.5%, P=0.006) than patients without ECG change. However, there was no difference in the length of endothelial dysfunction between the groups. The incidence of ischemic ECG changes in patients with chest pain was higher than in patients without chest pain (14.7% vs. 7.5%, P=0.007). Patients who experienced chest pain more often experienced multiple (50.7% vs. 29.5%, P<0.001), diffuse (87.1% vs. 75%, P<0.001), and severe coronary artery spasm (51.6% vs. 43.5%, P=0.041) than patients without chest pain. Conclusion: Ischemic ECG changes and chest pain during the Ach-provocation test are associated with multi-vessel involvement and severe coronary artery spasm. Chest pain is associated with the length of endothelial dysfunction, but ischemic ECG change is not.

보조호르몬요법을 받는 여성 유방암 환자의 모발 변화와 치료 실태에 대한 기초 연구

이재경 ( Jae Kyung Lee ),김창현 ( Chang-hyun Kim ),홍동균 ( Dongkyun Hong ),정경은 ( Kyung Eun Jung ),서영준 ( Young-joon Seo ),김창덕 ( Chang-deok Kim ),이진선 ( Jin Sun Lee ),권인선 ( In Sun Kwon ),박상현 ( Sanghyun Park ),이영 대한피부과학회 2021 대한피부과학회지 Vol.59 No.7

Background: Hormone therapy, which includes tamoxifen and aromatase inhibitors, is the most common adjuvant therapy used for breast cancer. However, only a few studies have reported endocrine therapy induced alopecia. Objective: We investigated the effects of long-term adjuvant hormone therapy on hair in patients with breast cancer, in addition to patients’ concerns and current treatment for hair loss. Methods: Patients completed a questionnaire that included information on self-perceived hair changes after each adjuvant therapy session, distress, and current treatment for hair loss. Using a folliscope, we measured hair density and thickness in each patient and in healthy controls. Results: The study included 93 patients with breast cancer (mean age 51.9±9.8 years). The density and hair thickness were 106.36±21.85 hairs/cm2 and 0.07±0.01 mm in the patient group and 147.86±30.67 hairs/cm2 and 0.07±0.01 mm in the control group (n=98, mean age 52.10±8.40 years), respectively. The mean hair density was significantly lower in the patient group than in the control group; however, no statistically significant intergroup difference was observed in hair thickness. Among 76 patients who perceived hair changes after adjuvant therapy, 71.1% (n=54) were distressed with regard to hair changes. However, only 7.8% of the patients, including two who were treated by dermatologists, currently received treatment for hair changes. Conclusion: Dermatologists should be familiar with hair changes in patients with breast cancer and provide appropriate education to encourage patients to consult dermatologists for hair loss and thinning after breast cancer treatment. (Korean J Dermatol 2021;59(7):521∼526)

월경전 불쾌기분장애가 식이패턴에 미치는 영향

이은정,홍인선,김선희,정은영,장은재 동덕여자대학교 생활과학연구소 2008 생활과학연구 Vol.13 No.-

The purpose of this study was to identify the change of the dietary pattern, food craving in accordance with menstrual cycle among women with the premenstrual dysphoric disorder(PMDD) and women with no premenstrual symptoms(Non-PMS). The 24 subjects were divided by two groups, PMDD group and Non-PMS group. And the change of dietary pattern and food craving were measured for 4 weeks according to the menstrual cycle. The frequency of meal, the amount of meal and the change of palatability of meat intake, fatty food, carbonate drinks, fruit, confectionery and caffeine containing beverage were more significantly increased in luteal and menstrual phase than follicular phase without regard to PMDD group and Non-PMS group, but there were no statistically difference between groups. The change of palatability of vegetable & alcohol were no difference among the phase without regard to PMDD group and Non-PMS group, and there were no statistically difference between groups. Above the findings showed that the change of women's dietary pattern has connection with the change of menstrual cycle. It is considered that unconsidered variables in this study could be applied for the therapy of premenstrual symptom or management method in connection with variable related to menstrual cycle the systematic study is requested.

