식품 기준·규격의 합리적 관리 ·운영에 관한 연구(Ⅰ) : 두부,식용유지, 전분의 분말상 원료에 관하여 Powdered marerials of Tofu, Edible oil, Starch

김희연,홍진환,박혜경,한상배,박종석,이은주,이정성,송경희,최은희,최영준,소경아,성영제,이주엽 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

본 연구는 분말상 원료(전분, 대두분)의 저장유통시 품질변화를 건전성과 안전성 측면에서 검토하여 식품의 기준 ·규격 설정f.」 합지적으로 반영하고자 하였다. 전분과 패두분의 이물을 검사하고, 2종 대두분(중국산, 미국산)을 ?0일간 IS'c와 30t에 저장하면서 성상, 수분, 산가, 과산화물가, 지방산 조성,아플라톡신 BB의 생성여부를 분석하였다. 중국산 대두분 30'』 저장군에서 50일 이후 곰팡이가 발생한 것 이외에 모든 시료에서 양호한 성상을 나타내었고, 전분과 대두닥 모든 시료에서 이물은 검출되지 않았다. 산가는 중국산과 미국산 시료간에 편차를 보여 증국산 30"C, 50일 저장시료에서 약 10배끙도 증가하였고, 과산화물가는 저장 90일후 15'E 저장군은 약 2.3배, 30'c 저장군은 3배정도 증가하였다. 대두분의 주요 지방산은 linoleic acidf18. 2), oleic acid(18 : 1), palmitic acid(16 : 0)이었으며, 3개월 저장에 따른 지방산 함량의 변화는 미미하였다. 아플라톡신 B₁은 모든 시료에서 검출되지 않았다. The objective of this study was to investigate auality changes of type raw materials(starch, soy flour) during various storage conditions. Starchflour(source of China, U.S.A) were slfred under two temperature(15'C, 30'c) forSensory evaluation, (o.reign material test, moisture content, acid value, peroxide ualue,composition, aflatorin Bi were analyzed. China soy flour(stor·ed 30'f) was contaminated by fungj on 50 days. Except for soy flour contardnated by fungi, sensory characteristics were not changed and foreign mater;als were notdetected. Acid value of China soy flour(stored at 30'C, 90 days) was about 10 times higherlevel before storage and acid value was more influenced by source(China, USA). Peroxide valuewas in proportion with the storage period slightly. The major fatty acid of soy flour waslinoleic acid(18 . 2), an(3 the change of fatty acid composition was not observed. Aflatoxlrl Blwas not detected.

Algal bioassay 에 의한 조류생장 제한영양염류 결정

오희목(Hee Mock Oh),이석준(Seog June Lee),김성빈(Seong Bin Kim),박미경(Mi Kyung Park),윤병대(Byung Dae Yoon),김도한(Do Han Kim) 한국하천호수학회 1998 생태와 환경 Vol.31 No.2

Determination of Limiting Nutrient for Algal Growth by Algal Bioassay. Oh, Hee-Mock, Seog June Lee, Seong-Bin Kim, Mi- Kyung Park, Byung-Dae Yoon and Do-Han Kim (Environmental Microbiology Research Unit, Korea Research Institute of Bioscience and Biotechnology, Taejon 305-333, Korea and Water Resources Research Institute, Korea Water Resources Corporation, Taejon 305-390, Korea) Water quaiity and algal growth potential (AGP) using Microcystis aeruginosa were investigated from April to September 1997 in Daechung Reservoir. Secchi disk transparency was 1.1 m in August. Chlorophyll-a concentrations were higher than 10㎍/l at all samples. Total phosphorus concentration was in a range of 0.020∼0.027mg/l which is at the approximate value of 0.03 mg/l, the general critical level of eutrophication. These results indicate that Daechung Reservoir is in an eutrophic state except some temporary times and restricted sites. Phosphorus uptake rate of M. aeruginosa was higher in the water from the epilimnion than in the hypolimnion and also higher under light condition than under dark condition. Therefore, phosphorus uptake rate appears to depend on cellular phosphorous content and light condition, a meaning of endergonic process. Phosphorus was the most frequently limiting nutrient: phosphorus was limiting algal gowth in April and May, nitrogen, phosphorus and trace elements were the limiting factors for algae in August, and trace elements in September. If a fast growing alga, M, aeruginosa, is used as a test organism for assaying AGP, in vivo fluorescence instead of dry weight can be measured for algal biomass and incubation period can be reduced from traditional 14 days to 7 days.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

안전관리를 위한 전력선반송 FSK통신시스템

한경희,이영철 慶南大學校 附設 工業技術硏究所 1993 硏究論文集 Vol.11 No.-

본 논문에서는 전력선을 통신선로로서 이용한 전력선 통신(PLC)시스템의 임피던스, 잡음, 및 동작특성에 대하여 고찰하였으며 PLC시스템으로써 FSK통신 방식을 설계하여 데이터전송에 대한 실험을 수행 하였다. 그 결과 50m까지 신호전송이 가능함을 확인 하였으며, 이 방식을 집단주택 안전시스템에 적용 할 수 있음을 알았다. In this paper, we studied the impedance of power line and noise, operation characteristics of many electric p개ducts for PLC as a communication line. And FSK communication system of PLC media for the data transmission are designed and experimented. As a result, we conform that our transceiver system can communicate within 50m in local Area. And we conforms it can apply for security monitoring system of apartment.

