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은행잎추출물이 배양된 사람 섬유주세포의 생존에 미치는 영향
김성재,강현구,김재우 대한안과학회 2006 대한안과학회지 Vol.47 No.4
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Purpose: To investigate the effect of Ginkgo biloba extract (GBE, EGb-761) on the survival of cultured human trabecular meshwork cells (HTMC). Methods: Free radical scavenging activity of GBE was assessed with a DPPH assay. Primarily cultured HTMC were exposed to 10 and 100 ?g/ml of GBE. 0.3 mM sodium cyanide and 100 ?M hydrogen peroxide were added to the culture medium with GBE for 48 hr. Cellular survival and nitrite production were assessed by MTT assay and Griess assay, respectively. Results: GBE showed free radical scavenging activity. GBE increased the cellular survival of HTMC significantly in a dose-dependent manner under hypoxia or serum-deprived condition, but not to hydrogen peroxide. GBE increased nitric oxide production but not to statistically significant levels. Conclusions: GBE promotes proliferation and has cytoprotective effects in the context of HTMC exposed to serum-deprived or hypoxic conditions. However oxidative stress induced by hydrogen peroxide did not have an effect on proliferation of HTMC. In addition these effects were not related to the production of nitric oxide.
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[연구논문] 2차적 저작물의 법리 : 편집저작물을 중심으로
김성재 한국출판연구소 1996 출판 연구 Vol.8 No.-
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출판행정의 문제점과 출판진흥정책방안 : [특집 I] 출판문화정책의 방향
김성재 한국출판연구소 1991 출판 연구 Vol.3 No.-
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$Mn_{0.05}Mg_{11.9-2x}Fe_{4x}O_{4+r}$+2wt%$Al_{2}O_{3}$ 조성내 Fe량 변화에 따른 마이크로파 손실 특성 연구
김성재,정명덕 대한전자공학회 1994 전자공학회논문지-A Vol.31 No.6
In order to study the effect of D.C resistivity of sample on electromagnetic loss of ferrite at microwave frequency, samples were prepared for having differences in resistivity of an order of two. Microwave permeability($\mu$), permitivity($\varepsilon$) and effective linewidth(${\Delta}H_{eff}$), and ferromagnetic resonance linewidth(${\Delta}$H) were characterized. Tan${\delta}{\mu}$, tan${\delta}{\varepsilon}$ and ${\Delta}H_{eff}$ were decreased with increasing the resistivity and (${\Delta}$H) was increased with increasing Fe concentration, which was due to an increase of anisotropy magnetic field (=Ha).
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김성재,차진경 알코올과 건강행동학회 2016 알코올과 건강행동연구 Vol.17 No.1
Objective: One of the important factors that leads to relapse amongst alcoholics is a negative emotional state, and the factors affecting negative emotions include sexual desire or sex life. Although relapse into alcoholism is closely related to sexual experience, few studies have been done on sexuality and sexual experiences among alcoholics in Korea. The purpose of this study was to explore the sexual experiences of recovering male alcoholics and enhance our understanding of this issue in order to develop relapse-prevention strategies. Methods: The participants included 19 male recovering alcoholics who were diagnosed as alcoholics and maintained sobriety for more than 6 months after treatment. This work includes a secondary analysis of focus group interviews conducted on 17 participants published in “A Study on Sex Education Requirements of Recovering Alcoholics.” This study added two in‐depth interviews of key informants to the qualitative data. Thematic content analysis methods were used. Results: Our results revealed that sexuality and the sexual experiences of recovering alcoholics could be divided into 4 categories: “distorted sexuality,” “wounded sexuality,” “addiction-aggravating sexuality,” and “recovering sexuality.” We found that distorted ideas of sexuality and psychological wounds related to sexual experiences affected alcohol dependency in the patients. Sexual dysfunction that males experience during the recovery process interacts with the desire for intimacy, triggers the impulse to drink, and aggravates addiction. On the other hand, participants in longer-term recovery experienced a perceptual change regarding sexuality. They came to perceive sexual behaviors and sexual life as emotional sharing and an expression of friendliness, whereas sexuality had previously been viewed as a symbolic expression of power and a method of pursuing pleasure. Conclusion: In this study, we examined sexuality and intimacy issues that recovering male alcoholics face, and explored the positive and negative effects of various sex-related behaviors on recovery. Our results can be used as basic material for the education of professionals in the addiction field and in developing intervention programs to encourage recovering male alcoholics to develop healthy sex lives.
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김성재 한신대학교 신학사상연구소 1994 신학사상 Vol.86 No.-
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