태권도 품새 수련이 아동의 심박수, 심근산소소비량, 에너지 대사에 미치는 영향

정성태,전태원,박익렬,정덕조,우재홍,이광희,이동기,강현주 서울대학교 체육연구소 2000 서울大學校 體育硏究所論集 Vol.21 No.1

The Taegeuk Poomse 1 through 8 of Taekwondo are based upon eight major branches of philosophical theories. The propose of this study was to investigate the nfluence of Taekwondo poomse trainning on heart rate, MVO2, energy metabolism in primary school students. Subjects for this study were eight male the fifth∼sixth grades students who participated in exercise program consist of Taekwondo poomse trainning in dojang which is located in Shinlim-2dong, Kwanak-Gu, Seoul(12.7± 0.5years, 150.8 ±4.6cm, 45.1 ± 9.4kg, 24.9 ± 9trainning length). The results of thet this study are as follows: 1) The average of heart rate was Taegeuk Poomse 1 through 8 of Taekwondo 90.57± 4.gbeats/min in rest and 139.7 ± 17.5beats/min in exercise. The minimum heart rate was 89.0±2.8, peak heart rate was 167.1 ±6.4 in exercise. It was ranged from 42% to 80% 2) of the max heart rate and ranged 42 to 65%HRmax. Taegeuk 1 Jang was differenced with others Jangs significantly(p<0.05), 2) The time of the Taegeuk 1 through 8 Jang of Taekwondo was 5minutes 12seconds. Heart rate was ranged from 90.6 ± 7.85beats/min to 171.8 ±8.Ibeats/min and increased linearly. 3) The average of the MVO2 was 11.1 ±0.78mmHg · bpm-3 in rest and 19.1 ± 1.2mmHg ㆍbpm-3 in exercise. MVO2 was ranged from 10.5mmHg · bpm-3 to 20.3mmHg · bpm-3. There were not difference between Taegeuk Poomses(p<0.05). 4) The energy metabolism was as follows: Mean VO2 Respiratory exchange ratio, energy consumption were 0.51(V02L/min),0.71(RQ),2.32Ckca1/min) in rest respectively. but In exercise Mean VO2 Respiratory exchange ratio, energy consumption were 0.89 ± 0.18( V 02L/min), 0.79±0.08(RQ), 4.26±0.51(kcal/min) respectively . The difference was only between Taegeuk 1 Jang and Taegeuk 3 Jang(p<0.05). This study showed that the Taekwondo Poomse trainning was proper exercise for fitness, body composition and weight control in normal, abnormal(obese) children because the Taekwondo trainning are dynamic and exciting sport.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

[PA-0015] Genome-wide association study and selective sweeps reveal genetic variations associated Chip Processing clones selected over sixty years in global potato breeding programs

Kwang Ryong Jo(Kwang Ryong Jo),Yong Ik Jin(Yong Ik Jin),Gun Ho Jung(Gun Ho Jung),Jang Gyu Choi(Jang Gyu Choi),Gyu Bin Lee(Gyu Bin Lee),Do Hee Kwon(Do Hee Kwon),Young Eun Park(Young Eun Park) 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-

[PA-0016] Analysis of genetic diversity and population structure among cultivated potato clones from Korea and global breeding programs

Do Hee Kwon(Do Hee Kwon),Yong Ik Jin(Yong Ik Jin),Gun Ho Jung(Gun Ho Jung),Jang Gyu Choi(Jang Gyu Choi),Gyu Bin Lee(Gyu Bin Lee),Kwang Ryong Jo(Kwang Ryong Jo),Young Eun Park(Young Eun Park) 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-

The Effect of Recombinant Tissue Plasminogen Activator on the Intracerebral Hematomas in Experimental Cat Models

Jo, Kwang-Wook,Kim, Seong-Rim,You, Seung-Hoon,Kim, Sang-Don,Park, Ik-Seong,Baik, Min-Woo The Korean Neurosurgical Society 2005 Journal of Korean neurosurgical society Vol.37 No.4