묵논의 식생천이에 관한 연구

이창석,박현숙,유영한,홍선기 서울여자대학교 자연과학연구소 1998 자연과학연구논문집 Vol.10 No.-

폐경년도가 다른 묵논에서 식생요인과 환경요인의 변화를 분석하여 천이계열 및 천이의 추진 기작을 밝혔다. 조사지소는 경작 중인 논, 폐경 후 3년(초기 묵논), 7년(중기 묵논) 및 10년째의 묵논(후기 묵논) 및 묵논에 인접한 계곡림(극상림)의 5단계로 구분하였다. 경작 중인 논, 초기 묵논, 중기 묵논, 후기 묵논 및 계곡림에서 각 조사지소의 우점종으로 판단한 천이계열은 뚝새풀군락→사마귀풀군락→갯버들군락→오리나무군락의 순서로 나타났다. 천이단계별 우점종의 분포와 그것의 생활령을 분석하여 파악된 천이의 추진기작은 내성모델을 따르는 것으로 밝혀졌다. 천이단계에 따른 다양성지수의 변화에서 종품부도와 종다양성지수는 초기에 증가하고 중기에 감소하였다가 그 이후 다시 증가하는 경향을 보였으나 균등성지수는 큰 변화가 없었다. 직경급분포도에서 중기 묵논의 갯버들개체군은 정규분포형을, 후기 묵논의 것은 역 J자형을 보여 전자는 그들이 과거적 어느 한 시기에 동시적으로 출현하였음을 반영하고, 후자의 것은 그들이 현재 경쟁상태에 있음을 반영하였다. 후기 묵논에 성립된 오리나 무개체군의 직경급분포도는 역 J자형을 보여 그들이 침입단계에 있음을 반영하였고, 계곡립의 것은 정규분포형을 보여 그들이 안정상태에 있음을 반영하였다. 이러한 식생요인에 대한 분석 결과, 현재 논으로 이용되고 있는 지역의 잠재자연식생은 오리나무군락이 될 것으로 판단되었다. 천이의 진행에 따른 토양환경요인의 변화에서 수분한량은 초기 묵논에서 현저히 증가되었고, 중기 이후의 묵논에서 감소하였다. pH는 큰 변화를 나타때지 않았고, 유기물, N, P, K, Ca 및 Mg함량은 천이의 진행에 따라 증가하는 경향을 보였다. To clarify the vegetational sere and driving mechanism of succession, vegetation and soil environmental factors were investigated in the old paddy field with different in the lapsed years after abandonment, Study sites were divided into 5 stages of the paddy field under cultivation, the old paddy fields of the initial, middle and late stages, and the climax forest of the mountainous valley near to the abandoned paddy fields. Sere estimated from dominant species of above mentioned study sites was shown in the order of Alpecurus aequalis var. amurensis community, Aneilema keisak community, Juncus effusus var. decipiens community, Salix gracilityla community, and Alnus japonica communt. y. Driving mechanism of succession inferred from the distribution of dominant species in each successional stage and their life form was based on the tolerance model. Species richness and diversity indices steadily increased since the middle stage but evenness index did not show any distinct change. In frequency distribution diagrams of diameter classes, Salix gracilistyla population of the middle and the late stages showed normal and reverse J-shaped distribution patterns, respectively. Result of the former reflects that individuals composing of that poulation were invaded simultaneously in a given time of the past and that the latter suggests that they are in state of intraspecific competition. Distribution diagram of Alnus japonica population in the late stage showed reverse J-shaped distribution pattern reflects that those individulas are in the stages of invasion and that of the valley forest showed normal distribution pattern suggests that they are in stable stage. From the results of analyses on those vegetation data, it was interpreted that potential natural vegetation of the present paddy field might be Alnus japonica community. In changes of soil environmental factors with the progression of succession, soil moisture content rapidly increased in the initial stage and then decreased since the middle stage. Organic matter, N. P. K, Ca and Mg contents tended to increase with the succession stage but pH did not show any distinct change.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

Overlapping and unique toxic effects of three alternative antifouling biocides (Diuron, Irgarol 1051^®, Sea-Nine 211^®) on non-target marine fish

Moon, Young-Sun,Kim, Moonkoo,Hong, Chang Pyo,Kang, Jung-Hoon,Jung, Jee-Hyun Elsevier 2019 Ecotoxicology and environmental safety Vol.180 No.-

