당뇨병환자에서 뇨증 Fibronectin농도의 증가에 관한 연구

한승범,조준승,손건영,서성문,박근용,조성래,박규영,박정모,이인규,여준기 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

Plasma fibronectin is an α₂-glyoprotein, which is produced by vascular endothelial cells. Raised level of plasma fibronectin has been observed in diabetic patients particularly in the presence of microvascular complications. However, no available data exist about urine level of this glycoprotein in diabetic patients. We measured urine fibronectin level by ELISA methods in 54 diabetic patients who have microvascular comlications or not. The following results were obtained. 1) Urine fibronectin level(㎍/g creatinine) in diabetic group(1740.0±678.0) is increased compaired with those in normal control group(471.0±59.0). but this results were not significantly different among two groups(P>0.05). 2) Urine fibronectin level(㎍/g creatinine) was significantly increased in patients with nephropathy (6188.0±3144.0) compared with those in normal control group(471.0±59.0) and patients without nephropathy(645.0±251.0)(P<0.001). 3) There were a significant correlation between BUN, creatinine, creatinine clearance, 24hr urine total protein and urine fibronectin level in diabetic patients. Our data suggest that urine fibronectin excretion level might be used as a sensitive guide for diabectic nephropathy.

Rifampicin에 의한 것으로 추정되는 위막성 대장염1예

김수현,이은우,정종혁,문승현,김동한,양혁승,오영상,김호동,김도현,박혁,박정환,박경옥,이영직 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Pseudomembranous colitis, caused by altering the normal colonic flora and allowing the multiplication of Clostridium difficile, is an deleterious adverse effect of antibiotics. But it is rarely reported by rifampicin. Rifampicin is one of the first line drug in the treatment of tuberculosis and many patients are exposed to its potential adverse effects. We experienced a patient that had abdominal discomfort and hematochezia due to pseudomembranous colitis after receiving antituberculous medication, and which was probably caused by rifampicin. A 82 years old man was admitted with abdominal discomfort and hematochezia for one week. On the past history he had been diagnosed as endobronchial tuberculosis about 4 months ago. Colonoscopy revealed multiple discrete whitish mucosal lesion on rectosigmoid colon, and histologic findings were consistent with pseudomembranous colitis. The antituberculous agents were discontinued and vancomycin was administered. The patient's symptoms were resolved within several days. There was no recurrence after reinstitution of the antituberculous agents excluding rifampicin. We report here on a case of pseudomembranous colitis probably due to rifampicin.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

관동맥 재개통 후 QTc간격분산의 감소 : 정량적으로 측정한 심근 허혈의 호전 정도와의 연관성 Relationships with the Quantitative Degree of Improvement in Myocardial Ischemia

박상선,최기준,남기병,이철환,홍멸기,박성욱,박승정,신중우,문대혁,김유호 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

Lactobacillus plantarum을 接種한 옥수수와 수수 Silage 製造 試驗

文勝式,朴成振,鄭錫龍,宋瑛敏 진주산업대학교 농업기술연구소 1989 農業技術硏究所報 Vol.2 No.-

유산균 접종이 옥수수와 수수silage의 품질에 미치는 영향을 조사할 목적으로 L. plantarum을 대조구는 접종하지 않았고 처리구는 2×10 exp(8), 4×10 exp(8) 및 6×10 exp(8)cfu, kg^-1(fresh forage) 수준으로 접종하여 조제한 silage의 일반성분, pH 및 유기산 함량을 비교한 결과는 다음과 같다. 1. crude protein, crude ash, NDF, ADF 및 hemicellulose 함량은 접종수준이 증가할수록 높았고 moisture 및 NFE 함량은 낮았다. 2. 접종수준이 증가할수록 lactic acid와 total acid 함량은 증가한 반면 acetic acid함량과 pH는 낮았다. 3. 옥수수 silage에 비하여 수수silage에서 L. plantarum의 접종효과가 높았다. The objective of this thesis is to investigate the effects of lactic acid bacterium inoculation on the qualities of corn and sorghum silages. The control group was not inoculated : the treated group was inoculated with Lactobacillus plantarum of the levels of 2×10 exp (8), 4×10 exp(8) and 6×10 exp(8) cfu. Kg^-1(fresh forage). The chemical components, pH and organic acid contents of the developed silages were measured and compared. The results obtained are as follows : 1. As the level of inoculation was higher, the contents of crude protein, crude ash, NDF, ADF and hemicellulose became larger, but the contents of moisture and NFE became smaller. 2. As the level of inoculation was higher, the contents of lactic acid and total acid became larger, but the acetic acid content and the pH became smaller. 3. The inoculation effect of L. plantarum was greater in the sorghum silage than in the corn silage.

