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        2007년 대한감염학회 권장 성인 예방접종 권장안

        강진한,김홍빈,손장욱,이상오,정문현,정희진,최영화,최정현,최준용,최희정 대한감염학회 2008 감염과 화학요법 Vol.40 No.1

        In 2007, the Korean Society of Infectious Diseases recommended an immunization schedule for adults residing in Korea. This recommendation includes four categories: standard immunization for healthy persons, supplementary immunization for persons with underlying illnesses, recommendations for health-care personnel and for international travelers. The Standard Immunization Schedule consists of universal vaccination (tetanus-diphtheria/tetanus-diphtheria-pertussis (Td/Tdap); hepatitis A vaccine for persons aged 20s; human papilloma virus vaccine for women under 26 years old; meningococcal vaccine for military recruits and college students in dormitories; influenza vaccination for persons aged 50 years or more and pregnant women; and pneumococcal vaccination for persons aged 65 years or more) and catch-up vaccination (hepatitis A vaccine for persons aged 30s; hepatitis B vaccine, varicella and MMR vaccines for persons who have uncertain specific immunities). The Supplementary Immunization Schedule recommends 4 vaccines, i.e., pneumococcal, influenza, meningococcal, and Haemophilus influenzae type b, appropriate to the underlying illnesses, and confirmation of the presence of antibodies to hepatitis A and hepatitis B. The Recommendation for Health-Care Personnel includes universal vaccination (influenza and pertussis) and catch-up vaccination (hepatitis B, measles-mumps-rubella and varicella for seronegative health-care personnel). The Recommended Immunization for International Travelers focuses reinforcement of vaccinations for healthy persons and includes certain immunizations necessary for international travel (yellow fever, meningococcal, plaque, tick-borne encephalitis, and cholera). These guidelines can be seen at www.ksid.or.kr.

