논문 : 한옥 생산성 향상을 위한 설계지원 방안에 관한 연구 실무 -부재가공 프로세스 분석을 중심으로-

이현우 ( Hyun Woo Lee ),정성원 ( Sung Won Jung ),전한종 ( Han Jong Jun ) 디자인융복합학회 2012 디자인융복합연구 Vol.11 No.5

기존 한옥의 계승을 위한 관련 연구가 진행되고 있으나, 한옥 보급에는 실용성을 띄지 못하고 있다. 이는 한옥 시공기술의 복잡성과 자재 생산기술 부족으로 인한 제한적 범위 내에서 공사가 진행됨에 따라 높은 공사비를 원인으로 꼽을 수 있다. 이에 따라 현재 전통 한옥이 가진 정체성을 살리고 현시대에 보급될 수 있는 신 한옥으로의 진화를 위해 부재간의 연관을 분석하고 조립하는 방식을 지식으로 구성하고 디지털 모델링을 함으로써 공사비 절감이 가능케 하는 방법 등이 연구되고 있다. 본 연구에서는 한옥 설계자를 고려한 효율적인 부재 가공 정보 지원을 목표로 한옥 부재 실무 가공 분석을 통해 경제성, 시공성을 파악하고 최적화 방안을 위한 한옥 부재 제작 CNC 시뮬레이션을 통해 효율적인 가공 프로세스의 발전 가능성을 예측하여 최적화된 부재가공 정보를 제안하고 이를 기반으로 한옥 수요자들을 위한 설계지원 방법에 대한 구체적인 방안을 제시함으로써 한옥의 생상성 향상에 기여하고자 한다. There have been a lot of studies about the Han-ok, the Korean-style house, in perspective of the inheritage of existing ones, but there are no practicality in the supply of Han-ok. The cause is considered to exist in the complexity of Han-ok and the techniques required to manufacture its components and in the relatively higher construction expenses in the process which is within restricted range. On the contrary, in order to preserve the identity of traditional Han-ok and encourage the evolution to create a new Han-ok that can be supplied to the present period, there has been studies that analyzes the connection between sub-components and assemble them into a digital model which can possibly decrease the expenses spent on construction. The research`s objective is to provide valuable information for Han-ok designers, which contains methods on manufacturing sub-components effectively. Furthermore, by analyzing the current manufacturing method`s workability and economic feasibility, the research can obtain an optimum alternative for improving Han-ok`s production. Also by using CNC simulation, the possibility of an effective production can be predicted, as well as the information that can lead to the optimum method for an efficient sub-component manufacturing and suggest a specific resolution which can also affect on the improvement of Han-ok productivity.

원행을묘정리의궤 중 조리면에서 본 죽상 . 미음상 및 현륭원에서의 상차림고

김상보,이성우,한복진 한국식생활문화학회 1989 韓國食生活文化學會誌 Vol.4 No.4

To analyze dialy meal of royal meal, studied Jook Soora Sang (Rice Gruel), Mieum Sang (Thin Gruel) and Bankwa Sang, Soora Sang in Hyun Neung Won were on record Wonheng Ulmyo Jungri Euigwae (1795). Historic book "Jungri Euigwae" described the king's visit to his father's royal tomb "Hyun Neung Won", during the domain of Cheung Jo, the 22nd king of Choson Dynasty. The results obtained from this study are as follows. Rice Gruel (Jook Soora Sang), taken before breakfast, was arranged the same as the Soora Sang. The table for thin gruel (Mieum) was arranged in three kinds of sets; one for thin gruel, the others for stewed meat (Goem) and sugared fruit (Jeong Kwa). The diet seems to have been quit scientific and restorative. Bankwa Sang and Soora Sang in Hyun Neung Won was arranged the same as the other Bankwa Sang and Soora Sang. Therefore setting the table of royal meal had a rule.

