지난 2년간의 학회지 "신경정신의학" 심사 평가보고

김찬형,김세주,김도관,김성곤,박원명,송동호,박용천,이영문,오강섭,정영철,이상열,김주한,이동영,이헌정,함병주,김율리,김문두,김정진,이강욱,천근아,김재진,홍진표,홍승철 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

신규 3작용성 메타크릴레이트의 치과용 광중합형 콤포짓트 레진용 단량체로서의 응용 연구

김중곤,정찬문,김민성,김광만,김경남 大韓齒科器材學會 2001 대한치과재료학회지 Vol.28 No.4

Tris[4-(2-hydroxy-3-methacryloxypropoxy)phenyl]methane(THMPM) was prepared easily from triphenylolmethane triglycidyl ether in good yield. As compared with composite resin formulated with difunctional bis-GMA, the physical properties of a newly developed composite resin formulated with trifunctional THMPM was evaluated. Cytotoxicity and acute toxicity of composite resin based on trifunctional THMPM evaluated according to ISO standard method. The depth of cure of the composite resin based THMPM was higher than that of the bis-GMA composite. There were no significant differences in flexural strength and water sorption between the composites resin based on THMPM and bis-GMA. The water-solubility value for the light-activated composite resins formulated with THMPM was much lower than that for a control bis-GMA composite. According to cytotoxicity evaluation, the composite resin based on THMPM showed very mild cytotoxicity with the response index of between 0/0 and 1/0. No acute toxicity of composite resin formulated with trifunctional THMPM was also observed. It is believed that THMPM is promising candidate for application as a photocurable dental composite resin.

위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예

김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.

실리카흄을 흔입한 고강도 콘크리트 개발

홍창우,김태경,김경진,김성환,김남윤,심도식,이정호,윤청호,백민경,원치문,박제선,이주형,정경일 강원대학교 석재복합신소재제품연구센터 1996 석재연 논문집 Vol.1 No.-

콘크리트 구조물이 대형화됨에 따라 설계단면이 증대되어 상대적으로 많은 경제적 손실을 부담하게 된다. 따라서 단면을 감소시키면서도 소요의 하중에 안전한 구조물을 건설하기 위해서는 우선적으로 구조물 건설에 기초가 되는 고품질, 고내구성의 고강도 콘크리트 개발이 절실히 요구된다 본 연구에서는 일정 시멘트비 및 혼화재 비율하에서 소요의 워커빌리티가 확보되는 고강도 콘크리트를 시간과 온도의 변화에 따라 증기 양생하여, 압축, 인장, 휨강도 뿐만 아니라 파괴특성을 실험적으로 연구하였다. 시료 제작시 시멘트 입자 사이의 공극 및 불연속 영역을 충전하여 고밀도화하기 위한 콘크리트용 혼화재로 시멘트 비표면적이 상당히 작은 초미립 분말인 실리카흄을 이용하였다. 또한 AE감수제 및 고성능 유동화제를 사용하여 혼화재의 첨가에 의하여 발생될 수 있는 워커빌리티의 감소를 방지하였다. 실험결과에 의하면 일정 양생 지속 시간하에서 온도의 증가에 따라 콘크리트의 압축, 인장 및 휨강도가 전반적으로 증가하였다. 동일하게 일정 온도하에서 양생 지속시간이 커짐에 따라 강도들이 증가됨을 알 수 있었다. 따라서 상대적으로 높은 온도와 긴 지속 양생 조건하에서 파괴에 대한 저항력이 크게 나타났다. The compressible, tensible, and flexibleresistance of the high strength concrete is analyzed by the experimentation in the present study. For the test, we cure several samples with the silica fume as a mixture being become dense the spaces between the particle of cement under the variation of both the temperature and the curing-interval. Then, the superplasticizer and the ezcon are also used to satisfy the required workability for construction. The compressible, tensible, and flexible resistances to a stress are increased as increasing the temperature and the time interval for the curing. Therefore it is concluded that the overal fractural and mechanical properties is improved by mixing the silica fume into the cement.