      • 酵母細胞의 인산대사 및 유기물 합성에 미치는 무기인산 화합물의 영향

        崔榮吉,이기성,李鍾三,趙善姬 漢陽大學校 環境科學硏究所 1983 環境科學論文集 Vol.4 No.-

        효모의 개체군 생장에 미치는 인산 화합물(??) 및 ??, ?? 양이온의 영향을 측정한 결과, ??는 Knopp씨 배지수준의 1배, 10배, 50배 처리의 전구간에 걸쳐서 개체군 생장에 유의한 촉진효과를 볼 수 없었다. ?? 처리구에서는, ?? 의 1배 처리구에서 대조구에 비하여 뚜렷한 생장촉진효과를 볼 수 있었으나, 10배, 50배의 처리구에서는 오히려 생장이 감소함을 나타내었다. 또한 ?? 처리구는 전 구간에 걸쳐서 대조구에 비하여 뚜렷한 억제가 관찰되었다. 한편, 효모의 인산화합물 합성에 미치는 영향을 측정하여 본 결과, ??의 경우는 산 가용성 Total-P 가 전 구간에 걸쳐 배양 처리후 6일째에, 대조구에 비하여 증가하였으며, ??처리구는 전처리구에서 산가용성 Total-P가 감소하였으나 ortho-P만은 증가하였음을 보였다. ??의 처리구에서도 Total-P는 역시 대조구에 비하여 감소하고 ortho-P는 대조구와 비슷한 경향을 보였다. poly-P "A", "B", "C", type 의 소장 관계를 측정한 결과, poly-p-A 와 B는 인산농도 및 양이온의 농도가 높을수록 많은 생성량을 나타내었으며, 특히 ?? ×50 처리구에서 poly-p-"B" 의 최대 합성량을 볼 수 있었다. 또한 여러 배양조건하에서도, 여러가지 poly-P 전환과정은 모든 시험구에서 동일한 것으로 나타났다. 그리고 특히 ?? 이온에 의해 영향받는 poly-P의 유기물합성에 이용되는 전환경로와 poly-P 상호 전환경로는 다음의 관계가 성립하는 것으로 추론된다. ?? 한편, 효모세포의 단백질, 핵산, 인지질, 탄수화물 합성에 미치는, 이들 인산 화합물의 양적 동태를 고찰한 결과, 핵산의 경우, ?? 처리구는 모든 구간에서 핵산 합성에 유의한 효과를 찾을 수 없었으며, ??처리구는 1배농도의 처리구에서는, 핵산의 합성증가를, 그외의 처리구에서는 합성량이 낮았다. ?? 처리구에서는 전체적으로 현저한 유기물의 합성억제를 나타내었다. 단백질 합성의 경우는 ??×1처리구를 제외한 모든 처리구에서 대조구와 비교하여 비슷한 경향을 나타내거나 억제효과를 보여주었을 뿐,촉진효과를 관찰할 수 없었다. 인지질 합성시 ??는 촉진효과를 나타내었으나 ?? 와 ?? 는 유의한 효과를 볼 수 없었다. 효모의 탄수화물 합성에 있어 ?? 는 대체로 대조구의 합성량과 유사하며, ?? 의 경우와 ??의 경우는 전 처리구간에서 대조구에 비하여 배양초기에 억제효과를 나타내었으나, 배양후기에는 오히려 증가되었다. 한편 poly-P와 유기물 합성과의 상관관계에서, Polysaccharide,lipid-p, DNA 합성에는 Poly-P-B가, nucleotidic-labile-P 생성에는 poly-P-C 가 상호 연관된 것으로 추정되었다. Examined the effect on the growth of yeast population by treating medium with phosphate compounds such as ??, ?? and ?? ion as the the concentration of Knopp's level, tenfold concentration and of fiftyfold, respectively, it could be recognized as the following facts; in case of ??, it showed no significant effect on the growth of yeast population in all treatmemt. And in case of ?? treatment replaced K? of KH₂PO₄in knopp's medium it showed the stimulating effect in the culture as comparing with those of control, but on the contrary, it was revealed the inhibition effect in the culture of tenfold and fifty fold treatment. However, the addition of ?? compounds showed the clear evidence of inhibition effect in population growth. Measuring the effect on the synthesis of phosphate compounds of yeast cell by treating the above chemicals, the amount of acid soluble-total phosphate was increased in all ?? teatment on 6th day after treatment. On the contraty, in case of ?? treatment, the amount of acid soluble-total phosphate was decreased in all treatment comparing with that of control, but the amount of ortho-phosphste was increased in all cultures. These similar tendencies were also found in the cultures of As?? compound treatment. The amount of acid soluble-total phosphate was decresed comparing with that of control and ortho-phosphate was as of control level. The accumulation amount of each type of polyphosphate(A,B and C) seemed to have a relationship between each other. It seemed that the amounts of polyphosphate A and B in yeast cell are increased in accordance with high cation concentration and phosphate concentration in culture medium. Especially, the culture in fiftyfold concentration of ?? ion synthesized the highest amount of polyphosphate B. However, the trun-over patterns of each polyphosphate under various conditions showed similar tendencies with each other. But the patterns utilizing in synthesis of cellular organic matter are belived to be affected by ?? ion as the direction in the following figure. ?? The synthesis of cellular organic matter, such as protein, nucleic acid, phospholipid , and polysaccharide was also belived to have a relation to cellular nutritional conditions. Any treatment of ?? showed no significant effect in synthesis of nucleic acid . The treatment of ?? compounds was resulted in decreased of nucleic acid generally, but increase in the culture replaced ?? of KH₂PO₄of Knopp's medium by ??. However, all the treatment of ??) compounds to medium showed strong inbibition effect in synthesis of nucleic acid. The synthesis of cellular protein is promoted by treating ?? compounds as Knopp's level. but in case of tenfold and fiftyfold concentration, the amount of protein is equivalent to or below to that of control. Referring to synthesis of phospholipid, ?? treatment was effective, but ?? and ?? compounds showed inbibition effect. The amount of carbohydrate in yeast cell treated by ?? is similar to those of control, however, in the cell treated by ?? or ?? compounds, the amount was increased just after decreasing in early stages of incubation. The relationship between each polyphosphate and synthesis of cellular organic matter could be interpretated that polyphosphate B is utilized mainly in synthesis of polysaccharide, phospholipid and DNA, and that polyphosphate C is also related in formation of nucleotidic labile phosphate.

