간이식 환자에서 발생한 Aspergillus fumigatus에 의한 고관절염 1예

김탁,이상록,조오현,박기호,오련,이상오,김양수,우준희,김미나,최상호 대한감염학회 2008 감염과 화학요법 Vol.40 No.3

저자들은 간이식을 받은 환자에서 조직 배양 검사를 통하여 진단된 A. fumigatus에 의한 화농성 고관절염을 경험하였기에, 문헌 고찰과 함께 보고하는 바이다. Septic arthritis is an uncommon finding of invasive Aspergillosis. It can be caused by direct inoculation, Post-surgical infection, and hematogenous spread. Articular aspergillosis often involves the knee. A 49-year-o1d man who received a liver transplant in China on two months ago, due to liver cirrhosis caused by hepatitis B virus was admitted because of left side hip pain. Hip MRI showed joint effusion and bony destruction of the left hip and acetabulum. Incision and drainage was done and Aspergillus fumigatus was isolated from the resected tissue. After eight weeks of amphotericin B therapy, total hip replacement arthroplasty was done. Oral itraconazole 400mg/day was prescribed for six months after operation. The patient is now doing well without physical restriction.

기저질환이 없는 사람에서 발생한 Campylobacter fetus에 의한 재발성 심내막염 1예

전재범,정진원,김성혜,송문희,오형철,안성기,최상호,김남중,김양수,우준희,류지소 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

C. fetus 심내막염은 드물게 발생하는 질환으로 주로 면역능이 저하된 환자에서 발병하고 대동맥판을 침범하는 경우가 많으며 적절한 치료가 되지 않을 경우 치사율이 높다. 저자들은 기저질환이 없던 69세 남자에서 C. fetus 심내막염을 경험하였기에 문헌고찰과 함께 보고하는 바이다. 환자는 발열로 내원하여 시행한 혈액배양 검사상 C. fetus가 동정되었고 경식도 초음파 검사상 삼첨판에 증식증이 발견되어 심내막염 진단하에 ceftriaxone에 이어 meropenem으로 총 4주간 항생제를 투여받고 호전되었다가 한달 후 다시 재발하였고 판막부전 소견 진행하여 삼첨판 치환술을 시행받고 전신상태 호전되어 퇴원하였다. Campylobacter fetus is a rare cause of endocarditis. To date, only about 30 cases of C. fetus endocarditis have been reported mainly in the elderly with chronic underlying illnesses. Most cases showed tendency to involve aortic valve. This report describes a case of native tricuspid valve infective endocarditis in a 69-year-old man without any underlying disease. Despite adequate antibiotic therapy for 4-weeks, endocarditis recurred and leading to surgical valve replacement.

모바일 로봇의 지능제어

오세봉,심병균,Nguyen Van Quyet,한성현,박동준 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

This paper achieves a research about remote control of robot based on voice recognition. Through real-time remote control and wireless network capabilities of an unmanned remote-control experiments and Home Security / exercise with an unmanned robot, remote control and voice recognition and voice transmission are possible to transmit on a PC using a microphone to control a robot to pinpoint of the source. Speech recognition can be controlled robot by using a remote control. In this research, speech recognition speed and direction of self-driving robot were controlled by a wireless remote control in order to verify the performance of mobile robot controller.

