종합검진센터 내원자에서 관상동맥질환 위험요인들의 분포

이충원,이종영,박종원,윤능기,김영조,이현우,이무식,서석권 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

1991년3월부터 8월사이에 대구시에 소재한 1개의 대학병원의 종합검진센타에 내원해서 종합검진을 받은 남자 422명(69.9%)과 여자 182명(30.1%)을 대상으로 하여 심헐관계질환의 위험요인들의 전체적인 분포를 보았다. 평균 연령은 남자가 43.3(표준편차, 10.3), 여자가 44.4(표준편차, 10.8)였다. 남자에서 연령에 따라 0.05 수준에서 통계적인 유의성을 보인 위험인자는 혈청 총콜레스테롤(TC). 트리글리세라이드(TC), 고밀도 지단백콜레스테롤(HDL), 저밀도 지단백콜레스테롤(LDL), 수축기혈압, 비체중, A형행동양상이었으며 생활습관으로서는 음주, 흡연, 규칙적인 운동, 우유와 커피섭취, 수면 등이었다. 여자에서는 TC, TG, LDL, 수축기와 확장기혈압, 비체중 그리고 커피섭취와 수면 등이었다. 남자에서 총콜레스테롤의 평균은 181.7mg/dl(표준편차, 32.2), 여자는 182.5mg/이(표준편차, 42.2)였다. 대부분의 위험인자들은 구미의 수준에 미치지 못했으나 남자에서 흡연율이 전체적으로 61.8%로 높으 수준이었으며 특히, 20~29세가 72.9%, 30~39세가 75.2%로서 다른 연령군에 비해 상대적으로 높았다. 여자에서는 전체적으로 6.0%에 지나지 않았다. 확장기혈압 90mmHg 이상을 고혈압자로 정의했을 때의 유병률이 여자 전체대상자에서 24.7%로 높았으며 50-59세는 표본수가 적어서 문제가 되었으나 53.1%였다. 어떤 인구집단내에서 총콜레스테롤의 평균이 200mg/dl 미만이면 고혈압과 흡연의 인구집단의 수준에 관계없이 관상동맥질환(coronary heart disease)의 발생은 드문 것으로 보고가 되고 있으므로 당분간 관상동맥질환 발생률의 급속한 절대적인 증가는 힘드리라 사료된다. 그러나 이러한 결과는 본 연구의 대상자들이 대표성을 지니지 못하며 건강검진센터에 자발적으로 내원한 사람들이므로 해석에 주의를 요한다. Authors examined the distributions of the risk factors for the coronary heart disease in the 422 male (69.9%) and 182 female (30.1%) visitors to the health examination center of a university hospital located in Taegu March to August 1991. Mean age of males was 43.3(standard deviation, SD 10.3) and that of females was 44.4(SD 10.8). Total cholesterol(TC), triglyceride (TG), high-density lipoprotein and low-density lipoprotein cholesterol(LDL), systolic blood pressure, Quetelet index, and Type A Behavior Pattern, and some of life habit variables(alcohol intake, smoking, regular exercise, milk and coffee intake and sleeping) were statistically significant in age groups of the males(P<0.05). In the females, TC, TG and LDL, systolic and diastolic pressure, Quetelet index, coffee intake and sleeping were statistically significant in age groups (P<0.05). Mean of total cholesterol was 181.7㎎/dl(SD,32.2) in males and that of females was 182.5㎎/dl(SD,42.2). Most of the risk factors levels were lower than the Euro-Americans', while smokers were high with 61.8%, especially 72.9% in 20-29 age group and 75.2% in 30-39 age group in males. In females, smokers were just 6.0%. Hypertensives defined by more than 90mmHg diastolic pressure were 24.7% in females, particularly 53.1% in 50-59 age group, but size of the strata was rather small(N=49). In the light of the report that coronary heart disease is uncommon irrespective of population levels of smoking and hypertension, where average total blood cholesterol level in a population is low(<200mg/dl), it is not likely that the absolute increase of the number of the coronary heart disease will increase markedly in the near future. But cautions should be exercised in interpreting the results of this study due to the lack of representativeness and volunteerism. .

영구형 항서맥 심박조율기 환자의 장기추적관찰

최현석,이무용,최영진,최성준,김효수,손대원,오병희,이명묵,박영배,최윤식,이영우,이명용 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.5

사후분해 시체에 대한 법의학적 접근

최영식,이상용,김유훈,조갑래,이봉우,양경무,정낙은,서중석,이한영,이원태,강현욱 大韓法醫學會 2000 대한법의학회지 Vol.24 No.2

Disposal of a homicide victim by dismemberment is rare, but individual cases are on record in most major medicolegal departments. Recognition of postmortem mutilation may be of importance in the interpretation of certain murders committed by sexual perverts and other mentally deranged individuals and sometimes performed for the sole reason of easier disposal of the body. Postmortem dismemberment is usually readily recognizable as such; The edges of the injuries are dry and lack evidence of bleeding. The joints may be disarticulated without fracture, or the use of an axe or saw may be evident from examination of bones. Parallel horizontal or oblique furrows in the bone surface are caused by skipping of the saw prior to establishing depth. Such patterns on the bone may assist in identifying the particular saw involved. So we report 25 dismembered corpses that autopsied in National Institute of Scientific Investigation. This paper can help in attempting to establish not only the first criminal investigation steps but also the medicolegal approach methods in unidentified and dismembered deaths.

