Photonic Crystals: Integration of Colloidal Photonic Crystals toward Miniaturized Spectrometers (Adv. Mater. 9/2010)

Kim, Shin-Hyun,Park, Hyo Sung,Choi, Jae Hoon,Shim, Jae Won,Yang, Seung-Man WILEY-VCH Verlag 2010 Advanced materials Vol.22 No.9

<B>Graphic Abstract</B> <P>The cover shows a schematic illustration of patterned colloidal photonic crystals with different bandgap positions. When an unknown light source impinges on the patterned photonic crystals, the light information can be identified from the reflection intensity profile of the constituent photonic crystals. The two optical microscopy images and background image display integrated photonic crystals with 20 different bandgaps spanning the entire visible range, and the SEM image shows the cross-section of the photonic crystal stripes, as reported by Shin-Hyun Kim, Seung-Man Yang, and co-workers on p. 946. <img src='wiley_img_2010/09359648-2010-22-9-ADMA201090022-content.gif' alt='wiley_img_2010/09359648-2010-22-9-ADMA201090022-content'> </P>

用寒遠寒과 用熱遠熱에 대한 考察 : 六元正紀大論에서

채영진,신창환,임현택,여성원,한성규,이재원,정헌영,금경수 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

Five elements motion and six kinds of natural factors influence not only human disease but also difference of medicine effect. Because the climate of summer is very hot, that is easy to increase the properties of hot medicines, a doctor must be careful to use it in summer. Also the climate of winter is very cold, that is easy to increase the properties of cold medicines, a doctor must be careful to use it in winter. But in the certain conditions to use diaphoretics or purgatives, in spite of that regulation a doctor can use them.

초등학교 수학영재, 과학영재, 일반 학생의 학습유형 및 교수방법 선호도 비교

이신동(Lee Shin Dong),원재권(Won Jae Gourn),김기명(Kim Ki Myoung) 한국영재교육학회 2007 영재와 영재교육 Vol.6 No.2

본 연구는 Kolb의 4가지 학습유형에 따라 초등학교 수학영재, 과학영재, 일반 학생의 학습유형을 비교해 보고, 학습유형에 따라 교수방법 선호도가 어떻게 달라지는지 확인하기 위한 것이다. 이를 위해 지역교육청 2곳의 영재교육원 초등학교 수학ㆍ과학영재 학생 각60명, 일반 학생은 초등학교 2곳의 6학년 120명 총 240명을 연구 대상으로 하였으며, 이들의 학습유형검사ㆍ교수방법선호도 검사의 자료를 수집ㆍ분석하였다. 검사도구로는 Kolb(1999)의 학습유형검사(LSI), Renzulli, Rizza, & Smith(2002)의 교수방법 선호도 측정 검사지를 활용하였다. 본 연구의 결과 수학영재 학생과 과학영재학생의 학습유형은 차이가 없었으나 영재학생과 일반학생의 학습유형에는 차이가 있었으며, 동화적 학습자 유형을 제외한 발산적 학습자, 수렴적 학습자, 조절적 학습자 유형은 고유하게 선호하는 교수방법들을 가지고 있었다. 또한 수학영재 학생과 일반학생은 학습유형에 따른 교수방법 선호도에 차이가 없었으나, 과학영재 학생은 학습유형에 따fms 교수방법 선호도가 다르게 나타났다. 이런 결과는 영재학생과 일반학생의 학습유형이 서로 다르고 그에 따른 교수방법도 다르다는 것을 나타낸다. 따라서 교실수업을 담당하는 교사들은 학생들의 학습유형에 맞는 교수방법을 제공하여 교수적합성을 달성함과 동시에 교수 효과를 극대화하기 위해서 각각의 학습유형과 교수방법에 대한 충분한 이해가 선행되어야 할 것이다. The purpose of this study is to compare the learning styles of the mathematics gifted, the science gifted, and general students at elementary schools by Kolb"s four learning styles, and ascertain how the preference of instructional methods become different by learning style. To achieve the purpose in this study, the four propositions were set as follows: First, what differences exist among the mathematics gifted, the science gifted and general students in terms of learning style? Second, what differences exist in terms of the preference of instructional methods by learning style among the mathematics gifted, the science gifted, and general students? To solve the abovementioned propositions, this study targeted 60 elementary school-level mathematics gifted students, 60 science gifted students at gifted students education institutes, and 120 six graders at Elementary School: this study targeted a total of 240 students. For the learning style test used in this study, ""Learning Style Inventory (LSI),"" which originally presented by Kolb in 1976, but was revised anew in 1999, and was translated by Lee, Shin-dong (2005), was used. As a test to measure the preference of instructional methods, ""Measure of Student Preference for Instructional Techniques,"" developed by Renzulli, Rizza, and Smith (2002), and translated by Lee Shin-dong (2005) was used. The confidence levels of the tests were good, respectively. The analysis of the collected test responses was tested through a confidence analysis, technical statistics, MANOVA, and Sheffe test was used for follow up test. The SPSS 12.0 Program was used for the analysis. The analytical results of the collected data are presented as follows: Firstly, there was no difference in the learning style of the mathematics gifted and the science gifted, but there was difference in the learning style of the gifted and general students. Secondly, it was identified that divergent learners, convergent learners, regulated learners, except for assimilative learners, had their preferred instructional methods. Thirdly, there was no difference in the preference of instructional methods by learning style and gender between the mathematics gifted and general students. The science gifted students had different preference of instructional methods by learning style, but they did not show any difference on the preference of instructional methods by gender. In conclusion, the divergent learners and convergent learners are judged to be more active in learning activities and have higher learning motivation. Teachers taking charge of classroom teaching should provide instructional methods in line with such learning styles so as to achieve the adequacy of instruction, and draw maximum instructional effects. Those teachers also need to pay more attention to enhancing learning motivation of the relatively passive regulated learners and assimilative learners.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

