유독물지정제도에 대한 유해화학물질관리자 및 전문가의 인식도 분석 연구

김미나,이승길,두용균,조삼래,최재욱,Kim,,Mi,Na,Lee,,Seung,Kil,Doo,,Yong,Kyoon,Cho,,Sam,Rae,Choi,,Jae-Wook 한국환경보건학회 2015 한국환경보건학회지 Vol.41 No.6

'스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

Objectives: Poisonous substances experts engage in policymaking regarding poisonous substances, whereas poisonous substances managers perform legal duties related to poisonous substances management systems at worksites. To understand and improve poisonous substances designation systems, it is necessary to distinguish the roles of these experts and managers. We further aimed to identify problems with poisonous substances appointment systems and provide basic data for their improvement by investigating the knowledge and recognition of the need for system improvement among managers and experts. Methods: To determine the $subjects^{\circ}{\emptyset}$ awareness of poisonous substances designation systems, a selfadministered questionnaire comprised of items on general characteristics and knowledge and recognition of the need for system improvement was issued. Data were analyzed via t-tests and ANOVA using SPSS v 16.0 Results: Regarding system comprehension, managers (n=213; mean 3.28, SD 0.63) significantly differed from experts (n=35; mean 4.08, SD 0.59) (P<0.001). No differences were found in recognition of need for improvement between managers (mean 3.11, SD 0.34) and experts (mean 3.24, SD 0.31). Significant differences in comprehension were found among managers by education level (P<0.05) and company size (P<0.05). Regarding industry type, comprehension was greater in the electrical/electronic and chemical/environmental industries compared to in other industries (P = 0.066). Comprehension was higher among those with five years or more of experience compared to those with less than five years. Regarding recognition of need for improvement, managers showed significant differences by company size (P<0.05). $Experts^{\circ}{\emptyset}$ comprehension showed no differences by general characteristics, while need for improvement differed according to work experience (P<0.001). Conclusion: The study found that the bigger the company size, the higher the level of comprehension by managers and the experts. In the case of both groups, where a higher comprehension of the poisonous substances designation system was evident, they recognized the necessity of its improvement.

조 크리스마스의 비극—트라우마와 정체성

김미나 21세기영어영문학회 2019 영어영문학21 Vol.32 No.4

This paper aims to illuminate the influence of trauma on the life of Joe Christmas, the main protagonist of William Faulkner's Light in August. The childhood trauma of Christmas is presented as flashbacks, and the writer tries to represent Christmas as a trauma victim who is in a continuous search for identity. His early traumatic event occurs in the orphanage when he accidentally witnesses the dietitian's intimate relationship, and she calls him “nigger bastard” in a rage. These words leads Christmas, who looks white, to experience an identity crisis. He tries to be white or black, but he fails to belong to either side. In the end, he repudiates the harsh dichotomy of Southern society and leads an alienated life. His tragic life, however, turns to catastrophe when he becomes a lover of Joanna Burden, a white spinster in her early forties, who is also a childhood trauma victim. When she forces him to act as a black man and to pray with her, Christmas kills her because her demand not only denies his 30 years of conflict but also triggers his racial and religious trauma and makes him outraged. He is also killed as a black man in the end.

심부전의 비약물 치료법

김미나 대한내과학회 2019 대한내과학회 추계학술대회 Vol.2019 No.2

세계가 한동네 ( 제 8 회 ) : 우수상 / 일본 동포 어린이에게

김미나 한국국어교육학회 1999 세계가 한동네 Vol.- No.-

Analytical and Clinical Validation of Six Commercial Middle East Respiratory Syndrome Coronavirus RNA Detection Kits Based on Real-Time Reverse-Transcription PCR

