대황황련해독탕의 사염화탄소 유발 간장해 보호효과 미치 급성독성

김영석,정은아,장종철,양형길,김남재,조기호,배형섭,이경섭,김동현 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2002 東西醫學硏究所 論文集 Vol.2002 No.-

ABSTRACT - This study was performed to evaluate hepatoprotective effect of daewhang-whangryunhaedok-Tang(DWT) on liver injured rats induced by CCI_4 and the acute oral toxicity of it in mice. The activities of serum transaminase(ALT/AST), alkaline phosphatase(ALP) and lactic dehydrogenase(LDH), the levels of serum total cholesterol(TC) and triglyceride(TG), change of liver enlargement, and inhibitory activities of lipid perotidation, catalase and glutathione-S-transfrease(GST) in liver microsome were determined in hepatotoxic rats induced by CCI_4. DWT was significantly reduced the serum ALT, AST, ALP, LDH. TC and TG lecels. And, the increase of lipid peroxidation, decrease of catalase and GST activities in the liver microsome of CCI_4-intoxicated rat were significantly improved by the treatment of DWT. Male and female mice were administered maximum dosages of 5.000 mg/kg b.w. of DWT. After single oral administration of DWT to mice, we observed them daily for 2 weeks.DWT did not induce any toxic signs in the mortalitie, clinical signs, body weight changes, and gross necropsy finfings of mice. Based in these results. It is concluded that DWT may have the hepatoprotective effect on CCI_4 induced hepatotoxicity in rats. Also. DWT may have no side effect and its LD_50 value may be over 5.000mg/kg b.w. in mice.

대황황련해독탕의 항고지혈증 작용

김영석,정은아,장종철,양형길,김남재,조기호,배형섭,이경섭,김동현 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2001 No.-

Whangryunhaedok-Tang (WT) is formulated with Coptidis Rhizoma, Phellodendri Cortex, Scutellariae Radix and Gardeniae Fructus, and Daewhang-whangryunhaedok-Tang (DWT) is made by the combination of Rhei Rhizoma, a wellknown anticostipation drug in WT. Therefore, DWT has been evaluated for antihyperlipidemic effects on experimental hyperlipidemic rats and mice induced by corn oil and high cholesterol-diet. Oral administration of DWT significantly inhibited the increase of serum triglyceride and LDL-cholesterol levels, and the decrease of serum HDL-cholesterol levels in hyperlipidemic rats induced by corn oil. Also, oral administration of DWT significantly prevented the increase of serum total cholesterol, triglyceride and LDL-cholesterol, and liver total cholesterol and triglyceride in 1% cholesterol-diet fed mice. These results suggest that DWT is effective for the treatment of hyperlipidemia.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

중풍환자(中風患者)의 혈관성치매에 대한 임상적(臨床的) 관찰(觀察)

김원찬,김영석,문상관,고창남,조기호,배영섭,이경섭,박정미,Kim Won-Chan,Kim Young-Suk,Moon Sang-Kwan,Ko Chang-Nam,Cho Ki-Ho,Bae Hyung-Sup,Lee Kyung-Sup,Park Jung-Mi 대한한방내과학회 1998 大韓韓方內科學會誌 Vol.19 No.2

Background : Vascular dementia occurs mainly due to cerebral vascular disease. So we performed this clinical study to investigate the incidence and characteristics of vascular dementia in stroke patients. Methods : This study was performed on the patients hospitalized from April 1, 1998 to August 31, 1998 at the department of circulatory internal medicine, hospital of Oriental medicine, Kyung-Hee University, and diagnosed cerebral infarction or hemorrhage by Brain CT or MRI. we devided the patients into two groups; vascular dementia group and non dementia group according to MMSE-K(Mini Mental State Examination Korean version), Hasegawa dementia scale. Patients were diagnosed dementia using DSM-IV. We compared general characteristics, stoke types and laboratory findings between the two groups and investigated the correlationship between MMSE-K and Hasegawa dementia scale. Results : Results showed that the incidence of vascular dementia was about 27.8% in stroke patients. The greater number of subjects with dementia were women in the lower educational classes and had lower MBI(Moderfied Bathel Index) scores. Vascular dementia were more common in patients with large brain lesion size($>20cm^3$). There was a positive correlationship between Hasegawa scores and MMSE-K.

딤플을 적용한 평판에 대한 항력 감소 연구

백부근(Bu-Geun Paik),편영식(Young-Sik Pyun),김준형(Jun-Hyung Kim),김경열(Kyung-Youl Kim),김기섭(Kim1 ?Ki-Sup),정철민(Chul-Min Jung),김찬기(Chan-Ki Kim) 대한조선학회 2012 大韓造船學會 論文集 Vol.49 No.4

Education Policy and Industrial Development : The Cases of Korea and Mexico

Kim,Chong-Sup,Hong,Min-Kyung 서울대학교 국제학연구소 2010 Journal of International and Area Studies Vol.17 No.2

After many scholars' studies, it has been suggested that among several facts of economic growth, Korea's relatively intensive investment in education made its fast economic growth possible. This study started from the question of whether large education expenditure automatically leads to a fast economic growth. We suggest that the expenditure must be allocated to the education level that is in accordance with the industrial policy, which in turn must consist with the country's economic development stage. In Korea, the education sector supplied workers with adequate level of education that was required in each stage of development, whereas in Mexico, the supply of workers by education level was mismatched with the demand for labor derived from the industrial structure at each development stage. We conclude that not only the size of the expenditure but also its efficient use is important to guarantee the positive effects of education expenditure on economic growth.

