AHP를 이용한 CT 및 MRI의 비용편익분석

조근태,김성조,김성민,김용우,김성재,조용곤 한국경영과학회 2004 經營 科學 Vol.21 No.2

The imports of used medical equipment such as CT, MRI have been rapidly increased every year. How to manage those medical equipment has been one of critical issues in the government sector. In this study, we demonstrate how benefit/cost analysis using the Analytic Hierarchy Process (AHP) can be applied to the comparison of used CT/MRI and new CT/MRI. The final results show that the new CT/MRI is more attractive than the used CT/MRI.

Three-Dimensional Porous Collagen/Chitosan Complex Sponge for Tissue Engineering

Kim, Sung Eun,Cho, Yong Woo,Kang, Eun Jung,Kwon, Ick Chan,Lee, Eunhee Bae,Kim, Jung Hyun,Chung, Hesson,Jeong, Seo Young The Korean Fiber Society 2001 Fibers and polymers Vol.2 No.2

A three-dimensional, porous collagen/chitosan complex sponge was prepared to closely simulate basic extracellular matrix (ECM) constitutes, collagen and glycosaminoglycan. The complex sponge was prepared by a lyophilization method and had the regular network with highly porous structure, suitable for cell adhesion and growth. The pores were well interconnected, and their distribution was fairly homogeneous. The complex sponge was crosslinked using 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC) and N-hydroxysuccinimide (NHS) to increase its boilogical stability and enhance its mechanical properties. The crosslinking medium has a great effect on the inner structure of the sponge. The homogeneous, porous structure of the sponge was remarkably collapsed in an aqueous crosslinking medium. However, the morphology of the sponge remained almost intact in a water/ethanol mixture crosslinking milieu. Mechanical properties of the collagen/chitosan sponge were significantly enhanced by EDC-mediated crosslinking. The potential of the sponge as a scaffold for tissue engineering was investigated using a Chinese hamster ovary cell (CHO-K1) line.

비·부비동 종양의 신생혈관 형성에서 COX-2 및 VEGF의 역할

도남용,박성용,조성일,윤혁수,박선홍,박영균,권대승,임성철 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

Background and Objectives : COX-2, the inducible form of cyclooxygenase(COX), is upregulated in transformed cells and in malignant cells, which have important roles in promotion of colorectal carcinogenesis, invasiveness and angiogenesis. Vascular endothelial growth factor(VEGF) may act as endothelial cell mitogen in various cancer tissues. It will increase tumor growth and angiogenesis. Aims of this study were to asses COX-2/VEGF expression and it's clinical correlation in sinonasal tumors and to investigate the effects on angiogenesis also. Materials and Method : The study samples were obtained from surgical removal of 27 cases of inverted papilloma(IPs), 5 cases of IP with malignant transformation(IP-MT), 16 cases of Squamous cell carcinoma(SCC) in sinonasal cavity COX-2 and VEGF expressions were assessed by immunohistochemical staining. Synchronism of COX-2/VEGF expression in one tumor cell was demonstrated with double immunofluorescence technique. Results : The expression rates of COX-2 were 37% in IP, 80% in IP-MT and 100% in SCC. The positive rates of VEGF were 29 6% in IP, 100% in IP-MT and SCC. COX-2 and VEGF expressions were increased as tumor progressed, and there is a positive correlation between COX-2 &EGF expressions. All clinical features which were compared are not associated with COX-2 &EGF expressions except malignant change in IP(p=0 028). Synchronism of COX-2/VEGF expressions was noted in all positive immunostaining samples. Conclusion : These findings suggest the role of COX-2 pathway could be involved in sinonasal tumor angiogenesis, which is modulated by VEGF COX-2 may act as autocrine factor in VEGF expression. There is a potential role for selective COX-2 inhibitors in the treatment of these lesions.

아파트경매에서 낙찰가율의 결정요인에 대한 연구

조상용(Cho, Sang-Yong),박승록(Park, Seung-Rok) 한국주거환경학회 2015 주거환경(한국주거환경학회논문집) Vol.13 No.4

In this paper, we study the highest bid price determination mechanism of the court auction markets for apartments that are under distraint because of the insolvency of the owner of the apartments. In addition to the typical variables used in previous literatures on the determination of highest bid price, we add the variables that represent the characteristics of the tenants categorized by the priority order of the tenants’ deposits in the distribution process of the money obtained from the auction of the apartments. Unlike our general perception, the results show that the presence of pretense tenants on the priority list of the distribution of dividend from the auction hardly affects the determination of the highest bid price. In addition, the presence of legal counter power of tenants against the landlord does not affect the highest bid price, either. The first policy implication of this paper is that to set up a fair institutional mechanism in court auction market for apartments under distraint, the auction court needs to ask the applicant of the auction to prove whether the listed tenants are true to eliminate the pretense tenants. The second policy implication is that the court needs to disapprove the seniority of the pretense tenants’ claim on the distribution of dividends from auction of the apartments.