김미나,고영진,성문우,김재석,신보문 대한진단검사의학회 2016 Annals of Laboratory Medicine Vol.36 No.5

Background: During the 2015 outbreak of Middle East Respiratory Syndrome coronavirus (MERS-CoV), six different commercial MERS-CoV RNA detection kits based on real-time reverse-transcription polymerase chain reaction (rRT-PCR) were available in Korea. We performed analytical and clinical validations of these kits. Methods: PowerChek (Kogene Biotech, Korea), DiaPlexQ (SolGent, Korea), Anyplex (Seegene, Korea), AccuPower (Bioneer, Korea), LightMix (Roche Molecular Diagnostics, Switzerland), and UltraFast kits (Nanobiosys, Korea) were evaluated. Limits of detection (LOD) with 95% probability values were estimated by testing 16 replicates of upstream of the envelope gene (upE) and open reading frame 1a (ORF1a) RNA transcripts. Specificity was estimated by using 28 nasopharyngeal swabs that were positive for other respiratory viruses. Clinical sensitivity was evaluated by using 18 lower respiratory specimens. The sensitivity test panel and the high inhibition panel were composed of nine specimens each, including eight and six specimens that were positive for MERS-CoV, respectively. Results: The LODs for upE ranged from 21.88 to 263.03 copies/reaction, and those for ORF1a ranged from 6.92 to 128.82 copies/reaction. No cross-reactivity with other respiratory viruses was found. All six kits correctly identified 8 of 8 (100%) positive clinical specimens. Based on results from the high inhibition panel, PowerChek and AccuPower were the least sensitive to the presence of PCR inhibition. Conclusions: The overall sensitivity and specificity of all six assay systems were sufficient for diagnosing MERS-CoV infection. However, the analytical sensitivity and detection ability in specimens with PCR inhibition could be improved with the use of appropriate internal controls.

일개 의과대학생의 보완대체의학에 대한 인식 및 태도

김미나,성낙진,박기흠,정휘수,이동욱 동국대학교 의학연구소 2008 東國醫學 Vol.15 No.1

보완대체의학에 대한 사회전반적인 관심은 증가하고 있으나 일반인에게 객관적인 정보를 제공해야 할 의료 관계자들을 교육하는 체계적인 교육과정은 부족한 것이 현실이다. 앞으로 우리나라 의학을 책임질 의과대학생들을 대상으로 보완대체의학에 대한 통합 교육 전의 인식과 태도를 알아보고자 하였다. 2005년 10월 보완대체의학에 대한 의과대학 교육을 받은 적이 없는 일개 의과대학 의학과 전 학년 재학생 217명 중 설문에 참가한 173명을 대상으로 하였다. 자기 기입식 설문지를 이용하여 보완대체의학에 대한 인식도 23문항 및 태도 7문항과 응답자의 일반적 특성을 조사하였다. 인식도는 실무적용, 치료효과, 사회적 관심, 의사소통의 4영역으로 구분하였고, 태도는 응답자의 보완대체의학에 대한 경험과 습득 경로 등을 질문하였다. 보완대체의학의 인식도는 실무적용 2.93±0.70, 치료효과 3.09±0.34, 사회적 관심 3.66±0.56, 의사소통 3.60±0.73으로 실무적용을 제외한 나머지 영역은 긍정적인 태도를 보였다. 그러나 실무적용에서도 의료행위로의 개발 3.37±0.92 및 적용가능성3.29+0.97에 긍정적인 평가를 하였다. 태도 설문에서는 응답자의 92.5%가 보완대체의학을 들어보았으나 배운 경우는 19.7%에 불과하고 그 조차도 체계적인 과정이 아닌 경로가 대부분이었다. 치료는 61.3%가 의사와 상의하고 63.3%는 병원치료와 병행해야 한다고 응답하였다. 응답자의 일반적 특성에 따른 차이는 없었다. 의과대학생은 보완대체의학에 대한 교육과정을 받지 않았음에도 높은 사회적인 관심을 잘 인지하고 있었다. 또한 그 내용과 가치에 대해 어느 정도 인정하고 의사소통의 필요성 및 의료행위로의 개발가능성에도 우호적인 태도를 보였다. 그러나 아직 정립되지 않은 보완대체의학을 독단으로 사용하기보다는 의료인의 조언을 얻어 기존의 현대의학과 병행하여 이용하는 것이 바람직하다고 하였고 의료행위로의 개발 및 적용 가능성에도 높은 관심을 보였다. There are growing interest in the Complementary and Alternative Medicine(CAM) in the entire society while few physicians are provided systematic education about the CAM. The purpose of this research is to find out the recognition and attitude toward the CAM of the medical students. This survey was performed on October 2005, for 173 students in the medical school who have never experienced the education about the CAM. Using the self-written type of questionnaire, it examined their recognition toward the CAM through 23 questions, their attitude with 7 questions. The recognition was classified into 4 areas such as application, therapeutic effect, social interest and communication. The recognition for the CAM showed that application was 2.93±0.70, therapeutic effect was 3.09±0.34, social interest was 3.66±0.56 and was 3.60±0.73, all indicating the positive attitude except for application. However, application also showed the positive evaluation in the development possibility 3.37±0.92 and applicable possibility 3.29±0.97 as the medical activities. The attitude questionnaire showed that 92.5% had ever heard about the CAM while the learned experience was only 19.7% and all of which were not acquired through the systemic curriculum. The medical students were aware well of the high social interests even though they have not formally received any education courses of the CAM. In addition, they showed positive attitude about its value and contents, the possible development as the medical activities and necessary communications. However, most of them didn't recognize the CAM as an independent medicine.

