리기다소나무의 毒性物質이 다른 植生에 미치는 影響

盧範鎭,吉奉燮 圓光大學校 基礎自然科學硏究所 1986 基礎科學硏究誌 Vol.5 No.1

Laboratory and field bioassay had performed to verify allelopathic effect of Pinus rigida ; seeding growth test of different species with aqueous extracts and rain leachate of the tree. The tests were focused to different concentration of the aqueous extracts and rain leachates, also different developmental stages of selected species. The longer time of extraction or the earlier of growing stage they have treated with the chemicals, the more inhibitory effects have obtained clearly in both laboratory and field bioassay. Allelochemicals of Pinus rigida were isolated and identified 8 phenolic compounds and 4 other by paper chromatography and HPLC.

全羅南北道 水域의 管束植物相과 그 分布

吉奉燮,尹敬源,盧範鎭,金昌煥 圓光大學校 基礎自然科學硏究所 1989 基礎科學硏究誌 Vol.8 No.3

全甫北 地域에 있는 6個 江과 고 流域에서 水生植物, 濕生植物과 水邊植物을 조사하였더니 水生植物은 57種類, 濕生植物은 74種類, 水邊植勃 123種類로 나타났다. 이들을 다시 分類하면 56科 145屬 190種 1亞種 27變種 1品種 總 219種類가 된다. 水生植物 中에는 抽水植物이 52.6%', 浮葉植物 21.7%, 沈水植物 19.3%, 浮水植物이 7%를 차지하고 있었다. 이들 中 頻度가 비교적 높은 식물은 검정말, 개구리밥, 노랑어리연꽃이었고 全般的으로 볼 때 優占襪은 검정말이었으나調査地點別로 差異가 있었다. 生物量(g/m^2)은 마름 2,935,5, 물잔디 1.050, 검정말 877.7, 물닭개비 847.1, 애기가래 806.9의 순으로 生量平均値를 기록했고, 乾量(g/m^2)으로는 마름225.4, 물잔디 90.3, 검정말 86.6, 대가래 78.6이었다. 調査地域 中에서 保護할 價値가 있는 곳은 耽津江이고, 植物은 여러곳에 나는 것으로 자라풀,노랑어리연꽃, 순채를 들 수 있다. To investigate the rearing environment of aquatic vascular plants and thechange of its spontaneity, field work was carried out in 6 rivers and theirdrainage basins located in Cholla-nam-but-do area. The flora was composed of 56 families, 145 genera, 190 species, 1 subspecies,27 varieties and 1 forms or 219 taxa; 57 species of hydrophytes, 74 of hygrophytes and 123 of waterside plants, Among hydrophytes emerged plant (E,52.6%), floating-leaved plant (FL,21.7%), submerged plant (S,19.3%) and freefloating planktonic plant (FP, 7%) were occupied, respectively. Dominant species was Hydrilla verlicillaia, but differed according to investigated. A significant place obseryed was Tamjin river and species to beprotected were Hydrocharis dubia, Nympkoides pellata and Braenia schreberi.

국제스포츠 정보 시스템의 현황 분석

육조영,윤찬호,김범수,노덕선,이무연,배진희,이승훈 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

Information has become a strategic tool with progress of sports science and sports technology. Demand on sports information is spreading to leisure, recreation, sociology, science of nutrition, psychology, sports medicine, sports therapy, prophylactic medicine, alternative medicine, sports industry and sports nature etc. if on line data base can be manipulated freely then acceleration and quality improvement of the study in this field can be effected and it is possible to gain new insight for receiving latest information But next problem is cost for use. For this reason this author summarized quick and effective on lline search points as follows: 1. Data base should be chosen with clear purpose for its use. Conduct prior investigation on contents and fee system of data base. With the same data base fee system may be differed depending on distributor therefore it is necessary to try different distributors at first as much as possible. 2. Prior to starting on line search prepare search method. If on line is started and then search method is checked than quickly telephone charge will go up. Search method should be prepared in advance by thinking sufficiently of what theme is to be searched. 3. Look for good advisor: lf there is no advisor nearby then the best thing is counselling with the person in charge for the distributor. If the result of search is stored at floppy disk by "downloading" then even after communication line is cut off it will be possible to print out anytime. 4. In this study the author explained about on-line search of lterature data line but recently it is possible to search overseas sports news or information on rate of victory or defeat of prfessional footbali etc. in real time. In Japan it is possible to search feature articles of Nihon Kesai or Asahi (except culture and sports column) by on-line. However in our country there are not many data bases in the field of sports and physical education which can be on-line searched. Our country belongs to up per level in the world in terms of study of sports science and technology and we are attracting attention from countries in Asia and from different parts of the world and the task facing us now is developing independent and unique data base for our country.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

