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      • KCI등재

        가감청영탕(加減淸營湯)에 효과를 보인 열성 아토피 피부염 환자 6례 증례 보고

        서지혜,정창환,박선정,임소영,한수련,Seo, Ji-Hye,Jung, Chang?Hwan,Park, Seon-Jeong,Lim, So-Young,Han, Su-Ryun 대한한방안이비인후피부과학회 2014 한방안이비인후피부과학회지 Vol.27 No.3

        Objective : The purpose of this study is to investigate the effect of Gagamchengyoung-tang($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) for atopic dermatitis patients diagnosed as the febrile tendency. Method : This case study was done on 6 atopic patients with febrile tendency who have visited Korean Medicine Clinic from 2013.08.01. to 2014.04.30.. Gagamchengyoung-tang($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) was prescribed to all 6 patients and evaluated the symptom change through photographs and questionnaire. Objective SCORAD Index(OSI) was used to evaluate the objective symptom and VAS was used to evaluate the subjective change. Results & Conclusion : The Objective SCORAD index and VAS were decreased in all patients. The average OSI reduction score was 26.3. Most symptoms of 6 patients were improved. Gagamchengyoung-tang ($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) can be effective in patients who were diagnosed as febrile tendency.

      • KCI등재

        Production and Characterization of Enzymes Involved in Chitin Catabolic Cascade from a Bacterial Strain Isolated from Soil

        ( Ji Hyun Lee ),( Jeong In Lee ),( So Yeon Park ),( Yoo Kyeong Jang ),( You Bin Lim ),( Hye Yoon Lee ),( Young Min Jung ),( Hae Chang Lee ),( Jong Hwa Lee ),( Shaheen Amna ),( Jae Kweon Park ) 한국키틴키토산학회 2019 한국키틴키토산학회지 Vol.24 No.1

        The present study was aimed to isolate the bacteria producing chitinolytic enzymes including chitin deacetylase (CDA) from soil origin. About 24 bacteria were screened for their chitinolytic enzymes producing ability on the basis of colloidal chitin. Amongst one of the most potent isolates designated to JI-02 was further selected as the most prominent chitinolytic and CDAlike enzyme (CDA-X) producer based on the ability of deacetylation of an artificial substrate pNP-acetamilide. The maximum production of CDA-X in crude enzyme from JI-02 was observed in the presence of 1% colloidal chitin at 37°C and pH 6.4 after 120 h of incubation. Potent enzyme activity of CDA-X was determined toward pNP-acetamilide, demonstrating that optimal pH, temperature and ionic strength of the CDA-X were assessed to be 7.0, 52°C and 125 mM, respectively. Unexpectedly, Nacetylglucosamine (GlcNAc) was not fully converted by the action of CDA-X to glucosamine (GlcN) under the established conditions. Further study on enzyme activity toward chitin-oligosaccharides consisting of multi-N-acetylglucosamine (GlcNAc)n, n=2-5 may be necessary to elucidate the mode of action which requires the minimum size of (GlcNAc)n. However, our data suggest that CDA-X can convert chitin to chitosan with the maximum yield of approximately 0.08g/L during the fermentation of the strain in the presence of chitin. Furthermore, we found that crude enzyme showed the significant chitosanolytic activity. Taken together, our data suggest that the strain JI-02 may be a potential candidate as a particular strain for better understating of chitin catabolic pathway.

      • KCI등재후보

        무용전공별 척주만곡도 비교

        임혜자,권혜영,서지혜,이성노 韓國舞踊敎育學會 2003 韓國舞踊敎育學會誌 Vol.14 No.1

        The purpose of this study was to analyze the differences in the shape of the front, lateral, and rear sections of the spinal columns by dance majors. The results of the study are described below. First, with respect to the cervical spinal curvature of the lateral spinal column, there were a significantly differences between the general public and modern dance major person. Among other groups, however, there were no differences. Second, in the case of the thoracic spinal curvature, there were no significant differences between the general public and the people who major in Korean traditional dance. However, the measure of the thoracic curvature in modern dancers was greater than that found in ballerinas and Korean traditional dancers. Furthermore, the general public's thoracic spinal curvature was greater than the modern dancers'. Finally, there were no significant differences between modern dancers and the general public in the measure of their lumbar spinal curvature. Korean traditional dancers' lumbar spinal columns, however, were much more curved than the ballerinas'. In addition, modern dancers' lumbar spinal columns were much more curved than Korean traditional dancers'. Based on the results of the study, two recommendations can be proposed. First, training programs and practical courses for dance majors need to be improved simultaneously so that dancers can strengthen their abdominal muscles and increase their flexibility. Second, to avoid deterioration of backbone growth, the general public needs to build up their health through dancing or other exercise programs.

