Bloodstream Infections and Clinical Significance of Healthcare-associated Bacteremia: A Multicenter Surveillance Study in Korean Hospitals

Son, Jun Seong,Song, Jae-Hoon,Ko, Kwan Soo,Yeom, Joon Sup,Ki, Hyun Kyun,Kim, Shin-Woo,Chang, Hyun-Ha,Ryu, Seong Yeol,Kim, Yeon-Sook,Jung, Sook-In,Shin, Sang Yop,Oh, Hee Bok,Lee, Yeong Seon,Chung, Doo The Korean Academy of Medical Sciences 2010 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.25 No.7

<P>Recent changes in healthcare systems have changed the epidemiologic paradigms in many infectious fields including bloodstream infection (BSI). We compared clinical characteristics of community-acquired (CA), hospital-acquired (HA), and healthcare-associated (HCA) BSI. We performed a prospective nationwide multicenter surveillance study from 9 university hospitals in Korea. Total 1,605 blood isolates were collected from 2006 to 2007, and 1,144 isolates were considered true pathogens. HA-BSI accounted for 48.8%, CA-BSI for 33.2%, and HCA-BSI for 18.0%. HA-BSI and HCA-BSI were more likely to have severe comorbidities. <I>Escherichia coli</I> was the most common isolate in CA-BSI (47.1%) and HCA-BSI (27.2%). In contrast, <I>Staphylococcus aureus</I> (15.2%), coagulase-negative <I>Staphylococcus</I> (15.1%) were the common isolates in HA-BSI. The rate of appropriate empiric antimicrobial therapy was the highest in CA-BSI (89.0%) followed by HCA-BSI (76.4%), and HA-BSI (75.0%). The 30-day mortality rate was the highest in HA-BSI (23.0%) followed by HCA-BSI (18.4%), and CA-BSI (10.2%). High Pitt score and inappropriate empirical antibiotic therapy were the independent risk factors for mortality by multivariate analysis. In conclusion, the present data suggest that clinical features, outcome, and microbiologic features of causative pathogens vary by origin of BSI. Especially, HCA-BSI shows unique clinical characteristics, which should be considered a distinct category for more appropriate antibiotic treatment.</P>

보디빌딩 선수들의 시합 전·후 신체조성과 체력 및 혈관탄성도 변화와 영양섭취 실태연구

곽재준,박재성,하수민,백영호 釜山大學校 附設 體育科學硏究所 2013 體育科學硏究所 論文集 Vol.30 No.-

The purpose of this study were to investigate a study of body composition, physical fitness, change of vascular compliance and nutrient intake status a before and after bodybuilders match. In this study, participants were 6 bodybuilders. The analyzed data brought about the following results by using paired t-test with SPSS 20.0. The results of the research were as follows. In to body weight and BMI were significantly increased but sit and reach were significantly decreased after match. There was non significantly difference in vascular compliance. Calories, lipids, carbohydrates, fiber and ash had significantly increased after match than before match. Calcium, iron, sodium, potassium, vitamin A, retinol, vitamin B1, vitamin B6, niacin, vitamin C, vitamin E had significantly increased after match than before match. Therefore, Bodybuilders need correct regular diet habit and exercise prescription after match. 본 연구는 B광역시 남자 보디빌딩 선수 6명을 대상으로 신체조성, 체력, 혈관탄성도 및 영양소 섭취상태를 시합 전·후를 분석하는데 목적이 있다. 자료처리는 SPSS 20.0 프로그램을 이용하여 paired t-test를 실시하였고, 연구결과에서 다음과 같은 결론을 얻었다. 시합전에 비해 시합후에 체중과 BMI는 유의하게 증가하였고, 유연성은 유의하게 감소하였고, 혈관탄성도는 유의한 변화가 없었다. 그리고 열량, 지질, 당질, 식이섬유 및 회분은 시합 전 보다 시합 후 유의하게 증가하였다. 또한, 칼슘, 철분, 나트륨, 칼륨, 비타민 A, 레티놀, 비타민 B1, 비타민 B6, 나이아신, 비타민 C, 비타민 E는 시합 전 보다 시합 후 유의하게 증가하였다. 이상을 종합하여 볼 때, 시합 전보다 시합 후에 영양소의 섭취증가로 인해 체중이 증가하는 것을 알 수 있으며, 이상의 연구 결과에서 시합전, 후의 식습관, 맞춤형 운동처방 및 체계적인 컨디셔닝 관리가 요구된다.

인버터 制御車輛 電源用의 컨버터 制御特性

황준하,서영수,임영배 明知大學校 産業技術硏究所 1994 産業技術硏究所論文集 Vol.13 No.-

In this paper,the inverter-voltage source of AC Electrical Vehicle System has generally used voltage type PWM converter. A parallel operation of two single-phase voltage typed PWM converters used IGBT which achives the bidirectional power floe between a single phase AC supply and a DC bus voltage is described. The parallel operating system has reduced current ripple of a source than a single device operation, and made a converter capacity increased.Also,the voltage type PWM converter made the input current wave as sinusoidal wave, and performs the high power factor driving.