      • 고령토로부터 알루미나 추출에 관한 연구(Ⅲ):염산에 의한 추출

        최세영,이용근,이희수,김형국 연세대학교 산업기술연구소 1992 논문집 Vol.24 No.1

        The preparation conditions of alumina powder extracted by hydrochloric acid from domestic San-Cheong kaolin have been investigated. In order to obtain best conditions to extract alumina by hydrochloric acid, experiments carried out with various acid concentrations, reaction temperatures, reaction times, and pH. The optimum conditions were 20 wt.-% for hydrochloric aicd concentration, 100℃ for reaction temperature, 7hrs for reaction time and pH8. The yield of alumina found to be 89.2wt.-% under these conditions. Two drying methods, direct and ethanol distillation drying method to control the precipitated agglomeration have deen compared. The ethanol distillation drying method revealed more narrow particle size distribution and less agglomerate than the direct drying method.

      • 양측성 관상동정맥루 1예

        최용원,오석규,이재훈,이상재,권경희,최은경,김남호,정진원 圓光大學校 醫科學硏究所 2002 圓光醫科學 Vol.17 No.1

        저자들은 호흡곤란, 흉부불쾌감, 심계항진 등을 주소로 내원한 환자에서 경흉부 및 경식도 심초음파 검사상 주폐동맥에서 이완기에 전행하는 지속적인 혈류의 흐름을 관찰하고, 관상동맥 조영술을 통해 좌전하행지 중간부위와 우관상동맥 근위부에서 각각 기시하여 공통경로를 이루면서 주폐동맥으로 유입되는 양측성 관상동정맥루를 보이는 드문 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. A coronary arteriovenous fistula is infrequently encountered vascular communication between a coronary artery and a cardiac chamber, a great artery or the vena cava. It is the most common congenital anomaly that can affect coronary perfusion. Bilateral involvement of coronary fistula constitutes an uncommon subgroup of coronary arteriovenous fistulas. A 69 year-old female patient presented with chest discomfort, palpitation, and dyspnea. In the echocardiography, doppler color flow imaging visualized abnormal flow signals with mosaic appearance in the main pulmonary artery during diastolic phase. Coronary angiography revealed arteriovenous fistula arising from the left anterior descending artery and the right coronary artery. Both coronary arteriovenous fistulas drained into the main pulmonary artery. We report a case of bilateral coronary arteriovenous fistula that was confirmed by echocariography and coronary angiography.

      • SCIESCOPUSKCI등재
      • KCI등재

        삼부이론을 적용한 창의적 사고 배양 수업안의 개발 : 지구과학 분야를 중심으로 Especially for High School Earth Science Education

        최임조,임영구,강용희,유계화 慶北大學校 科學敎育硏究所 2003 科學敎育硏究誌 Vol.27 No.-

        The enrichment triad model(Renzulli, 1977) which was originally developed for teaching and learning of gifted and talented children consists of three types of enrichment activities. Type Ⅰ enrichment activities build knowledge for later use in 'gifted behaviors', and type Ⅱ enrichment activities focus on the 'how-to skills,' attitudes and values the student must develop to become and effective investigator, problem solver and producer. Type Ⅲ enrichment activities, the pursuit of real problems and realization of gifted behavior, are the fundamental goal for this model. In this study we developed enrichment activities for high school earth science class. We could summarize enrichment activities as follows: In studying the fossil section, after reporting their research activities on fossil data, students can understand the fossil theory through questioning and answering their homeworks. They can enhance their interest and curiosity by watching the movie 'Jurassic Part'(type Ⅰ enrichment activities). After making replica of fossil samples(type Ⅱ), they can write their research reports or articles concerning fossils(type Ⅲ). Students can extend their knowledge about fossils through these types of enrichment activities. In studying weather map section, after collecting newspaper clippings or searching internet, students present their knowledge about weather and weather maps(type Ⅰ enrichment activities). Learning how to make weather maps and investigating how to analyze them, student can extend their knowledge(type Ⅱ). Through these activities, students can apply their knowledge to everyday life experience(type Ⅲ). The third program is 'igneous rock' section. Students investigate the fossil formation in Korea(type Ⅰ enrichment activities). They can understand the principle of volcanic activities through experiment of volcano eruption model type Ⅱ. Through drawing pictures, writing assignment of experiment activities and playing the role play of igneous rocks, teachers can help students to acquire cause or interest to study the igneous rocks(type Ⅲ). In conclusion, within a classroom instruction teachers would be utilizing all three types of activities, moving from one to the other as class, and individual needs, demand. By selecting what students want to do and making them to produce results of their activities, we are expecting that teachers can cultivate creative thinking and enhance problem solving ability of students.