濟州韓牛의 飼養管理와 繁殖狀況에 關한 硏究 : 第1報 濟州韓牛에 있어서 放牧期間 中 牧野狀態가 體重變化에 미치는 影響 1. The Effect of Grass Quality on the Daily Weight Gain of Jeju Native Cows During the Granzing Period

金承贊,金重桂,金文哲 제주대학교 1982 논문집 Vol.14 No.-

濟州地域 部落共同 牧場의 草地狀態 및 氣象現況이 飼育中인 家畜의 增體에 미치는 영향을 究明하기 위해 6個部落 共同牧場(영남,해안,회천,용강,오라,하원)에서 成牝年 415두의 體重과 그 牧場의 草地狀態를 調査한 結果는 다음과 같다. 1. 試驗이 實施되는 部落共同牧場의 草地面積 197.8ha중 改良草地比率은 66%이며 頭當面積은 0.9ha였다. 2. 名 牧場 共히 牧草 보다 野草의 乾物收量이 높으며 2回 收穫 中 牧草는 初期收量(1734㎏/ha>1459㎏/ha)이 높았고 野草는 後期收量이 (2025kg/ha<4734kg/ha)높았다. 3. 野草의 粗蛋白質 含量은 施肥草地(12.05%)가 無肥草地(7.87%) 보다 높았으나 牧草는 施肥에 關係없이 비슷한 傾向이였으며 粗纖維含量은 無肥草地가 높았다. 4. 月平均 增體量은 6月 347.0kg, 7月 358.5kg, 8月 384.5kg, 9月 414.2kg, 10月 421.8kg로서 放牧期間中 頭當 總 增體量은 74.8kg이며 月別 1日 增體幅은 9月에 頭當 1.05㎏으로서 本 試驗期間中에 가장 크다. 5. 日當 平均 增體量은 하원 0.89kg, 해안 0.81kg 영남 0.71kg, 회천 0.60kg, 용강 0.58kg과 오라 0.15kg 順位였으며 全體平均 日當增體量은 0.61kg이였다. The study was carried out to investigate the effect of grass quality and climate on weight gain. Six co-operative village farms were surveged which reared Korean native and Korean cross-bred cows. The results obtained were as follows; 1. The farms examined had 66% improved pasture and a stocking rate of 0.9ha per head. 2. On all the farms, the total dry matter content of native pasture was more than that of the improved pasture. 3. In the case of native pasture the crude protein content when fertilized(12.05% cp compared to 7.87%). On the other hand, there was no difference in crude protein content between fertilized improved pasture and non-fertilized. The crude fibre content of improved and unimproved pasture decreases when fertilized. 4. Body weights during June, July, August, September and October were 347.0kg, 358.5kg, 384.5kg, 414.2kg and 421.8kg respectively. 5. The average daily weight gain on each farm was 0.89kg on Hawoen, 0.81kg on Yeong Nam, 0.71kg on Hoicheon, 0.60kg on Young Kang and 0.15kg on Oh Ra: The total weight gain of all the cows on all the farms was 76.8kg with an average daily weight gain of 0.6kg per cow.

태권도수련이 초등학생의 지적, 정서적 및 사회적 생활태도에 미치는 영향 : focusing on the northern area of Kung-Ki province

김관현,김찬겸,문원배 龍仁大學校 體育科學硏究所 1998 體育科學硏究論叢 Vol.8 No.1

The subject of this research is to offer the materials to help Tae-Kwan-Do education of children. School grade, level of Tae-Kwan-Do and year of practice were set as independent factors to investigate the effects of Tae-Kwan-Do practice to intellectual, emotional and social behavior of elementary student, and aspects of school life, emotional development, manner of living and physical development were set as dependent factors to find out how much effect does Tae-Kwan-Do had on children's social development. Questionnaires were structured with 5 point scale and sent to total 126 persons to verify the theory that school grade, level of Tae-Kwan-Do, practice year will result a difference in school life, emotional development, manner of living and physical development. The conclusion of the study form this investigation is ans followed: 1. Tae-Kwan-Do practice results the similar difference (p(.01) in emotional development according to the school grade 5-6 and grade 3-4 showed the similar difference from later analysis. 2. Each level of Tae-Kwan-Do in school life showed similar difference (p(.05) and later analysis showed that between level 3. and level 1 and lower results similar difference. Aspect of emotional development also showed similar difference that later analysis showed that between level 3. and 1 lower results similar difference. 3. The year of practice in school life showed similar difference (p(.01) and later analysis showed that between 3 year, and less than one year results similar difference. The year of practice in emotional development showed very similar difference (p(.001) and later analysis showed that between longer 3 years, 2 years and less than one year showed similar difference. Also in physical development showed very similar difference and more than 3 years and less than one year showed similar difference from later analysis.