Objective: Recent clinical studies have demonstrated that intracisternal administration of recombinant tissue plasminogen activator(rt-PA) can facilitate the normal clearing of blood from the subarachnoid space. Urokinase, a first generation fibrinolytic agent, has been used to liquify such clots with some success. Therefore, recombinant tissue plasminogen activator, a second generation fibrinolytic drug that may be safer and more effective, is studied to evaluate its dosage to lyse clots in vitro and reactivity in the brain parenchyme. Methods: Intracerebral hematomas were created by stereotactically injecting 2ml of clotted autogenous blood into the brain parenchyme of total 28 anesthetized adult cats (weighting 3.8 to 4.1 kg). The control animals (group A) received 1 ml of normal saline injected into the clots and the experimental animals received each 0.1 mg of rt-PA (group B), 0.5mg of rt-PA (group C) and 1 mg of rt-PA (group D) at 6 hours after the clot injection. Results: 1. The amount of remained clots after lysing the hematomas were as follows: $1.80{\pm}0.17ml$ in group A, $1.65{\pm}0.23ml$ in group B, $0.61{\pm}0.37ml$ in group C and $0.52{\pm}0.34$ in group D. The result indicated that hematomas in rt-PA treated groups (C & D) were lysed better than the control group. 2. At least 0.5mg of rt-PA should be required for the lysis of 2ml of hematomas. 3. Light microscopic examination revealed no histological evidence of hemorrhage in tissue sections from each brain. Conclusion: Recombinant tissue plasminogen activator may be safely and effectively employed for the lysis of intracerebral hematomas in animal model.

Clinical Importance of Work-Exacerbated Asthma: Findings From a Prospective Asthma Cohort in a Highly Industrialized City in Korea

Jo Woori,Seo Kwang Won,Jung Hwa Sik,Park Chui Yong,Kang Byung Ju,Kang Hyeon Hui,Ra Seung Won,Jegal Yangjin,Ahn Jong Joon,Park Soon Eun,Jung Moon Sik,Park Ju Ik,Park Eun Ji,Sim Chang Sun,Kim Tae-Bum,Le 대한천식알레르기학회 2021 Allergy, Asthma & Immunology Research Vol.13 No.2

Purpose: Work-related asthma (WRA) occupies about 10%–30% of all asthma cases. Among 2 subtypes of WRA (occupational asthma [OA] and work-exacerbated asthma [WEA]), the rate of WEA has been reported to increase recently. WRA is described as having worse characteristics than non-WRA (NWRA), while WEA is known to show similar severity to OA in terms of symptoms and exacerbations. However, these data were mainly based on indirect surveys. Ulsan is a highly industrialized city in Korea; therefore, it is estimated to have a high incidence of WRA. This study aimed to identify the characteristics of WRA in the city. Methods: This was a prospective asthma cohort study of individuals diagnosed with asthma and treated at Ulsan University Hospital between Jan 2015 and Dec 2016. Baseline characteristics and work-related inquiry (9 questionnaires) were investigated at enrollment. Various severity indices and job change were then investigated for the longitudinal analysis at 12 months after enrollment. Results: In total, 217 asthma patients completed the study. WRA accounted for 17% (36/217), with an equal number of WEA and OA (18 patients each). Before the work-related survey, only 33% (n = 12) of WRA patients (22% [4/18] of WEA and 44% [8/18] of OA) were diagnosed with WRA by the attending physicians. Compared to the NWRA group and the OA subgroup, the WEA subgroup had more outpatient visits, more oral corticosteroids prescriptions, and trends of low asthma control test scores and severe asthma. The rate of job change was markedly lower in the WEA subgroup than in the OA subgroup (20% vs. 5%). Conclusions: The overall prevalence of WRA (17%) was similar to those of previous studies, but the share of WEA was high (50% of WRA). WEA was more severe than OA or NWRA. The possible reason for this severity is ongoing workplace exposure.