중소기업 CEO의 퍼스낼러티가 리더십유형과 부하의 직무만족에 미치는 영향

장정하,최광신,신준수 한국정보전략학회 2001 한국정보전략학회지 Vol.4 No.2

The major purposes of this thesis are to investigate the relationship between leadership styles(person oriented leadership and task oriented leadership) and the personality traits(locus of control, extrovert/introvert, A/B type, machiavellian, authoritarianism) of CEO in small-medium business and to verify the affectation of subordinate's job satisfaction on leadership styles and personality traits of CEO. Therefore, this paper is an important suggestion that trait theory of leadership connects with behavior theory of leadership. To achieve of this purposes, a questionnaire has been worked up through 369 workers and 49 CEO who had acted many years at Yeosu city. The results of this survey are as follows ; First, in the person oriented leadership, the personality traits of CEO has the significant relations with introvert locus of control, B type, low authoritarianism. And in the task oriented leadership, the personality traits of CEO has the significant relations with extrovert and high machiavellian. Second, the personality trait factors(introvert locus of control, B type, low machiavellian, low authoritarianism) except extrovert have affect on subordinate's job satisfaction. Third, the correlation between subordinate's job satisfaction and the person oriented leadership has higher than that of subordinate's job satisfaction and the task oriented leadership.

플러그셀 크기 및 용토가 거어베라의 묘생장에 미치는 영향

조문수,예병쾌,박윤영,전하준 한국환경농학회 2003 한국환경농학회지 Vol.22 No.1

양액재배용 거어베라 우량묘를 생산하기 위한 기초연구로 플러그셀 크기 및 용토가 묘생장에 미치는 영향을 조사하였다. 용토의 물리성을 측정한 결과 가비중, 진비중 및 공극율은 퍼얼라이트에서 가장 높게 나타났으며 수분보유량은 코코피트에서 가장 높게 측정되었다. 162, 129, 72, 50구 플러그셀 트레리별로 퍼얼라이트 코코피트 그리고 퍼얼라이트+코코제트(1:1)을 채우고 60일간 육묘하여 묘의 생육을 조사하였다. 묘의 엽수는 125구 코코피트 처리에서 가장 많았으며 엽면적은 50구 코코피트 처리에서 높게 나타났다. 신초와 뿌리의 생체중 및 건물중 그리고 엽록소 함량은 퍼얼라이트+코코피트 처리에서 높게 측정되었다. 플러그셀 크기가 클수록 유모 생장에 효과적이었으며 퍼얼라이트 단용 보다는 코코피트와의 혼용 용토에서 유묘 생육이 가장 양호하였다. This study was conducted to examine the effects of plug tray cell size and growth media on good seedling production of Gerbera hybrida Hort. Seedlings were worm for 60 days in 50, 72, 128, 162 cell trays continuing perlite, cocopeat and perlite+cocopeat(1:1, v/v). Perlite showed higher bulk density than cocopeat and perUte+cocepeat. Total porosity was greater in perlite, cocopeat and perlite+cacopeat in order. Cocopeat showed the highest water balding capacity. Number of leaves were greatest in 128 cell tray containing cocopeat. Leaf area was greatest in 50 cell tray containing cocopeat. Seedling growth was also better in plug tray of bigger cell size. Seedling growth of fresh and dry weight of shoot and root was much better in the growth media of perlite+cocopeat.

중증 두부 손상 환자의 예후 인자에 대한 임상 분석 : Clinical Prognostic Factors

송준석,하은주,이종수,이승재,박효일 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.2

A clinical analysis was carried out retrospectively with 54 cases of severe head injured patients(Glasgow Coma Scale score 3 to 8) in identify prognostic factors. Unawareness for over 1 month, abnormal pupillary reaction, abnormal motor response pattern, and diffuse head injury with basal cisternal compression prove to be the most reliable predictors. Individual predictions of outcome provide a powerful tool for assessing the relative efficacy of alternative treatments.

유도 전동기를 위한 자기 동조 퍼지 제어기 설계

전광호,하남수,박준열,김상윤 弘益大學校 科學技術硏究所 1998 科學技術硏究論文集 Vol.9 No.2

The conventional PI control, that are used in the control loop for outer speed of the induction motor, also has difficulty dealing with the dynamic speed tracking, parameter variation, and the load disturbance. As a result, the motion control system operates with a poor performance in the motor´s low speed range. In this paper, a novel speed control system that implements the fuzzy logic controller(FLC) is proposed. The proposed FLC used the speed error, its rate of change, and the drive current as three fuzzy variables. The real command output current is chosen by the defuzzification of the fuzzy output extracted from the fuzzy control rules. The flux and the torque of the induction motor are estimated using the dynamic model with an excellent dynamic response over a wide speed range and with the rotor flux field-oriented scheme of the decoupling characteristics. The performance of this control system is substantiated by computer simulations.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

급성충소돌기염의 임상 : 병리학적 고찰

양기화,조준필,하영천,한진우,정학재,손수창,이성희,황재훈,신철호 최신의학사 1989 最新醫學 Vol.32 No.4

신경회로망을 이용한 용접잔류응력 예측에 관한 연구

차용훈,김일수,김하식,이연신,김덕중,성백섭,서준열 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.6

In order to achieve effective prediction of residual stresses, the series experiment were carried out and the residual stress-es were measured using the backpropagation algorithm from the neural network and the sectional method. Using the experimental results, the optiomal control algorithms using a neural network should be developed in order to reduce the effect of the external disturbances on residual stresses during GMA welding processes. The results obtained from the comparison between the measured and calculated results, showed that the neural network based on backpropagation algorithm can be used in order to control weld quality. This system can not only help to under-stand the interaction between the process parameters and residual stress, but also, improve the quantity control for welded structures. The development of the system is goal in this study.