황화 Ni-Mo/γ-Al₂O₃ 촉매상에서 1-Hexene의 수소화반응에 관한 Thiophene의 영향

김경림,유성현,김문찬,박해경 연세대학교 대학원 1992 延世論叢 Vol.28 No.1

The effect of thiophene on hydrogenation of 1-hexene over sulfided NiMo/γ-Al2O3 catalyst was studied in a fixed bed continuous flow reactor. The ranges of experimental conditions were at the temperatures between 200 and 350℃, the atmospheric pressure, the concentrations of thiophene between 0 and 0.04 mol% and the contact times between 0.04 and 0.1 g cat.h/mL. The hydrogenation increased with increasing temperature but isomerization decreased with increasing temperature. Total conversion and hydrogenation decreased with increasing concentration of thiophene but isomerization increased with increasing concentration of thiophene. The reaction order of 1-hexene was pseudo first with respect to 1-hexene and the activation energy for 1-hexene was found to be 8.8 kJ/mol over sulfided NiMo/γ-Al2O3 catalyst by Arrhenius plot.

정신분열증 환자에서 주관적 음성증상경험의 임상적 의의

김지웅,김찬형,구민성,손석한,박진철,최문종,이은철,윤도준,이홍식 대한신경정신의학회 1999 신경정신의학 Vol.38 No.1

연구목적 : 현재까지 정신분열증의 음성증상평가는 주로 객관적인 평가에만 의존해왔기 때문에, 환자들이 주관적으로 직접 경험하는 음성증상의 평가는 경시된 경향이 있었다. 그러나 실제 많은 정신분열증 환자들은 음성증상을 자가하고 있다. 특히, 개관적인 양성 및 음성증상이 관찰되지 않는 경우에도 환자 본인은 음성증상으로 괴로워한다는 이전의 연구보고들이 있었다. 따라서 저자들은 주관적인 음성증상경험과 개관적인 양성증상 및 음성 증상, 우울증상, 불안증상, 추세외로증상과의 상관성을 알아봄으로써 정신분열증의 정신병리에 있어 주관적 음성증상의 존재를 규명하고, 정신분열증 정신병리의 발생기전을 유추해보며 이차적 음성증상과의 관계를 규명하고자 하였으며. 이러한 연구가 정신분열증 정신병리를 이해하는데 도움을 줄 수 있을 뿐 아니라 환자를 공감적으로 이해하는데 도움을 줄 수 있을 것으로 생각되어 본 연구를 시행하였다. 방 법 : DSM-Ⅳ 진단기준의 정신분열증 진단기준에 해당하는 환자를 대상으로 하였다. 주관적인 음성증상의 평가를 위해서 Scale for the Subjective Experience of Negative Symptoms : Korean version(KSENS)을 이용하였고, 개관적인 정신분열증 정신병리의 평가는 Positive and Negative Syndrome Scale(PNASS)를 이용하였다. 우울증상, 불안증상, 추세외로증상의 평가를 위해서 각각 Hamilton Rating Scale for Depression(HAM-D), Hamilton Rating Scale for Anxiety(HAM-A), Extrapyramidal Symptoms Rating Scale(ESRS)을 이용하였다. 각 정신병리척도 점수간의 상관성은 Spearman 상관계수를 이용하여 분석하였다. 결 과 : K-SENS 24항목 중에서 환자가 이를 불편한 것으로 경험하고 있는 항목의 비율과 PANSS 양성척도점수 사이에는 유의한 상관점이 있었으며 (r=-0.40, p〈0.05), 양성증상 중에서도 특히 과대성(r=-0.46, p〈0.05), 의심/피해(r=-0.34, p〈0.05), 적개심(r=-0.52, p〈0.05) 등의 증상과 유의한 상관관계를 보였다. K-SENS 24 항목 중에서 환자가 이를 불편한 것으로 경험하고 있는 항목의 비율과 PANSS 전체점수(r=-0.25, p〉0.05), PANSS 음성척도점수(r=-0.20, p〉0.05), PANSS 일반정신병리척도(r=-0.08, p〉0.05),와는 각각 유의한 상관성이 없었다. K-SENS 24항목 중에서 환자가 이를 불편한 것으로 경험하고 있는 항목의 비율과 HAM-D 점수(r=-0.01, p〉0.05), HAM-A 점수(r=-0.11, p〉0.05), ESRS 총점(r=0.34, p〉0.05)은 각각 유의한 상관성이 없었다. 결 론 : 본 연구결과에서, 정신분열증 환자들이 불편한 것으로 경험하는 주관적 음성증상과 과대성, 의심/피해, 적개심 같은 양성증상은 역상관관계가 있었으며, 이러한 결과를 바탕으로 양성증상이 주관적으로 불편하게 느끼는 음성증상에 대한 가능성과, 혹은 양성증상이 심할 경우, 이에 압도되어 음성증상을 주관적으로 느끼지 못할 수 있다는 가능성이 시사되었으며, 향후 종적인 연구를 통해 이를 규명해 볼 필요성이 제시되었다. 주관적인 음성증상경험과 우울증상, 불안증상, 추세외로 증상과는 상관성이 없는 것으로 나타나서 이들 증상과는 독립적인 증상임을 시사한다. Objective : Since the evaluation of negative symptoms has depended on the clinician's objective observation, the patients subjective experience of negative symptoms has been neglected. However, in fact, a lot of patients are aware of their negative symptoms. There are several reported suggesting that patients suffer from the subjective experiences of their deficit symptoms, even though the objective positive and negative symptoms cannot be observed. Under these circumstances, we have attempted this study with the idea that it would be helpful in understanding the psychopathology of schizophrenia. Also it would help clarifying the relationship between subjective experience of negative symptoms and objectives positive and negative symptoms, depression anxiety symptoms, and extrapyramidal symptoms. Method : All the 37 patients satisfied the diagnostic criteria of DSM-Ⅵ for schizophrenia. The subjective experiences of negative symptoms were evaluated using Scale for the Subjective Experience of Negative Symptoms : Korean version(KSENS), and for the depression, anxiety, extrapyramidal symptoms, we used Hamilton Rating Scale for Depression(HAM-D), Hamilton Rating Scale for Anxiety(HAM-A), and Extrapyramidal Symptoms Rating Scale(ESRS). The correlation between each psychopathology was tested by calculating Spearman correlation coefficient. Results : There was a significant correlation between the ratio of items experienced as uncomfortable symptoms among 24 items of K-SENS, and the score of PANSS positive subscale(γ=-0.40, p〈0.05), Among the positive symptoms, grandiosity(γ=-0.46, p〈0.05), suspiciousnes/persecution(γ=-0.34, p〈0.05), and hostility(γ=-0.52, p〈0.05) showed a significant correlation with the ratio of items experienced as uncomfortable symptoms among 24 items of K-SENS. There was no significant correlation between the ratio of items experienced as uncomfortable symptoms among 24 items of K-SENS, and PANSS total score(γ=-0.25, p〉0.05), or negative subscale score(γ=-0.20, p〉0.05), or general psychology subscale score(γ=-0.08, p〉0.05), respectively. There was no significant correlation between ratio of items experienced as uncomfortable symptoms among 24 items of K-SENS, and HAM-D(γ=-0.01, p〉0.05), or HAM-A(γ=-0.11, p〉0.05), ESRS(γ=0.34, p〉0.05), respectively. Conclusion : These revealed that the negative correlation between the subjective negative symptoms experienced as an uncomfortable ones and the objective symptoms such as grandiosity, suspiciousness/persecution, and hostility. From these results, the possibility that positive symptoms are used as a defense to hide from the negative symptoms because they are overwhelmed by their positive symptoms, is suggested. These results also suggest that subjective experiences of negative symptoms are independent from depression, anxiety and extrapyramidal symptoms.