흰쥐의 뇌, 척수 및 신경절에서 내장기관과 관련된 신경원의 추적에 관한 미세형태학적 연구 -Ⅰ. 부교감 운동신경 세포체의 표지부위

이창현,최종림,오인균,정동인,송창호,이무삼 대한해부학회 1996 Anatomy & Cell Biology Vol.29 No.4

인스텝 슛팅 동작에 대한 운동학적 분석

이용구,김무영,이한혁,조현영 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

The purpose of this study was to investigate the kinematic variables of the lower extremity during the Soccer In-step shooting motion. To conduct an investigation, five soccer players(skill group) and five students(less-skill group) in the high school were participate in this study. They were videotaped using three video cameras with the frame rate being 60㎐. This data was then reducted to 3D coordinates using the DLT(direction linear transformation)method. It was concluded that; Medio-lateral(X) displacement of the skill group was larger than that less-skill group and antero-posterior(Y) displacement of the skill group was smaller than that less-skill group. Velocity transfer of the skill group was more effectiveness than less skill group. The sequence of the maximal joint velocity of the kicking leg was the hip, knee, and ankl joint. It is considered very important that the sequence of the laximal joint velocity is from the proximal to the distal in order to increase the foot velocity at the impact. Trunk angle of the skill group was smaller than that less-skill group. And then ankle joint angle of the skill group was larger than that less-skill group.

신부전이 동반된 당뇨병 환자에서 발생된 침습성 모균증 : 수술과 Liposomal amphotericin B 및 GM-CSF 병합 요법에 의한 성공적인 치험 1예

이원영,오기원,임국희,장재혁,이동건,최정현,강무일,신완식,차봉연,이광우,손호영,강성구 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.4

저자들은 신부전이 동반된 당뇨병 환자에서 발생된 부비동형 모균증에 대하여 수술과 함께 liposomal amphotericin B 및 GM-CSF의 복합치료를 하여 성공적으로 치료한 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Mucormycosis (zygomycosis) primarily affects diabetic or immunocompromised patients and typically progresses rapidly, necessitating surgical excision and antifungal therapy with amphotericin B. Large doses of amphotericin B are needed for cure, but it has the risk of causing significant renal toxicity. The recent development of liposomal amphotericin B allows antifungal therapy to be administered with potentially improved efficacy and reduced nephrotoxicity. We have experienced a case of paranasal mucormycosis successfully treated with surgery, liposomal amphotericin B and GM-CSF. A 59-year-old male suffering from diabetes mellitus for 6 years was admitted with pain at left maxillary area. He was diagnosed as mucormycosis after cytologic exam on the necrotic nasal mucosa, which showed typical hyphae. He have had diabetic nephropathy with macroproteinuria and had rapidly rising serum creatinine levels with the amphotericin B treatment: creatinine levels reverted to basal level with the use of liposomal amphotericin B. Despite surgical excision and continued antifungal therapy, his infection was not effectively controlled. Therefore, GM-CSF was administered additionally to improve phagocytic activity of leukocytes. He was finally cured after receiving a combination of aggressive surgery, liposomal amphotericin B and GM-CSF. To our knowledge, this is the first detailed clinical description of the treatment of mucormycosis with liposomal amphotericin B in Korea.

계면활성제의 토양흡착에 대한 특성

신현무, 이상화 경성대학교 환경문제연구소 2000 環境硏報 Vol.10 No.1

Surfactant washing process being operated in ex-situ mode could be appropriate one of the most effective remediation alternatives for NAPLs(non-aqueous phase liquids) in soil. The adsorption of sufactants has been concern of the reduction of expenditure and the increase of efficiency. Through the result of estimating the extent of adsorption of surfactants to soils, notion sufactants showed higher adsorption to soils than anion surfactants. From the results of evaluating which model could explain the surfactant adsorption to soils, it was determined that anionic surfactants were described well with Langmuir adsorption isotherm model, while nonionic surfactants were with Freundlich model.