      • 鹽化物 含有梁에 따른 鐵分 腐蝕에 관한 實驗的 硏究

        최진석,조철희,신용석,고송균,손순채,김정섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

        As a result of separating river sand and sea sand into the corrosion increased according to the of thinnss or the coating and the Chloride Content and Corrosion of Steel Bar through the experiment, the following conclusions are obtained. 1. There was no corrosion in the case of treating the steel bar with anticorrosive among test specimens cured in the air for 60 days, corrosion was found in the test specimens not treated with anticorrosive and for 60 days of age. 2. The area of corrosion increased according to the thinnss of the coating and the chloride content wher exposed for are more than 60 days. Therefore, it was determined in general that the corrosion progressed more rapidly in water cured specimens than in air cured ones and this was due to the influence of C1_( ̄) in the sea sand.

      • T cell epitope 차폐에 의한 b_(4) peptide 면역응답방응에 대한 연구

        최정순,이희종,공수강,리투,류용구,김효준 한양대학교 이학기술연구소 2005 이학기술연구지 Vol.8 No.-

        Apo B-100 is a constitutive component of low density lipoprotein (LDL) of which functions in packaging, transport and absorption of lipids Extortive binding of anti B_(4)-antibody onto the Apo B-100 should inhibited the functions of Apo B-100 Previously we had showed that the peptide B_(4) induced antibodies recognized Apo B-100 and thus elicited anti-obesity effect In this study we compared the efficacy of antibody inducing immune responses by introducing additional peptides fused to the C-termninal of B_(4) peptide We constructed TB_(4) hybride peptide of B_(4) with preS2 of HBV and B_(4)N another epitope orientation of chimeric TB_(4) Among these three artificial peptides B_(4)N was the most efficient inducer of the antibody against B_(4) These result explains that the B cell epitope and T-helper cell epitope orientation is very important factor to determine the antigenicity to humoral immunity. Apo B-100은 LDL에서 지방을 포장, 흡수, 운반하는 기능을 수행하는 단백질이다. Apolipoprotein B-100(Apo B-100)에 대한 특이 항체의 결합은 LDL의 정상 기능을 방해한다. 선행 실험에서 Apo B-100의 모조 펩타이드인 B_(4)가 Apo-B-100을 교차 인식하는 항체를 유도하고, 비만 억제 효과를 나타내는 것으로 밝혀졌다. 본 연구에서 B_(4)펩타이드의 C-terminal부분에 펩타이드를 융합, 첨가하므로 면역반응에서 항체유도의 면역응답반응에 어떠한 효과를 나타내는지 비교해 보고자 하였다. B_(4)펩타이드의 N-말단에 HBV의preS2 펩티드를 융합시킨 B_(4)T의 N-말단데 또다른 B세포 에피도프 펩티드를 융합시킨 B_(4)N을 작성하였다, 세종류의 하이브리드 펩타이드 중에서 B_(4)N이 B_(4)에 대한 항체유도능이 가장 효율적이다,. 이상의 결과로 B cell epitope과 T-helper cell epitope의 방향성이 체액성 면역 반응에서 항원유도능을 결정하는 중요한 요소임을 확인하였다.

      • 무선전력전송을 위한 RF-DC 변환기 회로의 성능비교

        최기주,황희용 江原大學校 産業技術硏究所 2009 産業技術硏究 Vol.29 No.B

        A RF-DC converter is one of the most important components for a wireless power transmission. It has been developed for many applications such as space solar power system, and Radio Frequency Identification(RFID). In this paper, we designed three types of RF-DC converter and compare the performance of each. All types RF-DC convertoer have a maximum conversion efficiency at input power level of 0 dBm~5 dBm and RF-DC converter of third type was the best performance that has a 21.9% of conversion efficiency.

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