급성 호흡부전의 치료: 비침습적 기계환기

박성훈 대한의사협회 2022 대한의사협회지 Vol.65 No.3

Background: Noninvasive ventilation (NIV) has been an important strategy to support patients with respiratory failure, while preventing complications assorted with invasive mechanical ventilation. Physicians need to be aware of the various roles of NIV and the challenges encountered in clinical practice. Current Concepts: Traditionally, the application of NIV has been well-known to be associated with reduced mortality in patients with chronic obstructive pulmonary disease (COPD) or acute pulmonary edema and those suffering from acute respiratory failure. However, despite some positive results of NIV treatment in patients with de novo hypoxemic respiratory failure such as acute pneumonia or acute respiratory distress syndrome, NIV failure (or delayed intubation) can have deleterious effects on patients outcomes. Besides, the aggravation of lung injury should also be taken into consideration when applied to patients exhibiting high respiratory drive. Nonetheless, NIV has potential for wide applications in various clinical situations such as facilitation of ventilator weaning, post-operative respiratory failure, or palliative treatment. Discussion and Conclusion: In addition to the strong evidence in patients with acute respiratory failure due to COPD or acute pulmonary edema, the NIV treatment can be potentially used for various clinical conditions. However, compared to European countries, the prevalence of NIV use continues to remain lower in South Korea. Nevertheless, when applied in appropriately selected patients in a timely manner, NIV treatment can be associated with improved patient outcomes.

Is Robot-Assisted Surgery Really Scarless Surgery? Immediate Reconstruction with a Jejunal Free Flap for Esophageal Rupture after Robot-Assisted Thyroidectomy

박성훈,김주현,이준원,정희선,이동진,김병천,서인석 대한성형외과학회 2017 Archives of Plastic Surgery Vol.44 No.6

Esophageal perforation is a rare but potentially fatal complication of robot-assisted thyroidectomy (RAT). Herein, we report the long-term outcome of an esophageal reconstruction with a jejunal free flap for esophageal rupture after RAT. A 33-year-old woman developed subcutaneous emphysema and hoarseness on postoperative day1 following RAT. Esophageal rupture was diagnosed by computed tomography and endoscopy, and immediate surgical exploration confirmed esophageal rupture, as well as recurrent laryngeal nerve injury. We performed a jejunal free flap repair of the 8-cm defect in the esophagus. End-to-side microvascular anastomoses were created between the right external carotid artery and the jejunal branches of the superior mesenteric artery, and end-to-end anastomosis was performed between the external jugular vein and the jejunal vein. The right recurrent laryngeal nerve injury was repaired with a 4-cm nerve graft from the right ansa cervicalis. Esophagography at 1 year after surgery confirmed that there were no leaks or structures, endoscopy at 1 year confirmed the resolution of vocal cord paralysis, and there were no residual problems with swallowing or speech at a 5-year follow-up examination. RAT requires experienced surgeons with a thorough knowledge of anatomy, as well as adequate resources to quickly and competently address potentially severe complications such as esophageal rupture.

경식도심초음파가이드를 이용한 승모판풍선성형술

박성훈,김명아,현민수 대한순환기학회 1997 Korean Circulation Journal Vol.27 No.7

일반연제발표 : 구연 ; 중환자실 혈액종양 환자의 예후 예측에 있어 SAPS 2 와 SOFA Score의 비교

박성훈,서지영,권용수,김명훈,김이형,윤종욱,박혜윤,고원중,정만표,김호중,권오정 대한결핵 및 호흡기학회 2006 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.103 No.0

Antiobesity Effect of Recombinant Human Caseinomacropeptide in Sprague-Dawley Rat

박성훈,강환구,박건영,Yu-Jin Kim,오유관,Seung-Shick Yoo 한국생물공학회 2005 Biotechnology and Bioprocess Engineering Vol.10 No.3

Caseinomacropeptide (CMP) is a glycopeptide of 64 amino acid residues derived from the C-terminal of mammalian milk -casein. Recently, human CMP (hCMP) was produced from the recombinant yeast Saccharomyces cerevisiae. In this study, the antiobesity activity of the recombinant hCMP (rhCMP) was investigated in vivo using Sprague-Dawley rats. The rhCMP did not affect the rats fed with a normal fat diet (fat content, 5.0%), but decreased the body weight gain of the rats fed with a high fat diet (fat content, 20%) by up to 19%. Autopsies revealed that the weights of the liver, kidney and adipose tissues decreased when the rats were given the rhCMP, which also reduced the lipid concentrations in the plasma and liver, but enhanced the fecal excretion of lipids. These results suggest that rhCMP prevent the accumulation of lipid by stimulating its fecal excretion, so could be used as a food supplement to alleviate the obesity problem caused by a high fat diet.