韓國에 대한 開國政策 小考

李玄武 건국대학교 1980 樂圓誌 Vol.15 No.1

한국은 개국시 부산왜관을 통해 일본과 제한된 교류를 갖기는 했으나, 이를 제외하고는 전근대적인 종속관계로 이루어진 대청의존관계가 대외관계의 전부였다 해도 과언이 아니며 구미국가와는 아무런 관계도 갖지 않았다. 따라서 한국은 구미사정에 극히 어두웠으며 청국을 통해서만 구미국가에 대한 정보를 입수할 수 있었다. 이러한 한국에 천주교가 먼저 전래된 것은 한국의 개국과정으로 보아 불행한 일이었다고 할 수 있을 것 같다. 유교적 가치관과 배치되는 천주교는 구미인들이 야만인이라는 왜곡된 관념을 확증해 주는 작용을 했기 때문이다. 한국정부가 천주교를 사교로 취급하고 1801년(순조1년) "신유사옥"이라는 천주교도의 처형을 대대적으로 단행한 주요한 원인의 하나를 거기에서 찾을 수 있다. 또한 한국의 천주교는 대체로 하류계층 또는 비집권계층 사이에 주로 전파되었을 뿐 아니라, 당시의 선교사와 한국 신도들이 의식적이든 무의식적이든 외세의 침입을 유도하는 역할을 했다는 것도 한국정부가 천주교를 탄압하게 만든 요인이 되었다.

청국장 발표중 첨가물에 의한 점질물의 물성적 특성 변화

이혜경,김성호,정낙현,임무현 대구대학교 과학기술연구소 1996 科學技術硏究 Vol.3 No.1

In order to study on the changes in the viscous substance by the additivies during the chungkookiang fermentation, amount of viscous substance, viscosity, rheological properties and organoleptic test of chungkookjang were carried out during fermentation periodically. The amount of the viscous substance was formed 1.31% by addition: of 3% M.S.G., 1.78% by addition of 5% sucrose, 1.80% by addition of 10% foxtail mil-let and when m;ixture(foxtail millet 1011o, red pepper 1%, garlic 1%, salt 3%, M.S.G. 3%)was added, viscous substance showed the highest amount with 1.92%. When blank was showed 1.147cp, viscosity was 3.206cp by addition of 3% M.S.G., 1.168cp by addition of 5% sucrose, 1.172cp by addition of 10% foxtail millet. When the fermentation proceeded for 72hours, hardness and brittleness were gradually decreased. Intensity of chewiness increased in the order of mix < foxtail millet < sucrose < blank. Chungkookjang sample added both 3% M.S.G. and 5% sucrose were good results and mixture sample(soybean 8291o, foxtail millet 10%, red pepper 1%, garlic 1%, salt 3%, M.S.G. 3%) was the best result with regards to the rheological and sensory evaluation.

忠南地域 屠畜豚의 肺病變으로부터 分離한 Actinobacillus pleuropneumoniae의 生物學的 및 免疫學的 特性

이종훈,장경수,장치훈,김일택,정용성,김귀현,전무형 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

An epidemiologic study on pleuropneumonia in the slaughter pigs(Chonan and Asan area, Chungnam province, Korea) during the period of January 1994 through December 1995 was conducted. Isolation of A. pleuropneumoniae was attempted in 425 pigs with pneumonic lesions. Biochemical properties, antimicrobial susceptibility, serotypes and pathogenicity of A. pleuropneumoniae isolates were investigated. In addition, outer membrane protein(OMP) of the isolates were extracted to determine its properties and immunogenicity in both mice and piglets. Of 3,395 slaughter pigs, pleuropneumonia was observed in 425 pigs(10.6%). A. pleuropneumoniae was isolated from 22 pigs(5.2%) out of 425 pigs with pneumonic lesions. The biochemical properties of all isolates were same as those of reference A. pleuropneumoniae strain. Among 22 isolates, 9, 1 and 12 isolates were serovar 2, 3 and 5, respectively. The results of antimicrobial susceptibility test revealed that the isolates showed high susceptibility to ciprofloxacin and cephalothin, moderate susceptibility to amikacin, gentamicin, kanamycin and streptomycin, and low susceptibility to erythromycin, tylosin and sulfadimethoxin. The isolates were varied in pathogenicity to mice. Median lethal dose of LE9402(serovar 2) and LE9511(serovar 5) were 9.2×10^7CFU and 2.8×10^7CFU, respectively. Specific pneumonic lesions were observed from the infected mice with clinical signs. Bacteria recovery rate was high in the lung, but low in heart blood and tracheas. Serovar 2 was found to be more pathogenic than serovar 5 in guinea pig. Mortality on guinea pigs inoculated with serovar 2(5.4×10^8 - 5.4×10^6CFU) abd serovar 5(2.8×10^8 - 2.8×10^6CFU) was 20-40% and 40-80%, respectively. A severe hemorrhagic lesions and focal pneumonic lesions were observed from dead guinea pigs. Bacteria recovery rate was relatively higher in the lung than that of other organs. In the SDS-PAGE analysis, OMP-enriched fractions of both isolates and reference strains contain common peptide bands equivalent to molecular weight of 17, 27, 42, 52 and 95Kd. In addition to common peptide bands, the bands which are specific to each isolate were also observed. The profiles of Sephadex G25 fractions showed 3 major peaks. The common peptide bands which were observed by SDS-PAGE of the crude OMPs were found i the peaks 1 and 2. The OMPs extracted from serovar 2(LE9402) and serovar 5(LE9511) provided high level of protection in mice(70-80%) and pigs(100%). All animals inoculated with OMPs were seroconverted, showing micro-agglutination titer of 640 to 1280.