전자패키지 μBGA 무연솔더와 무전해 Ni 도금층의 계면 접합특성

오용준,오성룡,신봉문 한밭대학교 생산융합기술연구소 2004 생산기반기술연구소 논문집 Vol.4 No.1

The morphology and thermal stability of the interfacial phases in the joints between Pb-free solder (Sn3.5Ag0.7Cu) and electroless Ni-P(14at%P) and electrolytic Ni under bumper metallizations (UBM) were investigated as a function of solid state aging. Samples were prepared by reflowing at 250℃, N_(2) atmosphere and aging in the range of 125 to 170℃ for up to 1000h. After reflow, the interfacial intermetallic compound(IMC) was mostly Ni_(3)Sn_(4) in the electrolytic Ni/solder joint. After relatively short aging time, the interfacial IMC on electrolytic Ni layer developed into the dual layer structure of Ni_(3)Sn_(4)(bottom) and Cu_(6)Sn_(5)(top). But IMC on electroless Ni-P layer were Cu_(6)Sn_(5) and changed into the dual structure only after long aging time of 1000h. The growth rate of IMC with aing was higher on electrolytic Ni layer than on electroless Ni-P. The different behavior of electroless Ni-P/SAC joint came from Ni_(3)P formation between IMC and electroless Ni-P layer which retards interfacial reaction through reducing the diffusion of Ni and Sn. The thickness of Ni_(3)P layer was propositional to that of IMC. For longer aging time, NiSnP layer was found at the interface between IMC and Ni_(3)P layer. Interestingly, in spite of low consumption rate of electroless Ni-P than electorlytic Ni layer by suppressing IMC growth, the interface of Ni-P/IMC was locally hollowed by the accelerated reaction of the Ni-P layer through local thickness reduction of Ni_(3)P and NiSnP layers. This reduced the effective remaining thickness of Ni-P layer.

SF-36을 이용한 농촌 노인들의 건강상태 평가

전진용,김상아,박웅섭,오미경,홍윤미 관동대학교 의과학연구소 2001 關東醫大學術誌 Vol.5 No.1

This study was conducted to understand health status by general characteristic, and to find out relationship between the general characteristics and rural elderly's health status. Health status was measured using SF-36(Medical Outcome Study Short From 36). The finding of this study were as follow; Mean scores of health status by sex were higher in male on physical function, social function and role limitation-emotion. The elderly educated more reported good health on physical function, role limitation-physical, vitality, bodily pain and general health than did the elderly educated less. The elderly who have disease reported bad health on social function, mental health and general health. Therefore we reviewed the evidence that sex, education and illness are associated with health status in the elderly, and that specific public health service that related such condition should be considered for the rural elderly.

코크스 폐수를 이용한 활성슬러지 모델 파라미터의 민감도 분석

오재일,이병준,심효영,최상교 대한상하수도학회 2002 상하수도학회지 Vol.16 No.3

Activated sludge model (ASM, IAWQ Task Group) was developed as a general mathematical model to express major biological processes in municipal wastewater treatment. Therefore this model could be applied for the design of a wastewater treatment plant and used for finding optimal conditions in plant operation. Since biological processes adopting biodegradation have been also used to treat lots of industrial wastewater such as coke's wastewater, it is worthy to examine the applicability of ASM on the industrial wastewater treatment. In order to evaluate this possibility, the sensitivity analysis of seven parameters (Y_H,μ_H, b_H, k_h, K_S, K_(O,H), K_x) in ASM was conducted with regard to the SCOD (soluble chemical oxygen demand) removal in coke's wastewater treatment. It has shown that μ_H (maximum specific growth rate) of ASM was the most sensitive one in the SCOD removal process, and relative sensitivity was decided in order of μ_H >> b_H, K_S > Y_H, K_(O,H), K_h, K_x, consequently. Based on the sensitivity analysis and calibration procedure of ASM with the data from coke's plant, the decided parameter values were valid for the proper simulation of this industrial wastewater plant, showing adequate fitting between real and simulated data. In summary, the mathematical model of ASM was suitable for the simulation of coke's wastewater treatment plant.

당뇨병과 동반된 화농성 간농양의 임상상 및 예후인자

오은숙,강무일,이원영,오기원,임동준,이소영,이정민,고승현,김성래,안유배,손현식,윤건호,차봉연,이광우,손호영,강성구 대한당뇨병학회 2000 임상당뇨병 Vol.1 No.1