Multiple Applications of Lime Sulfur for Fruit Thinning of ‘Fuji’ and ‘Hongro’ Apple Trees

Ik-Jo Chun(전익조),Wei-Wei Zheng(정위위),Cheol Choi(최철),Yang-Yik Song(송양익),In-kye Kwang(강인규),Peter Hirst(피터 허스트) (사)한국생물환경조절학회 2012 시설원예‧식물공장 Vol.21 No.4

본 연구는 2년간 ‘홍로’/M.9 및 ‘후지’/M.9 품종의 적과를 위한 석회유황합제 및 어유와의 혼합처리 효과를 조사하기 위해 진행하였다. ‘후지’ 1년 차에 있어, 만개 시 석회유황합제 1% 또는 2% 처리는 대조구에 비해 정과 및 액과의 유과수를 감소시켰다. 하지만 2차년도에는 석회유황합제 1% 또는 2% 단용처리에서는 정과 유과수의 차이를 나타내지 않았다. 다만 석회유황합제 1%의 3회 처리에서는 1차년도와 2차년도 모두 유의적인 적과효과를 나타내었다. 석회유황합제 1%의 다중처리는 ‘홍로’에서 가장 효율적인 적과효과를 나타내었다. 1차년도의 경우, 석회유황합제 1%의 2회 또는 3회 살포가 효과적인 적과효과를 보였으며, 2차년도에서는 석회유황합제 1% 1회처리를 제외하고는 모두 유의적인 적과효과를 나타내었다. 첨가된 어유의 경우 대부분의 경우 석회유황합제의 적과효과를 강화하지 않았다. 본 시험에 사용된 모든 처리구는 과실의 동녹 형성에 악영향을 미치지 않았으며, 또한 ‘후지’ 및 ‘홍로’의 과실 중량, 경도, 가용성고형물 및 적정산도와 같은 과실품질에 영향을 미치지 않았다. The thinning effects of lime sulfur either alone or combined with fish oil on two apple cultivars ‘Fuji’/M.9 and ‘Hongro’/M.9 were investigated during two consecutive seasons. Either 1% or 2% lime sulfur at full bloom decreased the amounts of both terminal and axillary fruits compared with unsprayed ‘Fuji’ control trees in the first year. However, 1% or 2% lime sulfur did not decrease terminal fruit set in the second year. Only, triple applications of 1% lime sulfur significantly reduced the number of terminal and axillary fruits in both years. Multiple application of 1% lime sulfur was the most effective in thinning of ‘Hongro’. In the first year, double or triple applications of 1% lime sulfur was effective in thinning terminal or axillary fruit, but one time applications of 1% or 2% lime sulfur was not reduced axillary fruit in ‘Hongro’ apple trees. In the second season, all treatments reduced terminal or axillary fruit in ‘Hongro’ clusters, except single application of 1% lime sulfur. Fish oil did not always improve the thinning effects of lime sulfur in ‘Fuji’ or ‘Hongro’ apple trees. None of treatments caused significant russeting in the harvested fruits. Most of thinning treatments had little effect on ‘Fuji’ or ‘Hongro’ fruit quality in terms of fruit weight, firmness, soluble solids concentration or titratable acidity.

뇌하수체 졸증 후에 자발적으로 소멸된 뇌하수체 종양 -증례보고-

조광욱 ( Kwang Wook Jo ),박성만 ( Sung Man Park ),박익성 ( Ik Seong Park ) 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 2009 대한뇌종양학회지 Vol.8 No.2

Pituitary apoplexy refers to a clinical syndrome caused by the sudden expansion of a pituitary tumor that compresses nearby structures. In spite of much debate, if there is a neurolo-ophthalmic problem, emergent surgical decompression has been known as the ideal treatment. However, we experienced a rare case in which a pituitary tumor showed spontaneous regression after apoplexy. The tumor was only given conservative care. Thus, the authors will report on the case with a brief literature review.

계절에 따른 골판지 원지의 강도변화에 대한 연구 (1)

이광섭(Kwang Seob Lee),박열림(Yell Rim Pak),오준(Jun O),조상우(Woo Sang Jo),조정익(Ik Jeong Jo),류정용(Jeong Yong Ryu) 한국펄프·종이공학회 2016 펄프.종이기술 Vol.48 No.3

Linerboards have been produced by recycling recovered paper such as old corrugated containers(OCC). Usually linerboards produced during summer season show weak strength compared with those of produced during winter. In order to cope with the weak strength of linerboards produced during summer, and to confirm uniform quality, it is important to understand the seasonal effect on strength properties. Effect of pulping temperature of the OCC for linearboard production was investigated by controlling pulping temperatures at 18℃ and 51℃. Low pulping temperature (18℃) caused more generation of fines in stock. Consequently retention and drainage of linerboard defibrated at high pulping temperature (51℃) were better than those of 18℃. Strength properties of handsheet at low pulping temperature were higher than those of high pulping temperature and it could be confirmed that low pulping temperature during winter is one reason of seasonal variation of recycled linerboard strength. It is considered that surface modification of OCC fibers by harsh pulping action during winter caused increase of paper strength.

