http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
장시간 수술시 Propofol과 Enflurane의 마취 유지 효과 및 술후 각성도에 대한 비교
김태요,윤재승,이강창,정영표,안선연 圓光大學校 1995 論文集 Vol.30 No.2
There has not been particular attention focused on the comparative benefits and risks of propofol anesthesia with inhalation anesthesia in the operations of long duration. This study was assessed the anesthetic efficacy and the speed of recovery from propofol or enflurane anesthesia in patients undergoing the long term operations. The propofol group (n=25) receiver 2.0 - 2.5mg/kg propofol intravenously for the induction of anesthesia and followed by propofol infusion(6 - 12mg/kg/h). The enflurane group (n=25) was induced as the propofol group and followed by enflurane(1-2 MAC) addministration. All patients received nitrous oxide (50%) in oxygen immediately after tracheal intubation. All anesthetic agents were stopped at the time of last stitch. The hemodynamic changes were recorded and the recovery was assessed with the time from discontinuation of all anesthetics to extubation and the indices of consciousness at early recovery(recall name, eye opening on command, raise hand on request and coughing on request). The recovery tests showed no differences between the groups. Systolic pressure after intubation in propofol group was significantly increased (p<0.05), compared with enflurane group. In propofol group, seven patients received fentanyl because of light anesthetic depth. The frequency of nausea and vomiting was similar between the groups. In conclusion, the long propofol anesthesia was not associated with faster recovery than enflurane anesthesia and propofol as an agent of anesthetic maintenance was unfavorable.
알카리성 부여제 도포에 의한 중성화된 콘크리트의 알카리성 회복성능에 관한 실험적 연구
김무한,권영진,강석표,유재강,이강우 충남대학교 산업기술연구소 2000 산업기술연구논문집 Vol.15 No.1
Concrete is the most commonly used material in construction field and it is the permanent construction material with respect to civil property. But, if concrete loses its alkalinity by CO2 gas, it loses its structural characteristics and results in total collapse in construction field. Therefore. it is needed to be studied the alkali-recovery performance by alkalization agent on carbonated concrete by accelerated carbonation test. In this paper, we investigate recovery performance by impregnating alkalization agent in carbonated concrete, then we evaluate alkali maintenance performance by pH survey in each kinds of finishing materials. The results of this paper can be summarized as follows. 1)Carbonated concrete under pH 10 was recovered its alkalinity to pH 11 at first stage by spreading alkalization agent on its outer surface. 2)After spreading alkalization agent, there is a difference due to types of moreover effect of anti-rust paint and ordinary cement paste were excellent.
조강표,정진택,정명채,김윤석 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)
Wind load is evaluated based on Standard Design Loads for Building of AIK(Architectural Institute of Korea), which was obtained from wind-tunnel experiment for an isolated building in open country, actual wind load can be different from the code because of terrain, building geometry, wind direction, separation distance between the buildings. Among them. separation distance is the most important factor. This paper presents the interference factor for sqaue section high-rise building structure, focusing on the separation distance. Interference factor was obtain from the force balance test in a wind tunnel.
한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률
조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4
Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.
Kang, Chan Woo,Jang, Kang Won,Sohn, Jinyoung,Kim, Sung-Moo,Pyo, Kyoung-Ho,Kim, Hwan,Yun, Mi Ran,Kang, Han Na,Kim, Hye Ryun,Lim, Sun Min,Moon, Yong Wha,Paik, Soonmyung,Kim, Dae Joon,Kim, Joo Hang,Cho, American Association for Cancer Research 2015 Molecular Cancer Therapeutics Vol.14 No.10
<P><I>RET</I> rearrangement is a newly identified oncogenic mutation in lung adenocarcinoma (LADC). Activity of dovitinib (TKI258), a potent inhibitor of FGFR, VEGFR, and PDGFR, in <I>RET</I>-rearranged LADC has not been reported. The aims of the study are to explore antitumor effects and mechanisms of acquired resistance of dovitinib in <I>RET</I>-rearranged LADC. Using structural modeling and <I>in vitro</I> analysis, we demonstrated that dovitinib induced cell-cycle arrest at G<SUB>0</SUB>–G<SUB>1</SUB> phase and apoptosis by selective inhibition of RET kinase activity and ERK1/2 signaling in <I>RET</I>-rearranged LC-2/ad cells. Strong antitumor effect of dovitinib was observed in an LC-2/ad tumor xenograft model. To identify the acquired resistance mechanisms to dovitinib, LC-2/ad cells were exposed to increasing concentrations of dovitinib to generate LC-2/ad DR cells. Gene-set enrichment analysis of gene expression and phosphor-kinase revealed that Src, a central gene in focal adhesion, was activated in LC-2/ad DR cells. Saracatinib, an src kinase inhibitor, suppressed ERK1/2 phosphorylation and growth of LC-2/ad DR cells. Taken together, these findings suggest that dovitinib can be a potential therapeutic option for <I>RET</I>-rearranged LADC, in which acquired resistance to dovitinib can be overcome by targeting Src. <I>Mol Cancer Ther; 14(10); 2238–48. ©2015 AACR</I>.</P>
