兒童行動目錄(CBCL)에 의한 國民學生의 行動問題 調査

홍강의,송혜양,김중술,홍경자,박성수 大韓神經精神醫學會 1988 신경정신의학 Vol.27 No.2

This is an epidemiological study of emotional/behavior problems in Korean elementary school children(total 2,399 : 1.236 boys, 1,163 girls) by empolying Children's Behavior Check List(CBCL) developed by Achenbach and Edelbrock(1983), to which 3 problem items were added for this study. A test-retest reliability of CBCL was was assessed by computing the Spearman-Browm correlation and the average correlation among items was. 72. The interparent agreeement was also assessed and the average correaltion between mother and father was. 62. The study subjects were drawm by stratified sampling from 5 schools in Korea ; 3 schools (A, B, C) from Seoul, one school(D) from a medium size city one school (E) from a rural town. School C is located in upper/middle-upper class residential area, School A and D in middle class, and School B and E in lower-middle/lower class. The present paper reports the prevalence of behavioral/emotional problems in relation to sex, grade, locality and socioeconomic variables. Some of the major findings were as follows ; 1) The mean total problem score excluding 3 additional items was 27.28 and did not differ significanthy according to sex and locality(Seoul vs non-Seoul), However, the mean total problem scores were significanthy different from school to school. The lowest score was observed in children of School C(22.15), higher scores for School B(30.89) and E(30.64) and in-between scores for the School A(27.58) and D(25.47). Father's education also had significant effect on the total problem scores : 31.46 for elementary of less 27.79 for middle and high school and 23.05 for college or more. As for to the grade, mean total score was lowest for the first graders(22.12), increasing up until 4th grade(29.83), then decreasing for 5th graders(26.81) and then relatively high score for the 6th graders(29.81). 2) Examination of each 122 problem items revealed that prevalence rate ranged from 2.1% to 61.7% : less than 5% for 13% items, 5-10% for 18 items, 10-20% for 31 items, 20-30% for 25 items, 30-40% for 15 items, 40-50% for 13 items, more than 50% for 7 items. Although sex did not make any difference in total problem scores, examination of the prevalence of each item revealed that 47 problem items were significanthy different between sexes : 26 items were more prevalent in boys and 21 items in girls. The items more prevalent for boys were externalizing problems such as hyperkinetic, aggressive and other behaviors and 21 items, more prevalent for girls were internalizing problems such as emotional and psychosomatic problems. School grade had significant effect in 47 items, only 3 of which showed lower prevalence in the younger children and the prevalence of 39 items were higher in older children. Significant differences were observed in 83 items, and 94 items, respectively according to school and father's education that could be considered to reflect socioeconomic status and it was reavealed that the lower the status, the higher the prevalence in most items. Items more common in upper class tend to be more anxiety-tension related(internalizing) and items more common in lower class tend to be more aggressive, hyperactive and other behavioval problems(externalizing). 3) Brief cross-cultural comparisons between the current study and other studies reported in the literature revealed major differences in several areas. The total problem score for Korean children was much higher than those of American and Dutch children, but lower than those of Canada and Chile. Although most of other studies reported higher total problem scores for boys, than for girls there was no sex difference in total problem score for Korean children. This was reflected in the finding of an almost equal numbers of items(26 for boys, 21 for girls) being more common than the other sex. Analyses by grade(age) also indicate major differences between Korean and American-Dutch children ; In contrast to the finding that total problem score was higher and larger number of items were more common for younger children in American and Dutch studies, they were higher for older children in Korean study. Socioeconomic variables seems to exert far more significant effect on the total score and the prevalence of each items in Korean study, when compared with American and Dutch studies. Further analyses of the data including a comparison with a clinic sample are deferred to another paper and so are the factor analysis results of 122 items into emotional/behavioral syndromes.

폐머리카락을 이용한 중금속의 흡착특성에 관한 연구

홍승목,정진희,장나영,김한석,이기형,김명숙,성낙창 東亞大學校 附設 環境問題硏究所 2008 硏究報告 Vol.29 No.1

The current study conducted experiments for property analysis regarding heavy metal absorption, iodine adsorption and porosity using waste hair as a reclamation method of waste hair. The study also observed pore distribution of hair using a Scanning Electron Microscope(SEM) and examined the possibility of removing heavy metal from hair. That is, the purpose of the current study is to evaluate environmental risk and economical efficiency by comparing hair with other biomass resources, activated carbon, etc. heavy metal removal efficiency was analyzed wrule heavy metal concentration 10 ppm, time variables were 5min, 15min, 30min, 60min and 120min, temperature was 20 .C, and pH 3

