야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

핸드볼 페널티드로우 시 숙련자와 비숙련자 간의 시각적 변이 비교 분석

한재희,박영민,신선미,이준희,심윤식 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

The purpose of this study is to analyze the visual variation of skilled and unskilled people, and to obtain data necessary for skill improvement of effective handball penalty throw. An eye tracker was used to collect eye movements, concentration points, directions, and paths during penalty throws. The results are as follows: 1) For skilled players, the place where they threw and the place where their eyes were focused matched. 2) There is no difference in the presence or absence of eye contact with the goalkeeper.

Low doses of ionizing radiation suppress doxorubicin-induced senescence-like phenotypes by activation of ERK1/2 and suppression of p38 kinase in MCF7 human breast cancer cells

신재식,우상혁,이형찬,홍승우,유두현,홍석일,이왕재,이명석,진영우,안성관,진동훈,박인철 Sookmyung Women's University Research Institute of 2010 여성과 건강 Vol.6 No.1

Metallo-β-lactamase 생성 Pseudomonas aeruginosa 및 포도당 비발효그람음성간균의 검출방법에 관한 연구

신경섭,김원식,손재철,홍승복,최재운,형성민 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.2

연구목적: Metallo-β-lactamse (MBL)는 carbepenem를 포함하는 대부분의 β-lactam 항균제를 가수분해할 수 있으므로 MBL 생성균의 확산은 이들 균에 의한 감염의 치료에 큰 문제를 야기할 수 있다. 따라서 MBL 생성균에 의한 감염의 확산을 막기 위해 이들 균의 조기 검출이 필요하다. 저자들은 MBL 생성균을 검출할 수 있는 세 가지 방법을 PCR 방법과 비교하여 보았다. 재료 및 방법: Imipenem의 MIC가 8 μg/mL 이상인 50개의 포도당 비발효 그람음성 간균을 대상으로 EDTA-double disk synergy test (EDTA-DDS), Etest MBL, Hodge 변법을 시행하였으며 대조 검사로 IMP-1, VIM-1, VIM-2에 대한 PCR을 시행하였다. 결과: 총 50 균주 중 MBL 생성균은 Pseudomonas aeruginosa 1 균주, Alcaligenens xylosxidans 7 균주 등 8 균주(16%)가 검출되었다. 이들 균주는 모두 VIM-2 형이었으며, EDTA-DDS, Etest MBL은 PCR 방법과 100% 일치하였다. Hodge 변법은 8 MBL 생성균주 중 2 균주를 검출하지 못했다. 결론: 50 균주 중 8 균주가 MBL 생성균이었고 모두 VIM-2 형이었다. Etest MBL은 가격이 비싸 검사실에서는 EDTA-DDS가 적당할 것으로 사료된다. Purpose: Because metallo-β-lactamase (MBL) has activity to hydrolysls against most β-lactam drugs, dissemination of MBL producing bacteria may cause problems of treatment of infection by their microorganisms. Early detection or screening for MBLs will contribute to prevent further spread of resistance. Authors compared three MBL detection methods with PCR for MBLs. Materials and Methods: For 50 isolates of g1ucose nonfermentative gram negative bacilli with reduced susceptability against imipenem (MIC≥8 μg/mL), EDTA-double disk synergy (EDTA-DDS), Etest MBL and modified Hodge test were compared with PCR detection method for MBLs. Results: Among 50 isolates of glucose nonfermentative microorganisms, eight MBL producers including a Pseudomonas aeruginosa and 7 Alcaligenes xylosoxidans were detected. Those isolates were VIM-2 producer. The results of EDTA-DDS and Etest MBL completely agreed with PCR for MBL detection. Two isolates among eight MBL Producers were not detected in modified Hodge test. Conclusion: All of MBL producing bacteria were VIM-2 genotype. In conclusion, EDTA-DDS may be useful method for MBL detection in clinical laboratory due to high cost of Etest MBL strip.

