서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

여자 리듬체조의 변천과정

이필영,최정현 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.1

It is important to investigate various gymnastics and dances that have influenced the origin of rhythmic sportive gymnastics in order to understand its cultural values and the importance of feminine sports. Therefore, the purposes of this study are to inquire into the backgrounds and to clarify the process of changes in rhythmic sportive gymnastics from its origins to the present. Rhythmic sportive gymnastics can be defined as a sport in which one expresses oneself in feminine beauty and rhythmic motion. Formed under the influence of dances and gymnastics such as basic gesture of ballet, free gymnastics, water polo gymnastics, expressive gymnastics, artistic gymnastics, etc., rhythmic sportive gymnastics has developed into a sport entry. The World Tournament has been held every two year since the rhythmic sportive gymnastics firstly appeared as a sport entry at the first World Tournament in Budapest in 1963. It was officially adopted as a sport entry in the 1984 Los Angeles Olympics. Since then, its rules have become more elaborate and have undergone some changes. In the 1980s, the rules of the game were firmly set and its techniques significantly improved as it was rapidly settled as a sport entry. As a result, in 1990s, the focus of the rules was shifted to technical skills from its original feminine beauty and internal expression. For these reasons, feminine beauty, the power of expression, creativity and inner beauty, which are the essence of rhythmic sportive gymnastics, have gradually been disappearing.

국어과 협동 학습의 의미와 방법

이재승,정필우 청람어문교육학회 2003 청람어문교육 Vol.27 No.-

이 글은 국어과 협동 학습의 중요성과 구체적인 방법을 다루고 있다. 협동 학습은 한 마디로 일정한 구성원들이 공동의 학습 목표를 설정하고 그 목표에 도달하기 위해 동등한 입장에서 책무를 가지고 문제를 해결해 나감으로써 구성원 모두에게 유익한 결과를 산출해 내고 결과에 대해 공동의 평가를 강조하는 학습 형태이다. 이렇게 협동 학습은 공동의 목표를 갖는다는 점, 구성원 모두가 동등한 입장이라는 점, 개인의 책무성이 강조된다는 점, 모두에게 유익한 결과를 산출하고자 한다는 점, 결과에 대해 공동으로 책임을 진다는 점 등에서 일반적인 학습 형태와는 구별된다. 이 글에서는 국어과에서 협동 학습법의 뜻과 그 중요성을 다루었다. 그런 다음 국어과 협동 학습법을 적용할 때 유의해야 할 원리를 제시했다. 이는 학교 현장에서 협동 학습을 적용하는 데 하나의원리가 될 수 있을 것이다. 이어 국어과의 협동 학습법의 유형으로 배분 학습법, 상호 교수법 등을 제시했다. 그런 다음 각 협동 학습법을 적용할 때의 지도 절차를 살펴보았다. 그리고 협동 학습법의 적용에서는 교수 학습 과정안을 제시함으로써 협동 학습법의 적용 모습을 그려보는 데 도움이 될 수 있게 했다. Korean Language Learning can be achieved by the interaction of the Language among the students. Just as Vygotsky pointed out, the importance of 'social language' and 'role of adult and peer', Korean learning process can be done by the talking with the able student or a teacher, and by the established scaffolding which they communicate between little master and student, between a teacher and students. Accordingly, Cooperative Learning makes students play active roles in their Korean Language Learning.. Because one of the traits of Cooperative Learning is that the member of the group are from heterogeneous groups, Cooperative Learning evokes language interaction actively. 'Teaching According to students level' which the Seventh Korean Language curriculum point, aims individual teaching on the ground of the homogeneous traits of the student. But the social interaction of language which can be active among the heterogeneous groups will be diminished if we devide the student into able and poor group.

