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      • KCI등재

        RBL 2H3 비만세포에서 히스타민 유리와 칼슘과의 관계

        박성훈,김수정,김정민,박주현,최방실,이지윤,최미영,심상수,Park, Sung-Hun,Kim, Soo-Jeong,Kim, Jung-Min,Park, Ju-Hyun,Choi, Bang-Shil,Lee, Ji-Yun,Choi, Mi-Yeong,Sim, Sang-Soo 대한약학회 2007 약학회지 Vol.51 No.1

        To investigate the relation between extracellular Ca$^{2+}$ and histamine release, we observed agonist-induced histamine release from RBL 2H3 mast cells in the presence or absence of extracellular Ca$^{2+}$ concentration. Histamine release induced by melittin and thapsigargin were greater in the presence of extracellular Ca$^{2+}$ than in the absence of extracellular Ca$^{2+}$. Econazole-induced histamine release had nothing to do with extracellular Ca$^{2+}$, whereas arachidonic acid-induced histamine release increased in the absence of extracellular Ca$^{2+}$. Calmodulin antagonists did not affect melittin-induced histamine release but they may potentiate arachidonic acid-induced histamine release. These data suggest that arachidonic acid-induced histamine release may be mediated via Ca$^{2+}$-independent pathway and may be potentiated by the block of Ca$^{2+}$-dependent pathway.

      • KCI등재
      • KCI등재

        인터넷 쇼핑몰 니즈 분석 시스템의 설계 및 구현

        박성훈,김진덕,Park, Sung-hoon,Kim, Jindeog 한국정보통신학회 2015 한국정보통신학회논문지 Vol.19 No.9

        온라인에서 제품을 고르고 실질적인 구매는 오프라인에서 이루어지는 역 쇼루밍이 급격히 늘고 있다. 역 쇼루밍이 늘고 있다는 것은 이미지와 설명을 기반으로 한 인터넷 쇼핑몰의 사용자 분석에 한계가 있음을 의미한다. 따라서 대형 온라인 쇼핑몰은 고객 맞춤형 쇼핑정보를 제공하고 있으나, 단순히 고객이 검색하거나 구매한 상품을 나열하여 제공하여 준다. 따라서 사용자의 다양한 요구를 분석하고 적용할 수 있는 온라인 쇼핑몰이 필요하다. 본 논문에서는 새로운 니즈분석 시스템을 제안한다. 제안된 시스템은 사용자 정의 모듈과 후기 분석 모듈로 구성되어 있다. 전자는 두 개의 상품을 지정하고 개인별 사용자 선호도를 수집하며, 후자는 저장된 데이터베이스 사전을 이용하여 구매 상품의 후기를 분석한다. 구현된 시스템은 개별 사용자의 요구를 충족하는 상품을 추천할 수 있음을 보였다. Even though users choose goods they want to buy in on-line shopping malls, real purchase is often performed in off-line shopping malls. It is called reverse showrooming. It means that users' analysis of goods based on images and description of internet shopping malls has limitation. Thus, large-scale online shopping malls provide a customized shopping information. However, in that case, the provided information is a simple list of goods users bought or retrieved. Thus, a system to analyze various needs of users and apply the result into on-line shopping mall is necessary. In this paper, an analysis system is proposed. The system contains a module to analyze user defined preference and a module to analyze users' reviews. The former designates two goods and collects preferences of individual users. the latter analyzes reviews about purchased goods based on database dictionary stored in advance for analyzing reviews. The system implemented shows that it is possible to recommend some goods that meet each users's needs

      • KCI등재
      • KCI등재

        Radiofrequency Ablation Treatment for Renal Cell Carcinoma: Early Clinical Experience

        박성훈,윤성국,조진한,오종영,남경진,권희진,김수연,강명진,최순섭,성경택 대한영상의학회 2008 Korean Journal of Radiology Vol.9 No.4

