Proteomic Approach to Analyzing Flooding Stress in Soybean (Glycine max(L.) Merr.)

Kim,Tae-Seon,Cho,Seong-Woo,Lee,Jae-Eun,Kim,Yook-Han,Cho,Kun,Choi,Jong-Soon,Chung,Keun-Yook,Song,Beom-Heon,Jong,Seung-Keun,Kim,Hong-Sig,Woo,Sun-Hee 한국작물학회 2005 한국작물학회 학술발표대회 논문집 Vol.2005 No.-

생체분해성 망막압정을 이용한 망막고정에 대한 실험적 연구

김용백,민병무,김창식,박근성,김승영,길숙종,조항진,이성복,노승무,송규상,강대영,조준식,양준묵,정경수,최선웅,이진호,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Biodegradable retinal fixation devices obtain mechnical fixation of the retina with desirable chorioretinal scarring and with the potential for local, sustained release of antimetabolites and steroids to inhibit proliferative vitreoretinopathy. We manufactured a biodegradable retinal tack with barb that was designed in order to prevent intrusion from implantation of retinal tacks. This study was carried to evaluate the efficacy for retinal fixation and the capability for sustained release of drugs with a newly designed biodegradable retinal tack Biodegradable retinal tacks were made of polymers of glycolic acids and were designed with barbs in a shape to prevent the disinsertion. Biodegradale retinal tacks are divided into 3 parts, a conical portion that is inserted into the sclera, a cylinder portion that remains in the vitreous, and a neck portion between the pin and the cylinder. The tapered conical end was manufactured to allow easy insertion through the retina and choroid into the sclera. A cylinder portion was manufactured with a tapered angle that fixes firmly into the orifice of 19 gauge spinal needle. A neck portion, 0.4 mm in diameter, was designed to prevent disinsertion from following implantation of retinal tack. The applicator was a 19 gauge spinal needle and its orifice was prepared to 15°angle to accept the tapered cylinder portion of the retinal tack. The retinal tacks, secured in the needles, were passed through the formed vitreous and inserted into the retina, choroid, and sclera and were released by pushing the internal needle, usually within 2-3mm of the medullary ray of the posterior rabbit retina A retinal tack was placed in each of 8 pigmented rabbit eyes. Slit-lamp biomicroscopy, indirect ophthalmoscopy and fundus photography were performed periodically from 1 day to 8 weeks after surgery. Eight eyes were enucleated and studied by light microscopy at 8 weeks. Biomicroscopic evaluation of the animals revealed edemas adjacent to the retinal surfaces immediately after insertion of the biodegradable retinal tacks in all the animals. These edemas disappeared after 1 week. The first noticeable change in the size of retinal tacks was shown after 2weeks. The size of the retinal tacks gradually got smaller, decreasing to about one-half at 4 weeks and about one-third at 8 weeks. All retinal tacks remained in inserted places without any movement for an 8 week period. On light microscopy, epiretinal proliferations were seen to extend into the vitreous cavity. Cellular capsules that lined the inner aspect of the scleral defect caused by tack insertion were found. However the adjacent retina had a normal cytologic appearance and architecture in all specimens. We manufactured a biodegradable retinal tack that is designed to prevent intrusion from implantation of retinal tacks. All biodegradable retinal tacks reduce in size with time, but no retinal tacks extruded from the inserted place. The newly designed biodegradable retinal tack can be used for retinal fixation and may be used as a vehicle for the introduction of pharmacologic agents to prevent the cellular events that promote proliferative vitreoretinopathy.