Nortriptyline 제제의 생물학적 동등성에 관한 연구

신재국,차인준,장인진,정원석,김용식,박찬웅,신상구 大韓臨床藥理學會 1993 臨床藥理學會誌 Vol.1 No.1

입원한 입시 스트레스 증후군 환자의임상양상에 관한 정신의학적 연구

신광철,진태원,이영식,이재우,이재광,이길홍 중앙대부설한국의과학연구소 1991 한국의과학 Vol.23 No.3

播種期 및 育苗日數가 黃色種 담배의 初期生育 및 收量에 미치는 影響

申周植,盧載榮,裵吉寬,朴相一 충북대학교 엽연초연구소 1984 煙草硏究 Vol.11 No.-

This experiment was carried out to study the influence of different sowing time, seedling age (the degree of delayed setting) and seedlingbed materials on the growth and yield components of flue-cured tobacco. The variety applied was N.C. 2326, was sown on March 1,11,21 and 31. Those plants were transplanted on the seeding bed mixed humus with sand at the ratio of humus 9 : sand 1 and humus 3: sand 7, 25 days after sowing. Seedlings were grown for 40, 50, 60 and 70 days (from sowing to setting) on the seed bed and seedling bed, and set on the pots (1/5,000a) in the vinyl house. The results obtained were as forlows . 1.The amount of growth of seedlings increased by late sowing and delayed setting. 2.Until the time before the maximum growth stage after setting, stem heigth was larger in the plots of late sowing and delayed setting. After the middle part of maximum growth stage, the earner the sewing time was, the more remarkable the influence of seedling age on the stem elongation was and the larder the seedling age was, the more remarkable the influence of sowing time on the stem elongation was. 3.Stem diameter was large in the plot to late sowing until the early part of maximum growth stage but after the middle part of maximum growth stage the diameter was large in the plants sown at March 11 and March 21. 4.The number of leaves per plant increased by late sowing and delayed setting shown significant difference after maximum growth stage. 5.Late setting made the stem height high and number of leaves per plant more. The size of largest leaf was small in the plot of early sowing and large in the plot set after May 10. 6.It takes more days to reach a topping time from sowing and setting in the case of early sowing and early setting. 7.In early sowing plots, the leaf area of lugs and cutlers decreased by younger seedling age, and in late sowing plots, that decreased by older seedling age. The leaf area of leaf and tip at different treatments showed similar results, but in the plots sown at March 11 and 21, largest leaf was shown in the plot of 50- day seedlings. The area of green tip decreased by late seeding and delayed setting. As a result of theses the plant type showed sylindrical in the plot of early sowing and younger seedling age, and cone shape in the plot of late sewing and older seedling age. 8.The earlier the sowing time and the younger the seedling age were, the heavier the weight of unit leaf area of lugs and cutters, but there were little influences of different sowing time and seedling age on the weight of unit leaf area of leaf, tip and green tip. The percentage of dry matter showed similar tendency to the results of weight of unit leaf area. 9.Late sowing (March, 31) decreases the weight of a cured leaf. Weight of cured cutter was largest in the plots sowing March 1 and that of leaf tip and green tip was largest in the plots sowing March 11 and March 21. The weight of cured lugs was largest in 40 and 50-day seedlings, and that of tip and green tip was largest in 50-day seedlings. There were little differences of weight of a cutter and leaf among the treatments of different seedling age. 10.In 40- day seedlings, the area and weight of leaves per plant increased by late sowing, and in 70-day seedlings, those increased by early sowing. In 50 and 60-day seedlings, those were highest in the plots sown at March 11 and March 21. Largest weight and area of leaves per plant was shown in the plot set on May 10, and the plots set on April 10, and June 1 showed significantly low weight of loaves per plant. 11.Late sowing and older seedling age increased the leaf thickness of those leaves. Different sowing time and the seedling age did not influence on the leaf area contraction ratio and leaf thickness of leaf, tip and green tip. 12.There were significantly negative correlation between leaf area of lug and cutter and weight per unit leaf area, percentage of dry matter and leaf thickness of the lug and cutters, but no correlation between those characters of leaf, tip and green tip. Weight per unit leaf area correlated positively with percentage of dry matter and specific leaf weight in all stalk position. In the lug and cutter, weight per unit leaf area correlated positively with leaf thickness and negatively with leaf area contraction between weight per unit leaf area and leaf area contraction ratio. There were negative correlation between leaf thickness and leaf area contractions of lugs and cutters, and no correlation between those characters of leaf, tip and green tip. 13.There were not significant effects of seedling bed materials applied in this experiment on the growth after setting and yield components.

대형 화재로 인한 사상자의 손상 유형과 합병증 : 동인천 라이브호프 화재를 중심으로

신중호,김재광,염석란,신종환,민순식,임용수,양혁준,이근,황성연 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3

Background: High risks of fire alway exist for buildings in urban areas, especially those in downtown. Crowds, as well as more complex and larger structures, may cause more victims in the event of fire; therefore, emergency medical service plans must be established for such disastrous events. Methods: On the evening of October 30,1999, a fire broke out in downtown, Dong-Incheon Live-Hof restaurant; 56 people were killed and 76 were injured. Most of them were teenagers. We retrospectively reviewed the medical records of the victims, Results: 1) Among the 56 dead, 54 died from smoke inhalation, one from extensive burns, and one from sepsis during treatment. 2) Among the 76 injured, 70 patients suffered from smoke inhalation, 53 from burns, and 9 from several types of trauma (sprains, contusions, lacerations, abrasions, fractures, etc.). 3) Later complications were laryngeal edema, pulmonary edema, scar contracture, and hypoxic brain damage, and so forth. 4) Post traumatic stress syndrome was unexpectedly more prevalent in mildly to moderately injured survivors and witnesses than in seriously injured survivors. Conclusion: Many complications exist after a fire. Some may be resolved in time, but others may result in permanent sequelae. Early rescue, early triage, and early management during transport by emergency medical service (EMS) personnel can result in fewer complications and a lower mortality rate. Therefore, we propose the establishment of plans to be followed during various major disasters.

Low doses of ionizing radiation suppress doxorubicin-induced senescence-like phenotypes by activation of ERK1/2 and suppression of p38 kinase in MCF7 human breast cancer cells

신재식,우상혁,이형찬,홍승우,유두현,홍석일,이왕재,이명석,진영우,안성관,진동훈,박인철 Sookmyung Women's University Research Institute of 2010 여성과 건강 Vol.6 No.1

KB-509(Flutoprazepam)의 임상효과에 관한 연구

하재창,신홍식 최신의학사 1989 最新醫學 Vol.32 No.9