트랙터부착형 배추수확장치의 설계요인

홍종태,최용,성제훈,김영근,이기영 한국농업기계학회 2001 바이오시스템공학 Vol.26 No.4

폐머리카락을 이용한 중금속의 흡착특성에 관한 연구

홍승목,정진희,장나영,김한석,이기형,김명숙,성낙창 동아대학교 환경문제연구소 2008 硏究報告 Vol.30 No.1

The current study conducted experiments for property analysis regarding heavy metal absorption, iodine adsorption and porosity using waste hair as a reclamation method of waste hair. The study also observed pore distribution of hair using a Scanning Electron Microscope(SEM) and examined the possibility of removing heavy metal from hair. That is, the purpose of the current study is to evaluate environmental risk and economical efficiency by comparing hair with other biomass resources, activated carbon, etc. heavy metal removal efficiency was analyzed wrule heavy metal concentration 10 ppm, time variables were 5min, 15min, 30min, 60min and 120min, temperature was 20 .C, and pH 3

Ba0.7Sr0.3TiO3 세라믹스의 소결온도, 성형압력에 따른 격자 뒤틀림과 유전 특성과의 관계

임성민,홍석민,박홍진,김옥경 한양대학교 이학기술연구소 2000 이학기술연구지 Vol.2 No.

소결온도와 성형압력을 각각 조절하여 Ba0.7Sr0.3TiO3 세라믹스의 결정립의 크기를 조절한 후 이에 따른 격자 뒤틀림의 변화와 유전특성과의 관계를 조사하였다. 소결온도와 성형압력이 증가함에 따라 결정립의 크기는 모두 증가하였지만 격자 뒤틀림은 소결온도가 증가함에 따라 감소하는 반면 성형압력의 증가에 대한 영향으로 증가하였지만 성형압력을 변화시킨 시편은 격자 뒤틀림의 변화와 마찬가지로 큰 변화를 나타내지 않았다. 유전변화율(dielectric tunability)은 성형압력을 변화시킨 시편이 소결온도를 변화시킨 경우보다 더 크게 나타났다. Ba0.7Sr0.3TiO3 ceramics with various grain sizes were prepared to investigate the lattice distortion dependence of dielectric properties by controlling sintering temperature and pressing. The grain sizes of the samples are increased with increasing sintering temperature and pressing pressure. The dielectric constant is increased by increasing sintering temperature due to the decrease in lattice distortion while it is not much affected by controlling pressing pressure. The sample made by controlling pressing pressure have greater dielectric tunability than those made by controlling sintering temperature.

발달장애 발생요인의 예측과 장애아동 가족의 복지모형 개발연구 Ⅱ : DCRW 인과모형 DCRW Causation Model

정영숙,이상복,정보인,홍강의 한국정서학습장애아교육학회 2001 정서ㆍ행동장애연구 Vol.17 No.2

The purpose of this study was to identify potential risk dimensions for children with developmental delay or at-risk children and to establish family welfare model showing cause-and-effect relationship. This study assumes that the presence of children at risk may be considered a potential stress factor for the families, and the family's perception of their situation influences the degree of distress experienced by the family and copying strategies. Data were factor analyzed, and the results revealed four different risk dimension types : impulse-aggressive, physical-immature, cognitive-immature, social-immature dimension. Applying three structural equations for the causes of the three endogenous variables, hypothesized DCRW causal diagram for family welfare model in this study was proved, implying that higher risk dimensions of children's behavior increase family stress and the negative perception of their situation. Also, the path coefficients showed that family welfare were directly and indirectly influenced by the risk dimensions of children's behavior, family environmental variables (i. e, family stress, perception of situation, copying strategies), and family risk. Similarities and differences in risk dimension types are discussed, and implications for family welfare are provided.

함량별 DBP 스폰지에서 골수간엽줄기세포를 이용한 조직공학적 골분화 유도

홍희경 ( Hee Kyung Hong ),김순희 ( Soon Hee Kim ),이선경 ( Seon Kyoung Lee ),김대성 ( Dae Sung Kim ),최진희 ( Jin Hee Choi ),이동원 ( Dong Won Lee ),이종문 ( John M Rhee ),손영숙 ( Young Sook Son ),강길선 ( Gil Son Khang ) 한국조직공학·재생의학회 2009 조직공학과 재생의학 Vol.6 No.4

Demineralized bone particle(DBP) that affects to cell proliferation and differentiation has been used as biomaterials. Bone marrow stromal cells(BMSCs) exhibit multiple traits of a stem cell population, and they can expand many times in vitro and be induced to differentiate into multiple cell types. In this study, we evaluated the effect of type of medium and contents DBP sponge on bone differentiation of rat BMSCs. Growth medium was consisted of DMEM, 10% FBS, 1% antibiotic antinycotics and Osteogenesis medium added to β-glycerophosphate 10 mM, L-ascorbic acid, dexamethasone 10-8 M, vitamin D3 10-8 M. DBP sponge were prepared by freeze-drying method from 1, 2 and 3 wt% DBP solution. BMSCs were harvested from the femurs of adult female Fischer rat. The effect of DBP sponge on the proliferation and ostegenesis of rat BMSCs were assessed in culture using the MTT assay, SEM, ALP assay, and RT-PCR was conducted to confirm mRNA expression of ALP and osteocalcin for osteogenic marker. According to our results, the cell viability and the quantity of ALP in 3 wt% DBP sponge were superior to other sponges. The osteogenesis medium provided the better osteogenesis effect than the growth medium. We concluded that osteogenesis medium and 3 wt% DBP sponge will be useful to bone differentiation using 3 wt% DBP sponge.