Metallo-β-lactamase 생성 Pseudomonas aeruginosa 및 포도당 비발효그람음성간균의 검출방법에 관한 연구

신경섭,김원식,손재철,홍승복,최재운,형성민 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.2

연구목적: Metallo-β-lactamse (MBL)는 carbepenem를 포함하는 대부분의 β-lactam 항균제를 가수분해할 수 있으므로 MBL 생성균의 확산은 이들 균에 의한 감염의 치료에 큰 문제를 야기할 수 있다. 따라서 MBL 생성균에 의한 감염의 확산을 막기 위해 이들 균의 조기 검출이 필요하다. 저자들은 MBL 생성균을 검출할 수 있는 세 가지 방법을 PCR 방법과 비교하여 보았다. 재료 및 방법: Imipenem의 MIC가 8 μg/mL 이상인 50개의 포도당 비발효 그람음성 간균을 대상으로 EDTA-double disk synergy test (EDTA-DDS), Etest MBL, Hodge 변법을 시행하였으며 대조 검사로 IMP-1, VIM-1, VIM-2에 대한 PCR을 시행하였다. 결과: 총 50 균주 중 MBL 생성균은 Pseudomonas aeruginosa 1 균주, Alcaligenens xylosxidans 7 균주 등 8 균주(16%)가 검출되었다. 이들 균주는 모두 VIM-2 형이었으며, EDTA-DDS, Etest MBL은 PCR 방법과 100% 일치하였다. Hodge 변법은 8 MBL 생성균주 중 2 균주를 검출하지 못했다. 결론: 50 균주 중 8 균주가 MBL 생성균이었고 모두 VIM-2 형이었다. Etest MBL은 가격이 비싸 검사실에서는 EDTA-DDS가 적당할 것으로 사료된다. Purpose: Because metallo-β-lactamase (MBL) has activity to hydrolysls against most β-lactam drugs, dissemination of MBL producing bacteria may cause problems of treatment of infection by their microorganisms. Early detection or screening for MBLs will contribute to prevent further spread of resistance. Authors compared three MBL detection methods with PCR for MBLs. Materials and Methods: For 50 isolates of g1ucose nonfermentative gram negative bacilli with reduced susceptability against imipenem (MIC≥8 μg/mL), EDTA-double disk synergy (EDTA-DDS), Etest MBL and modified Hodge test were compared with PCR detection method for MBLs. Results: Among 50 isolates of glucose nonfermentative microorganisms, eight MBL producers including a Pseudomonas aeruginosa and 7 Alcaligenes xylosoxidans were detected. Those isolates were VIM-2 producer. The results of EDTA-DDS and Etest MBL completely agreed with PCR for MBL detection. Two isolates among eight MBL Producers were not detected in modified Hodge test. Conclusion: All of MBL producing bacteria were VIM-2 genotype. In conclusion, EDTA-DDS may be useful method for MBL detection in clinical laboratory due to high cost of Etest MBL strip.

