위절제술 환자의 표준진료지침 개발 및 적용 효과

김은희,김철규,이순교,김순덕,이혜옥,권정순,이경미,이민미,심순미,유용만,신종식,강은희,이상일,김병식,오성태,육정환,박수길 한국의료QA학회 2003 한국의료질향상학회지 Vol.10 No.2

Background : Gastric cancer is the most common malignant tumor in Korea. surgical operation is one of the major treatment modalities for gastric cancer patients. Therefore, gastrectomy is one of the most common procedures in General Surgery. There were variation in length of hospital stay and medical treatment for gastrectomy between three surgeons at Asan Medical Center. Clinical pathways have received considerable attention as a tool for recucing the medical practice variation, increasing the efficiency of care process, and improving the quality of care. The aim of this study was to evaluate the effect of a clinical pathway for gastrectomy in gastric cancer patients. Methods : The clinical pathway for gastrectomy was developed and implemented by a multidisciplinary group in Asan Medical Center. A computerized clinical pathway program was developed and revised after a pilot test. A total of 145 patients underwent gastrectomy by three surgeons at Asan Medical Center. We compared the length of hospital stay, patient satisfaction, and unplanned readmission rate between the pre-pathway group(n=67) and the post-pathway group(n=78). We also investigated the degree of satisfaction among the physicians and nurses who were main end-users of the clinical pathway. Results : The clinical pathway was applied to all target patients. The average length of hospital stay was shortened from 12.7days to 10.6days(p<0.01). The degree of patient satisfaction with the care process changed from 90.3% to 89.2% after the implementation of the clinical pathway, but the difference was of satistically significant(p=0.761). Unplanned readmission rate was 2.9% in the pre-pathway group. More than 90% of physicians and nurses answered that the clinical pathway had been a useful tool in their medical practice. Conclusions : The findings of the study demonstrated that implementation of the clinical pathway for gastrectomy produced substantial reduction in the length of hospital stay while improving the quality of patient outcomes. The computerized clinical pathway program can be used as one of the powerful patient management tools for reducing the practice variations and increasing the efficiency of care process in Korea hospital settings.

Aryloxyallylthiopyridazine 유도체 합성

권순경,김미경 德成女子大學校 藥學硏究所 2002 藥學論文誌 Vol.13 No.1

Allylthio group of the sulfur compounds of garlic oil plays an important role for prevention and treatment of hepatic diseases induced by toxic substances or carbon tetrachloride. Thus allylthio group as pharmacologically active group was introduced into pyridazine heterocycle ring. Aryloxyallylthiopyridazine derivatives were synthesized and their hepatoprotective activities were screened in rat. The activities of these compounds were weaker than alkoxyallylthiopyridazine derivatives, which exhibit a superior hepatprotective effect.

거대 난소 종양의 염전 1예

김미영,이해혁,유애리,박정희,이임순,정수호,고은석,레앙소팥,배동한,김태희,이권해 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.1

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수중액중의 중금속에 대한 녹차의 흡착성질

권이열,김미경,이동섭,홍순영,전혜옥 漢陽大學校 環境科學硏究所 1992 環境科學論文集 Vol.13 No.-

본 연구는 수용액중의 중금속에 대하여 녹차를 이용하여 흡착능을 고찰하였다. 실험에 사용된 녹차는 시판되는 "태평양화학 설록차(2번차)"를 40∼60mesh로 만들어 사용하였다. 각 중금속이온을 함유한 시료용액에 녹차를 첨가하여 흔든 다음, 원심분리해서 상등액중의 각 이온농도를 원자흡광광도계로 측정했다. 그 결과, 각 조건에서 녹차에 의한 중금속의 최대흡착율은 Cu(Ⅱ)는 65∼78%, Cd(Ⅱ)는 78∼82%, Pb(Ⅱ)는 82∼92%였으며, 반응초기 10분간에 최대흡착율의 90%가 일어났다. The adsorptivities of the green-tea particles on Pb(Ⅱ), Cd(Ⅱ) and Cu(Ⅱ) ions were examined by measurements of the adsorption percentage under various conditions, and the method to collect and remove the metallic ion in aqueous solutions were described. Each of 100ml sample solution of Pb(Ⅱ),Cd(Ⅱ) and Cu(Ⅱ) ions mixed with 2g of the green-tea under stirring for minutes. The solutions were then centrifuged, and the concentrations of Pb(Ⅱ), Cd(Ⅱ), and Cu(Ⅱ) ions in the supernatant solution were determined by the atomic absorption spectrometer. As the results, the adsorption equilibrium of Pb(Ⅱ), Cd(Ⅱ) and Cu(Ⅱ) ions were reached to equilibrium by shaking for about 30∼40minutes. Then adsorptivities were 84%, 79% and 65% respectively.

