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한국산 물두꺼비(Bufo stejnegeri : 무미목 , 두꺼비과)염색체의 인형성부위에 대한 개체간 및 개체내 변이
이혜영,박창신 한국유전학회 1989 Genes & Genomics Vol.11 No.3
The distribution of the nucleolus organizer regions (NORs) on the chromosomes of 10 individuals of Bufo stejnegeri (Anura, Bufonidae) was investigated by conventional and NORs-staining analysis. 1. Seven individuals exhibit one pair of NORs on the long arm of the chromosome pair 6 (standard form). 2. The one individual had a pericentric inversion on chromosome bearing NORs, whereby a large part of the NORs translocated in an telomeric position on the short arm. Therefore, a trace of original NORs remained an original terminal position on the long arm. Only one of the largest homologues had additional small NORs in the interstitial region of short arm. The possible explanation is the mechanism of translocation and segmentation (or fragmentation) in the NORs cluster (varied form I). 3. The two individuals exhibit inter- and intraindividual variation in number, position and size of the NORs. The mechanisms of these variation were explained by translocation and segmentation (or fragmentation) of NORs (varied form II).
슬골관절염 환자를 위한 타이치운동, 수중운동과 자조관리프로그램의 효과비교
이혜영,Lee Hea-Young 한국간호과학회 2006 Journal of Korean Academy of Nursing Vol.36 No.3
Purpose: This study was to compare the effects among Tai-Chi exercise, aquatic Exercise, and a self-help program for knee osteoarthritis patients on symptoms of arthritis, muscle strength, balance, and difficulty of performing activities. Method: There were 50 final subjects50. A non-equivalent pretest-posttest design was used. The collected data was analyzed using SPSS for Window. One-way ANOVA and Scheffe's multiple comparison test were used 8weeks after each program. Result: There were significant differences in joint pain(p=.000), stillness (p=.001), knee extensor peak torque(p=.006), knee flexor(p=.002), and difficult of performing activity (p=.000), but there was no significant difference in balance(p=.648). The Tai-Chi group was significantly different from the self-help group for knee extensor peak torque, knee flexor and stiffness on Scheffe's multiple comparison tests. In addition, the Tai Chi group or aquatic group were significantly different from the self-help group for difficulty of performing activities(p<0.05). Conclusion: There are significant differences in the effects of the nursing intervention among the three groups. The Tai Chi group and aquatic group were significantly different from the self-help group. However, it seems that Tai-chi exercise may be more suitable than aquatic exercise in osteoarthritis exercise programs. Further studies with a longitudinal study are necessary to confirm the longer exercise period.
김해 야생차와 운남 보이 쇄청모차의 항산화 활성 및 유용성분 함량 비교
이혜영,이병인,정영식,안범수,심두보,김종철,최송현 한국차학회 2023 한국차학회지 Vol.29 No.1
최근 국내에서 유행하는 운남 보이생차 중 고수차(古樹茶)는 고가에 유통되고 있지만 성분이나 효과가제대로 알려져 있지 않다. 본 연구는 김해지역 야생차를 운남 보이생차와 같은 제다법으로 제조하여 카페인, 카테킨, 유리아미노산, 갈산, 폴리페놀, 항산화능, 맛 분석 등의 성분분석을 통하여 보이생차의 대체재로서 김해지역 야생차의 가능성을 알아보고자 한다. 대부분의 성분분석에서 운남 모차가 평균적으로 조금 더 높은 성분함량을 나타냈으나 큰 차이가 없어 유의미하지 않았다. 그러나 아미노산 총량에서는 김해 모차가 평균 5% 정도높게 나타났고, 전자 혀를 통한 맛 분석에서는 신맛(AHS)을 제외한 4개의 맛센서 값에서 김해모차가 전체적으로 높은 값을 보였다. 김해 모차를 이용하여 다양한 풍미를 가지는 차를 제다하는 것이 가능할 것으로 보인다. 모든 성분에서 운남 보이차와 비슷한 결과를 보여준 대성동(T8) 야생차는 발효차에 적합한 모수로 육종하는 것을 통해 운남 보이 생차의 대체재로 활용 가능성이 높다고 사려된다.
이혜영 19세기영어권문학회 2002 19세기 영어권 문학 Vol.6 No.1
Hyeyoung LeeSince its publication Jane Eyre has been read as a psychological bildungsroman. And recently it is a trend to read it as a feminist bildungsroman. The purpose of this article is to analyze Jane Eyre as a Christian bildungsroman. To understand Jane Eyre fully, contextual approach is necessary. And if we consider the Christian background of 19th century England in reading Jane Eyre, many repressed meanings of the novel will surface.To read Jane Eyre from the Christian perspective is, first of all, to focus on the spiritual growth of Jane and Rochester. Both Jane and Rochester go through hardships and come to mature spiritually. The most important part of the spiritual maturity is to learn to put God's love before their ‘passionate' human love. This humility before God is the crucial part of the Christian wisdom. And the other indispensable learning for both of them is to admit the invisible hand of God guiding their lives. In this respect Jane Eyre belongs to the genre of governess novel which was popular in 19th century England and stressed the governing hand of God in human lives. The marriage of Jane and Rochester is one of the best examples of the ‘companionate marriages' in the history of the English novel. However, the happy and equal companionate union is possible only after the achievement of their spiritual equality, not just the economic, social or sexual equality.