How Selfish Contestants Use Endogenous Emotions to Increase Subjective Utilities

박성훈,Jason Shogren 한국국제경제학회 2020 International Economic Journal Vol.34 No.1

We study a two-player contest in which each egoistic player can choose to release his emotion information to the rival. Each player selects his emotion-parameter value to maximize his material payoffs and his effort level to maximize his subjective utility. There are different equilibria depending on the difference between the abilities of the players. The favorite reveals his envious emotion and the underdog his altruistic emotion in the equilibrium if the favorite’s ability is moderately higher than that of the underdog. Our results suggest that the classic result of the favorite-as-follower does not occur in the equilibrium of the full game.

RBL 2H3 비만세포에서 히스타민 유리와 칼슘과의 관계

박성훈,김수정,김정민,박주현,최방실,이지윤,최미영,심상수,Park, Sung-Hun,Kim, Soo-Jeong,Kim, Jung-Min,Park, Ju-Hyun,Choi, Bang-Shil,Lee, Ji-Yun,Choi, Mi-Yeong,Sim, Sang-Soo 대한약학회 2007 약학회지 Vol.51 No.1

To investigate the relation between extracellular Ca$^{2+}$ and histamine release, we observed agonist-induced histamine release from RBL 2H3 mast cells in the presence or absence of extracellular Ca$^{2+}$ concentration. Histamine release induced by melittin and thapsigargin were greater in the presence of extracellular Ca$^{2+}$ than in the absence of extracellular Ca$^{2+}$. Econazole-induced histamine release had nothing to do with extracellular Ca$^{2+}$, whereas arachidonic acid-induced histamine release increased in the absence of extracellular Ca$^{2+}$. Calmodulin antagonists did not affect melittin-induced histamine release but they may potentiate arachidonic acid-induced histamine release. These data suggest that arachidonic acid-induced histamine release may be mediated via Ca$^{2+}$-independent pathway and may be potentiated by the block of Ca$^{2+}$-dependent pathway.

Color Removal of Real Textile Wastewater by Sequential Anaerobic and Aerobic Reactors

박성훈,송승구,오유관,Yu-Jin Kim,Yeonghee Ahn 한국생물공학회 2004 Biotechnology and Bioprocess Engineering Vol.9 No.5

Textile wastewater from the Pusan Dyeing Industrial Complex (PDIC) was treated utilizing a two-stage continuous system, composed of an upflow anaerobic sludge blanket reactor and an activated sludge reactor. The effects of color and organic loading rates were studied by varying the hydraulic retention time and influent glucose concentration. The maximum color load to satisfy the legal discharge limit of color intensity in Korea (400 ADMI, unit of the American Dye Manufacturers Institute) was estimated to be 2,700 ADMIL-1 day-1. This study indicates that the two-stage anaerobic/aerobic reaction system is potentially useful in the treatment of textile wastewater.

Tailoring environment friendly carbon nanostructures by surfactant mediated interfacial engineering

박성훈,배준원 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.30 No.-

Since the discoveries of fullerene and carbon nanotube, carbon nanostructures have become one of themost exciting and expanding research topics. Owing to the extraordinary physical, chemical, electrical,and mechanical properties, carbon nanostructures have been considered as promising candidatematerials for diverse energy storage/conversion systems, sensors, biological media, and electronicdevices. Herein, the typical fabrication procedures for carbon nanostructures using interfacialengineering such as emulsion, dispersion, and vapor deposition are summarized. On the other hand,the characteristics and performances of those carbon nanomaterials as major components for numerousdevices are briefly described. In addition, the impressive recent progresses will also be highlightedconcisely.

이옥(李鈺)의 「전」 에 나타난 풍자연구 : 주제와 대상을 중심으로

박성훈 근역한문학회 1984 한문학논집(漢文學論集) Vol.2 No.-