연구배경: 감염질환은 혈관질환과 함께 당뇨병의 중요한 사망원인의 하나이며, 혈당조절이 불량할수록 감염 빈도가 증가됨은 잘 알려져 있다. 간농양의 발생이 있어서도 당뇨병은 중요한 기저질환 중의 하나이다. 일반적으로 간농양의 가장 흔한 원인균은 Escherichi coli라고 알려져 있으나, 최근 당뇨병을 가진 간농양 환자에서 Klesiella pneumoniae의 검출이 증가되고 있다. 또 최근 연구에 의하면 K.pneumonie가 간농양의 가장 흔한 원인균이며, K. pneumoniae에 의한 간농양은 K.pneumoniae 이외의 균주에 의한 간농양보다 당뇨병과 밀접히 관련되어 있다고 보고된 바 있다. 이에 저자들은 간농양 환자를 대상으로 당뇨병환자의 빈도를 알아보고, 그 원인균 및 특징을 비당뇨병 환자들의 경우와 비교해 보고자 하였다. 방법: 1992년 1월부터 1999년 6월까지 방사선학적 검사 혹은 수술에 의해 간농양이 확인되거나, 경피적 천자나 수술을 통한 배농액 배양, 혹은 혈액 검사에서 원인균이 증명된 182명의 환자를 대상으로 후향적 임상고찰을 실시하였다. 결과: 화농성 농양을 가진 167명의 환자(남:94명, 여:73명)중 당뇨병을 가진 환자는 54명 (남:30명, 여:24명)으로 32.3%를 차지하였다. 환자의 평균나이는 당뇨군에서 62.1 ± 13.4세, 비당뇨군에서는 55.1 ±15.5세로 당뇨군에서 높았으며(p=0.0021), 남녀간의 평균나이 비교 시 두 군 모두 여성의 나이가 의미있게 높았다. 비당뇨군에 비하여 당뇨군의 경우 저알부민혈증의 빈도와 aspartate transaminase가 증가되어있었다. 원인균주는 K. pneumoniae (당뇨군54%, 비당뇨군 39.1%), E. coli(당뇨군 17.5%, 비당뇨군 18.8%), Pseudomonas aeruginosa, Streptococcus viridans, Enterococcus 순이었으며 두 군간의 의미는 차이는 없었으나 K. pneumoniae의 경우 다른 균종에 비해 단독감염의 빈도가 높았다(82.8%). 사망률은 당뇨군에서 16.7%, 비당뇨군에서 7.1%로 당뇨군에서 의미있게 높았으며(p=0.019), 당뇨군에서의 사망환자는 모두 패혈증이 동반되어 있었다. 당뇨환자의 사망군은 생존군에 비해 당뇨병 이환기간이 길고 혼합감염의 빈도가 높았다(p=0.046). 검사실 소견에서는 총 빌리루빈 및 알카리성 포스파타제의 증가가 관찰되어 있었다. 결론: E. coli가 간농양의 주된 원인균이라는 기존 보고와는 달리 당뇨군과 비당뇨군 모두 K. pneumoniae가 간농양의 주된 원인균이었다. 또한 당뇨 유병기간이 길고 당뇨조절이 불량한 환자에서 혼합감염이며 총 빌리루빈 및 알카리성 포스파타제의 증가등과 같은 위험인자가 존재할 경우 사망률이 증가될 수 있으므로 이들 군에서는 적극적인 치료가 필요할 것으로 사료된다. Background: Liver abscesses are commonly associated with underlying disease, particularly diabete mellitus. The number of the liver abscesses caused by Klebslella pneumoniae in diabetic patient has been increased in Korea nowadays. This study was conducted to clarify the clinical presentation and prognostic factors of pyogenic liver abscesses, especially in diabetic patients and to determine the proportion of K. pneunomiae as a pathogen in liver abscess in Korea. Methods: Medical records of 167 patients treated for pyogenic liver abscess from January, 1992 through June, 1999 were reviewed retrospectively in detail. Major Pathogenic organism, clinical manifestations, prognostic factors, the importance of diabetes mellilus as an underlying disease and its effect on clinical features and prognosis were analyzed. Results: Among 167 cases of pyogenic liver abscess, underlying diabetes mellitus was present in 32.3%. The mean age of patients was 62.7 13.4 years in diabetic liver abscess group and 55.1 15.5 years in non-diabetic liver abscess group. Most liver abscesses were cryptogenic in origin or secondary to the billary tree diseases. The clinical presentations among the two groups were not significantly different. When compared to patients without diabetes, patients with diabetes had significantly higher proportions of hypoalbuminemia and elevated aspartate transaminase level. The most common organism of the pyogenic abscess was K. pneumoniae in both groups. Percutaneous drainage of the abscess with appropriate antibiotics was the most commonly used therapeutic modality in liver abscess. The mortality rate of diabetic liver abscess is 16.1 % and 7.1% in nondiabetic liver abscess. Complications, especially septicemla, were found more frequently in patients with diabetes than in patients without diabetes (64.8% vs 28.3%, septicemia : 31.5% vs 9.7%). The factors influencing mortality in the diabetic liver abscess were disease duration, mixed infection, presence of septicemia, elevated bilirubin and alkaline phosphatase. Conclusions: In contrast to prior report that the E. coli was the most common pathogen in liver abscess, we found that K. pneumoniae was the most common organism cultured in liver abscess. Diabetic patients have more complications and higher mortality than patients without diabetes. Early detection and proper treatment are needed to improve the outcome for diabetic patient with liver abscess.

