천주 차단 (Tienchu block)을 이용한 후두통치료

정창우,민진혜 關東大學校醫科大學醫科學硏究所 1998 關東醫大學術誌 Vol.2 No.1

The occipital neuralgia starts with dull pain or stiffness of the posterior neck and occipital headache. When advanced, occipital neuralgia, eye general muscle and pain, contraction headache follow. It is frequently seen in pain clinic practice, either as an independent pbenomenon cause by fatigue or as the reffered symptom of other diseases. Tienchu is accupoint B-10 on the bladder meridian. It is situated at the depression adjacent to the upper lateral border of the trapezius muscle. The Tienchu syndrome is a myofasial condition of the posterior neck region with a trigger point. Therefore, a Tienchu block with local anesthetic is a most effective therapeutic method for many patients who complain of posterior headache or posterior neck pain.

Hairless mouse 표피세포의 표면항원 발현에 관한 연구

문태기,이호정,이민걸 關東大學校醫科大學醫科學硏究所 1998 關東醫大學術誌 Vol.2 No.1

It is more convenient to use hairless mouse to carry out dermatological research than to use other mousse with hairs because it has no hair. However, the basic data concerned with the expression of the surface antigens of epidermal cells of hairless mouse are not available until now. In this study, we investigated the expression of some surface antigens including E-cadherin, ICAM-Ⅰ, MHC-Ⅱ, B7-1 B7-2, γδT by flow cytometry analysis. There war no significant difference in expression of epidermal cells between hairless mouse, SKH and other mouses having hairs such as BALB/C, C57BL/6 and C3H/HeN. Slight decrease in E-cadherin expression in hairless mouse, SKH showed the similar surface antigen expression to that of ear. These results suggest that hairless mouse, SKH can substitute mouses having hairs in dermatological research and epidermal cell of trunk as well as ear can be used.

What's progress in the treatment of gastric carcinoma during surgical operation?

Kim, Jin-Young 關東大學校醫科大學醫科學硏究所 1998 關東醫大學術誌 Vol.2 No.1

1701년 Morgagni가 처음 위의 악성병변을 자세히 기술한 후 1881년 Billroth가 위암치료로 유문절제술을, 1897년 Schlatter가 위전절제술을 성공적으로 시행한 이후 여러 가시 변형술식이 위암치료의 주축을 이루어 왔다. 그러다 1941년 Coller등은 많은 예에서 부적절한 위림프절 절제로 인해 전이를 일으킨다고 보고한 이후 림프절 전이에 많은 관심이 이루어졌으며 1981년 일본 위암연구회에서 위암취급규약을 제정하면서 림프절곽청이 활발히 이루어지게 되었다. 그러나 림프절곽청으로 국소 재발을 줄일 수는 있었으나 수술 후 가장 많은 소기재발인 복막전이는 미해결로 남아있으며 1980년 Spratt이 복강내 온열화학적 관류요법을 시행한 이후 1505년 Koga(CHPP), Fujimoto(IPHP) 등의 발표가 이어지게 되면서 최근에는 수술시에도 다양한 재발양상을 예방할 수 복합적인 치료가 필요하다는 의견이 대두되고 있다. 이에 저자는 1988년부터 1992년까지 위암으로 수술 받은 71명의 환자를 대상으로 이를 시기와 방법에 따라 Group Ⅰ은 Standard subtotal gastrectomy 만을 시행한 20예, Group Ⅱ는Lymph node dissection 을 시행한 28예, Group Ⅲ는 Lymph node dissection 과 함께 복강내 온열화학적 관류요법(IHCP)을 시행한 23예 3군으로 분류하여 생존율 및 재발양상을 비교 분석하였다. Group Ⅲ의 경우 저온마취 상태 하에(32.4℃~34.0℃) 위함을 절제한 후 주입관을 좌상복부에 배출관을 골반내 삽입한 후 피부를 봉합하자마자 10 ㎍/ml of mitomycin-C(MMC) 가 포함된 1.5% peritoneal dialysis solution을 44℃ 로 가열한 후 2시간동안 복강내 주입 순환시켰다. 추적기간 중 38예가 재발하였으며 36예가 사망하였다. 총 71예의 3년 및 5년 생존율은 57.8%, 46.7% 있으며 Group Ⅰ과 Group Ⅱ는 50.0%, 46.4%, Group Ⅲ는 87.0%, 49.9%로 유의하게 증가하였다(p=0.007). IHCP를 시행하지 않은Group Ⅰ과 Group Ⅱ의 가장 많은 재발양상은 복막전이로 각각 33.3%(5/15)와 46.7%(7/15)로 나타났으나 Group Ⅲ의 경우는 복강 림프절 전이로부터 침윤된 복막전이1예를 제외하고는 복막전이는 없었으며 상대적으로 국소 전이가 가장 많았다(p=0.001). 결론적으로 위암의 치료는 수술적 절제 뿐 만 아니라 국소 전이를 방지하기 위한 광범위한 림프곽청 및 복막전이를 방지하기 위한 복강내 온열화학요법 등 복합적인 치료기 이루어져야 할 것으로 사료된다.

