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김미나,장성률,김미야,배종면,Kim, Mi Na,Jang, Sungryul,Kim, Mi Ya,Bae, Jong-Myon 제주대학교 의과학연구소 2020 The Journal of Medicine and Life Science Vol.17 No.2
Jeju Province has unique geographical and climatologic characteristics compared with other areas in Korea. Thus it needs to evaluate the status of nationwide notifiable infectious diseases(NND) continuously. The aim was to conduct a descriptive study for NNDs in Jeju Province, 2001~2019. The source of data was on the Infectious Disease Statistics System operated by Centers for Diseases Control & Prevention in Korea between 1 September 2001 and 31 August 2019. When calculating the proportion of the sum of years showing a higher incidence in Jeju province than nationwide divided by the sum of comparing years, the NDD with the proportion of the sum of years over 75% in 2001~2019 included varicella and syphilis. The results support significant evidence to plan strategies and distribute community resources for the control and prevention of NND in Jeju Province, Korea.
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김미나,조옥희,차경숙,Kim, Mi-Na,Cho, Ok-Hee,Cha, Kyeong-Sook 한국가정간호학회 2015 가정간호학회지 Vol.22 No.1
Purpose: This study aimed to determine the levels of burnout, self-efficacy, intention to stay, and organizational citizenship behavior (OCB) among nurses in small- and medium-sized hospitals, and factors related to nurses' OCB. Methods: A targeted sampling method was adopted, whereby 185 clinical nurses employed at 1 of 4 hospitals were enrolled in the study. OCB was measured with a tool developed by Podsaoff et al. Associated factors, including nurses' general characteristics, burnout, self-efficacy, and intention to stay, were measured using a structured survey. Data were analyzed by frequencies, t-test, ANOVA, Duncan's multiple test, Pearson Correlation Coefficient and multiple stepwise regression. Results: Levels of OCB in nurses was on average 3.52 on a scale of 1 to 5, exhibiting a positive correlation with self-efficacy and intention to stay, and a negative correlation with burnout. The final related factors were self-efficacy, burnout and intention to stay with a predictive and explanatory power of 52% for OCB. Conclusion: To increase the level of OCB of nurses, an environment in which such behavior is encouraged needs to be established by introducing measures related to administrative support and task efficiency that reduces mental burnout, while increasing self-efficacy and intention to stay.
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김미나,손상용,Long-Hai Cui,신호정,허훈,한상욱 대한위암학회 2017 Journal of gastric cancer Vol.17 No.2
Our preliminary results indicate that intraoperative vascular imaging using the ICG fluorescence technique may be helpful for robotic or laparoscopic pylorus-preserving gastrectomy.
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김미나,김현숙,김자경,김범경,김승업,박준용,김도영,안상훈,한광협 대한의학회 2016 Journal of Korean medical science Vol.31 No.9
Hepatitis C virus core antigen (HCV Ag) is a recently developed marker of hepatitis C virus (HCV) infection. We investigated the clinical utility of the new HCV Ag assay for prediction of treatment response in HCV infection. We analyzed serum from 92 patients with HCV infection who had been treated with pegylated interferon and ribavirin. HCV Ag levels were determined at baseline in all enrolled patients and at week 4 in 15 patients. Baseline HCV Ag levels showed good correlations with HCV RNA (r = 0.79, P < 0.001). Mean HCV Ag levels at baseline were significantly lower in patients with a sustained virologic response (SVR) than in those with a non SVR (relapse plus non responder) based on HCV RNA analysis (2.8 log10fmol/L vs. 3.27 log10fmol/L, P = 0.023). Monitoring of the viral kinetics by determination of HCV RNA and HCV Ag levels resulted in similarly shaped curves. Patients with undetectable HCV Ag levels at week 4 had a 92.3% probability of achieving SVR based on HCV RNA assay results. The HCV Ag assay may be used as a supplement for predicting treatment response in HCV infection, but not as an alternative to the HCV RNA assay.