바나듐과 크롬의 쿠페론 착물의 전기화학적 행동의 차이

권영순,이상미,정미영,박소영 가톨릭대학교 자연과학연구소 2004 자연과학논문집 Vol.25 No.-

바나듐과 크롬의 쿠페론 착물의 전기화학적 행동을 아세트산 완충용액(pH 5.0)과 붕산염 완충용액(pH 9.5)에서 조사해 본 결과 크롬-쿠페론 착물의 환원봉우리전위(E_(ct)^(p))가 쿠페론의 봉우리전위(E₁^(p))보다 작다 (E_(ct)^(P) < E₁^(P)). 붕산염 완충용액에서 크롬-쿠페론계의 전도된 봉우리가 크게 나타나는 것은 E_(ct)^(P)와 E₁^(P)의 차이가 큰 때문인 것으로 생각된다 (ΔE = 0.40V). When the peak potentials of V-cupferron and Cr-cupferron complex compare at both buffer solution(pH 5.0 and pH 9.5), the peak potential of Cr-cupferron(E_(ct)^(P)) is smaller the peak potential of cupferron (E₁^(P)) at both buffer solution (E_(ct)^(p)) < E₁^(p)). The appearance of larger inverted peak of Cr-cupferron in borate buffer solution results from large difference of E_(ct)^(p) and E₁^(p) (ΔE=0.40 V).

간호중재분류체계(NIC)를 이용한 중환자실 간호중재 분석

권경남,장희정,황운순,김은주,이미경 영남이공대학 산업기술연구소 2000 産業技術硏究 Vol.12 No.-

The purpose of this research was to identify nursing interventions performed by the ICU nurses from 2 university hospital in Taegu. For this research, I used the Nursing Intervention questionnaire developed by the Iowa Intervention Project and translated by korean specialists and professor concerned to the same field. In order to obtain the data, a special group of professor, head nurse, charge nurse, researcher was instituted. The special group work validataed 205 nursing interventions with agreement of more than 50% becuse the NIC(433 nursing intervention) survey process was too time-consuming and not appropriate for all labels. The data were collected from June 1 to 30, 1999 and analysed with SAS program. The obtained results are as follows; (1) 94 interventions were performed at least daily. (2) The most frequently used nursing interventions were Parenteral Medication Administration, Aspiration Precautions, Pressure Ulcer Prevents, Positioning, Airway Management, Cough Enhancement in rank. In conclusion, this research using NIC has helped to figure out the component to the ICU care in korea. The use of this results will contribute to enhance quality assessment and improve standard of ICU nursing.

Allylthiopyridazine 유도체 합성 및 간보호 효과

권순경,이은방,김미경,박영남 德成女子大學校 藥學硏究所 1998 藥學論文誌 Vol.9 No.1

Allylthio group of the sulfur compounds of garlic oil plays an important role for prevention and treatment of hepatic diseases to be introduced by toxic substances or carbon tetrachloride. Thus allylthio group as a pharmacologically active group was introduced into pyridazine nucleus and a substituent such as halogen or alkoxy was also introduced into the para-posi-tion of allylthio group. Three allylthiopyridazine derivatives were synthesized and their hepatoprotective activities were screened in rat. Under the three compounds (6, 7, 8), 7 and 8 (methoxy-, ethoxy-substituent) are hepatoprotective, but 6 (chloro-substitu-ent) is negative.

2차원 스토커 소각론의 SNCR 탈질기술개발에 대한 수치해석

신미수,유승민,유재관,장동순,김동찬 충남대학교 환경문제연구소 2000 環境硏究 Vol.18 No.-

In this study was the stoker incinerator system with SNCR(Selective Non-Catalytic Reduction). While this system was favored with the view of the possibility of the reducing waste volume and recovery of waste heat, it also has a disadvantage, that is, the need for the second to treat dust, HCl, CO, etc. So far, even though a great deal of research had been done, the study on heat-flow analysis with reduction model and NO reduction with SNCR had not been investigated enough. The temperature distribution in the system and excess amount of oxygen influence the efficiency of NO reduction, resolution in the production, resolution in the production of NO at 1700K and the temperature range of 1200-1250K when the highest NOx reduction efficiency occurred. Hence, this study was focused to flow mixing pattern and NOx reduction efficiency as the flue gas velocity, NH3 injection velocity, particle size and particle density.

