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신석철 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2
For the purpose of grasping the characterestics of personality of the students of Boys' Camp, author applied the Korean version of Personality Deviance Scale to the students of Taejon Boys' Camp from April to July, 1986. And attempted factor analytical study using the SPSS/PC^+. The results of factor analysis were as follows: Factor 1 was Lack of Self-confidence factor. Factor 2 was Denigratory Attitude towards Other people factor. Factor 3 was Hostile Act factor. Factor 4 was Domineering Social Attitude factor. Factor 5 was Hostile Thought factor.
신석철,최하석 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2
This study was designed to examine cognitive function between organic mental disorder(OMD) patients and normal edlerly. First, the authors selected 41 OMD patients and 38 normal elderly, and then performed CAMCOG(Cognitive examination of CAMDEX) to them. Second, the authors selected not-different CAMCOG items between the two groups, and using SPSS/PC' performed factor analysis. The results were summarized as follows. 1. Seven factors were found out by factor analysis, and total variance of these factors were 64.1%. 2. Factor 1 was Praxis and Reading comprehension, Factor 2 was Language comprehension, Factor 3 was Unknown factor, Factor 4 was Language comprehension and expression, Factor 5 was Response to language, and Factor 6 was Expression of definitions. 3. Factor 1 was the most important factor, with eigen value 2.45, variance 17.5.
신석철,김정란,지익성 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
It has been known that mania in the elderly was a uncommon condition, but the incidence of first admissions for mania tends to increase with advancing age. The etiology of late-onset mania appears to be more heterogeneous, which including identifiable causes, especially brain diseases. The psychopathology of late-onset mania is often attenuated and less severe than in the young. Lithium remains the primary medication in mania in the elderly. However, certain anticonvulsants (valproic acid and carbamazepine) have a number of advantages, including a more tolerable as patients with secondary mania due to neurological and other medical disorders. We report a case of first-episode mania in 73-year old woman, who was treated with valproic acid for 2 weeks to attain stabilizing her symptoms.
만성 정신분열증에서 음성증상과 예후에 관한 임상적 고찰
신석철 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2
This study was attempted to clarify the effects of negative symptoms on the prognosis in chronic schizophrenia. 109 schizophrenic patients on screening schedule were applied the Scale for the Assessment of Negative Symptoms and Diagnostic and Prognostic Schedule. Overall level of disability after 12 months was classified in 3 groups as the group of improvement with less disability(56 patients), the group of no change(21 patients) and the group of detrioration with more disability(23 patients). To investigate the symptomatic differences among 3 groups, the author tried MANOVA using SPSS/PC+ based on the scores of each item. The results were summarized as follows: 1. Between the group of no change and the group of deterioration with more disability, the degree of affective flattening or blunting were significantly different at the level of P<0.05. 2. Between the group of no change and the group of improvement with less disability, and the group of improvement with less disability and the group of deterioration with more disability, the degree of affective flattening or blunting, avolition-pathy, anhedonia-asociality and attentional impairment and total assessment were significantly different at the level of P<0.05.
정신분열병에 대한 Risperidone의 효과 및 안전성에 관하여
신석철,왕성근,지익성,이선우,이규광,이봉희,이진영,황선희,신용재,배경도,김정란 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1
In order to evaluate the efficacy and safety of risperidone, 10 patients with chronic schizophrenia were examined for 8 weeks in a silgle-open study. After the wash-out period of 1 week, risperidone was administered. Efficacy was evaluated by means of Positive and Negative syndrome Scale for Schizophernia(PANSS) and Clinical Global Impression(CGI). Safety assessment included the Extrapyramidal Symptom Rating Scale(ESRS), vital signs, body weight, ECG, and laboratory tests. The results were as follows 1) On the PANSS total score, there was significant improvement of total score after 1 week (P<.05) of administratiom. 2) On the PANSS positive and negative subscal, there were significant improvement of posotive and negative scores after 2 weeks (P<.05) of administration. 3) On the PANSS general psychopatholgy subscals, there were significant improvement of general psychopathologyscores after 1 week (P<.05) of administratiom. 4) On the CGI, there was significant decreasement of clinical impression of severity of schizophrenia score after 2 week (P<.05) of administration. 5) A statistically significant increase in body weight (P<.05) was observed after 8 weeks of administration. 6) EPS reached the peak at the end of the 1st week of administration of risperidone (11.8± 24.25) but they were easily relieved by addition of benztropine and clonazepam. There was not significant change in laboratory tests, vital sign, ECG after 8 weeks of administration. These results suggest that Risperidone is an effective antipsychotics and clinically safe except for increased body weight in chronic schizophrenia.
정신분열증과 기질성뇌증후군 환자에 있어서 소인식 기능검사와 Tachistoscope에 관한 연구
신석철 충남대학교 의과대학 지역사회의학연구소 1982 충남의대잡지 Vol.9 No.2
Author tested mini mental state and tachistoscope of normal, schizophrenic and organic brain syndrome patients who was selected by research criteria of Feighner etc. And data was analyzed with stastical method. Result was summarized as followings; 1. Tachistoscope was not difference between normal and schizophrenic patients, but mini mental state was more impaired in schizophrenic patients than in normal persons. 2. Items of calculation and recall of mini mental state was more impaired in schizo-phrenic patients than in normal persons. 3. Tachisoscope. and toatal score and each item score of mini mental state was more impaired in organic brain syndrome group than in schizophrenic patients. And there was correlation between mini mental state and tachstoscope in organic brain syndrome patients.