한국인의 구순 선호경향에 관한 조사

김희석 關東大學校醫科大學醫科學硏究所 1998 關東醫大學術誌 Vol.2 No.1

Study on the beauty sense for face is important for the planning of aesthetic and reconstructive surgery. The purpose of this study is to justify the concept of preferred of disliked lip among the Korean adult female and male. The selected photographs of Korean adult females(21 frontal view and 28 lateral view) were classified lip seven types by measured heights of upper and lower vermilion, and classified as preferred of disliked lip according to the evaluation of 600 adult Korean. The following results were obtained, 1. Most preferred lip of Korean adult female were distinct lip line and standard of upper and lower vermilion height(type 1. standard type) 2. Most disliked lip of Korean adult female were revealed as type 7(upper thick type) by Korean adult male and type 3(both thin type) by Korean adult female. 3. We think it is valuable to take into consideration of this concept of beauty sense for lip when we make a preoperative plan for lip aesthetic and reconstructive surgery.

십이지장에서 발생한 간양 선암종 : 1예보고 a case report

구자홍,임현철,김진영 關東大學校醫科大學醫科學硏究所 1998 關東醫大學術誌 Vol.2 No.1

The hepatoid adenocarcinoma is a rare extrahepatic primary neoplasm showing similar histopathologic features of primary hepatocellular carcinnoma and usually produce a large amount of alpha-fetoprotein hepatic type. There ate several pathologic and radiologic reports of adenocarinoma of stomach, lung, pancreas, gallbladder, bile duct, ampulla of Vater, renal pelvis arid urinary bladder. Authors report a case of biopsy-proven hepatoid adrnocarcinoma of the duodenum.

Sp1-family 전사인자에 의한 사람의 ATP-citrate lyase 유전자 pwomoter의 활성 조절

박상욱,김경섭 關東大學校醫科大學醫科學硏究所 1998 關東醫大學術誌 Vol.2 No.1

스트레스 대처행동에 관한 연구 : 간호학생의 무력감 경험 및 정서적지지와 관련하여

최미경 關東大學校醫科大學醫科學硏究所 1998 關東醫大學術誌 Vol.2 No.1

This study was designed to investigate the content of stress coping behavior and to examine factors, determining stress coping behavior for nursing students(n= 1.19) in relation to socidemographic variable, the experience of powerlessness, emotional support. Data analysis procedure included factor analysis and stepwise multivariate regressions using stress coping behavior as dependent variables. Analysis showed; 1. As a whole, nursing students showed a tendency of lack in positive stress roping behavior. 2. Contents of stress coping behavior showed that high grade student had more tendency to take stress coping behavior positively than 1ow grade students. 3. Multiple regression analysis revealed that the factors such as grade and religion were to be independently and significantly associated with stress coping behavior: Students who were in high grade and had no religion were tend to take stress coping behavior positively. 4. The experience of powerlessness and emotional support did, inspite of stereotype, poorly impact on stress coping behavior. We tan guess the effect of education indirectively from these findings, but longitudinal studies need to consider the direct effect of education. The results also indicate that the respondents should be on encouraged to take stress coping behavior positively.