8년간(1992~1999) 산업안전보건연구원에 의뢰된 직업병 심의 사례 분석

강성규,김규상,김양호,최정근,안연순,진영우,최병순,양정선,김은아,채창호,최용휴,김대성,박정선,정호근 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : Pneumoconisis and noise-induced hearing loss (NIHL) have been reported as main occupational diseases by the Special Health Examination. The Industrial Accident Compensation Insurance has reported various work-related diseases, however, these two diseases occupied almost a half of compensated cases. Therefore, it was not well known about the status of occupational diseases other than pneumoconiosis, NIHL, and cardio-cerebrovascular accident (CVA). This study was conducted to analyze claimed cases as an occupational disease, that was requested to the Korea Industrial Safety and Health Agency (KOSHA). Methods : The local office of the Korea Labor Welfare Corporation (KLWC) has asked the KOSHA for confirmation of claimed cases as an occupational disease. We analyzed 379 cases requested from KLWC, the Ministry of Labor, employers, unions and occupational health agencies from 1992 to 1999. Results : Male was 80.7 % of the requested cases. Their mean age was 42 years old and 75.5 % of them were more than 35 years old. The requested cases were increased rapidly from 25 cases in 1992 to 108 cases in 1999 and the accept rate was 50.7 %. The majority of requested cases were respiratory diseases(22.4%), cancers(18.5%), Neuropsychiatric problems(14.5%), and musculoskeletal problems(13.5%). The accept rate was high in reproductive, respiratory, musculoskeletal and digestive disorders and low in neuropsychiatric, renal and otologic problems and occupational cancers. 73.6% of them were caused by chemical agents, especially 28.5 % were by organic solvents. 67% of them were clinically confirmed at university hospitals. A half of the cases were from KyongIn area, even the request came from the whole country. Conclusions : A claim was common in workers whose age was over 35 years old and exposure history was over 10 years. The respiratory diseases and neuropsychiatric disorders were still main problems in occupational health and occupational cancers was increasing even though its accept rate was not high yet.

생체분해성 고분자를 이용한 사시수술용 제형개발 및 효용성에 대한 연구

민병무,김용백,김승영,김창식,박근성,길숙종,조항진,이성복,노승무,송규상,강대영,조준식,양준묵,정경수,최선웅,이진호,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

A new device, muscle clamping system was developed to facilitate exact quatifying technique A strabismus surgery, and reduce the risk of complications. The device is composed of a lower fixing body with three jaws and an upper supporting body. They are used to clip an extraocular muscle and fix it to the sclera with a single bite. Superior rectus recession on 16 rabbit eyes were performed with this new device. Conjunctival injection, muscle adhesion strength, and light microscopic findings were examined at 1, 2, 4 and 8 weeks postoperatively. The Conjunctival injection were minimal, adhesion power ranged from 420 to 600 gram gravity, which is sufficient in withstand the normal pull of human extraocular muscle. In microscopic exam, some Inflammatory cells and fibrosis were found. The new device was technically easy, fast, and accurate, so it may be useful in stabismus surgery.

다중 경로 채널에서의 ATC를 적용한 DMF 초기동기 장치의 성능분석

김성철,송인근 우송대학교 1998 우송대학교 논문집 Vol.3 No.-

To analyze the DS/SS reciever performance with respect to coed acquisition, multipath fading channel is characterized as a two-ray Rayleigh fading channel. In the code acquisition loop, the performance is evaluated in terms of the acquisition time and detection probability with the acquisition time is taken into account. To improve the performance, ATC (automatic gain control) algorithm is proposed. The simulation results show that high sampling rate improves the performance and in case of high SNR, the performance of the DMF acquisition system has a little difference between AWGN and Rayleigh fading channel.

VITAMIN E劑가 全身持久力 向上에 미치는 影響

金敎成,曺根鍾 漢陽大學校 體育科學硏究所 1986 體育科學 Vol.6 No.6

The purpose of this study was to investigate effect of Vitamin E on improvement of cardiovascular endurance. Selected subiects-12 soccer players and 12 general high school boys were divided into 4 groups as follows. A; Soccer players who were trained after taking Vitamin E, (6 persons) B; Soccer players who were trained only, not dosage. (6 persons) C: General students who were trained after dosed Vitamin E, (6 persons) D; General students who were not trained, but taking Vitamin E. (6 persons) Each group was trained for 5 weeks by training program. (17 mins/day, 3 days/ week), after training measured and analysised heart-rate, vital-capacity, 1000m race-record, heart-rate after 1000m race in every 5 weeks. The conclusions are as follows: 1. Resting heart-rate lowed 4. 0 beats/min in A, C group (P<0.05) after training but control group was not lowed. 2. Vital-capacity increased in C group(287cc, P<0.001) and A group (149cc, P<0.05). 3. 1000m race record improved in order of C-A-B group so, each group was shortened 17 sec (P<0.05) , 12 sec (P<0.05) 11 sec (P<0.05) 4. Heart-rate after 1000m race improved in order of C-A-K group so, each group was lowed 6.6 beats/min, 6.0 beats/min, 5.6 beats/min(P<0.05). Synthetically cardiovascular endurance improved both players and general group but general group rather than players. The result indicated that Vitamin E was effected to improvement of cardiovascular endurance. But there was no improvement of cardiovascular endurance in K group except 1000m race record. It was that the result was not dosage effect but training effect.