태권도 경기 심판 판정 개선에 관한 연구

김경지,박현섭 경희대학교 체육대학 한국체육과학연구소 2004 體育學論文集 Vol.32 No.-

It is the purpose of this research that finds on solution, one of the efforts to seek for the improvement and secure the base about improving the judgement of Taekwondo, to disentangle a complicated matter which remains in a sports fields, with a method which find out the referees'(the one) and coaches'(the other) understanding and opinion about those subjects above mentioned. The target of this study is the permanent referees, 65 persons, who participated in the national team elimination match and the outstanding coaches, 65, who already have many players taken part in the game. In advance, I made a questionnaire with the help from existing studies, asked a professor of the Taekwondo department, the head of referee committee, a coach of the national team, and an officer of the associates to examine, modified and wrote it down. The confidence of it recorded 99.2%. I took statistics respectively on percentage, the maximum frequency, average, and so on Chi square and T-test are used for the analysis of the differences between the two groups. After operating these, I get some conclusions. 1) There is a big difference between the two groups' on the accuracy and justice that Taekwondo match has. 2) Referees see present judgement getting better, coaches don't. 3) The two groups(the one and the other) don't trust each other so that each members can get stresses at the worst. 4) To develope the quality of the judgement in match, the think best to reduce a trend of mutual distrust and make their performance higher. On the contrary, the others assists that the referees competence and educational system should be in priority. 5) According to the two, they all take the misjudgement for granted when winning and leading take place. 6) Also the big difference between the two groups' opinion occurs in the winning and leading. 7) The one doesn't think that the import of the graded score system has an impact on the improvement of the judgement but the other does. 8) The one regards existing criteria in judging "leading" as good but the other doesn't. 9) The coaches think of a warning judgement and a penalty count system as being used for the unfair judgement but the referees are in the opposite. 10) the referees think that the import of the supervisor system doesn't have an effect on the correctness and fairness in the match but the coaches don't think so.

저산소증이 백서간장내 Glycogen양과 Phosphoenolpyruvate Carboxykinase활성에 미치는 영향

김경섭,이기영,김건홍,박병옥 공군본부 의무감실 1991 항공의학 Vol.39 No.1-2

정부혁신의 길 : 레드테이프에서 결과중심으로 From Red Tape to Result-Oriented Perforrnance

김병섭,박광국,조경호,최외출 영남대학교 지역발전연구소 1997 새마을지역개발연구 Vol.21 No.-

After the adoption of local autonomy, local governments have tried to enhance the local competitive power by eliminating the bureaucratic dysfunction, such as red tapes, formalism, and so on. This study, however, investigates to find out the eufunction as well as the malfunction of red tape. With the research hypotheses which are drawn from the literature review, the survey was conducted with the sample of 1,023 subjects. Our analysis shows three interesting findings. First, the level of fomalization and red tape is higher in the public rather than the private sector. Second, the level of goal ambiguity which is highly correlated with that of formalization is higher in government organizations rather than private ones. Finally, the level of both organizational commitment and organizational loyalty is higher in the public sector, compared with the private sector. Therefore, these findings suggest that the chief executive of government organization should pay more attention to enhance the morale of government employees. Otherwise, the bureaucratic pathology which decreases the organizational productivity may be prevalent in the public sector.

U-서비스 이용에 영향을 미치는 유비쿼터스 특성에 관한 실증연구

김경호,장기섭 김천과학대학 2007 김천과학대학 논문집 Vol.33 No.-

Ubiquitous computing is enhancing computer use by making many computers available throughout the physical environment, but making them effectively invisible to the user. To facilitate the successful adoption and diffusion of ubiquitous computing, it is necessary to figure out the factors affecting the use of U-service. Though the research related to ubiquitous computing has been vigorously conducted from the aspect of system and service provider, there have been very few studies that focus on the user's perspective. Therefore, this study attempts to figure out major factors which are dedicated to the development of ubiquitous computing and u-service, and that ultimately influence the u-business outcome. This study derived the factors that characterize u-service, such as ubiquity, contextual offer, reliability, invisibility, and confidentiality, which are then combined in the TAM model and carry out the path analysis. The research findings indicate that ubiquity affects both the perceived usefulness and perceived ease of use. The reliability and confidentiality were found to affect the perceived usefulness, whereas the contextual offer and invisibility turned out to influence the perceived ease of use. Finally, the relationship among the perceived usefulness, perceived ease of use, and the attitude toward using are identical with the previous research findings related to the technology acceptance model (TAM).