작업롤의 파손과 크롬함량에 따른 마멸특성

김순경,전언찬,이승수,김문경 동아대학교 공과대학부설 생산기술연구소 1996 生産技術硏究所硏究論文集 Vol.1 No.2

Work rolls used in cold rolling mills must have outstanding wear resistance and very little plastic deformation. Thus, these rolls require a higher surface hardness and hardening to a greater depth. To meet these requrements, the rolls, in general, have basic chemical composition of 0.7 to 1.0% carbon and 1.0 to 5.0% chromium(Cr), plus a small amounts of special elements, and are subjected to intensive water quenching and tempering at low temperature to provide a surface hardness of over 90 shore. This test results are as follows. Deflection and fracture load of 5% Cr material are than those of 3% Cr material and show flat curve from surface to subsurface. It will be clear that 5% Cr work roll has a superior resistibility against wear and abrasion comparing with 3% Cr work roll. The improvement of wear and abration in 5% Cr work roll will be achieved by the large amount of spheroidal carbide. In grindability and polish, 5% Cr work roll will be a little inferior comparing with 3% Cr work roll.

정신질환의 수술적 치료

김문찬,이태규 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.1

Since Moniz began his clinical investigation, almost a century has passed. Cycles of acceptance and rejection of this theory have been its hallmark-more so than for any other method of treatment. The introduction of psychotropic medications reduced the need for psychiatric surgery but did not eliminate it. In the 1970s there was great agitation over the possibility that psychosurgery would be used. It is essential, however, to be ever mindful that these neurosurgical attempts to benefit the psychiatrically disabled do have the potential to alter human behavior in the general population. This review aimed at giving a compact and systemized account of the clinical guidelines in the management of patients with psychiatric disorder.