성인에서 지역 사회 획득 폐렴 (원외 폐렴) 치료를 위한 항생제의 사용원칙

신종욱,김재열,박인원,최병휘 중앙대학교 의과대학 의과학연구소 2003 中央醫大誌 Vol.28 No.2-3

각국에서 제시되고 있는 여러 가지 원외 폐렴의 치료 지침은 일부 차이가 있지만 다음과 같은 공통적인 원칙을 정할 수 있다. 1. 모든 입원 환자는 병원도착 8시간 이내에 주사용 항생제를 투여하여야 한다. 2. 치료의 목표가 되는 원인균에는 비전형적 병원균과 폐렴구균을 반드시 포함하는 항생제를 선택하여야 한다. 3. Macrolide 단독 치료는 심폐질환이 없고 약제내성 폐렴구균, 그람음성간균, 흡인의 위험이 없는 원외 폐렴에 시도해볼 수 있으나 작금 국내의 항생제 내성률을 고려하면 실패의 위험이 있다. 4. 약제내성 폐렴구균 (Drug-resistant Streptococcus pneumoniae; DRSP), 그람음성간균에 대한 위험 인자가 있는 외래 환자, 입원 원외 폐렴 환자에 대한 항생제로는 β-lactam/macrolide 병합요법이나 폐렴구균에 항균력이 강한 fluoroquinolone 단독 투여가 추천되면 동일한 효과를 기대할 수 있다. 5. DRSP의 임상적 위험 인자가 있는 원외 폐렴 환자의 외래 치료를 위해서는 β-lactam/macrolide 병합요법이나 폐렴구균에 항균력이 강한 fluoroquinolone 단독 투여가 추천되는데, 가능한 β-lactam 항생제로는 oral cefpodoxime, cefuroxime, high-dose amoxicillin, amoxicillin/calvuanate, pareneteral ceftriaxone followed by oral cefpodoxime 등이 포함된다. 6. DRSP위험 입원 환자에 대해서는 폐렴구균에 항균력이 있는 guinolone의 정맥 투여 또는 특정 β-lactam과 macrolide의 병합요법이 추천된다. 이 때 가능한 β-lactam 항생제로는 cefotaxime, ceftriaxone, ampicillin/sulbactam, high-dose ampicillin이다. 7. 항녹농균 항생제는 녹농균 감염의 위험이 확인된 중증의 원외 폐렴 환자에게만 제한적으로 투여되어야 한다. 항녹농균성 β-lactam은 이러한 위험 인자를 가진 환자에게만 선택적으로 경험 치료로서 투여하여야 한다. 8. Vancomycin은 중증의 원외 폐렴 환자이거나 수막염이 동반된 원외 폐렴일 경우에만 경험적 치료에 선택되어야 한다. 9. 폐렴구균에 항균력이 있는 quinolone제재들은 체외 감수성 검사에서 서로 다른 항폐렴 구균능을 갖고 잇다. 최소로부터 최고 순으로 나열하면 levofloxacin, gatifloxacin, moxifloxacin 순서이며 가장 항균력이 강한 약제가 내성을 유발할 가능성이 가장 낮다. 10. 사망률을 증가시킬 것으로 예상되는 임상적 의미를 갖는 폐렴구균의 penicillin 내성은 penicillin MIC가 4g/㎖ 이상일 때이다. Community-Acquired Pneumonia (CAP) is still one of the leading causes of major morbidity and mortality of infectious diseases in immunocompetent hosts. Although antibiotics are mainstay of treatment for CAP, a definite guideline remains to be uncertain. This uncertainty currently forces physician out to make therapeutic challenge with modest danger. So we intend to prepare a guideline for antibiotic usage for CAP. Most causative etiologies contain Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, Chlamydia pneurnoniae, Legionella pneumophila. Antibiotics should be administered to cover all these organisms when a definitive etiologic microorganism are not determined. Except for aspiration pneumonia, one pneumonia usually has one causative agent. Drug-resistant Streptococcus pneumoniae and Haemophilus influenzae should be considered for antibiotic choice. Severity of CAP depends on cardiopulmonary physiologic status, age and comorbid conditions. In this regard, fluoroquinolones and β -lactam antibiotics and macrolides can be successfully administered for the treatment of CAP.

고주파수대역에 적용되는 Fe-( BN, Si₃N₄)박막의 미세구조와 자기적특성에 관한 연구

申東勳,張勝彦,李宰源,南勝義 弘益大學校 科學技術硏究所 1997 科學技術硏究論文集 Vol.8 No.-

We have investigated the magnetic properties of FeBN thin films deposited by using RF magnetron sputtering and Fe-BN composite target. It was investigated that the area fraction of BN chips on the Fe target and partial pressure of nitrogen was the main factors influencing the soft magnetic properties and resistivity of FeBN thin film. The low addition of N₂increases significantly the soft magnetic properties and electrical resistivity. The good soft magnetic properties are obtained at N₂partial pressure of 5%, but futher increase in N₂ partial pressure degrade the soft magnetic properties due to formation of nitrides such as Fe₄N, Fe₂∼₃N. In a sputtering process, as the area fraction of BN increases, FeBN thin films fabricated at the area fraction of 0.25 exhibt soft magnetic properties (Bs∼17kG, Hc∼10e, μ∼1000).