靑少年의 社會 및 國家意識에 關한 調査와 그 强化策

李宇榮,金相漢,韓點洙,洪亮杓 慶北大學校 平和問題硏究所 1977 평화연구 Vol.2 No.-

1. Problems Our people and nation are in serious ordeal and also aur concentration of attention and effort to overcome the ordeal are, we can say, very praisable. The violent changes in the aspects of politics, culture, society and economy are at last exposed of the danger of loss of our values. In such changing social phenomena, we with no exception are all experiencing the morbidness caused by them. It is exactly the Yu-Shin (Revitalizing Reform in 1971) and Saemaul(New Community Movement) that supplied and showed the direction of nation-state as r revolution in climate of unestablishment of new values with loss of old ones. It can be true tht we have reaped great fruits in political, economic, social and cultural fields in such hard environments. Then it is very useful project not only in academic and policy-reponse fields, but also in education areas that we try to survey and analyze the Juvenile's response to the national mevements and the changes of concious-structures. 2. Purposes The purposes of the study are: ① to grasp the reality of the Juveniles' view of value by sex, region, age etc., ② to review their responses to government's achievements, policy and its direction, ③ and to diagnose their approach to desirable view of values and degree of achievement. We belive in that concious-reality whcih we can find in process the study will be very important materials to education-policy. 3. Study-methods ① We did survey and analysis of juvenile's veiw of values. ② We set the juveniles of whole nation as the mother group, however, excluding bipolar ones such as Seoulities and the juveniles living in islands and remote hamlet, finally selected the objects of three regions such as Kyeong sang, Chung Cheong and Cheol Ra regions and compared them by various dimensions. Except for detail-survey of Kyung Buk province, we set the objects of students of 3rd grade of sr. high school, professional school (Jr. College) and college in other regions, and surveyed subregionally by large city, medium size city and ruralfishing villages, and by sex. ③ Total number of the surveyed is 3,229 and by regionally, they are 1,725 in Kyung Sang, 616 in chung cheong and 888 in Cheol Ra. ④ The questionairs are handed directly by surveyers and colloected on the spot as soon as they are filled out. ⑤ The view of value by social strata and response degree to policy are tested by %² including the differences among regions, sexes, ages and ect., and to the question required quantitative evaluation, we gave +10, +5, 0, -5, -10 pionts as consent-dissent continuum and calculated the mean number and to other questions, the responses were shown by %. 4. the Juvenile's social and collective life ① Social and collective life of the Juvenile is relatively good in social-conciousness. The view or moral-order was shown 5.31 of f(R)/N. Generally juveniles are answered "waiting for one's turn" in the line at the station of public transit. Girls are shown to be a little better-observer in public order than boys, and teenagers better than the twenties. The view on law-abiding is shown 3.97 of f(R)/N and generally in case of minor offence, they expressed around "be shame". Criminal conciousness is getting stronger from large city to rural and fishing village. There are great differences between the two. Girls are stronger in the conciousness than boys and teenagers stronger than twenties. It is particularly a problem that twenties' f(R)/N is less than 1.72 and theyt are inclining to "may commit so". To the degree of success in the Reform of General Administrative Affairs by our government, f(R)/N is shown 4.94, responding generally "there are a bit fruitful". To the question, degree of recognition is getting stronger to rural-fishing village. Male is stronger than female and teenagers stronger than twenties. And in the hot-bed of corruption, enterprises and tax office are shown 29.63%, and politician 23.27%. General administrative office, judicial and police offices are high in distrust in rural-fishing villages, and tax office, enterprises and politician are getting higher in distrust to larger cities, however, educational institutions are high of trust in medium-size city. Judicial office, enterprises, tax-office, education instution and politician are in high ofdistrust by female, and general administrative office is in high of distrust by male. Teenagers are in side distrust in judicial, police, enterprise and education institutions, and twenties are in side of distrust in general administration and politician. And degree of trust in shamanism is low of 4,76, generally selecting"almost deny", rural-fishing village, female and twenties are higher trust on superstition than large city, male and teenager respectively. The view on national value is shown 2.42. In the village, female, and twenties, cohesion is shown stronger than in city, male and twenties respectively. ② In measurement of juvenile's conciousness on inter-relationship, they are strong