심첨부 비후 심근증에서 심근 내 미세 관상동맥의 혈류 예비력 평가 : 경흉부 도플러 심초음파를 이용한 연구 Study Using Transthoracic Doppler Echocardiography

윤호중,박철수,신재원,임상현,조은주,정해억,전희경,오용석,정욱성,김재형,최규보,홍순조 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.3

소목(Caesalpina sappan L.) 추출물의 항균성과 김치숙성에 미치는 효과

이신호,최우정,조옥기,손수정 대구효성가톨릭대학교 식품과학연구소 1997 식품과학지 Vol.9 No.-

김치의 숙성을 지연시킬수 있는 천연물질을 검색하기 위하여 소목 ethanol추출물의 항균력을 조사하고 김치제조에 응용할 수 있는 가능성을 검토하기 위하여 소목 추출물 1%를 김치 제조시 첨가하여 10℃에서 숙성시키면서 그 변화를 관찰하였다. 소목 ethanol추출물은 유산균 4종류 7균주에 대하여 성장억제 효과를 나타내었으며 생균수 측정시에도 시험균주 모두에 대해 공히 1~4 log cycle의 항균효과를 나타내었다. 김치 숙성 중 소목 첨가구의 경우 숙성 기간동안 대조구에 비해 pH와 산도가 다소 높은 경항을 나타내었다. 소목 추출물을 첨가한 김치의 관능검사는 대조구와 첨가구간의 유의적 차이를 보이지 않았으며 sour taste의 경우에는 대조구에 비해 첨가구의 수치가 더 낮은 경향을 나타내었다. Antimicrobial effect of ethanol extracts of Caesalpina sappan Linne and its effects on kimchi fermentation were investigated. Antimicrobial activities of the extract against 4 kinds of lactic acid bacteria isolated from kimchi, such as Lactobacillus plantarum, Lactobacillus sake. Leuconostoc mesenteroides and Pedicoccus pentosaceus showed 1~4 log_(10) reduction during incubation for 12 hours. The growth of tested lactic acid bacteria did not occur in Caesalpina sappan Linne containing modified MRS broth except L. plantarum HSU02 and L. mesenteroides HSU14. The pH of kimchi containing 1% of Caesalpina sappan Linne extracts was higher than that of control but titratable acidity, total bacteria and Lactobacilli were lower than that of control during fermentation for 25 days at 10℃. Sour taste of Caesalpina sappan Linne containing kimchi was more weak than that of control. Sensory score of flavor and overall acceptability did not show significant difference between Caesalpina sappan Linne containing kimchi and control during fermentation.

전격성 경과를 취한 만성 호산구성 폐렴 환자 1예

윤호상,진춘조,유광하,이상엽,이수인,정상만,김선두,이순제,이길도,전혜정 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Chronic eosinophilic pneumonia(CEP) is a rare disease of unknown etiology characterized by chronic infiltration of the lung with eosinophils. It presents with profound systemic symptoms comprising fever, night sweats, weight loss, dyspnea and blood eosinophilia with nonsegmental air-space consolidation confined to the outer third of the lung, the "photographic negative of pulmonary edema". Histopathologic features of chronic eosinophilic pneumonia are intraalveolar and interstitial infiltrations with eosinophils, histiocytes, giant cells, scattered lymphocytes and plasma cells. Glucocorticoid therapy cause prompt resolution of symptoms as well as disappearans of blood eosinophils, elevated serum Ig E levels and the roentgenographic lesions. Infrequent radiographic findings include nodular infiltrates, consolidations, cavitations, atelectasis and pleural effusions. Deaths from CEP although rare, have been reported, but the majorities of CEP have benign courses and do not need a therapy with ventilator. We report a case of chronic eosinophilic pneumonia, which had a sudden course associated with diffuse pneumonic consolidations on the both lung and bilateral pleural effusion.

