항암제 젬시타빈의 경구용 제제 개발을 위한 전략수립

임지호,황지숙,이경록,이은주,조정원 충남대학교 약학대학 의약품개발연구소 2011 藥學論文集 Vol.26 No.-

교원의 교원능력개발평가 결과, 인구학적 특성과 전문성 인식의 관계

박지혜,이경란,문은주 이화여자대학교 교육과학연구소 2015 교육과학연구 Vol.46 No.4

This study aimed to provide useful information by investigating the relationships between the results of teacher evaluation for professional development, teachers’ demographic characteristics, and their perception of expertise. Among those who participated in the survey asking teachers’ perception of the 2014 teacher evaluation for professional development, the data from 1,622 teachers in the upper and lower limits of one standard deviation of teacher peer evaluation and student satisfaction were used. Study findings were as follows. First, statistically significant and positive correlations existed between teacher evaluation results and teachers’perception of expertise. Second, female teachers, those whose career spanned 5-15 years, elementary teachers perceived their expertise higher than those of male teachers, those whose careers did not span 5-15 years, and middle and high school teachers. Third, mean scores of expertise perception of teachers who had high scores on peer evaluation and student satisfaction were higher than those of other groups. Last, providing information to parents and appropriate evaluation were the key factors distinguishing those who had high scores on teacher evaluation and student satisfaction from those had high scores on teacher evaluation and low scores on student satisfaction. In addition, providing information to parents was the key factor differentiating those who had high scores on teacher evaluation and student satisfaction from those who had low scores on both teacher evaluation and student satisfaction. The significance of these study results was discussed along with limitations and suggestions for future research studies.

국내 의료종사자에서 HHV-8의 항체양성률에 대한 연구

주우철,최용준,박재은,이혜명,이진수,정문현,김수미,문지혜 대한감염학회 2008 감염과 화학요법 Vol.40 No.4

HHV-8 virus is known to be associated with Kaposi's sarcoma (KS) in HIV seropositive patients and its seroprevalence has geographic difference, In South Korea, incidence of KS is low not only in general population but also in HIV patients compared to other countries, It is speculated that low seroprevalence of HHV-8 has contributed to the low incidence of KS in South Korea. We examined the seroprevalence of anti HHV-8 IgG of HIV seronegative health care workers in one University hospital. Enzyme-linked immunosorbent assay(ELISA) was used for diagnosis. One person (0.6% 1/164) was seropositive, six were equivocal (3.7%,6/164) and 157 people were seronegative (95.73%, 157/164). This study revealed that seroprevalence of HHV-8 in general population was. low in South Korea. Further studies are needed to be carried out to evaluate the low HHV-8 seroprevalence in Korea.

장기간 보관한 멸균물품의 오염 상태에 관한 연구

주홍순,조순덕,정재심,신동분,임바올라,노은지,이선희,송영미,최정화,백병윤,김미나 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.1

마이크로니들의 형태 및 적용방법이 약물의 피부 투과에 미치는 영향

임지호,이경록,이은주,조정원 충남대학교 약학대학 의약품개발연구소 2012 藥學論文集 Vol.27 No.-

The purpose of this study is to develop the microneedle using biodegradable and biocompatible polymer and to pioneer the new route of drug delivery through the research to apply the most desirable administration form of small molecules, peptides, proteins, genes, biological products including vaccines. Various biocompatible microneedles were manufactured. To apply drug to microneedle, drug formulation using ethylene vinyl acetate patch or polyacryl acid gel was developed. Drug permeation into rat skin based on the application method of patch or gel with microneedle was studied using Franz diffusion cell system. In vitro drug permeation results showed that the permeation by the application of hollow microneedle was not increased compared with solid microneedle. When G60 or G60*2 microneedle was used, the permeated amount of calcein was increased compared to when solid microneedle was used. The permeated amount of lidocaine HCl in 12 hr was increased when microneedle was used was increased. Skin irritation followed by microneedle showed there was little difference in the decrease of redness after microneedle application based on application time.

유아교육기관에서의목공놀이활성화를위한프로그램개발

손지현,정은주 서울여자대학교 2007 아동연구 Vol.13 No.-

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요양병원 환자분류체계 개발

이지윤,윤주영,김정회,송성희,주지수,김은경 대한간호학회 간호행정학회 2008 간호행정학회지 Vol.14 No.3

Purpose: To develop the patient classification system based on the resource utilization for reimbursement of long-term care hospitals in Korea. Method: Health Insurance Review & Assessment Service (HIRA) conducted a survey in July 2006 that included 2,899 patients from 35 long-term care hospitals. To calculate resource utilization, we measured care time of direct care staff (physicians, nursing personnel, physical and occupational therapists, social workers). The survey of patient characteristics included ADL, cognitive and behavioral status, diseases and treatments. Major category criteria was developed by modified delphi method from 9 experts. Each category was divided into 2-3 groups by ADL using tree regression. Relative resource use was expressed as a case mix index (CMI) calculated as a proportion of mean resource use. Result: This patient classification system composed of 6 major categories (ultra high medical care, high medical care, medium medical care, behavioral problem, impaired cognition and reduced physical function) and 11 subgroups by ADL score. The differences of CMI between groups were statistically significant (p<.0001). Homogeneity of groups was examined by total coefficient of variation (CV) of CMI. The range of CV was 29.68-40.77%. Conclusions: This patient classification system is feasible for reimbursement of long-term care hospitals.