위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구

노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

急性 骨髓性 白血病 患者 1例에 對한 臨床報告

조정효,유화승,최우진,이용연,서상훈,이연월,손창규,조종관 대전대학교 한방병원 2000 惠和醫學 Vol.9 No.2

AML is the most common type of leukemia in adults. AML(acute myeloid leukaemia) is characterised by a rapid accumulation of abnormal white blood cells in the blood and bone marrow, resulting in severe anemia, and possibly infection, and hemorrhage during the course of the disease. In general the prognosis of patient with relapsed AML is poor. At this time, however, the only potentially curative therapy for relapsed patients is allogeneic BMT(bone marrow transplantation). This clinical study were carried out 1 case of female patient aged 44 with relapsed AML treated by herb medicine. At the time of admission, she complained of mild fever, nausea, vomitting, abdominal pain, anorexia and no sign of bleeding. For the 10 days of admission, she was treated with Oriental-Western medicine and all the symptoms were disappeared. After that, the syptoms were aggravated because of secondary infection. Anyway, above result showed the possibility of Oriental therapy as Supportive Care in AML.

위상배열 초음파를 이용한 터빈 블레이드 루트부내 결함평가 기법 연구

조용상,정계조,박상기,김재훈 한국비파괴검사학회 2004 한국비파괴검사학회지 Vol.24 No.2

초음파검사는 재료의 표면 또는 내부에 존재하는 불 연속부를 검출하기 위해, 초음파를 재료에 전달시켜 검사하는 비파괴검사법의 일종이다. 이러한 일반 초음파검사 방법 및 일반 결함평가 방법은 복잡한 현상에서 반사되는 신호로부터 결함을 구분하기가 어려워 결함의 평가 및 검사결과에 신뢰성이 떨어지고 있는 실정이다. 따라서 이러한 crack성 결함의 발생 가능성이 높으나 기존의 초음파검사 방법으로는 결함 판별에 어려움이 있는 설비에서의 검사방법 및 결함평가 방법의 제고가 필수 불가결한 실정이다. 본 연구에서는 위상배열 초음파를 사용하여 크랙 검출능력이 높고 길이 평가가 가장 정확한 방사각도를 규명하고, 주요발전설비중 하나인 터빈에 적용하였다. 기존의 초음파 검사 방식이 아닌 위상배열 초음파를 이용하여 결함의 크기를 평가할 수 있는 신 기법 및 이를 이용하여 터빈 블레이드 루트부 내에 존재하는 미세 결함에 대하여 크기평가 방법 및 결함탐지 방법에 대하여 고찰하였다. Ultrasonic testing is a kind of nondestructive test to detect a crack or discontinuity in materials or on material surfaces by sending ultrasound to it. This conventional ultrasonic technique has some limitations in reliably detecting crack or accurately assessing materials in the case of complex-shaped power plant components such as a turbine blade root. An alternative method for such a difficult inspection is highly needed. In this study, application of a phased array ultrasonic testing (UT) system to a turbine blade, one of the critical power plant components, has been considered, and the particular incident angle has been determined so that the greatest crack detectability and the most accurate crack length evaluation may be achieved. The response of ultrasonic phased array was also analyzed to establish a special method to determine the crack length without moving the transducer. The result showed that the developed method for crack length assessment is a more accurate and effective method, compared with the conventional method.

폐결핵의 조기진단에 있어서 이중중합효소연쇄반응법의 유용성

조성란,최영진,김용훈,이철세,김영창,김휘준 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

Background: Pulmonary tuberculosis is a great public health problem in Korea. Early detection of Mycobacterium tuberculosis (M. tuberculosis) in clinical samples becomes more and more important in the control of tuberculosis. Recently, molecular methods have been applied to early detection of M. tuberculosis. Methods: To elucidate the effectiveness of nested polymerase chain reaction (PCR) in early diagnosis of pulmonary tuberculosis, we peformed Acid-fast bacilli (AFB) stain, AFB culture, and nested PCR on 84 sputa. Results: 8 (9.5%) specimens were positive by AFB stain, 17 (20.2%) by AFB culture, and 15 (17.9%) by nested PCR. Using AFB culture as standard method, the sensitivity of AFB stain and nested PCR was 47.1% and 82.4%, respectively. The specificity of AFB stain and nested PCR was 100% and 98.5%, respectively. Conclusions: Nested PCR was more sensitive than AFB stain and had shorter processing time(24-48hrs) than AFB culture. So it may be effective to use nested PCR in order to detect M. tuberculosis when AFB smear Is negative.