Urapidil, Labetalol의 투여가 기관내 삽관시 심혈관계에 미치는 영향

신용섭,윤석화,손수창,이원형,이정은,황원재,김만수,김영주,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

We have examined the comparative efficacy of small doses of intravenous urapidil and labetalol in blunting hemodynamic response to endotracheal intubation and surgical incision in 30 patients without cardiovascular diseases. After intravenous urapidil 0.2 mg/kg or labetalol 0.2 mg/kg anesthesia was induced with thiopental 5mg/kg. Endotracheal intubation was facilitated by vecuronium 0.15 mg/kg with priming principle and anesthesia was maintained with enflurane and nitrous oxide in oxygen. Systolic, diastolic and mean arterial pressure and heart rate were measured before administration of the drugs, 5 minute after administration, just prior to endotracheal intubation and 1, 3, 5, 10 minute after intubatin. Also the peak blood pressures and heart rate within 10 minutes after surgical incision were measured. Endotracheal intubation and surgical stimulation were associated with significant increases in blood pressures and heart rate in both urapidil and labetalol group. Comparison of the changes in systolic, diastolic, and mean artrial pressures and heart rate between urapidil and labetalol group showed no significant difference except peak systolic pressure after surgical incision. It is concluded that the pressor response to endotracheal intubation and surgical stimulation are not influenced significantly by urapidil 0.2 mg/kg or labetalol 0.2 mg/kg. However, urapidil and labetalol preloading may be similarly effective in the blunting of the increases in blood pressures with larger doses of the durgs during anesthetic induction.

입원한 입시 스트레스 증후군 환자의임상양상에 관한 정신의학적 연구

신광철,진태원,이영식,이재우,이재광,이길홍 중앙대부설한국의과학연구소 1991 한국의과학 Vol.23 No.3

급성 림프구성 백혈병 환자에서 발생한 침습성 국균 심내막염 2예

신성철,백경란,정재홍,송봉근,김동희,전경만,채제욱,손준성,정숙인,오원섭,송재훈 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

국균은 호흡기를 통해 유입되며 심한 면역기능저하 환자에서 기회감염을 일으키는 진균이며 주로 혈관을 따라 폐를 침범하고 심장과 골침범은 매우 드문 것으로 알려져 있다. 저자들은 급성 림프구성 백혈병 환자에서 발생한 침습성 국균 심내막염을 2예을 경험하였다. 19세 남자환자로 동종 조혈모세포이식 후 발생한 고열과 요통의 원인으로 감염성 심내막염 진단하에 수술결과 국균에 의한 감염으로 확증되어 수술적 절제술과 liposomal amphotericin B로 치료하였으나 국균 심내막염의 재발과 국균 척추염의 악화, 뇌 출혈로 사망하였다. 23세 남자환자로 관해요법 후 발생한 고열과 요통의 원인으로 국균 심내막염과 국균 척추염 진단하에 수술적 절제술과 amphotericin B로 치료하여 1년 2개월 동안 국균 심내막염의 재발은 없었으나 지속적인 백혈병의 재발과 국균 척추염의 악화, 침습성 폐 국균증으로 사망하였다. Although Aspergillus endocarditis has rarely been reported, it can cause fatal complications in hematologic malignancy patients and allogeneic stem cell transplant recipients. We experienced two cases of aspergillus endocarditis developed in acute lymphoblastic leukemia patients. Case; A 19-year-old patient developed Aspergillus endocarditis after allogenic hemopoietic stem cell transplantation. He was treated with surgical intervention and liposomal amphotericin B. He died of recurred Aspergillus endocarditis and cerebral hemorrhage probably related with aspergillosis of central nervous system. Case 2; A 23-year-old patient developed invasive Aspergillus endocarditis after induction chemotherapy. Aspergillus endocarditis was successfully treated by surgical intervention and amphotericin B. He died of refractory neutropenic fever and sepsis after the third relapse of leukemia and repetitive chemotherapy. He probably had invasive pulmonary aspergillosis without evidence of endocarditis recurrence. Because the mortality of Aspergillus endocarditis is very high, early diagnosis and surgical intervention are very important for better outcome.