코칭 관리의 과정 모델 분석

육조영,김희수,윤찬호 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.5

The purpose of this study is to examine the process of 'coaching(administration)' .For that purpose, this study brought in the concept of the management process (VanderZwaag, H.J.) and the administrative process(Hodgkinson, C.) and examined the process model of 'coaching(administration)' . As the result of this study, the process of coaching (administration)' was characterized as follows. 1. The process model of 'coaching(administration)' consists of philosophy, planning, organizing, managing and valuating. 2. At the stage of philosophy and planning, the policy of 'coaching(administration)' is made. 3. At the stage of organizing and managing, the policy of 'coaching(administration)' is implemented and the process of 'coaching(administration)' goes on toward the purpose effectively. 4. The last stage of process (valuating) feeds back to the stage of philosophy. 5. The stage of philosophy has the possibility for changing the direction of process through the consideration of value.

하위범주화를 이용한 한국어 내포문의 해석과 사전의 표현

李相祚,金昇浩,林修延 慶北大學校 1990 論文集 Vol.49 No.-

This study presents the informations of dictionary for the analysis of Korean embedded sentence using subcategorization of Korean verb. This informations control gapping components in embedded sentence (VP, NP, Relative) and generate all possible parse trees of input sentences by parser based on KPSG(Korean Phrase Structure Grammar).

갑상선 세포에서 전사보조활성인자인 CBP와 CIITA의 인터페론-감마 활성 부위에 대한 조절 : CBP and CIITA on GAS(Interferon- γ Activated Site)-Mediated Transcription in Thyroid Cells

채수흥,홍우정,김군순,조영석,김도희,김현진,구본정,송민호,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 2001 충남의대잡지 Vol.28 No.1

Background : In the previous stuides, we identified that the interferon-r activated sequence (GAS) in the 5-flanking region of rat ICAM-1 gene is major element for interferon-r-inducible expression of the gene in rat thyroid cells, FRTL-5. We here, investigated the role of transcriptional coactivators, CBP(CREB binding protein) and CⅡTA (class Ⅱ transactivator) in the modulation of the activity of GAS which could interacts with signal transducers and activators of transcription-1 and 3 (STAT1 and STAT3). Methods : The expression of CBP RNA and protein were quantitated in FRTL-5 after stimulation with interferon-r (IFN-r), thyroid stimulating hormone (TSH), forskolin and methimazole. Direct association of CBP with STAT were analyzed by immunoprecipitation. The transcriptional roles of CBP and CⅡTA in the regulation of GAS were assessed by the cotransfection with their expression vectors with reporters; 5-deletion constructs of rat ICAM-1 promoter or 8xGAS-luc constructs, into FRTL-5 thyroid cells. Results : The level of CBP RNA and protein were not changed by the treatment with TSH, IFN-r, forskolin and methimazole in FRTL-5, FRT and BRL liver cells. The CBP could be directly associated with STAT1. Furthermore, the overexpression of CBP significantly increases the both promoter activities; rat ICAM-1 gene promoter which has GAS element and 8xGAS-luc cassette constructs. However, the cotransfection of CⅡTA decreased the constitutive and CBP-mediated transactivation of rat ICAM-1 promoter and 8xGAS-luc cassette constructs. Conclusion : We identified that the two tanscriptional coactivators; CBP and CⅡTA has differential roles in the regulation of transcriptional activity of GAS drived promoter. CBP increases the GAS activity through the direct binding with STAT1, but CⅡTA inhibited the CBP-mediated transactivation of GAS activity.

정신분열병과 Glutathione S-Transferase M1유전자 다형성

배치운,조자현,김연주,김태석,김정진,이창욱,이수정,전태연,이철,백인호 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.5

Objectives : This study aimed to test the possible association between Glutathione S-Transferase Ml gene (GSTMl) variants and schizophrenia. Methods : One hundred and eleven inpatients with schizophrenia and 130 healthy controls were recruited. Genotyping was performed by polymerase chain reaction-based method. Results : The GSTMl null genotype was significantly more frequent in patients with schizophrenia than in controls (p=0.014, odd ratio=1.93, 95% confidence interva1=1.115-3.351), while GSTMl genotype vahants were not associated with either tardive dyskinesia (TD) or total Abnormal Involuntary Movement Scale (AIMS) scores. Conclusion : The present study suggests that the GSTMl polymorphism may confer susceptibility to the development of schizophrenia but not to TD, at least in Korean population.