( Kang Pyo Kim ),( Nam Woo Kwon ),( Beom Kyung Kim ),( Seung Up Kim ),( Do Young Kim ),( Sang Hoon Ahn ),( Kwang Hyub Han ),( Chae Yoon Chon ),( Jun Yong Park ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-
Background: With wide use of vaccination and antiviral agents against hepatitis B virus (HBV) infection, epidemiologic characteristics of HBV-infected patients have changed substantially for several decades in South Korea, however, recent data are lacking. Hence, we reviewed the recent clinical characteristics of patients with chronic hepatitis B (CHB). Methods: From January 2010 to December 2010, we studied 5,262 consecutive HBV-infected patients who visited in Severance Hospital. Data concerning demographic profiles, laboratory findings about viral activity, and antiviral therapy were gathered. Results: Among the whole population, the median age was 51.0 and 66.0% were male. 1,788 (34.0%) had positive HBeAg and the median ALT level was 31.0 (2, 4700) IU/ml and 1,560 (29.6%) patients had family history of HBV-related liver disease. Regarding viral replication status, 297 (5%) patients were in immune tolerance phase, 2,195 (42%) in inactive phase, and the remaining 2,770 (53%) patients were in active CHB (either immune clearance or reactivation phase). Liver cirrhosis was diagnosed in 2,065 patients, among them, 611 (29.6%) patients had positive HBeAg, and 576 patients had experienced decompensation events including ascites, variceal bleeding, and hepatic encephalopathy. Hepatocellular carcinoma was diagnosed in 1,268 patients. Patients with HCC increased as they get older, especially after age of forty for male and after fifty for female. The male patients had a significantly higher ratio of the HCC than female patients did (78.7% vs. 21.3%, respectively, p<0.001). Conclusions: The study result shows that epidemiologic characteristics of CHB are male, elder, HBeAg negative dominant. The further studies are required to investigate the overall epidemiology of HBV infection in Korea.
( Kang Pyo Kim ),( Nam Woo Kwon ),( Beom Kyung Kim ),( Seung Up Kim ),( Do Young Kim ),( Sang Hoon Ahn ),( Kwang Hyub Han ),( Chae Yoon Chon ),( Jun Yong Park ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Background: With wide use of vaccination and antiviral agents against hepatitis B virus (HBV) infection, epidemiologic characteristics of HBV-infected patients have changed substantially for several decades in South Korea, however, recent data are lacking. Hence, we reviewed the recent clinical characteristics of patients with chronic hepatitis B (CHB). Methods: From January 2010 to December 2010, we studied 5,262 consecutive HBV-infected patients who visited in Severance Hospital. Data concerning demographic profiles, laboratory findings about viral activity, and antiviral therapy were gathered. Results: Among the whole population, the median age was 51.0 and 66.0% were male. 1,788 (34.0%) had positive HBeAg and the median ALT level was 31.0 (2, 4700) IU/ml and 1,560 (29.6%) patients had family history of HBV-related liver disease. Regarding viral replication status, 297 (5%) patients were in immune tolerance phase, 2,195 (42%) in inactive phase, and the remaining 2,770 (53%) patients were in active CHB (eiher immune clearance or reactivation phase). Liver cirrhosis was diagnosed in 2,065 patients, among them, 611 (29.6%) patients had positive HBeAg, and 576 patients had experienced decompensation events including ascites, variceal bleeding, and hepatic encephalopathy. Hepatocellular carcinoma was diagnosed in 1,268 patients. Patients with HCC increased as they get older, especially after age of forty for male and after fifty for female. The male patients had a significantly higher ratio of the HCC than female patients did (78.7% vs. 21.3%, respectively, p<0.001). Conclusions: The study result shows that epidemiologic characteristics of CHB are male, elder, HBeAg negative dominant. The further studies are required to investigate the overall epidemiology of HBV infection in Korea.