공기총 납탄의 비교 및 강선흔에 대한 연구

이정필,홍성욱,박성우 內務部 國立科學搜査硏究所 1996 國立 科學 搜査 硏究所 年報 Vol.28 No.-

신체관과 건강관의 관계 규명

이필영,최정현 龍仁大學校 體育科學硏究所 2003 體育科學硏究論叢 Vol.13 No.2

In modem society, health means a balanced state of body and mind, and a state of living without being given any threats of accidents in a desirable environment. It is the most important factor in determining the quality of life. Health is defined in various ways in different times and situations. Most of the cases, views on body are directly projected in views on health. The purpose of this study is to investigate different views on health based on the assumption that views on body and health will actually influence the health of contemporary people. For this purpose, relationships between views on body and on health which were closely examined through inquiring various documents and research articles on health. Body can be said to be a crucial factor in determining views on health. Basic conceptions of 'the health' are formed according to views on body. Views on body have been changed from the one that it is merely physical material, to the one that it is related to internal functions, and to the one that body and health are considered as the quality of life. These changes in views on body are connected with views on health: health is simply related to diseases and physical injuries; it is linked with the internal functions of the body; body and mind are one unit closely connected with each other; and body itself is the very quality of life.

논에 殺蟲劑 처리가 天敵昆蟲과 거미群集에 미치는 영향

李海浜,金胄弼,全正蘭 동국대학교 산업기술대학원 1993 산업기술논문집 Vol.1 No.-

An arthropod community structure in a rice peddy field ecocystem was investigated. Sampling was conducted using D-vac sucker at the Experimental Station of Dongguk University in Namyangju-Gun, Kyonggi province during the periods from August to October in 1992. During the period of investigation, 112 species, 34 families and 6 orders were represented for the insect cummunity in untreated plots, while 104 species, 41 families and 5 orders in treated plots. And among them, 45 and 31 species of entomophagous insect were listed from the untreated and treated plots with 17.5% vs 5.2% in the occupancy rate, respectively, suggesting that pesticide usage lead the reduced number of immigrating and emigrating natural enemies. The other hand, 25 species in 13 families of the spider were represented in the untreated plots whereas 15 species in 8 families in treated plots. Spiders which collected in untreated plots were twice as high in abundance as those in treated plots. Tetragnatha sp. (Tetragnathidae) was the most abundance species in treated plots. Dominant species of untreated plots, Piratasubpiraticus (Lycosidae), occurred in very low number in treated plots. During the growing season, the temporal pattern of species diversity are measured using species diversity (H'), species richness (S) and species evenness index (J'). The tendency of communities to return to its predisturbed state were observed in treated plots. The positive correlation was obtained for spider species diversity and prey abundance in untreated plots but in treated plots.

여자 체조 이단평행봉 연기에 대한 분석

이보선,박순호,이필영,최정현 龍仁大學校 體育科學硏究所 2001 體育科學硏究論叢 Vol.11 No.1

The purpose of the study is to help Korean women gymnasts get better grades in the international sports arena by understanding the world trends in this field based on the analyses of performances in the parallel bars, the weakest event among the four Korean women's gymnastic events. Value, connection value by which bonus points can be obtained, and start value were analyzed, excluding demerit marks in general performances, impressions, and art. The results of the study are as follows. In the analysis of value, the top four athletes implemented more parts than the average level while the four Korean athletes achieved less than the average level. According to the analysis of value parts D and E, the top four athletes received an average of 0.675 bonus points while the Koreans got 0.15, showing a great difference among them. The analysis of connection value by which bonus points can be obtained also showed stark contrast between the top four athletes and the Koreans marking bonus points of 0.50 and 0.075, respectively. The average start value of the top four athletes was 9.95, 0.925 higher than that of the Korean athletes of 9.025, which can be considered as a big difference. It is suggested that Korean athletes should focus on conducting high level of value parts and connection value to make greater achievements in the international sports arena, considering general demerit points were not included in this study. They are also needed to be confident in order to act to the best of their abilities.

자궁원발성 비호지킨 악성림프종 -3예 보고-

박찬필,고영혜,이중달,박문일,김경태,조삼현 대한병리학회 1995 Journal of Pathology and Translational Medicine Vol.29 No.3

신장장해 가토에서 Theophylline의 약물동태

차중권,이진환,최준식,김가나,범진필 조선대학교 약학연구소 1992 藥學硏究誌 Vol.14 No.1

This study was attempted to investigate the pharmacokinetics of theophylline in rabbits with folate induced renal failure. Plasma concentration and AUC of theopylline were increased in rabbits with folate induced renal failure compared with those of normal rabbits. Renal clearance and total body clearance were decreased in rabbits with folate induced renal failure compared with those of normal rabbits. Correlation of serum creatinine concentration and AUC, and correlation of serum creatinine clearance and renal clearance have linear relationship respectively. From the results of this experiment, it is desirable that dosage regimen of theophylline should be adjusted for effective and safe therapy in patient with renal failure in clinical pharmacy practice.