주5일 근무제가 관광ㆍ호텔업계에 미치는 영향에 관한 연구

한경희 한국관광정보학회 2002 觀光情報硏究 Vol.- No.12

The Korean government is planning to gradually introduce the 50day work week in 2002 in order to improve the quality of life of Koreans. At 47.9 hours a week, the average working hours of a South Korean have been much higher than those in many countries, including 44.6 hours in Taiwan, 37.4 hours in the United States and 26.3 hours in Japan. We are now facing the enormous challenge of establishing a now order throughout all sectors in our economy, society, and culture. Shorter working hours can become an opportunity to enhance the quality of life the people and industrial competitiveness. The Expected effects in the tourism sector will be an increase of travel demand during the weekend and changes in travel patterns. some tourism policies are suggested to deal with the changes in the tourism sector. These include an expansion of tourism facilities, enhancement of tourism information, support for low income earners and human resource development for changes which will occur in travel tastes. The 5-day work week system consequently would affect the continuous growth of tourism industry. In order to make the new system improve the quality of people, we should take the initiative in this matter.

단일 기관에서 경험한 소아청소년기 Kikuchi-Fujimoto병의 임상적 고찰

강희원,김한울,이소영,유경하,김혜순,유은선,최희정,김경효 이화여자대학교 의과학연구소 2018 EMJ (Ewha medical journal) Vol.41 No.4

Objectives: Kikuchi-Fujimoto disease (KFD) is characterized by lymphadenopathy and fever, and is usually self-limited. This study analyzed the clinical characteristics of pediatric patients with KFD. Methods: This retrospective, observational, single-center study was conducted in South Korea from March 2008 to October 2015. KFD was diagnosed based on clinical, radiological or histological findings and excluded when there were any other causes of lymphadenopathy. Medical records were reviewed for clinical and laboratory manifestations. Results: A total of 35 cases were included. The mean patient age was 12.1±2.9 years (range, 5 to 17 years); the male-to-female ratio was 1:0.8. The main clinical manifestations were cervical lymphadenopathy and fever in 34 cases (97%). The mean duration of fever was 12.2±8.3 days (range, 2 to 37 days). We noted enlargement of lymph nodes in the cervical, mesenteric (n=5, 14%), axillary (n=2, 6%), and inguinal (n=1, 3%) regions. Hepatosplenomegaly, loss of appetite, and rash were observed. On laboratory examinations, elevation of ferritin, leukopenia, and positivity for anti-nuclear antibodies were frequently observed. Twelve patients underwent biopsy and 23 cases were diagnosed by radiological findings. The mean duration of hospitalization for all cases was 7.9±2.9 days (range, 3 to 13 days) and steroids were administered in 10 cases. KFD recurrence was observed in 2 cases (5.7%) with the time to relapse of 7 months and 4 years. There were no cases with systemic lupus erythematous or other autoimmune disease. Conclusion: KFD should be considered in pediatric patients with lymphadenopathy and prolonged fever. Patients with KFD should be monitored for recurrence and the development of autoimmune disease.

하루 콩단백질 25g 섭취를 위한 메뉴작성 및 영양성분 분석

한재숙,김정애,서봉순,이연정,서향순,조연숙,한경필,이신정,오옥희,우경자,조은자,구성자,김수진,李承彦,南出隆久 동아시아식생활학회 2002 동아시아식생활학회지 Vol.12 No.2