알콜의 연속투여가 수면구조와 일부 정동에 미치는 영향

김세인,신석철,왕성근 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

To investigate the effects of short-term administration of alcohol on the sleep patterns and subjective physiological function(some aspects of emotion), the author applied polysomnography, reaction time and visual analogue test to the volunteer male students. The subjects were 8 healthy young adults, ranging in age from 21 to 26 years, without personal past nor present histories of singificant medical, neurological, or psychiatric illness and suffering from no current major sleep disturbances or parasomnias. After one night sleep of adaptation, each subject was ingested alcohol(43% whisky 3ml/kg) for 5 successive nights and was withdrawn for 3 days, and polysomnography was recorded in the sleep laboratory. Also, reaction time was performed and visual anlogue test were applied to measure the degree of fatigability, mood, and sleepiness for 5 times a day(at 9 : 00, at noon, at 15 : 00, at 18: 00 and at 21 : 00). The results were summarized as follows. 1. Compared with the baseline, sleep latency was significantly shortened during the period of alcohol drinking, and the absolute value(minutes) of stage 3, 4 sleep and SWS, and the relative value(%) of stage 4 sleep were increased significantly in the third drinking night. 2. REM latency was significantly increased in the third and fifth drinking night, and there were no significant change in REM number, REM cycle, and REM duration. 3. There was a significant positive correlation between all the period of drinking and withdrawal nights and the baseline on WASO(waking time after sleep onset), and a significant positive correlation between the 1st, 3rd and 5th drinking night and the baseline on the absolute value(minutes) of SWS and a significant positive correlation between the 3rd and 5th DN and the baseline on the relative value(%) of SWS. 4. Compared with the baseline, feeling of fatigue was significantly severe in the 3rd and 5th drinking day and in the 1st withdrawal day, and there was no difference in the 3rd withdrawal day. 5. Compared with the baseline, mood was significantly worse in the 3rd and 5th drinking day and in the 1st withdrawal day, and there was no difference in the 3rd withdrawal day. 6. Compared with the baseline, sleepiness was significantly increased in the 3rd and 5th drinking day and in the 1st withdrawal day, and there was no diffenence in the 3rd withdrawal day.

진단방사선영역에서 Ho 여과판 사용시 피폭선량 감소와 화질개선에 관한 연구

김영근,이성길 광주보건대학 2000 論文集 Vol.25 No.-

This work was reduction of exposure dose and improvement of image quality by use of Ho filter in diagnostic fadiology, From the results of experimental evaluation, it was founded that in the case of the Ho filter, the variety of X-ray property with kVp was less than those of Cu and Al. And the ratio of transit to surface-dose and the load of X-ray tube were increased in the order Al, Cu, Gd and Ho. The contrast of X-ray image showed the higher value in the order of Cu, Al, Gd and Ho.

정상 성인에서 수면박탈이 수면구조와 피로감에 미치는 영향

김완중,신석철,왕성근 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

To identify the effects of sleep deprivation on sleep structure polysomnography was performed for 10healthy young adults. Visual analogue scale was also used to identify the effects of sleep deprivation on fatigue, mood, and sleepiness. The subjects were young adults, ranging in age from 21 to 26 years, without past or present histories of significant medical, neurological, or psychiatric illness as well as no current major sleep disturbances or parasomnias. After one adaptation night, each subject was recorded polysomnography in the sleep laboratory. Sleep records were analyzed according to the criteria of Rechtschaffen and Kales every 20 seconds, and tried paired-t-test and correlation. The results were summarized as follows. 1. After one night of total sleep deprivation, compared with the baseline, TST, stage 3, stage 4, and SWS were significanlty increased, and sleep latency was significantly shortened, and return to normal level after 3 nights of recovery. 2. The relative value(%) of stage 3, stage 4, and SWS were positive correlation between the baseline and the first recovery night. 3. Compared with the baseline, reaction time was significantly delayed in the first recovery night, and returned to normal level after 3 days of recovery. 4. The feeling of fatigue, mood, and sleepiness were significantly worsened in the first day after TSD, and returned to normal level after 3 days of recovery.

승모판 대치술후에 발생한 좌심실유출로 폐색 1예

김도연,조홍근,정익모,박시훈,박성훈,신길자,정병철 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.1