TNF-α 유전자형과 방광암과의 관계

정필두,김은정,엄민식,서정원,윤석중,김종석,이상철,김원재 충북대학교 의학연구소 2001 忠北醫大學術誌 Vol.11 No.2

연구목적: TNF-α는 일부 종양의 종양화 과정과 관련이 있는 것으로 알려져 있다. 본 연구는 TNF-α 발현에 영향을 미치는 TNF-α 촉진자 -308 부위의 유전적 다형성이 방광암과 관련이 있는지 유무를 알고자 시행하였다. 대상 및 방법: 유전자 분석을 위하여 환자 113명 및 대조군 109명으로부터 혈액을 채취하여 genomic DNA를 분리한 후 PCR-RFLP 및 direct DNA sequencing을 통하여 TNF-α유전자의 다형성을 조사하여 방광암의 발생, 병기 및 분화도와 비교 검토하였다. 결과: TNF-α 촉진자 -308 부위의 유전형은 대조군에서는 GG형이 83.5%(90례 및 GA형이 16.5%(19례)로 관찰되었으며 AA형은 없었다. 환자군에서는 GG 형이 85.4%(97례), GA형 및 AA형은 각각 13.1%(15례)및 0.8%(1례)에서 관찰되었다. 두 군 모두에서 GG형이 가장 많이 나타났으며 다음으로 GA형을 보이고 AA형은 1례의 방광암 환자에서만 관찰되었다. -308부위의 경우도 두 군 사이에 유전자형의 차이는 없었다(p=0.259) 분화도별 분포를 보면 grade I이 20례, grade II가 49례, grade Ⅲ은 34례였고 병기별로 표재성인 경우가 90례였으며 침윤성은 14례였다. 분화도가 나빠질수록 GA형이 증가하였다(p=0.04). 그러나 병기와 TNF-α promoter -308부위의 유전자형 사이에는 유의한 상관 관계가 없었다(p=0.123). 결론: 방광암 환자의 혈액에서 GA genotype이 관찰되는 경우, 분화도가 나쁠 가능성이 매우 높기 때문에 좀 더 적극적인 치료와 세밀한 추적관찰을 함으로써 방광암으로 인한 사망과 암의 진행을 예방할 수 있을 것으로 기대한다. Purpose : Tumor necrosis factor-alpha (TNF-α) is involved in tumorigenesis of several cancers as an endogenous tumor promoter. The purpose of this study was to investigate whether genetic polymorphism of TNF-α promoter region (-308) was associated with human bladder tumor. Materials and Methods: The DNA from 113 and 109 respective blood samples of bladder tumor Patients and control group was analyzed by PCR-based restriction fragment length polymorphism (RFLP) and direct DNA sequencing methods to characterize the genetic polymorphism of -308 promoter region of the TNF-α gene in bladder tumor patients. We compared the association of bladder tumor with genetic Polymorphism of TNF-α promoter region(-308) in relation to the stage, grade, recurrence and progressio. Results : Eighty-six percents(97/113) of bladder tumor patients and 83.5% (90/109) of control group showed genotype GG at -308 region of TNF-α. Difference in genetic variations of TNF-α promoter (-308) did not exist between bladder tumor patients and control group(p=0.259). Tumor grade was significantly related to the GA genotype (p=0.04). The higher is the grade in bladder tumor, the more frequent was the GA genotype. Tumor stage, recurrence and progression were not significantly associated with genetic polymorphism of TNF-α promoter region (-308). Conclusion: The GA genotype of TNF-a promoter region (-308) had a significant impact on TNF-α production and was related to higher grade tumor compared to GG genotype. TNF-α serum levels in bladder tumor patients were significantly higher than controls. These data suggested that TNF-α might involve the tumorigenesis of the bladder rather than treatment or prevention of bladder tumor.