Cloning and expression of the insecticidal toxin gene “tccB” from Photorhabdus temperata M1021 in Escherichia coli expression system

Eun-Kyung Jang,정병권,Gun-Seok Park,Abdur Rahim Khan,Sung-Jun Hong,박영준,WON-CHAN KIM,JAE-HO SHIN,Khalid M S Al-Ghamdi,Bassam Oudh Al-Johny,Yasir Anwar,Muhammad Faisal Siddiqui,Ihsan Ullah 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.1

Photorhabdus spp. has a high molecular weight Tc toxin with insecticidal activity. These toxins have been suggested as an alternative to BT toxin from Bacillus thuringiensis. Herein, we constructed a cosmid library with the genome of M1021 and screened the Escherichia coli clones showing insect toxicity by injecting each clone into Galleria mellonella larvae. In a total of 1020 clones, one clone with high insecticidal activity was selected and the nucleotide sequence of the cosmid of the clone was determined. In cosmid PtC28, a gene with 87% homology to the tccB gene of Photorhabdus temperata was found. Consequently, we have isolated the tccB gene cassette from the M1021 and expressed in E. coli expression vectors. The toxin was produced in the form of inclusion bodies but the denatured and refolded recombinant TccB showed strong mortality to the G. mellonella larvae.

아시클로비어 고체분산체의 용해도에 대한 수용성 고분자의 종류 및 배합 비율에 따른 효과

안용산,이하영,홍금덕,정성범,조선행,이종문,이해방,강길선 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.4

Acyclovir (ACV) is one of the most effective and selective agents against viruses of the herpes group. Because of low solubility, bioavailability of ACV has shown below 30% with oral dosage form. In our previous study, we reported that the fabrication of solid dispersion of ACV was possible and the solid dispersion of ACV and PVP was the most useful in all samples. In this study, we examined the effect of mixture ratio of polymers (PEG and PVP) to ACV. Solubility of ACV was dramatically increased up to 25 mg/ml in 80°C distilled water. So water was used as a solvent to eliminate problem of residual solvent. Spray drying method was used for the solid dispersion of ACV as solvent extraction. Different scanning calorimeter was used to check degradation of drug. Polymer carriers were PEG 6,000 and PVP. In summary, ACV-PVP (1:3) showed the best solubility in distilled water.

서울지역 4년제 간호대학생들의 임상실습 유,무에 따른 진로태도성숙

권혜진,김보람,김소연,김수임,성정아,신영미,윤서진,이경진,홍영선,이자형,정덕유,신혜원 이화여자대학교 간호과학대학 2009 이화간호학회지 Vol.- No.43

This study was conducted to investigate the differences in the degrees of career attitude maturity according to the clinical practice experience of the college of nursing students. The convenience sample was 275 students attending the college of nursing in Seoul. Data was obtained through a questionnaire from December 1st to 12th, 2008. The instrument used to measure the career attitude maturity in this study was "A barometer of maturity in career attitudes" developed by Ki-hak, Lee(1997). The collected data were analyzed by descriptive statistics, Chronbach's alpha, t-test and ANOVA with the SPSS 16.0 program. Below is the result of this study. 1. The average score for career attitude maturity of nursing students who experienced clinical practices was 135.56(±12.17): higher than the average score of inexperienced students, 134.37(±12.44). However it could not show meaningful differences in the statistics(F=-.805, p=.422). 2. Determinacy, one of five subordinate concepts of career attitude maturity, was statistically significative. On average, the group comprised of students with clinical practices scored 27.60(±3.81): higher than that of unpracticed students, 26.63(±4.26)(F=-1.976, p=.049). 3. The more academic years they have, except for junior year students, the points of career attitude maturity relative to general characteristics were increasingly higher. The points were 132.60(±11.99) for freshmen, 135.93(±12.72) for sophomores, 133.50(±12.57) for juniors and 138.11(±11.24) for seniors(F=2.714, p=.045). 4. According to the age of the group, the grade of career attitude maturity became higher. The scores were 133.21(±12.34) for 18-19yrs., 134.05(±12.16) for 20-22yrs., 138.43(±10.96) for 23-26yrs. and 148.71(±12.76) for 27-32yrs. (F=5.118, p=.002). 5. The average total score for career attitude maturity of nursing students was 135.00(±12.30). Of the five subdivisions―readiness, conviction, determinacy, independence and finality― readiness demonstrated the highest result with 32.33(±4.46) followed by conviction, determinacy, independence and finality respectively. Based on the results, there are some proposals for further researches. As this research was only for college of nursing in Seoul, it is necessary to compare career attitude maturity with 3-year colleges and other departments. In addition, alongside clinical practices there is a growing need to develop programs that will not only provide guidelines but also prepare students for the maturity of their career attitude.