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김미나,조은숙,김미야,배종면,Kim, Mi Na,Cho, Eun Suk,Kim, Mi Ya,Bae, Jong-Myon 제주대학교 의과학연구소 2018 The Journal of Medicine and Life Science Vol.15 No.2
Jejudo has unique geographical and climatologic characteristics compared with other areas in Korea. The aim was to evaluate differences of the nationwide notifiable infectious diseases (NND) occurred in Jejudo, 2011~2018. The source of data was on the Infectious Disease Statistics System operated by Centers for Diseases Control & Prevention in Korea between 1 January 2001 and 30 September 2018. After calculating the proportion of sum of years showing a higher incidence in Jejudo than nationwide divided by sum of comparing years(PSYH), authors defined the infectious diseases for control in Jejudo (IDCJ) with PSYH over 75%. In addition, the infectious diseases showing increasing trends during recent 2 years(2015~2018) were defined as sudden increase Infectious diseases for control (SIDCJ). IDCJ in 2001~2018 included 3 NNDs such as chicken pox, syphilis, and Streptococcus pneumoniae. The results support main evidences to plan strategies and distribute community resources for control and prevention of NNDs in Jejudo, Korea.
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다중 PCR법으로 진단한 Verotoxin 생성 Escherichia coli O157:H7 출혈성 장염인 영아 1예
김미나,조해선,조민철,노신애,김경모 대한임상미생물학회 2010 Annals of clinical microbiology Vol.13 No.2
Enterohemorrhagic Escherichia coli (EHEC) is an important cause of bloody diarrhea in children, but is considered to be rare in infants. Herein, a case of infant hemorrhagic colitis of verotoxin-producing E. coli O157:H7 diagnosed by multiplex PCR is reported. A nine-month-old boy was admitted to our hospital with bloody diarrhea for the previous two days. Multiplex PCR using SeeplexⓇ Diarrhea ACE Detection Kit (Seegene, Seoul, Korea) was directly applied to the stool specimens. Amplified bands specific for verotoxin,O157, and H7 indicated the presence of O157:H7 EHEC. The stool specimens were inoculated on sorbitol-MacConkey agar (SMA) and tryptic soy broth containing mitomycin C (TSB-M). Colorless colonies on sorbitol-MacConkey agar were O157-positive. TSB-M enrichment cultures of the stool specimen and the isolates were positive for verotoxin according to an enzyme immunoassay (EIA). The prepared ingredients of baby foods for the patient including ground meat, chopped carrot, chopped cabbage, and white rice porridge showed no EHEC on TSB-M and SMA. The patient’s parents and three-year-old sister did not recently have any gastrointestinal symptoms. Cefdinir was administered for one day and was ceased after diagnosis of EHEC colitis. The stool culture and verotoxin assay were negative on the second day of hospitalization. Application of multiplex PCR and verotoxin EIA directly to diarrheal stool warrants the rapid diagnosis and appropriate treatment of EHEC colitis. (Korean J Clin Microbiol 2010;13:85-89) 장출형성 대장균(EHEC)는 소아연령에서 혈성설사를 일으키는 중요한 원인균이지만, 1세 미만 영아에서는 드물다. 저자들은 지역사회 획득성 장염의 원인균을 진단하는 다중 PCR로 verotoxin 양성 E. coli O157:H7에 의한 출혈성 장염을 진단하여 보고하고자 한다. 환자는 9개월 된 남아로 이틀간의 혈변을 주소로 내원하였다. 설사변에 다중 PCR을 실시하여verotoxin, O157, H7 등에 특이적인 증폭산물을 얻어서 verotoxin 생성 E. coli O157:H7 감염이 추정되었다. Sorbitol-MacConkey 한천배지에 무색의 E. coli가 배양되었고, O157 항체와 반응시켰을 때 양성이었다. 대변검체를 mitomycin C가첨가된 배지에 증균하여 실시한 verotoxin 효소면역법에서 양성이었으며 분리된 균주 또한 verotoxin 양성으로 verotoxin 생성 E. coli O157:H7에 의한 EHEC로 최종진단하였다. 환아의 이유식 재료인 흰 쌀죽, 당근, 양배추, 소고기 간 것 등모두 배양 음성이었고, 환아의 가족인 부모와 3살된 누나는 장염 증상이 없었다. 환아는 입원 당일 E. coli O157:H7 장염으로 진단하여 cefdinir 투여를 하루 만에 중단하였으며, 입원 2일째부터 배양과 독소 검사는 음성으로 전환되었다. 향후직접검체에서 다양한 설사 원인균을 신속하게 검출할 수 있는 다중 PCR 검사가 EHEC의 조기 진단과 적절한 치료에유용할 것이다. [대한임상미생물학회지 2010;13:85-89]
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