식이섬유가 고콜레스테롤혈증 흰쥐의 지질농도에 미치는 영향

김명주,장주연,이미경,박지윤,박은미 한국식품영양학회 1999 韓國食品營養學會誌 Vol.12 No.1

서울시 남녀 청소년이 지각한 부모-자녀 관계가 또래 관계에 미치는 영향에 관한 연구

최지은,신용주 동덕여자대학교 2002 생활과학연구 Vol.7 No.-

The purpose of this study was to investigate the effects of the perceived relationships of the adolescents with their parent on their peer relationships. The data were collected from 385 male and female high school students in Seoul through the questionnaire method. The instruments used for this study were the Parent Bonding Instrument(PBI) and the Index of Peer Relations(IPR). The data were analyzed by the frequencies, percentiles, means, standard deviations, Cronbach α, t-tests, oneway ANOVA, Pearson`s correlations and stepwise regression, using SPSS WIN 10.0 program package. Major results of the study were as follows: 1. An analysis of data revealed that degrees the relationships of the respondents with their parents and peer were higher than moderate. 2. The adolescents` peer relationship was affected by father`s occupations, family structures, parents` marital status and the economic status of the family. 3. The stepwise regression analysis yielded the results that relationship father`s caring(β=-.364), parents` marital status(β=.150) and economic status of family(β=.130) were significant factors in explaining the adolescents` peer relationship. Based on the results of the study, needs for effective father education and enhancement of stable marital relationships were addressed.

고등학교 토론 단원 교수ㆍ학습의 비판적 분석

김지현,전은주 부산대학교 사범대학 과학교육연구소 2012 교사교육연구 Vol.51 No.2

이 연구에서는 고등학교 국어 교과서의 토론 단원 통합 방식, 토론 지식의 설명 방식, 학습 활동의 타당성, 평가의 타당성 등에 대하여 비판적으로 분석하였다. 현재 국어과 교과서의 토론 단원 구성 방식을 ‘통합교육’이라는 측면에서 살펴보면, 토론 단원은 듣기, 말하기 영역의 통합과 여기에 더하여 읽기 영역이 통합된 것이 전부이다. 국어 능력의 총체적인 발달과 효율적 교수-학습을 위해, 쓰기와 문학과의 영역 통합도 가능하며, 말하기 또는 듣기 영역 내에서도 다른 성취 기준과의 통합도 가능하기에 보다 통합적으로 단원을 구성할 필요가 있다. 교과서 토론 단원에서 토론 지식을 설명하는 방법은 크게 ‘설명형’과 ‘요약형’으로 구분 가능한데, 대부분의 검정 교과서들이 ‘요약형’으로 제시함으로써 토론 지식을 단순히 정보 차원의 암기대상으로 다루는 문제점이 있었다. 이 논문에서는 교과서의 토론 단원에서 논제 분석과 토론의 유형과 절차 등 이해가 필요한 부분은 자세하게 ‘설명형’으로 제시하고 토론의 개념, 논제의 종류, 토론 참여자의 역할 등은 간략하게 ‘요약형’으로 제시하는 ‘혼합형’으로 제시하는 방법을 제안하였다. 이 연구에서는 토론 단원에 제시된 학습 활동의 타당성을, 교육과정에 제시되어 있는 여섯 가지 내용 요소를 기준으로 분석하였다. 분석 결과, 여섯 가지 내용 요소가 유기적으로 연결되어야 한다는 점, 활동이 정보 확인 차원에 머무르지 않고 실제적으로 학생들의 토론 능력을 향상할 수 있도록 활동을 구성해야 한다는 점, 학습자의 수준을 고려하여 충분히 상세하게 안내해야 한다는 점 등을 지적하였다. 이 밖에 이 연구에서는 교과서 토론 단원에 제시되어 있는 토론 평가 기준이 타당한가를, 평가 범주, 방식, 내용의 타당성을 중심으로 분석하고 그 문제점과 개선 방안을 제안하였다. This research critically analyzed the integration of the debate unit, explanations about debate knowledge, validity of learning activities and validity of assessment for high school. In terms of the integrated education for debate unit of Korean textbooks, the current debate unit is based merely on the integration of listening, speaking and reading. Integration of writing and literature is possible as well as that of listening and speaking. Besides, integrating other achievement standards under the same language skill is also possible. The way to describe the knowledge in debate consists of explanatory and summarizing types. Most approved textbooks employes summarizing type and regards the debate knowledge as what should be memorized. However, this study suggests that analysis of the discussion topic, types and procedures of the debate should be explained in detail (explanatory type), while the concept of debate, types of issues, and the role of participants should be given briefly in summary (summarizing type). The validity of learning activities in debate unit was analyzed on the basis of the six key elements of the curriculum. The authors pointed out that the six key elements should be organically connected, the activities should be organized practically in order to improve the debate ability of the learners, and detailed information should be provided with consideration of the learners’ level. Finally, the validity of debate assessment criteria provided in the debate unit of the textbooks was analyzed in terms of assessment categories, assessment methods and the validity of the contents.