이동로봇의 실시간 장애물인식에 관한 연구

오세봉,Nguyen Huu Cong,김준홍,조창제,한성현 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

This paper achieves a research about avoidance of obstacles avoidance based on ultrasonic sensor. The performance of the proposed obstacle avoidance robot controller in order to determine the exact dynamic systems modeling system that uncertainty is difficult for nomadic controlled robot direction angle by ultrasonic sensors throughout controlled performance tests. In additionally, this study is an in different ways than the self-driving simulator in the development of ultrasonic sensors and unmanned remote control techniques used by the self-driving robot controlled driving through an unmanned remote controlled unmanned realize the performance of factory automation.

활성노드를 가진 자기구성 네트워크에 의한 비선형 시스템의 동정

오성권,박병준,김동원 圓光大學校大學院 2000 論文集 Vol.24 No.-

본 논문은 복잡한 비선형 시스템의 모델동정을 위하여 자기구성 네트워크(Self-organizing Networks; SON)구조의 최적 설계절차에 관련된 새로운 방법론을 제안한다. 제안된 SON 알고리즘은 GMDH (Group Method of Data Handling)방법에 기초를 두고 있으며, 그 구조는 뉴럴네트워크의 구조와 유사하다. 그러나 SON구조는 기존의 뉴럴네트워크 구조에서와 같이 고정되지 않고 새로운 노드를 생성할 수 있다. Son구조의 각 노드는 1차, 2차, 3차 다항식과 같은 여러 가지 형태의 고계 다항식을 사용하고, 여러 종류의 다변수 입력으로 연결되어 있다. 즉, SON은 GMDH에서 사용되는 이차다항식 이외에 확장된 형태의 고계 다항식을 사용한다. 각 세대에서의 노드의 입력수는 다항식에서 사용되는 변수의; 수에 의존한다. 그에 대한 연구는 성능비교를 위해 널리 사용되는 비선형 함수와 수처리 공정을 이용하여 설명되고, 앞선 다른 연구에서보다도 더 높은 정확도를 가진 모델을 생성할 수 있음을 보인다. 그리고 모델의 근사화 및 예측능력에 관련된 성능지수에 의해 평가되고 또한 토의된다. We propose a new methodology which includes the optimal design procedure of Self-organizing Networks(SON) structure for model identification of complex and nonlinear system in this paper. The proposed SON algorithm is based on GMDH(Group Method of Data handling) method and its structure is similar to Neural Networks. But the structure of SON is not fixed unlike in conventional Neural Networks and can be generated its new node. The each node of SON structure uses several types of high-order polynomial such as linear, quadratic, and cubic, and is connected as various kinds of multi-variable inputs. In order words, the SON uses high-order polynomial as extended type besides quadratic polynomial used in GMDH, and the number of input of its node in each layer depends on that of variables used in the polynomial. The design procedure to obtain an optimal model structure utilizing SON algorithm is shown in each stage. The study is illustrated with the aid of Nonlinear Function data besides Waste-water process used widely for performance comparison, and shows that the proposed SON algorithm can produce the model with higher accuracy than previous other works. And performance index related to approximation and prediction capabilities of model is evaluated and also discussed.

建築企劃段階에서 經濟的 妥當性 分析을 위한 기초적 연구 : 建築의 Cost-Benefit Analysis 적용을 중심으로 Focused on Cost-Analysis in Architecture

오승준,전재열 단국대학교 1999 산업기술연구 Vol.1 No.-

C/B analysis technical begins with a balance ; a simple definition induced from the benefit result form construction unit price and rental income. The project is feasible if the estimated benefit exceeds the investment cost. We can see from this thesis that the cost can be redefined as project budget, on the other hand, benefit can be started as an investment value or a present value. Especially architects and developers must be aware that a raise in or a reduction of the budget are not adequate answers for the success of the most effective and rational project modification. In this thesis, I logically try to solve the analysis technique by use of more complicated elements, data, and clarify the relations between cost and benefit. However, I think a profound factor analysis must be followed.