관상동맥질환자에서 경흉부 도플러 심초음파를 이용한 좌심실 확장기 기능의 평가 : 좌심실 확장기 장애 형태에 따른 분류

전희경,윤호중,유기동,박지원,전두수,정욱성,채장성,김재형,최규보,홍순조 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.1

김치저장성 향상을 위한 동결방법이 배추조직의 물성변화에 미치는 영향

양진한,박소희,유진현,임호수,조재선,황성연 한국식생활문화학회 2003 韓國食生活文化學會誌 Vol.18 No.2

김치를 10˚C에서 8일간 숙성시켜 산도 0.6~0.7%로 숙성된 김치를 -70˚C와 -20˚C로 냉동하며 -20˚C에서 저장하면서 배추 조직의 elasticity, hardness, 세포 조직의 변화, 드립양을 실험한 결과는 다음과 같다. -70˚C에서 급속 동결한 것과 -20˚C에서 완만 동결한 냉동 김치 중 배추조직의 elasticity는 냉동 저장 15일까지 감소하다 일정하게 유지되었고 hardness는 거의 변화가 없었으며 냉동 방법에 따른 변화도 거의 나타나지 않았다. 투과 전자현미경으로 관찰한 결과 control의 경우 세포벽이 매우 두꺼우며 세포의 모양들이 잘 보존되어 잇는 것을 볼 수 있었고 -20˚C로 냉동 처리하여 해동시킨 세포벽들은 많이 손상되어 있음을 볼 수 있었으며 -70˚C로 급속 냉동시료의 경우 세포벽의 손상 정도가 -20˚C로 냉동 처리한 시료보다 덜 파괴되어 있음을 볼 수 있었다.한편 냉동 저장기간 동안 드립의 손실량의 변화는 -70˚C로 냉동 처리한 시료의 드립양은 3~4%정도로 -20˚C로 냉동 처리한 시료의 5~6%에 비해 적은 것을 알 수 있었다. This study was conducted to investigate the effect of freezing methods, show freezing at -20℃ and rapid freezing at -70℃, on physical properties of Chinese cabbage in frozen Kimchi during storage at -20℃. Elasticity of midrib of Chinese cabbage in frozen Kimchi was decreased until 15 days and did not changed thereafter during storage at -20℃, Hardness of that was not changed during storage. Those results of elasticity and hardness of slow frozen sample are similar to rapid frozen sample. By the morphological observation through transmission electron microscope, more of cellular structure of Chinese cabbage in slow frozen was destructed than that of rapid frozen sample. Drip loss was more in slow frozen sample than that in rapid one.

한국과 일본 고등학생의 학교 스트레스 비교 분석 : Focusing on School Students in Korea and Japan

洪光植,嶋田洋德,朱昊秀,趙誠培 全州敎育大學校 初等敎育硏究所 1998 初等敎育硏究 Vol.9 No.-

Recently, a wide variety of maladaptation, such as school refusal or mental disorder, has remarkably increased in high school students in Korea and Japan. The increase of stressful events which students experience in their school life is regarded as one of the causes of this phenomenon. The previous study which attempted to clarify the school stress process(Shimada et al., 1993, 1995, 1996) developed the school stress(Emotional Response, Psychological Response, School Maladjustment, Irrational Beliefs Scale) scales for high school students to assess both the frequency and the averseness of events which students encounter in their daily school life. 659 Korean and 211 Japanese high school students completed the stress process scale. The main results were as follows. (a) Korean students evaluated the Emotional Response Scale at a higher level than Japanese did. (b) Korean students evaluated all the Psychological Response Scales at a higher level than Japanese did. (c) Japanese student evaluated School Maladjustment scales (study evaluation, club activities evaluation) at a higher than Koreans did. But at the school evaluation scale is the response diametrically opposed. (d) Korean students evaluated all the Irrational Beliefs Scales than Japanese did. In summary, Korean students felt the events in high school were more stressful than Japanese did.