통상정보학의 실용성 제고를 위한 연구방향

박승락,박문서 한국통상정보학회 1999 통상정보연구 Vol.1 No.2

연구방법론의 관점에서 통상정보학은 매우 다양한 방법으로 접근이 가능하며, 특히 정보통신기술을 적극적으로 활용할 수 있기 때문에 항상 새로운 접근 방법이 출현할 수 있다. 또한, 정보기술의 급격한 발전으로 국제전자상거래가 급격히 확산되고 있는 현 시점에서 수출기업의 단순한 무역자동화 수준을 벗어난 국제간 B to B 전자상거래의 전략적 활용방안에 대한 연구가 필요한 때이다. 이에 본 연구에서는 통상정보학의 실용성 제고를 위한 구체적인 연구방향으로써 전략 정보시스템과 조직이론을 가미한 조직간 정보시스템 이론을 제시함으로써, 조직간의 전략적 연계를 통한 전략적 통합정보시스템 구축전략을 제시하고자 하였다. 이를 통하여 정보화의 이점을 통상학 분야에 도입하고, 전략적으로 활용 가치가 있는 정보를 생산, 저장, 유통 및 활용함으로써 학술적 비용발생을 최소화하며, 기업의 이윤발생을 촉진함으로써 국가경쟁력의 확보에 기여할 수 있도록 하는 것이 통상정보학의 궁극적인 지향 목표이다.

마약길항제의 방출 제어형 제제 (제2보) : 나록손 이식제제의 생체적합성 및 약물속도론적 평가 Biocompatibility and Pharmacokinetics of Naloxone Implant

문미란,박주애,이승진,김형국,김길수 梨花女子大學校 藥學硏究所 1995 藥學硏究論文集 Vol.- No.5

For the effective administration of narcotic antagonist, the application of sustained release implantable systems with biodegradable polyphosphazene was examined. Using poly[(diethyl glutamate)-co-(ethyl glycinate) phosphazene]. the implantable devices containing naloxone hydrochloride were prepared and in vivo implantation studies were carried out subcutaneously in rat and rabbit with this preparation for the biocompatibility and pharmacokinetics. The histological finding in rats at initial time period was the inflammation that occurred focally around the implants, but they were showed subsequent mild and limited chronic inflammations and the irreversible changes such as necrosis and degeneration of the muscle or connective tissues were not observed. Therefore the placebo and naloxone implants are considered to be biocompatible formulations histologically. In pharmacokinetic studies, the release of naloxone from the naloxone implants into blood plasma was maintained in 192 hours, but the initial burst effect was observed. If this problem was solved, the application for the narcotic antagonist sustained release systems can be expected.

産卵鷄에 대한 練炭灰添加給與 效果에 關한 硏究

朴成振,文勝式,鄭場龍 진주산업대학교 1982 論文集 Vol.20 No.-

This experiment was conducted to investigate the effect of Briquette ash treatment on egg production rate, egg weight, feed conversion and egg quality with date obtained from 100 pieces egg type fowls Babcock (B 380, 230days-age) fed and allotted 5 treatments at the rate of 0%(C), 0.5%(T_1) 1.0%(T_2), 1.5%(T_3)AND 2.0%(T_4) during the experiment period of 119 days from May 21, 1982 to September 20, the same year ar Department of Animal science, Jin Ju Agricultural and Forestry Junior Technical College. The results obtained are summarized as follows; 1. Average egg weight at each experiment plot was 62.21g(T_2) 61.62g(T_3), 60.88g(T_4), 60.42(T_1) and 60.04g(C), but the difference was not significant. Feed conversion at each experiment plot was 2.52(T_2) 2.60(T_3), 2.65(C) and 2.67(T_4). 2. Average egg production rate at each experiment plot was 82.02%(T_2) 81.85%(C) 81.43%(C), 79.41%(T_3) and 78.23(T_4), but the difference was not significant. 3. Weight of egg yolk and albumen were higher at fed with the treated Briquette ash plot than that without Briquette ash plot, and weight of egg shell and thickness were not significant.