개인 정보 보호에 대한 암 등록 사업의 해결 방안

박범정(Bum Jung Park),주형로(Hyung Rho Joo),박일석(Il-Seok Park),김진환(Jin-Whan Kim),노영수(Young-Soo Rho) 대한두경부종양학회 2007 대한두경부 종양학회지 Vol.23 No.2

Objectives and Background :Aims of this studies are to collect and analyze the lawful restriction against cancer registration and to suggest the model promoting the cancer registry. Materials and Methods :Total 16 countries, the members of OECD, including the U.S. are evaluated. the sta-tus of cancer registration of the evaluated countries are analyzed. The legislated laws, protect the individual’s information, of the evaluated countries are analyzed. The cases any registries were impaired with the law to protect privacy are searched and analyzed. Results :All of the evaluated countries have some kinds of privacy protecting laws. For cancer registration, 11 of 16 countries implement some lawful authorities. Some of countries have experienced restriction of registration by the law of protecting individual’s health data. All countries have performed cancer registry and 6 of 16 countries have nearly 100% population-based cancer registration. Conclusions :The cancer registry has to be the national effort. The informed consent of the data subjects and the permission of any special institutes are the difference to perform the registration. So, it is necessary to legi-slate any law supporting the cancer registration and establish any independent institutes to protect the individual’s health data and support the cancer registry.

한 대학병원에서 급성 폐색전증으로 진단된 환자들의 임상적 특성 및 예후

채진녕 ( Jin Nyeong Chae ),최원일 ( Won Il Choi ),박지혜 ( Jie Hae Park ),조병학 ( Byung Hak Rho ),김재범 ( Jae Bum Kim ) 대한결핵 및 호흡기학회 2010 Tuberculosis and Respiratory Diseases Vol.68 No.3

Background: Pulmonary embolism (PE) is a common clinical problem in the West that is associated with substantial morbidity and mortality. The diagnostic modality has been changed since 2001. This study retrospectively reviewed the PE mortality with the aim of identifying the risk factors associated with mortality since the multidetector computed tomography (MDCT) was introduced. Methods: We analyzed 105 patients with acute PE proven by multidetector CT or ventilation perfusion scan. The primary outcome measure was the all-cause mortality at 3 months. The prognostic effect of the baseline factors on survival was assessed by multivariate analysis. Results: The main risk factors were prolonged immobilization, stroke, cancer and obesity. Forty nine percent of patients had 3 or more risk factors. The overall mortality at 3 months was 18.1%. Multivariate analysis revealed low diastolic blood pressure and the existence of cancer to be independent factors significantly associated with mortality. Forty two PE patients were examined for the coagulation inhibitors. Four of these patients had a protein C deficiency (9.5%), and 11 had a protein S deficiency (26%). Conclusion: PE is an important clinical problem with a high mortality rate. Close monitoring may be necessary in patients with the risk factors.

膽囊 및 肝外膽道의 惡性 腫瘍

尹範容(Bum Yong Yoon),盧鉉富(Hyen Boo Rho),閔震植(Jin Sik Min),金春奎(Choon Kyu Kim) 대한외과학회 1975 Annals of Surgical Treatment and Research Vol.17 No.12

원전용 2차전지의 기술기준 분석에 관한 연구

박재범(Jea-Bum Park),태동현,노대석(Dae-Seok Rho),박성민(Seong-Min Park),박진엽(Jin-Yeop Park) 한국산학기술학회 2014 한국산학기술학회 학술대회 Vol.- No.-

기존의 원자력 발전소의 비상용 전원공급장치에서는 납축전지를 사용하고 있는데, 수명과 보수유지 측면 에서 많은 문제점을 안고 있어, 장수명과 우수한 성능을 가진 리튬이온전지로의 교체가 요구되고 있는 실 정이다. 따라서 본 논문에서는 원전용 리튬이온전지의 기술기준을 개발하기 위하여, 기존의 원전용 납축 전지 기술기준(KEPIC)과 리튬이온전지에 대한 국내외 기술기준을 분석 하였다.