위식도역류질환과 인후두역류질환의 약물 요법에 대한 최신지견

김미나,김주성,Kim,,Mi-Na,Kim,,Joo-Sung 대한기관식도과학회 2010 大韓氣管食道科學會誌 Vol.16 No.2

Gastroesophageal reflux disease (GERD) is a common disorder caused by the reflux of gastric contents into the esophagus. According to the recent classification, GERD can elicit esophageal and extraesophageal syndromes. Laryngopharyngeal reflux (LPR) is defined as laryngeal symptoms with laryngeal inflammation caused by the acid reflux. The prevalence of GERD and LPR is increasing during the past decades in Korea and management of GERD and LPR is a challenging issue in clinical practice. Proton pump inhibitor is the most effective drug in the treatment of GERD. Most patients with LPR are given a 2-month trial of a proton pump inhibitor (PPI), however, there is still little evidence on the diagnosis or the treatment of LPR. During the last years concern have been raised regarding the risk of averse events related to long-term use of PPI. We review the recent update on medical treatment of GERD/LPR.

지역사회 당뇨병 유병자와 비유병자의 심근경색증 및 뇌졸중 조기증상과 대처방안 인지도 비교: 성향점수매칭분석

김미나,이영훈,김남호 한국보건행정학회 2020 보건행정학회지 Vol.30 No.3

Background: We determined the differences in awareness of myocardial infarction and stroke according to the presence or absence of diabetes mellitus in the community. Methods: The 2018 Community Health Survey identified 20,812 people with diabetes mellitus aged 40–79 years. Using 1:1 matching by propensity score, 20,812 people without diabetes mellitus but with similar sociodemographic characteristics were selected as a comparison. Outcome variables were awareness of early symptoms of myocardial infarction and stroke and awareness of coping strategies in case of occurrence. Results: There was no significant difference between nondiabetic and diabetic people in terms of recognizing all early symptoms of myocardial infarction (nondiabetic, 42.7%; diabetic, 43.0%; p=0.43) and stroke (nondiabetic, 49.4%; diabetic, 49.4%; p=0.91). In addition, no significant difference was found between nondiabetic and diabetic people in the proportion of knowing correct emergency response to myocardial infarction (nondiabetic, 84.6%; diabetic, 84.4%; p=0.56) and stroke (nondiabetic, 81.3%; diabetic, 81.4%; p=0.77). Conclusion: Since people with diabetes are at greater risk of cardiovascular disease than the general public, it is important to lower the risk of disability and death by improving their awareness of early symptoms and correct emergency response to myocardial infarction and stroke.