모험스포츠 참가자의 몰입경험과 자아효능감의 관계

문태영,박승환 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.6

The purpose of this study is to examine closely the relation of absorption experience and self efficacy for a participant in the adventurous sports. For the purpose of attaining this aim, it surveyed absorption experience, self efficacy and the like as to the participation in adventurous sports. In terms of the statistical methods used aiming to analyze data, it carried out frequency and percentage, t-test and one-way ANOVA, correlation, depending on the purpose of analysis. As for collecting data, it carried out self-administrated questionnaire targeting 250 women who did take part in the adventurous sports, while conducting the survey from November 2002 to August 2003, but the conclusions, which were unveiled, utilizing the gathered data of total 232 persons except those whose response contents were decided to be insufficient, are as follows. First, in light of absorption experience as to demographic change factors, participants in the adventurous sports had high degree of absorption experience, and the higher level of the absorption experience was shown at a man than a woman, at an older person and at a participant than non-participant. Second, in terms of physical self efficacy as to demographic change factors, the participants in the adventurous sports did not show such a high physical self efficacy, and the higher level of the physical self efficacy was shown at a man than a woman, at an older person and at a participant than non-participant, and as for the general self efficacy, participants had high self efficacy, and the higher level of the general self efficacy was shown at an older person and at a participant than non-participant. Third, in the relation of absorption experience and self efficacy, it was shown to be high in the absorption experience, physical self efficacy and general self efficacy of participants in the adventurous sports.

糖蜜吸着 煉炭灰飼料의 添加가 肉鷄의 發育에 미치는 影響

朴成振,文勝式,宋瑛敏 진주산업대학교 1989 論文集 Vol.27 No.-

본 시험은 육용계(Arbor acres) 160수를 공시하여 당밀 흡착연탄재사료(Molasses-absorbed briquette ash feed : MBF)를 육계사료에 0, 2, 4 및 6% 수준으로 첨가하였을 때 사양성적, 도체율, 복강지방, 소화기관, 계분의 수분과 회분 및 경제성 등에 미치는 영향을 조사하기 위하여 실시하였다. 1. 종료시 체중과 증체량은 MBF첨가에 의해 개선되었고 그 경향은 2% 및 4% 구에서 크게 나타났다(P<0.05). 2. 사료효율은 2%구에서 가장 좋은 경향이었고 2%구와 6%구를 제외한 다른 구에서는 차이가 없었다(P>0.05) 3. 도체율과 복강지방은 각구에서 큰 차이가 없었다. 4. 소화기관의 중량 및 길이는 각구에서 큰 차이가 없었다. 5. 계분의 수분함량은 각구에서 비슷하였으나 회분함량은 첨가 수준이 높을수록 증가되었다. 6. 경제성 분석 결과는 2% 및 4%에서 양호한 편이었다. This experiment was performed to study the effects of addition levels 0, 2, 4 and 6% of molasses-absorbed briquette ash feed(MBF) on 180 broilers. On the growth, dressing percentage, abdominal fat, gastrointestinal tract, moisture and ash content in excreta and economics were investigated. The results are summarized as follows : 1. Final weight and weight gain were significantly higher in MBF added 2% and 4% group(P<0.05) 2. Feed efficiency was significantly(P<0.05) higher in 2% group and was not differences between other expect 2%, 6% group. 3. Dressing percentage and abdominal fat was not significantly each group. 4. Gastrointestinal tract weight and length was not significantly each group. 5. Moisture contents in excreta were didn't show significant differences between the each treatment group, but ash contents in excreta increases according to the increasing level of MBF. 6. Optimun level of maximum profit on economic analysis was found to be 2% and 4% group with broiler chicks.