        Objective: To evaluate the early clinical experience associated with radiofrequency (RF) ablation in patients with renal cell carcinoma (RCC). Materials and Methods: The RF ablation treatment was performed on 17 tumors from 16 patients (mean age, 60.5 years; range, 43 73 years) with RCC. The treatment indications were localized, solid renal mass, comorbidities, high operation risk, and refusal to perform surgery. All tumors were treated by a percutaneous CT (n = 10), followed by an US-guided (n = 2), laparoscopy-assisted US (n = 2), and an open (n = 2) RF ablation. Furthermore, patients underwent a follow-up CT at one day, one week, one month, three and six months, and then every six months from the onset of treatment. We evaluated the technical success, technical effectiveness, ablation zone, benign periablation enhancement, irregular peripheral enhancement, and complications. Results: All 17 exophytic tumors (mean size, 2.2 cm; range, 1.1 5.0 cm) were completely ablated. Technical success and effectiveness was achieved in all cases and the mean follow-up period was 23.8 months (range, 17 33 months). local recurrence was not detected in any of the cases; however, five patients developed complications as a result of treatment, including hematuria (n = 2), mild thermal injury of the psoas muscle (n = 1), mild hydronephrosis (n = 1), and fistula formation (n = 1). Conclusion: The RF ablation is an alternative treatment for exophytic RCCs and represents a promising treatment for some patients with small RCCs. Objective: To evaluate the early clinical experience associated with radiofrequency (RF) ablation in patients with renal cell carcinoma (RCC). Materials and Methods: The RF ablation treatment was performed on 17 tumors from 16 patients (mean age, 60.5 years; range, 43 73 years) with RCC. The treatment indications were localized, solid renal mass, comorbidities, high operation risk, and refusal to perform surgery. All tumors were treated by a percutaneous CT (n = 10), followed by an US-guided (n = 2), laparoscopy-assisted US (n = 2), and an open (n = 2) RF ablation. Furthermore, patients underwent a follow-up CT at one day, one week, one month, three and six months, and then every six months from the onset of treatment. We evaluated the technical success, technical effectiveness, ablation zone, benign periablation enhancement, irregular peripheral enhancement, and complications. Results: All 17 exophytic tumors (mean size, 2.2 cm; range, 1.1 5.0 cm) were completely ablated. Technical success and effectiveness was achieved in all cases and the mean follow-up period was 23.8 months (range, 17 33 months). local recurrence was not detected in any of the cases; however, five patients developed complications as a result of treatment, including hematuria (n = 2), mild thermal injury of the psoas muscle (n = 1), mild hydronephrosis (n = 1), and fistula formation (n = 1). Conclusion: The RF ablation is an alternative treatment for exophytic RCCs and represents a promising treatment for some patients with small RCCs.

      • KCI등재

        선호도 분석을 위한 내·외부 SNS 활용기법

        박성훈,김진덕,Park, Sung-Hoon,Kim, Jindeog 한국정보통신학회 2015 한국정보통신학회논문지 Vol.19 No.12

        SNS(Social Network Service)의 등장으로 쇼핑 패턴이 변화하고 있다. 최근의 쇼핑몰은 고객의 니즈를 반영한 상품정보 제공에 관심을 갖고 있다. 일반적으로 제공되는 정보는 사용자의 단순 검색 이력을 기반으로 한 상품정보를 제공하는 수준이며, 추천되는 상품 목록은 대중의 선호도를 반영하여 제공된다. 그러나 제공되는 상품 정보는 개인의 선호도와는 무관하다. 이 논문에서는 각 개인의 관심 상품에 대한 대중의 선호도를 분석하기 위한 내 외부 SNS 활용 기법을 제안한다. 제안된 시스템은 내 외부 SNS 모듈로 이루어져 있다. 내부 분석 모듈은 사용자가 지정한 두 개 상품의 비교를 통하여 커뮤니티 사용자의 선호도를 수집 및 분석한다. 외부 분석 모듈은 트위터(Twitter)를 활용하여 그룹 및 타인의 니즈를 분석할 수 있도록 지원한다. 구현 결과 기존의 쇼핑몰과 달리 개별 사용자의 선호도에 따라 상품을 추천할 수 있음을 보였다. Shopping patterns are changing with the emergence of SNS. Recently, it is also interested in providing the information based on the users' needs. Generally, the provided information is obtained from the history of users' simple browsing. Best selling hot item list is also provided in order to reflect the preferences of public users. However, the provided information is irrelevant to an individual preference. In this paper, we propose a method to utilize inner and outer SNS for analyzing public preferences about goods which are interested by individual users. The inner analyzing module collects and analyzes the preferences of community members about two goods designated by individual users. The outer analyzing module supports to analyze public preferences by using the tweeter SNS. The results of implementation show that it is possible to recommend goods based on the individual users' preferences unlike the existing shopping mall.

      • KCI등재

        골반강에 발생한 유방형 근 섬유 모 세포종: 증례 보고

        박성훈,이일기,김성훈,신지열 대한영상의학회 2009 대한영상의학회지 Vol.60 No.3

        Mammary-type myofibroblastoma is very rare, benign mesenchymal neoplasm that’s composed of spindleshaped cells with features of myofibroblasts, and these cells are embedded in a stroma with hyalinization. The most common location of the tumor is the inguinal area and to the best of our our knowledge, there has been no such case that this type of tumor has presented as a pelvic space mass. We report here on a very rare form of mammary-type myofibroblastoma and we include the ultrasound and CT images. 유방형 근 섬유 모 세포종은 방추형세포들와 근섬유모세포들이 유리질화된 기질로 둘러싸인 매우 드문 양성 간질종양이다. 주로 서혜부에서 발견되며 저자들이 알기에 골반 강 내의 종괴의 형태로 발견된 경우는 없었다. 저자들은 매우 드문 형태의 유방형 근섬유 모 세포종을 경험하였기에 그 초음파와 전산화단층촬영소견을 보고하는 바이다.

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