in degree of participation of family and community affairs, but in conciousness on collective life, unsatisfactory. They degree of satisfaction in family life is 4.68, generally "in side of satisfaction". It is getting more satisfaction from the villages to large cities. Juveniles in the villages seem to be much unsatisfied with their family, and females than males and twenties than teenagers are higher in satisfaction. Participation degree in community affairs is shown 8.00, generally close to "active participation". Villager than city-dweller and teenagers than twenties are higher in conciousness of participation. The degree of non-alienation from collective life is 2.71 showing the response of "relativelly no particular alienation" and "so on so" generally. Villager than citizen, male than female and twenties than teenagers are higher in alienation. The degree of acception of individual idea in collective life is shown 1.81, close to "so on so". Male's unsatisfaction is higher a little. Their preferable occupations are in priority of production enterprises(28.73%), public service(26.32%) and agriculture-forestry(19.23%). The popular occupations are agriculture-forestry and public service in rural-fishing villages, production-enterprises in medium -size cities and commerce-industry in large cities. Males are favorable to take agriculture-forestry, production and free enterprise and females are to bublic servidce. For teenager, agriculture-forestry and public service are high in priority and for twenties other areas of occupation are high. ③ In conciousness on traditional culture and identity, they are supporting the thought of "loyalty and filial piety", showing 5.36 and generally selected "It is great view on social order though required a lot of revision". females and teenagers are more active on the though required a lot of revision". Females and teenagers are more active on the thought than males and twenties respectively. The capability of foreign affairs in aspects of independent diplomacy was measured to 2.25 barely approaching to "be seen independent efforts". Trust was seen in females, teenagers and the villagers. In cultural conciousness, national superiority was shown very apparently as 28.67%. ④ In aspects of democratic and national conciousness, they showed the degree of satisfaction at democratic society. It was measured through the fruits of Yu-Shin Reform and resulted in 2.17, responding better in females, teenagers and the rural than in males, tweenties and the urban. On 6 years of current term of congressmen, 45.46% responded on "too long", 38.24% on "ordinary" while in rural-fishing villages, they showed high support of 48.90% selecting"appropriate". Many urbans are on "too long" (49.51% in large cities and 49.62% in medium). 44.04% out of females showed the response of "appropriate" while 47.22% of males did that of "too long". 44.43% of teenagers responded "appropriate" while 53.13% of twenties did "too long". National conciousness measured through "degree of confident explanation on national flag" was shown 2.87, responding "can explain to a certain extent" and "can explain" as medium quantity. The villagers, males and teenagers are shown high confidence of it. To the present big increase in national power, juveniles resopnded high motive of "people's self-conciousness" and "great leader" while female showed relatively hgh response on "New Community Movenment" and "Result of education" and so on. teenagers showed "great leader" and twenties did "Result of Education". The view of ideal nation measured through "approach to welfare state" showed 3.87, close to "be seen the effort for welfrare state". The villager, female and teenager showed high response to the positive side. as the way of education how to plant Korean Democracyh among the people they replied "Explaining Korean particular environments" is most useful as 41.40%. Juveniles in medium-size cities, males and twenties showed mainly the above answer. The patriotic attitudes measured through participation of nationa defense showed 8.47, responding close to "participate battle immediately". It can be said very active response that significant number of females selected the attitudes of "support in rear theater". The villagers, males and teenagers are strong in loyalty. If we consider females' particularity, we cannot say they are weaker in loyalty. However it is very considerable that there are responses of "may decide on the scene then", "immigrate abroad" and "negociate with enemy and live together though a few. We are sure that our goverment be required educate and enlighten them immediately. 