A case of herpes zoster that has occurred without chicken pox history in normal early childhood

Cho, Moon Kyun,Lee, Hyun Hee 關東大學校醫科大學醫科學硏究所 1998 關東醫大學術誌 Vol.2 No.1

대상 포신은 주로 성인에서 발생되며, 소아에서는 드물게 발생하는 질환이다. 대상포진의 병변은 군집성 발진이 특징적으로 밴드형태의 분포를 보이며 하나 혹은 그이상의 신경절을 침범하는 질환이다. 원인균은 허피스 바이러스군에 속하는 varicella-zoster바이러스(VZV)이다. 발생기전은 수두를 하는 동안 varicella-virus가 피하신경에 들어가 있다가 varicella-virus가 재활성화 되어 발생된다고 하나 그 이유 아직까지 명확하게 알려지지 않지 있다. 재활성화 시키는 요소는 피로, 연령, 면역 억제제, 림프종, 백혈병 등이 관계된다. 소아기에서 대상포진을 면역상태가 좋지 않은 소아, 자궁내 감염이 있었던 경우, 생후 수두를 앓은 경우 발생한다. 정상 소아의 경우 유아기에 후천적으로 varicella-zoster-virus에 감염되면 대상포진의 발생시기가 단축되며, 된 환아의 경우도 후천적으로 수두백신을 생후 13개월에 접종하였고 그후 13 개월 후 발생된 것으로 보인다. 저자들은 수두의 병력 없이 백신접종 후 발생된 것으로 보이는 대상포진을 경험하였기에 보고하는 바이다.

자궁내말암종에서 표피성장인자 수용체의 발현과 DNA량 분석소견

이상엽 關東大學校醫科大學醫科學硏究所 1998 關東醫大學術誌 Vol.2 No.1

In endometrial carcinomas, one of the most difficult problems in clinical management has been to identify women with low stage disease who have a substantially increased risk of developing recurrence. Numerous studies to find the prognostic indicator of endometrial carcinomas were performed, but little is known about the relationship between the overexpression of epidermal growth factor receptor(EGFR) and findings of flow cytometric DNA analysis. The immunohistochemical reactivity of antibodies against EGFR and flow cyromertic DNA analysis were examined in 19 endometrial carcinomas, and these finding were compared with histopathological findings and each other. Thirteen of 19 cases were immunohistochemical positive for EGFR(68%). The overexpression of EGFR did not correlate with histological grade, muscle invasion, DNA ploidy, DNA index, S-phase fraction, proliferative index. The cases of high DNA index(1.89 and 1.95) were histological grade 2 and 3 with deep muscle invasion. In this study, the overexpression of EGFR in endometrial carcinomas failed to show correlation with histopathologial findings and results of flow cytometric DNA analysis. But the high content of DNA is related to high histologic grade and deep muscle invasion, therefore it may present important prognostic information especially to patient with low clinical stage.

심한 무지 외반증의 제1 중족지간 관절고정술

최경진 關東大學校醫科大學醫科學硏究所 1998 關東醫大學術誌 Vol.2 No.1

We reviewed the result of the arthodesis of the first metatarsophalangeal joint severe hallux valgus patients. From Feb. 1994 to March 1997, 34 patients were operated on. There were 29 women and 5 men. Their age ranged from 45 to 72 years. The follow-up averaged 21 months. The arthrodesis of the first metatarsophalangeal joint resulted in a significant long-term improvement with respect to pain, the ability to stand and walking shoe wear. Before surgery, the average hallux valgus angle was 43.5˚. The postoperatively hallux calgus fusion angle was an average 8.7˚. Before surgery, the average intermetatarsal angle was 21.5˚. The postoperatively intermetatarsal angle was an average 6.7˚. After surgery, an average dorsiflexion angle was 12.2˚. The arthtodesis of the first metatarsophalangeal joint was a very effective treatment on severe hallux valgus.