      • KCI등재후보

        국내 직업무용단의 운영실태 및 발전방안 모색

        임혜자,안지혜,이성노 韓國舞踊敎育學會 2004 韓國舞踊敎育學會誌 Vol.15 No.1

        With the observation that civic and provincial dance troupes are remarkably active in the sphere of dance in each region of Korea, the purpose of this study was to present a more reasonable plan for managing professional dance troupes. We undertook this study by examining the operational problems, and compensation issues of dance troupes. For this study, several professional dance troupes in Korea (five civic dance troupes, plus one national troupe: the UBC Ballet Troupe) were selected as subjects. The results of the study are as follows: Firstly, the management of professional dance troupes needs to be improved and in particular, the issue of salary is most urgent. Secondly, corporate bodies are opposed to the transformation of their troupes and suggested that if change is indeed needed that management of a troupe be entrusted to a nongovernmental organization within two years. Meanwhile, public dance troupes approved of the plan and desired that the system be implemented within one year. Thirdly, the management of the troupes should be given over to professional artists and specialist aligned with the troupes. Fourthly, public group members, especially women members firmly believed that their own group should be generally improved. They also believed that the expansion of production costs was the most urgent issue requiring attention In addition, troupe members estimated that the standard of their contribution to the development of the art was average, and they would leave the matter to the direction of the art director. In short, for the development of professional dance troupes, the present system of the dance troupes should be transformed to a civil and consigned management system operated by experts, and the terms of salary, living conditions and the problem of expanding production costs should all be ameliorated.

      • 원발성 후복막 점액낭샘암종 1예

        지준호,이화정,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

        Primary retroperitoneal mucinous cystadenocarcinoma is a very rare malignancy, and little is known concerning its Pathogenesis, optimal treatment, and prognosis. A 29-year-o1d pregnant woman (21 weeks) Presented with abdominal discomfort CA 19-9, CA 125, and CEA were normal Abdominal CT scanning revealed a 19x15x13 cm retropentoneal tumor Exploratory laparotomy and tumor excision were performed. Mucinous retropentoneal implants were removed as completely as possible Histologically, the tumor showed focal areas of capsular invasion, but free resection margins The uterus and both ovaries were normal in appearance No adjuvant therapy was pursued. Six months later, Peritoneal and bilateral ovarian metastases were discovered. Hence, we report the details of this case of primary retroperitoneal mucinous Cystadeno-carcinoma and present a review of the literature.

      • KCI등재

        하악 유구치 치근단 병소에 의해 변위된 계승 영구치의 맹출유도

        양수민,김재곤,백병주,양연미,한지혜 대한소아치과학회 2007 大韓小兒齒科學會誌 Vol.34 No.2

        적절히 치료받지 못한 유치의 치수 감염은 치근단 주위로 확산되고 그 치근단 병소는 계승 영구치의 조기 맹출, 법랑질의 저형성이나 저석회화, 발육정지 등의 합병증을 야기할 수 있다. 특히 유치의 치근단 감염은 계승치의 변위를 야기할 수 있으며, 계승 영구치배의 위치변화는 선행 유치의 치수변성으로 인한 것이 가장 많다. 본 증례보고는 하악 유구치의 치근단 병소에 의해 계승치가 변위된 경우로서, 증례 1은 하악 우측 유구치 하방의 치근단 낭에 의한 계승치의 변위가 관찰되어 유치 발치 및 조대술을 시행한 후 obturator를 장착하였고, 증례 2는 하악 우측 제2유구치 하방의 치근단 농양에 의한 계승치의 변위가 관찰되어 유치를 발거하고 공간유지장치를 장착하였다. 본 증례를 통하여 하악 유구치 치근단 병소에 의해 계승 영구치가 심한 변위을 나타낸 경우, 적절한 치료를 통해 계승 영구치의 적절한 맹출을 유도할 수 있었기에 보고하는 바이다. Primary teeth and the permanent successor must be understood as interdependent units, where each one of them interacts with and depends upon the other. The spread of pulpal inflammation in primary teeth to the periradicular tissues can lead to early eruption, enamel hypoplasia or hypocalcification, developmental arrest of permanent successor. Also the periapical inflammation cause permanent tooth displacement in various direction. We describe here two clinical cases of displaced permanent successor caused by periapical lesion of mandibular primary molar in children.