5. Juvenile's view of Security and National Unification ① Through the measurement of conciousness on communism the surveyer saw that critical ability and attitudes of it is the nearest short cut to anti-communism a key to victory over it. In this dimension, the surveyer analyzed sources of knowledge from masscom 971.47%) and exposed the weak points on lectures and those on government's activities of public information, while rising of masscom's importance. The comparison of South-North living standards showed that 51.34% responded "South Korea is much superior" and 35.08% "superior". Then total 87% of juveniles are on our superio9rity and the rest (13%) showed "equal" or "don't know". In large cities "superiority" was low in % of males and twenties. The confidence in pursuading North Korean on our democratic society's strong points was shown 73.55% of "be confident". However it is very insufficient in education on communism that out 87% of "Our superiority", some 13% are not confident in pursuasion. 13.47% are shown "will decide on the spot to meet" and 5.85% "need not pursuade". The villager, male and teenager have strong response to the above 7.6% of "national symbols". Legality of national foundation" for the urbans and males and twenties "legitimacy of the country" for villagers, and "national culture" for females and teenagers are shown as the grounds of the legitimacy. ② The conciousness of national security measured through the question on aug. 18 Incident(1976) at Pan Mun Jeom appeared following; the causes of the Incident are shown in order of "domestic unstability of North Korea" 928.92%) "shifting responding dissent, 48.77% are on " a little humiliating" and 21.12% are on "utter humiliating". Only 23% showed satisfaction at the counteraction. They showed youthful active counteraction of purnishment, however, it also may cause some anti-American or uncredibility over United States. By region, sex and age, the re3sponses were diffeent greatly. Juvenile's predictions on the possibility of Sino-Soviet Support in case of total war are following; some 80% calculate psychologically that both China and Russia will surely support North Korea militarily and materially, 45.09%, "material support by both". To the way of spritutal militarization, they responded in order of "introduction of North Kjorean affairs" (29.48%), "explanation of N. K's attitudes"(26.20%), "education on N.K's strategy to the South"(20.50%), "to criticize communist thory"(17.96%) and so on. Different responses among regions, sexs and ages are apparent. The Juvenile's pride to foreigner is shown 0.92% of f(R)/N, a little higher to "equality". Villagers are relatively high, medium-size urbans are lowest, and females and teenagers are high in pride to foreigners. ③ To the question on Unification time as one of the conciousnesses of Unification, they responded in order of "impossible forever" (40.16%), "in 30 years"(23.59%) and "in 10 years" (17.99%). It is very undesirable that possibility of Unification is renounced gradually among juveniles. Juveniles are in deadly need of education and enlightenment on increase of Unification conciousness. Differences among the given variable are very apparent. In large city, females and twenties, the re3nunciation is shown greatly. The reasons of Unification are shown in order of "single-nation" (36.38%), "political stability"(32.48%), "preferable to international competition"(20.53%) and so on. Urbans of large cities, males, twenties responded "preferable to Int'l competition", female did "political stability" and teenagers did "single-nation". To "the factors of obstacles to Unification" are shown "antagonistic ideologies" (64.16%), interest situations among Big Four" (18.14%), "North Korean reluctance"(9.60%)and so on. "Interest Situation among Big Four" is shown in large cities and twenties, "N.K's reuctance" in males and teenagers. and "antagonistic ideologies" in females. The ways of Unification are appeared in "economic development"(46.67%). "South-North Dialogue" (26.72%) and so on. "S.N Dialogue" in the villagers, females and teenagers, "Military March for Unification" in males, and "none available" in twenties are expressed relatively high. 6. Conclusion As mentioned above, social conciousness among juvenile is generally good, however, their alienation may be problematic a bit and capabbilty to foreign countries and national conciousness on democratic society are insufficient. However, defence conciousness is highly praisable. That the main sources on communism appeared to be masscom is required to reconsider. Juvenile's view of superiority in living to the North is very confident attitudes and their demandes of more information on North Korean reality and their attitdes toward S. N. Talk as a way of spiritual strengthening is needed to consider by goverment, and some policy-arrangements must be required. Renunication of Unification possibility as "impossible forever" is terrible and therfore, we need to educate and enlighten them for increase of the condiousness. "Military march for Unification"(11.30%) and "no way available"(3.37%) on Unification are surely problematic. In these re3spects, the education on Unification and anticommunism should be strengthended more. To the idea of "loyalty and filial piety", our juveniles are very positive, but indicated "requring a lot of revisions" Then the idea is required significant study and analysis in order to establish as a new value.