생활하수 및 산업폐수 슬러지 처리에 따른 콩의 중금속 및 아미노산 함량

문광현(Kwang-Hyun Moon),김재영(Jae-Young Kim),장문익(Moon-Ik Chang),김운성(Un-Sung Kim),김성조(Seong-Jo Kim),백승화(Seung-Hwa Ba다) 한국식품영양과학회 2013 한국식품영양과학회지 Vol.42 No.2

본 연구는 생활하수 및 산업폐수 슬러지를 연차적으로 경작지에 처리한 후, 재배된 콩 식물체의 중금속 흡수 정도와 영양성분에 미치는 영향을 조사하였다. 처리량은 무처리, 11.25, 22.50 및 45.00 Mg/ha로 하였으며, 재배된 콩 식물체의 부위별 Cd, Pb, Ni, Cu 및 Zn 함량과 콩 종실의 수확량, 단백질 및 아미노산 함량을 조사하였다. 콩 종실 중의 Cd 함량은 0.02~0.05 mg/kg으로 기준치에 안전한 수준이었고, Pb 함량은 산업폐수 슬러지 45 Mg/ha를 제외하고 0.02~0.15 mg/kg으로 기준치에 적합하였다. 또한, 모든 중금속축적률은 잎 또는 뿌리보다 식용부위인 콩 종실에서 상대적으로 낮았고, 슬러지 처리량의 증가에도 함량 변화는 적어 식용으로서 안전함을 확인하였다. 종실의 수확량은 1년차에 슬러지 처리군이 무처리군보다 높았지만 2년차에는 생활하수 슬러지의 경우 낮은 수확량을 보였고, 산업폐수 슬러지의 경우 유사한 수준 또는 감소하는 경향이었다. 생활하수 슬러지 처리에 따른 아미노산 함량은 glutamate 경우에만 슬러지 처리군이 무처리군보다 증가하는 경향이었다. 하지만 연용에 따른 변화는 12종에서만 무처리군보다 증가하고 있었다. 산업폐수 슬러지는 1년차의 경우 15종이 무처리군에서 가장 높았고, 2년차에서는 11.25 Mg/ha에서 17종 모두가 가장 높은 결과를 나타내었다. 결론적으로 콩 종실 중 중금속 축적량은 문제가 되지 않았으나 수량이 감소되는 점을 감안할 때 가장 적합한 슬러지 처리 수준은 11.25 Mg/ha임을 확인하였다. This study investigates the effects of accumulated levels of heavy metals and nutrients of cultivated soybean plant tissues, after the continuous application of sewage sludge (SS) and industrial sludge (IS). SS and IS were applied to soybean plants at loading of 0, 11.25, 22.50, and 45.00 Mg/ha, and the contents of heavy metals (Cd, Pb, Ni, Cu, and Zn), proteins, and amino acids in the cultivated soybean plants were measured. The Cd content in the soybean was 0.02~0.05 mg/kg, which is within the safety level set in the standard, and that of Pb was 0.02~0.15 mg/kg, which is also within the safety level except for IS 45 Mg/ha. The soybean harvest quantity was higher in the treatment groups than the control group in the first year. However, in the second year, SS had lower harvest and IS had the same level or a decreasing tendency, compared with the control group. In the first year, the content of amino acid which followed handling of SS was increased in the sludge groups more than in the control group in the case of glutamate. However, the influence of continuous application was increased in the sludge groups in the case of amino acids of 12 types. In conclusions, the accumulation in soybean of heavy metals by sludge treatment is not a problem, but the decreased yields needs to be considered. In addition, the most appropriate level of sludge treatment was 11.25 Mg/ha.