<P><B>Abstract</B></P> <P>The use of alternative biocides has increased due to their economic and ecological relevance. Although data regarding the toxicity of commercial alternative biocides in marine organisms are accumulating, little is known about their toxic pathways or mechanisms. To compare the toxic effects of commercial alternative biocides on non-target pelagic fish (flounder) embryos, we investigated the adverse effects of developmental malformation and transcriptional changes. Three biocides including Diuron, Irgarol 1051<SUP>®</SUP> and Sea-Nine 211<SUP>®</SUP> produced a largely overlapping suite of developmental malformations, including tail-fin fold defects and dorsal body axis curvature. In our test, the potencies of these biocides were ranked in the following order with respect to malformation and mortalities: Sea-Nine 211<SUP>®</SUP> > Irgarol 1051<SUP>®</SUP> > Diuron. Consistent with the toxicity rankings, the expression of genes related to heart formation was greater in embryonic flounder exposed to Sea-Nine 211<SUP>®</SUP> than in those exposed to Irgarol 1051<SUP>®</SUP> or Diuron, while expression of genes related to fin malformation was greater in the Irgarol 1051<SUP>®</SUP> exposure group. In analyses of differential gene expression (DEG) profiles (fold change of genes with a cutoff <I>P < 0.05</I>) by high-throughput sequencing (RNA-seq), genes associated with nervous system development, transmembrane transport activity, and muscle cell development were significantly changed commonly. Embryos exposed to Diuron showed changes related to cellular protein localization, whereas genes associated with immune system processes were up-regulated significantly in embryos exposed to Irgarol 1051<SUP>®</SUP>. Genes related to actin filament organization and embryonic morphogenesis were up-regulated in embryos exposed to Sea-Nine 211<SUP>®</SUP>. Overall, our study provides a better understanding of the overlapping and unique developmental toxic effects of three commercial booster biocides through transcriptomic analyses in a non-target species, embryonic flounder.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Developmental defects of the most commercially used booster biocides were investigated on non-target marine species. </LI> <LI> Sea-Nine 211® was most developmental toxic biocides among three biocides regarding malformation and mortalities analysis. </LI> <LI> Three biocides were produced common toxic effects associated with nervous system development. </LI> <LI> Genes related to immune system processes were variated in embryos exposed to Irgarol 1051<SUP>®</SUP>. </LI> <LI> Genes related to embryonic morphogenesis were up-regulated in embryos exposed to Sea-Nine 211. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

난치성 만성정신분열증 환자의 생활의 질에 미치는 정신사회치료 프로그램의 효과에 대한 예비연구

송동호,배민진,이종호,이홍식,김선경,서호석,김찬형,전지용 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.4

Objects : Recent studies of psychosocial adjustment after hospitalization have found that the combination of maintenance antipsychotic drug treatment and psychosocial treatment including psychoeducational program are highly predictive of social rehabilitation and reduction of subsequent relapse. Two groups of patients with refractory chronic schizophrenia were preliminarily compared to determine the effect of a psychosocial treatment program on the quality of life in refractory chronic schizophrenics in an open comparative trial. Methods : One group(N=11) was assigned to approximately six months of the psychosocial treatment program(including psychoeducation program and activity program such as interpersonal relationship program, social skill training, self management program, outings, etc), in a group format, twice a week and a fixed maintenance dosage of clozapine ; while scale(QLS) was used to provide an objective measure of changes in patient's psychosocial functioning and a general assessment of psychopathology was made using the Brief Psychiatric Rating Scale(BPRS). Results : Both BPRS total positive score and the QLS total score, especially in the intrapsychic foundation factor of the scale showed a statistically significant improvement in the psychosocial treatment group. But there was no significant change in both BPRS and QLS scores over a 6-month period in the non-psychosocial treatment group. A significant negative correlation was found between the negative symptom and changes of QLS total, instrumental role and common object and activities scores respectively after receiving a 6-month of the psychosocial treatment program. Conclusion : These results suggest that a psychosocial treatment program including the integration of psychoeducation and a skill training oriented activity program serve as an outpatient treatment modality to improve the quality of the life in refractory chronic schizophrenia. To further clarify the effect of psychosocial treatment in chronic schizophrenia, a randomized trial should be done.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