신장이식 환자에서 HCMV 항원혈증 검사의 임상적 유용성

김탁,성흥섭,박관태,김송철,김성한,최상호,김양수,우준희,박수길,한덕종,이상오 대한감염학회 2009 감염과 화학요법 Vol.41 No.2

Background : This study was performed to determine the cut-off value and the predictability of symptomatic human cytomegalovirus (HCMV) infection according to the peak value of HCMV antigenemia assay in kidney transplant recipients. Materials and Methods : We reviewed the results of HCMV antigenemia assay (Chemicon, CA, USA) in patients who received kidney transplantation at our institution from May 2003 through May 2008, and investigated the existence and the type of HCMV infection by the medical record review. Patients who underwent the test only once during the episode or those who received ganciclovir for more than 48hrs before the test were excluded. The receiver-operator characteristic curve was drawn and the point showing maximum likelihood ratio (LR) was chosen as the cut-off value of symptomatic HCMV infection. Results : A total of 689 episodes were screened and 134 episodes were enrolled. Thirty-three (24.6%) episodes were symptomatic HCMV infection, 23 (17.2%) episodes were associated with HCMV syndrome, and 10 (7.5%) episodes were tissue-invasive diseases. The maximum LR was 7.5 (95% confidence interval, 4.014.2) and the cut-off value was 29.5 cells/200,000 WBC. The sensitivity, specificity, Positive predictive value, and negative predictive value were 66.7%, 91.1%, 71.0%, and 89.3%, respectively. Conclusions : The cut-off value of symptomatic HCMV infection by the peak value of HCMV antigenemia assay in our study was similar with previous results, although the sensitivity was relatively low.

국내 한의학 학술지에 발표된 동의보감 연구 현황 조사

한창현(Chang-hyun Han),박상영(Sang-young Park),권오민(Oh-min Kwon),안상영(Sang-young Ahn),안상우(Sang-woo Ahn) 한국의사학회 2009 한국의사학회지 Vol.22 No.2

Background : To understand Korean medicine it is crucial to first understand medical aspect of ‘DongUiBoGam’. It is also meaningful that it became one of the influential book even to posterity. Also based on the apprehension, we can take a view of development of Korean medicine led by ‘DongUiBoGam’. Objectives : This study aims to review the status, study field, specialist of DongUiBoGam. In the process, this review will grasp trends in this field of studies and will direct further researches into the right direction. Method : The computerized Korean databases were searched from their respective inceptions up to December 2008. The search terms used were ‘DongUiBoGam’ and random or Korean language terms related to DongUiBoGam. Several specialized journals were also manually searched for relevant articles. Result : Since the 2000s, DongUiBoGam papers in the Korean Literature is increased. Published 58 papers on The Korean Journal of Oriental Medical Prescription were more than the other journals. 58 papers published in The Korean Journal of Oriental Medical Prescription are the best in many areas related to Korean medicine. Most people have submitted papers related to DongUiBoGam was Woo-yeal Jeong. Conclusions : ‘DongUiBoGam’ research is conducted and current tendency and outlook for ‘DongUiBoGam’ is carried out focusing on several associations.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

李圭晙의 生涯와 思想的 傾向

권오민(Kwon Oh-mi),박상영(Park Sang-young),안상영(Ahn Sang-young),한창현(Han Chang-huyn),안상우(Ahn Sang-woo) 한국의사학회 2009 한국의사학회지 Vol.22 No.1

This article conducted an pilot study on Lee Gyu-Jun(李圭晙)’s life and thoughts. He championed, and is mainly based on, old annotations of ancient Confucian bibles古文 that were made in the Han漢 and Tang唐 era in Chinese history and consequently took additionally into account Zuxi朱熹’s annotations on Confucian bibles. This cause big trouble to him in conservative Gyeong Shang Province(嶺南). He participated in the Confucian Religion Movement孔敎運動 and proposed constitutional monarchy as a new polity fit for changing Korean history. He closely interacted with many resistants to the Japanese rule of Korea and had a mixed perspective on Western culture, science and technology, and social system, positive or negative, contingent on cases. He made great footprints in the history of both modern Korean medicine and philosophy. Thus there is an urgent need for the overall study on Lee Gyu-Jun in every aspect.

열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

순천향대학교 학생들의 거주형태별 환경, 보건 및 복지실태

한성현,송라윤,한동우 순천향대학교 사회과학연구소 1998 순천향 사회과학연구 Vol.3 No.2

Three major factors influencing students' general well-being of school life were investigated: environmental, health, and welfare. A Survey was conveyed among all attending students of Soonchunhyang University by a structured questionnaire method to which was follwed by a complementary survey to explore and identify the housing situation of school area residents by the trained interviewers. Respondents tended to show relatively low degree of satisfaction regarding almost items regarding environmental and welfare conditions adressed. Residence types were significantly related to three factors. Research results suggest that more programs to meet the students' needs of environmental, health, and welfare services and facilities be provided.