장애인을 위한 재활간호프로그램이 근력, 유연성, 자기 효능감과 건강관련 삶의 질에 미치는 효과
이혜영,Lee Hea-Young 한국간호과학회 2006 Journal of Korean Academy of Nursing Vol.36 No.3
Purpose: The purpose of this study was to investigate the effects of a rehabilitation nursing program(RNP) for persons with disabilities. Method: a quasi-experimental pretest and post test study was used to examine the changes of patient's muscle strength, flexibility, self efficacy and health related quality of life at the completion of an 8-week education and physical exercise with a Thera-Band and Exercise Ball course. The subjects consisted of 40 adults who were disabled. Twenty-two experimental and 18 control subjects completed pre and post-test measures. Outcome variables were flexibility, hand grip, elbow flexor and extensor, knee flexor and extensor, self efficacy and quality of life. Independent t-test and ANCOVA were used to examine group differences by using SPSS 12.0 Result: Mean comparisons of the change scores revealed that the experimental group increased significantly in knee extremity flexor(p=0.035), extensor(p=0.039), flexibility(p=0.008), self efficacy(p=0.000), and quality of life(p=0.000). No significant group differences were found in each patient's hand grip, elbow flexor and extensor. Conclusion: RNP can improve lower extremity flexibility, muscle strength, self efficacy and health related quality of life in people with disabilities. The intervention to tailor exercise and education to the unique needs of the disability was suggested for further study.
이혜영,이금재 한국간호과학회 2008 Journal of Korean Academy of Nursing Vol.38 No.1
Purpose: This study was to determine whether the Sun-style 24 forms of Tai Chi exercise improve pain, stiffness, disability, knee joint motion, mobility, balance or falling. Method: Forty-six community-dwelling elderly subjects (mean age, 75.46±6.28) voluntarily participated in an intervention group of either 24 forms of Sun-style Tai Chi for 60 min, 2 times per week for 12 weeks or a control group. A non-equivalent pretest-posttest design was used. Independent t-test and ANCOVA were used to examine group differences by using SPSS12.0. Result: The experimental group had significantly less pain (F=7.60, p=.008) and stiffness (t=-3.19, p=.003) than the control group. Also there were significant improvements in knee joint motion on the right knee (t=2.44, p=.019), left knee (t=2.30, p=.026), rising time (F=8.03, p=.07), balance on the left single leg test (t=2.20, p=.033), and fear of falling (t=-2.33, p=.024) in the Tai Chi exercise group. No significant group differences were found in disability and falls efficacy. Conclusion: The Sun-style 24 forms Tai Chi exercise is effective in decreasing pain, stiffness, fear of falling and it improves balance, rising time, and knee joint motion. We suggest a continuing long term intervention to decrease disability and increase efficacy concerning falls.
노랑초파리의 GD STERILITY 에 관한 온도 및 AGE 의 영향에 관한 연구
이혜영,지관자 한국유전학회 1987 Genes & Genomics Vol.9 No.4
An experiment was carried out to investigate the influence of temperature and aging on GD sterility from reciprocal crosses with π_2strain and Canton-S strain of Drosophila melanogaster. It was found that the GD sterility traits were observed display a characteristic reciprocal cross effect by low egg production and strongly depend on female aging effect and sensitive in various temperature. It was concluded that the GD sterility was induced by high and narrow range of temperature 25℃-29℃ and age a female produced high egg production.
이혜영,김정옥,이종미,정진,오은지 대한진단검사의학회 2022 Laboratory Medicine Online Vol.12 No.1
Background: Lymphocyte subset analysis is essential to evaluate the engraftment status in hematopoietic stem cell transplantation (HSCT). Au- tomated gating tools are widely used for flow cytometry analysis. Unlike healthy individuals, different cell populations and aberrant expressions may occur in HSCT samples. In the present study, we evaluated the applicability of automated gating in HSCT recipients by comparing it to expert- based manual gating. Methods: Lymphocyte subset was performed using Beckman Coulter Navios (Beckman Coulter, USA) flow cytometry. Data files from 22 patients with hematologic malignancies were analyzed in parallel by manual gating and automated gating using Navios Tetra software. Quality control re- sults and reproducibility were evaluated using IMMUNO-TROL controls. Results: Spearman rank correlation coefficients between the two gating methods were > 0.970 in all cell populations except CD8+ T cells. CD8+ T cell counts via automated gating were higher than those of manual gating in all cases due to the T cell populations with reduced CD8 ex- pression. Automated gating program failed to identify CD4+CD8+ double-positive T cell population. Moreover, it excluded certain lymphocytes with low forward scatter (FSC) and high side scatter (SSC). Furthermore, two HSCT recipients revealed a high percentage of CD56−CD16+ NK cells, we found the need to add CD16 reagent to the Navios system. All coefficients of variation were < 10% except for CD56+ NK cells via auto- mated gating. Conclusions: Manual gating confirmation via flow cytometry histogram is necessary to identify the aberrant phenotypes and unexpected cell populations in HSCT recipients.