두 개의 트랜스포머를 이용한 LCC 공진형 컨버터의 해석 및 설계

정영진(Young-Jin Jung),장두희(Doo-Hee Jang),노정욱(Chung-Wook Rho),한상규(Sang-Kyoo Han),홍성수(Sung-Soo Hong),이효범(Hyo-Bum Lee),오동성(Dong-Sung Oh) 전력전자학회 2009 전력전자학술대회 논문집 Vol.2009 No.1

LLC 컨버터는 누설인덕턴스를 공진인덕터로 사용하여 1차측 전류를 공진시키는 구조로써 누설인덕턴스와 자화인덕턴스의 비율이 작을수록 부하 및 입력전압의 변동에 따른 주파수 변동폭을 최소화 할 수 있다. 따라서 큰 누설 인덕턴스를 얻기 위해 주로 섹션보빈을 사용한다. 이는 큰 누설 인덕턴스를 얻을 수 있지만 트랜스포머의 발열 및 소모전력 상승의 원인이 된다. 본 논문에서는 두 개의 트랜스포머를 갖는 LLC 공진형 컨버터를 제안한다. 제안된 컨버터의 두 개의 트랜스포머는 스위칭 주기에 따라 공진인덕터와 트랜스포머로 각각 동작한다. 그러므로 제안된 컨버터는 공진인덕턴스와 자화인덕턴스의 비율이 1이하가 됨으로써 부하 및 입력전압의 변동에 따른 주파수 변동폭을 최소화한다. 따라서 큰 누설인덕턴스를 얻기 위해 섹션보빈의 사용이 필요 없으며, 트랜스포머의 전력소모를 저감시킬 수 있어 고효율 동작이 가능하다. 제안된 컨버터의 정상상태 해석 및 설계가이드를 제시하며, 80W급 LED 구동회로에 적용한 실험결과를 통해 제안된 컨버터의 우수성 및 타당성을 검증한다.

자궁내막증 환자와 정상 여성 간에 배란 전 난포액 및 복강액 내 PGF2α의 농도비교

윤태진,김용범,김학순,정은환,노재숙,지일운,민경준,신서규 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.11

Objective : The aim was to evaluate whether the differences of PG concentration in follicular and peritoneal fluid during preovulatory phase exist between the women with and without endometriosis. Material and Methods : Twenty-three patients with endometriosis, 8 were stage I-II and 15 were stage III-IV, and another 23 patients without endometriosis were undergone laparotomy during late follicular phase. Peritoneal fluid from 46 patients and follicular fluid from 42 patients were obtained, and these samples were analyzed double times for PGF2α, PGE2 and estradiol. Results : The mean level of PGF2α in the peritoneal fluid was significantly higher in the group with endometriosis than in the control(P=0.0293), especially more significant in stage I-II endometriosis. Although there was no significant difference of PGF2α concentration in the follicular fluid between the groups, the stage III-IV endometriosis group showed slightly higher PGF2α level than both the stage I-II group and the control(P=0.0604). And also, there was significant positive correlation with the level of PGF2α and estradiol in the follicular fluid only in the endometriosis group(r=0.4988, P=0.0154), not in the control. However, there was no difference in the level of PGE2 and estradiol in the peritoneal or follicular fluid between the groups. Conclusion : Some alterations of PGF2α level exist in the women with endometriosis. These are significantly higher PGF2α level in peritoneal fluid with mild endometriosis and slightly higher PGF2α levels in follicular fluid with extensive endometriosis during preovulatory phase, which suggest that PGF2α may play some roles in subfertility associated with endometriosis.