      • 비소세포 폐암종에서 Epidiermal growth factor receptor(EGFR)의 발현 양상

        임석호,이지혜,조현득,오미혜,김의한 순천향의학연구소 2008 Journal of Soonchunhyang Medical Science Vol.14 No.1

        배경: 비소세포 폐암종에서 epidermal growth factor receptor (EGFR)의 발현이 예후에 미치는 영향에 대해서는 아직 일치된 결론에 이르지 못하고 있으며, 비소세포 폐암종의 조직 병리학적 소견으로는 종양의 진행 및 예후에 대해 예측이 불가능하다. 이에 저자들은 종양의 EGFR 발현과 임상 및 병리학적 특징과의 관계를 관찰하였다. 재료 및 방법: 1990년부터 2004년까지 순천향 대학교 천안병원에서 수술로 절제된 95명 환자의 포르말린에 고정한 파라핀 포매 조직을 이용하여 EGFR 항체를 이용한 면역조직화착 검사를 시행하였으며 이의 결과를 환자의 임상양상과 병리학적 소견과 비교 분석하였다. 결과: EGFR 발현과 환자의 생존기간을 비롯한 성별, TNM 임상병기, TU댕기, N-병기와는 관련이 없었으나 조직학적 유형중 편평상피암종은 47예중 43예가 양성 반응을 보여 통계학적으로 의미 있는 상관관계를 보였다(p=0.005). 그 외에 성별, 조직학적 유형, TNM 임상병기, T-병기, N-병기중 어떠한 변수도 생존기간과의 연관성을 보이지 않았다. 결론: 비소세포 폐암종에서 EGFR의 발현은 환자의 생존기간 및 임상병리학적 소견과 유의한 상관관계를 보이지 않으므로 예후인자로서의 이용은 현재로선 불가능하여 좀 더 많은 증례를 통한 연구가 필요할 것으로 사료된다. Background: The prognostic role of epidermal growth factor receptor (EGFR) remains controversial in patients with non-small cell lung cancer (NSCLC). Histopathologic findings cannot adequately predict disease progression, so we investigated the reladonship between EGFR and clinicopathologic feature. Methods: Using immunohistochemical techniques, we retrospecdvely analyzed formalin-fixed, paraffin-embedded samples from 95 padents with resected pathological NSCLCs. Then, we correlated these data with padents' clinical outcome and pathologic finding. Results: No reladonship was found between EGFR overexpression and patient survival when the entire cohort was considered. Multivariate factors including gender, histologic type, TNM stage, T stage and N stage were not correlated to poor outcome. Also, no factors revealed correlation with EGFR overexpression except histologic type. Squamous cell carcinoma showed positive reaction in 43 out of 47 patients(p=0.005). Condusion: This result indicated that EGFR overexpression in NSCLC showed no reladonship with patients' survival. Therefore, EGFR overexpression could not be used as a poor prognostic marker.

      • KCI등재후보

        심상훈련이 재즈댄스 참여자의 동작수행에 미치는 영향

        서지혜,임혜자 韓國舞踊敎育學會 2003 韓國舞踊敎育學會誌 Vol.14 No.1

        This study was focused on analyzing the influence on movement performance conducted by general people who took part in a Jazz Dance class, and researched in order to examine the possibility of application of effective imagery training for Jazz Dance guiding. This study was done with 36general people who were taking a class in a Jazz Center in Daegu, selecting general people who have no experience in this kind of experiment, and divided into 4 groups, such as physical training group(n=9), imagery training group(n=9), imagery-physical training parallelism group(n=9) and a control group (n=9.) For the data analysis of the study, mixed-variance analysis; measurement repetition of between measurement time, and variance analysis of between training groups was used in order to analyze the effect of training group(4) x measurement time(2) of Jazz Dance on in terms of skill, art, music, and suitability. Moreover, for the ex post facto approval, the t-test method was used, so it was possible to test the differences of measurement time(2) of each types. The significant difference is p<0.05 The conclusions of this study are as follows: First, imagery training has an affirmative effect on movement performance of Jazz Dance Second, for the application of imagery training, detailed analysis of the performance is needed, and has to be checked whether the experiment participants have been improved and been better by the imagery training. Thus, if the possibility of application is acknowledged, tit's he most effctive way to mix the imagery and physical training Based on these conclusions, the study reached several proposals as follows: First, in the case of operating the imagery and physical training at the same time in order to reach the maximum level of imagery training, the various studies on to what extent the imagery and physical training should be applied must be accomplished. Second, the imagery training studies must be done by many researchers with the subject of not only dance major groups, but also general public groups.

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