다중 PCR법으로 진단한 Verotoxin 생성 Escherichia coli O157:H7 출혈성 장염인 영아 1예

김미나,조해선,조민철,노신애,김경모 대한임상미생물학회 2010 Annals of clinical microbiology Vol.13 No.2

Enterohemorrhagic Escherichia coli (EHEC) is an important cause of bloody diarrhea in children, but is considered to be rare in infants. Herein, a case of infant hemorrhagic colitis of verotoxin-producing E. coli O157:H7 diagnosed by multiplex PCR is reported. A nine-month-old boy was admitted to our hospital with bloody diarrhea for the previous two days. Multiplex PCR using SeeplexⓇ Diarrhea ACE Detection Kit (Seegene, Seoul, Korea) was directly applied to the stool specimens. Amplified bands specific for verotoxin,O157, and H7 indicated the presence of O157:H7 EHEC. The stool specimens were inoculated on sorbitol-MacConkey agar (SMA) and tryptic soy broth containing mitomycin C (TSB-M). Colorless colonies on sorbitol-MacConkey agar were O157-positive. TSB-M enrichment cultures of the stool specimen and the isolates were positive for verotoxin according to an enzyme immunoassay (EIA). The prepared ingredients of baby foods for the patient including ground meat, chopped carrot, chopped cabbage, and white rice porridge showed no EHEC on TSB-M and SMA. The patient's parents and three-year-old sister did not recently have any gastrointestinal symptoms. Cefdinir was administered for one day and was ceased after diagnosis of EHEC colitis. The stool culture and verotoxin assay were negative on the second day of hospitalization. Application of multiplex PCR and verotoxin EIA directly to diarrheal stool warrants the rapid diagnosis and appropriate treatment of EHEC colitis. (Korean J Clin Microbiol 2010;13:85-89) 장출형성 대장균(EHEC)는 소아연령에서 혈성설사를 일으키는 중요한 원인균이지만, 1세 미만 영아에서는 드물다. 저자들은 지역사회 획득성 장염의 원인균을 진단하는 다중 PCR로 verotoxin 양성 E. coli O157:H7에 의한 출혈성 장염을 진단하여 보고하고자 한다. 환자는 9개월 된 남아로 이틀간의 혈변을 주소로 내원하였다. 설사변에 다중 PCR을 실시하여verotoxin, O157, H7 등에 특이적인 증폭산물을 얻어서 verotoxin 생성 E. coli O157:H7 감염이 추정되었다. Sorbitol-MacConkey 한천배지에 무색의 E. coli가 배양되었고, O157 항체와 반응시켰을 때 양성이었다. 대변검체를 mitomycin C가첨가된 배지에 증균하여 실시한 verotoxin 효소면역법에서 양성이었으며 분리된 균주 또한 verotoxin 양성으로 verotoxin 생성 E. coli O157:H7에 의한 EHEC로 최종진단하였다. 환아의 이유식 재료인 흰 쌀죽, 당근, 양배추, 소고기 간 것 등모두 배양 음성이었고, 환아의 가족인 부모와 3살된 누나는 장염 증상이 없었다. 환아는 입원 당일 E. coli O157:H7 장염으로 진단하여 cefdinir 투여를 하루 만에 중단하였으며, 입원 2일째부터 배양과 독소 검사는 음성으로 전환되었다. 향후직접검체에서 다양한 설사 원인균을 신속하게 검출할 수 있는 다중 PCR 검사가 EHEC의 조기 진단과 적절한 치료에유용할 것이다. [대한임상미생물학회지 2010;13:85-89]

제주도 법정감염병 신고 현황: 2001~2019

김미나,장성률,김미야,배종면,Kim,,Mi,Na,Jang,,Sungryul,Kim,,Mi,Ya,Bae,,Jong-Myon 제주대학교 의과학연구소 2020 The Journal of Medicine and Life Science Vol.17 No.2

Jeju Province has unique geographical and climatologic characteristics compared with other areas in Korea. Thus it needs to evaluate the status of nationwide notifiable infectious diseases(NND) continuously. The aim was to conduct a descriptive study for NNDs in Jeju Province, 2001~2019. The source of data was on the Infectious Disease Statistics System operated by Centers for Diseases Control & Prevention in Korea between 1 September 2001 and 31 August 2019. When calculating the proportion of the sum of years showing a higher incidence in Jeju province than nationwide divided by the sum of comparing years, the NDD with the proportion of the sum of years over 75% in 2001~2019 included varicella and syphilis. The results support significant evidence to plan strategies and distribute community resources for the control and prevention of NND in Jeju Province, Korea.