과학 교육에서 STS 수업모형의 적용효과에 대한 메타 분석

정미진,윤기순,권덕기 경북대학교 과학교육연구소 2008 科學敎育硏究誌 Vol.32 No.2

이 연구의 목적은 STS 과학교육에 대한 국내 연구의 동향을 분석하고 메타분석을 통해 STS 수업모형의 적용효과를 평가하는데 있다. 연구대상 논문은 1991년부터 2006년까지 출판된 석사학위 논문 104편과 과학교육 저널에 출판된 논문 78편을 포함한 총 180편이었다. STS 수업 모형의 효과 평가에 총 56편이 선정되었다. STS 수업 모형 적용 효과의 평균효과크기는 0.40이었다. 이 결과는 STS 수업은 학생들의 과학에 대한 태도, 과학 학업 성취도, 탐구능력, 환경에 대한 태도 및 환경에 대한 지식을 향상시키는데 전통적인 수업보다 긍정적인 효과가 있었음을 의미한다. STS 수업은 환경에 대한 태도의 증진에 가장 큰 평균효과 크기를 나타내었다. 그러므로, STS 수업에서 가장 좋은 효과를 얻기 위해서는 이러한 결과들을 반영하는 것이 필요할 것이다. 향후 STS 교육에 대한 전반적인 평가를 하기 위해서는 STS 수업 모형의 효과와 과학-기술-사회의 상호관계에 대한 교사와 학생들의 이해에 대한 연구 결과를 종합하는 것이 필요하다. The purposes of this study were to analyze the domestic research trend of the STS Education and to evaluate the application effects of STS teaching model by using Meta-analysis. The selected research articles were 180 articles including 104 of the master’s theses and 76 of science education journal articles published from 1991 to 2006. For the evaluation of the effects of STS teaching and learning model, 56 articles were selected finally. The mean effect size of the application effects of STS teaching and learning was 0.40. The result indicated that STS teaching had more positive effects than the traditional teaching on enhancing student's attitude for science, academic achievement in science, inquiry ability, attitude for environment and knowledge for environment. Especially, it had shown the most positive effects on improvement in the attitude for environment. Therefore, it might be better to reflect these results for the best effect of STS teaching. To assess STS education on the whole, it is necessary to synthesize the effects of STS teaching and learning model and the results of the study on teachers’ and students’ understanding about the interrelation of science, technology and society.

초기 저광도 광중합이 레진 수복물의 결합강도에 미치는 영향에 관한 연구

한미란,권순원,김종수 대한소아치과학회 2001 大韓小兒齒科學會誌 Vol.28 No.1

레진 수복에서 초기에 저광도로 중합하여 레진의 유동성을 허용함으로써 중합시 내부응력을 상쇄하며, 다시 고광도로 중합하여 레진의 물성도 유지할 수 있는 방법이 시도되고 있어, 초기 저광도 중합이 상아질과의 결합 강도와 레진의 미세경도에 미치는 영향을 알아보고자 하였다. 소의 건전한 하악 전치 20개를 3개의 절편으로 절단하여 각 군에 배분하고 상아질면에 레진을 충전한 후, 1군은 450mW/㎠의 광도로 40초간, II군은 300 mW/㎠와 600 mW/㎠의 광도로 각각 20초씩, III군은 250 mW/㎠ 와 450 mW/㎠에서 각각 20초씩 광중합하여 전단 결합 강도를 측정하였고, 직경 5.0mm깊이 2.0mm레진 시편을 제작하여 상, 하면 중앙에서 Vickers 미세 경도를 측정하였다. 전단 결합 강도는 초기 저광도 중합군의 평균이 다소 높았으나 각 군간 통계학적 유의한 차이는 없었으며, 미세 경도는 상, 하면 모두에서 각 군간 통계학적으로 유의한 차이는 보이지 않았다. Recently some studies have shown that low light intensity followed by final cure at high light intensity may result in a smaller marginal gap and may be no negative effect on material properties. The purpose of this study was to evaluate the influence of the initial cure with low intensity on the shear bond strength of dentin and the microhardness of composite resin. Twenty intact bovine teeth were prepared for shear bond strength test and each tooth sectioned to three specimens. The specimens were randomly divided into three groups according to the light intensity and curing time as follows ; Group I. 450mmW/㎠ 40sec Group II . 300mmW/㎠ 20sec and 600mmW/㎠ 20sec Group III . 250mmW/㎠ 20sec and 450mmW/㎠ 20sec Samples of each group were restored with light-cured composite resin after dentin bonding and then the shear bond strength of each specimen were measured using universal testing machine. Ten resin specimens per group were prepared. After 24 hours, the Vickers microhardness value was measured at the top and bottom surfaces. The result are as follows; 1.Mean value of low initial intensity groups(II, III) were higher than the control group( I ) in shear bond strength, but no significant difference could be found. 2.No significant difference could be found between three groups in microhardness.