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Molecular Cloning and Expression of Inositol 1,4,5 - Triphosphate 3 Kinase
Moon, Kyung Ho,Kim, Jae Won,Rhee, Sue Goo,KIM, HA KUN,Lee, Sang Yeol,Choi, Kwan Yong,Chung, Hong Keun,Sin, Sang Soo 한국유전학회 1990 Genes & Genomics Vol.12 No.4
Department of Life Science, Pohang Institute of Science and Technology, Pohang, Korea, *^Department of Biochemistry, Kyongsang National University, Chinju, Korea, (**)^Department of Biochemistry, Kyongsung University, Pusan, Korea, (++)^Department of Biochemistry, College of Medicine, Seoul National University, Seoul, Korea, +^Laboratory of Biochemistry, NHLBI, N.I.H., Bethesda, MD 20892, U.S.A.
Design and Implementation of the RF Systems for Bi-directional Wireless Capsule Endoscopes
Moon, Yeon-Kwan,Lee, Jyung-Hyun,Park, Hee-Joon,Lee, Ju-Gab,Ryu, Jae-Jong,Lee, Wu-Seong,Woo, Sang-Hyo,Won, Chul-Ho,Cho, Jin-Ho,Choi, Hyun-Chul Korea Multimedia Society 2006 멀티미디어학회논문지 Vol.9 No.12
This paper explains that the RF systems for hi-directional wireless capsule endoscopes were designed and implemented. The designed RF systems for a capsule endoscope can transmit the images of intestines from the inside to the outside of a body and the behavior of the capsules can be controlled by an external controller simultaneously. The hi-directional wireless capsule endoscope consists of a CMOS image sensor, FPGA, LED, battery, DC to DC Converter, transmitter, receiver, and antennas. The transmitter and receiver which were used in the hi-directional capsule endoscope, were designed and fabricated with $10mm(diameter){\times}3.2mm(thickness)$ dimensions taking into the MPE, power consumption, system size, signal to noise ratio and modulation method. The RF systems designed and implemented for the hi-directional wireless capsule endoscopes system were verified by in-vivo experiments. As a result, the RF systems for the hi-directional wireless capsule endoscopes satisfied the design specifications.
Application of Hot Start PCR Method in PCR-based Preimplantation Genetic Diagnosis
Sung Ah Kim,Moon Joo Kang,Hee Sun Kim,Sun Kyung Oh,Seung-yup Ku,Young Min Choi,Jong Kwan Jun,Shin Yong Moon 대한의학유전학회 2012 대한의학유전학회지 Vol.9 No.1
Purpose: To determine a method to improve the efficacy and accuracy of preimplantation genetic diagnosis (PGD)-polymerase chain reaction (PCR), we compared hot start PCR and conventional multiplex nested PCR. Materials and Methods: This study was performed with single lymphocyte isolated from whole blood samples that were obtained from two couples with osteogenesis imperfecta (OI). We proceeded with conventional multiplex nested PCR and hot start PCR in which essential reaction components were physically removed, and we compared the amplification rate, allele dropout rate and nonspecific products. Afterward, we used selective method for PGD. Results: In the two couples, the respective amplification rate were 93.5% and 80.0% using conventional multiplex nested PCR and 95.5% and 92.0% using hot start PCR. The respective mean allele dropout rates for the two couples were 42.0% and 14.0% with conventional multiplex nested PCR and 36.0% and 6.0% with hot start PCR. Conclusion: The results demonstrate that the hot start PCR procedure provides higher amplification rates and lower allele dropout rate than the conventional method and that it decreased the nonspecific band in multiplex nested PCR. The hot start method is more efficient for analyzing a single blastomere in clinical PGD.
Clinical outcome of high-dose-rate interstitial brachytherapy in patients with oral cavity cancer
Sung Uk Lee,MD,Kwan Ho Cho,MD,Sung Ho Moon,MD,Sung Weon Choi,MD,Sung Uk Lee,MD,Kwan Ho Cho,MD,Sung Ho Moon,MD,Sung Weon Choi,MD 대한방사선종양학회 2014 Radiation Oncology Journal Vol.32 No.4
Purpose: To evaluate the clinical outcome of high-dose-rate (HDR) interstitial brachytherapy (IBT) in patients with oral cavity cancer. Materials and Methods: Sixteen patients with oral cavity cancer treated with HDR remote-control afterloading brachytherapy using 192Ir between 2001 and 2013 were analyzed retrospectively. Brachytherapy was administered in 11 patients as the primary treatment and in five patients as salvage treatment for recurrence after the initial surgery. In 12 patients, external beam radiotherapy (50–55 Gy/25 fractions) was combined with IBT of 21 Gy/7 fractions. In addition, IBT was administered as the sole treatment in three patients with a total dose of 50 Gy/10 fractions and as postoperative adjuvant treatment in one patient with a total of 35 Gy/7 fractions. Results: The 5-year overall survival of the entire group was 70%. The actuarial local control rate after 3 years was 84%. All five recurrent cases after initial surgery were successfully salvaged using IBT ± external beam radiotherapy. Two patients developed local recurrence at 3 and 5 months, respectively, after IBT. The acute complications were acceptable (≤grade 2). Three patients developed major late complications, such as radio-osteonecrosis, in which one patient was treated by conservative therapy and two required surgical intervention. Conclusion: HDR IBT for oral cavity cancer was effective and acceptable in diverse clinical settings, such as in the cases of primary or salvage treatment.
Stochastic Integrated Generation and Transmission Planning Incorporating Electric Vehicle Deployment
Moon, Guk-Hyun,Kong, Seong-Bae,Joo, Sung-Kwan,Ryu, Heon-Su,Kim, Tae-Hoon The Korean Institute of Electrical Engineers 2013 Journal of Electrical Engineering & Technology Vol.8 No.1
The power industry is currently facing many challenges, due to the new environment created by the introduction of smart grid technologies. In particular, the large-scale deployment of electric vehicles (EVs) may have a significant impact on demand for electricity and, thereby, influence generation and transmission system planning. However, it is difficult to deal with uncertainties in EV charging loads using deterministic planning methods. This paper presents a two-stage stochastic decomposition method with Latin-hyper rectangle sampling (LHRS) to solve the integrated generation and transmission planning problem incorporating EV deployment. The probabilistic distribution of EV charging loads is estimated by Latin-hyper rectangle sampling (LHRS) to enhance the computational performance of the proposed method. Numerical results are presented to show the effectiveness of the proposed method.