유아의 음악선호도 조사

홍지현,장선희 이화여자대학교 사범대학 교과교육연구소 2004 교과교육학연구 Vol.8 No.2

본 연구는 중ㆍ고등학생 및 대학생들의 음악양식에 대한 선호도를 파악하고 그 선호도에 미치는 연령,성별 그리고 곡에 대한 친숙도 요인들의 영향을 파악하는데 그 목적이 있다. 이를 위하여 서울의 중ㆍ고등학생 및 대학생 810명(중학생 303명, 고등학생, 284명, 대학생 223명)을 대상으로 5가지 음악양식(서양 클래식, 한국 대중음악, 재즈, 국악 록음악)에 대한 각 각 6곡 씩, 30곡에 대한 선호도와 친숙도를 검사하였다. 연구대상은 11세에서 33세까지의 남학생 378명, 여학생 432명으로 구성되었다. 음악선호도는 평균 37초 길이의 음악을 들고 선호도와 친숙도를 7점 리커드 척도에 표시하도록 하였고, 청취곡은 무작위로 순서를 배열한 두 가지형의 CD로 제작하여 사용함으로써 청취곡의 순서에 의하여 개별곡에 대한 선호도가 영향을 받는 것을 최소화 하고자 하였다. 음악양식 선호도에서는, 한국 대중음악을 가장 선호하였으며, 서양 클래식음악, 재즈, 그리고 록음악 순이었으며, 국악을 가장 덜 선호 하는 것으로 나타났다. 선호도와 친숙도는 모든 장르에서 양의 상관관계를 보이고 있으며 한국대중음악과 국악에서 가장 강한 상관관계를 보이고 있다. 성별에 따른 선호도는 여학생이 남학생보다 모든 장르에서 높은 선호도를 보이고 있으며, 특히 재즈와 국악에서 더욱 두드러진 결과를 보이고 있다. 중학생들의 선호도는 고등학생이나 대학생들에 비하여 낮았으며, 고등학생들의 선호도는 18세경까지는 지속적으로 증가하고 그 이후 대학생 연령층에서는 비교적 안정된 선호도를 형성하는 것으로 나타났다. 중학생들은 서양 클래식음악을 가장 선호하며, 고등학생들은 한국 대중음악 그리고 대학생들은 재즈음악이 가장 선호하는 양식으로 본 연구에서 조사되었다. 중다회귀분석결과, 선호도는 그 곡에 대한 친숙도에 의해 가장 잘 예견될 수 있으며 그 다음이 연령, 그리고 성별 순으로 나타났다. 국악장르의 청취곡들은 모두 잘 알려지고 교과서에 수록 된 곡들임에도 불구하고 선호도와 친숙도가 가장 낮은 장르로 나타나고 있으나 선호도는 18세부터 대학생 연령까지 지속적으로 상승하고 있었다. 본 연구의 결과는 미국에서 진행된 르불랑과 그의 동료들(1996)의 연구보다는 홍콩의 훵과 그의 동료들(2000)의 연구결과와 더 공통된 결과를 보이고 있다. 이것은 최근에 이루어지고 있는 비교 문화적 선호도 연구와 그 맥락을 같이 하는 것으로서 문화 배경적 선호도 연구경향에 대한 긍정적인 시사점을 제시하고 있다고 할 수 있다. This study is to investigate the music style preferences of secondary school and college students, and also to determine the effect of age, gender and familiarity on the music excerpts. A total of 810 students participated in the study and data were collected on their music style preference among Western classical music, Korean popular songs, Jazz, Korean Traditional Music and Rock Music. A. preference opinion form, with 30 music listening excerpts on CD was utilized. A seven-point preference scale was used for each listening excerpt. The participant (n=810) in the study ranged from age 11 to 33 years, and the gender ratio is 378 male ro 432 female students.. Results of multi regression showed that familiarity, age and gender had significant main effects (p<.01) on the style preference in general. The preference of female students was higher than male students in all six styles of music excerpts. The preferences tended to increase as the subjects age increased. Based on the results, the study has reached the following conclusions: First, Korean popular music was the most preferred music style, followed by Western Classical Music, Jazz, and Rock. Korean traditional music was the least preferred style. Significant changes in preference for all music styles generally occurred at about the age 18. Second, music style preferences differed by age and gender. Student aged12-14 years showed the lowest preference among the three students groups. High school students (age 15-18) showed the highest preference forKorean popular music as their most preferred style. College students (age 18 plus) demonstrated more stable preference tendency in all the music excerpts. Third, although the excerpts of Korean Traditional Music were selected from the textbooks used by junior and high school students, the students' familiarity level was very low. However, the preference for Korean traditional music showed the most dramatic increase of preference as their age increased.

Oil Contents and Fatty Acid Composition of Korean Perilla (Perilla ocimoides L.) Collections

Hong,Seong-Taek,Son,Suk-Yeong,Jong,Seung-keun,Rho,Chang-Woo,Yun,Jong-Sun 한국자원식물학회 2003 Plant Resources Vol.6 No.3

This study was carried out to obtain informations on the variations of oil content and fatty acid composition among 90 Korean perilla collections. Average oil content of 90 perilla collections was 44.2% with a range from 29.7% to 61.9%. Perilla collections with late-maturing, super-large seed and gray seed coat showed higher oil content than other types in general. Average saturated fatty acid content in perilla oil was 9.0% with a range from 8.2% to 10.7%, while average unsaturated fatty acid content varied from 89.3% to 91.8% with a mean of 91.0%. Contents of saturated and unsaturated fatty acids were not related to maturity. There were no differences in the contents of saturated and unsaturated fatty acids according to maturity. Linoleic acid and linolenic acid contents were the highest in the super large-sized group(15.5%) and in the large-sized seed group(61.4%), respectively, while contents of fatty acids among the perilla collections were variable with different seed coat colors. Most of the traits studied were not significantly correlated with oil content, but linoleic acid($\omega$ 수식 이미지-6) content was negatively correlated (r=-0.217*) with linolenic acid(ω-3) content.