The purpose of this study was to develop menus for daily intake of 25g soybean protein and to analyse nutrients of these foods. Analytical values were compared to the theoretical one using the food composition table and recommended dietary allowances for Koreans (7th revision). The results are as follows. 1. Soybean curd residue stew, Soybean curd, Kimchi saute, and hard boiled soybean and lotus root were selected for the menu for January, of which the content of soy bean protein(SBP) was 33.1g, soybean stew, soybean curd and soybean sprout saute, and Italian deep fried soybean curd were for February, of which the content of SBP was 35.0g. The content of SBP in soybean paste soup with soybean curd, fried soybean curd and fried soybean curd roll, the menu for March, was 24.9g. That of April were soybean curd gratin with soymilk, soybean curd and ham with garlic dressing and the content of SBP was 26.3g. That of May were soybean porridge, soybean flour cake with honey (Dasik), soybean sprout soup and the content of SBP was 26.7g. That of June were soymilk, pan-fried soybean curd, steamed soybean curd with chicken and the content of SBP was 28.4g. That of July were noodle with soymilk, mapatofu, soybean curd salad and the content of SBP was 24.7g. That of August were soybean sprout with mustard dressing, Tossed green pepper with raw soybean flour, Tofu and Kimchi stew, soybean curd steak and the content of SBP was 26.2g. That of September were Chinese cabbage soup with raw soybean flour, sweet and sour tofu and the content of SBP was 23.2g. That of Oct. were Fermented soybean stew, soybean pan cake and the content of SBP was 24.3g. That of November were not-pressed soybean curd casserole, pan-fried mashed soybean curd with egg, stir frying deep-fried soybean curd with vegetables and the content of SBP was 22.4g. That of December were soybean curd and mushroom casserole, fried soybean curd and vegetables, hard boiled soybean curd and the content of SBP was 28.9g. 2. The ratio of the analytical value over theoretical value (A/B%) of one serving in kcal, carbohydrate, protein, fat, ash and dietary fiber were 57.7~107.7%, 42.9~131.9%, 79.2~118.3%, 54.5~100%, 40.7~80.8% and 42.1~113.2%, respectively. 3. The ratio of A/B% of one serving in Ca, K, Na, P and Fe were 44.1~93.6%, 59.0~153.1%, 53.1~117.7% 64.6%~138.8 and 33.8~77.3%, respectively. That in Fe was the lowest among minerals. 4. The ratio of analytical value over Korean R.D.A(A/C%) in Ca was relatively higher (22.0~85.9%) than that in kcal(18~63%). 5. The ratio of A/C% in Fe was 25.1~64.3% and lower than that in Ca and protein in general.

창녕 교동 제89호분 출토 금동제 안교장식 : 보존처리와 제작기법 조사

김경희,한만성,안병찬 국립중앙박물관 1999 박물관보존과학 Vol.1 No.-

국립김해박물관 개관전시를 위해 일제시대 창녕 교동 제89호분에서 출토된 금동제안교장식(金銅製鞍橋裝飾 이하 “안교장식”)을 보존처리하였다. 안교장식은 수많은 편으로 파손된 채 다른 유물과 뒤섞여 보관되어 왔다. 보존처리는 유물의 원형을 되찾고 재질을 안정화시키는 점에 두고 과학적인 조사와 처리를 실행하는 한편 유물의 제작기법도 상세히 조사할 수 있었다. 그 결과 안교장식의 두꺼운 부식생성물을 벗기고 파편을 접착하여 원래 모습으로 복원하게 되었고 전시와 관리도 가능하게 조치하였다. 또한 다양한 고대 제작기법이 적용된 안교장식임을 확인할 수 있었다. Conservation treatments were done for the gilt bronze saddle accessory excavated from Tomb No. 89 in Kyo-dong, Changnyong in Japanese rule period. The saddle accessory, broken into numerous pieces, was mixed with other remains. Principal aims of conservation treatments were to recover original shape of object and stabilize its material. In the process of treatments manufacturing technique of the remain was examined minutely. Thick layers of corrosion substances were peeled off and numerous pieces were pasted together to restore the original shape. And then the saddle accessory was mounted on an acrylic board to be handled and exhibited safely. In this process, it was confirmed that various ancient techniques of metalic crafts such as amalgam gilding, riveting, piercing, line engraving, stamping, chasing etc. had been used to make the saddle accessory.

움직임 추정과 웨이블릿 변환을 적용한 비디오 디코더용 3D 적응 comb 필터링에 관한 연구

한희철,김진상,조원경,김남섭 경희-다반 ASIC 설계교육센터 2002 경희-다반 ASIC센터 논문집 Vol.3 No.-

NTSC 비디오 신호에서 comb 필터링은 라인과 프레임 사이의 위상차를 이용하여 Y와 C를 분리하는 기술이다. comb 필터링의 가장 중요한 부분은 기준 라인을 가지고 가장 높은 상관관계를 가지는 라인을 찾는 것이다. 본 논문에서는 프레임 안에 라인 사이의 유사성을 계산하기 위해 움직임 추정과 웨이블릿 변환을 적용한 새로운3D Y/C 분리 방법을 제안한다 제안한 알고리즘을 comb 필터링에 적용하였을 때, 화질은 기존의 시간 영역의 3D comb 필터링보다 약 1~2dB 향상되었다. 차후 연구 과제로 NTSC 비디오 신호의 유사성 검출에 효율적인 웨이블릿을 찾는 것과 잡음에 대한 내성을 강화해야 하며 최종적으로 하드웨어로 구현하는 것이다.

관학연계 주간보호센터 사업 운영 프로그램 개발 : 동작구민을 대상으로

한승의,김경희,정연강,전인희 중앙대학교 간호과학연구소 2001 중앙간호논문집 Vol.5 No.2

The purpose of this study was to sere as a basis for the development of more successful programs for the elderly who used adult day care center, by examining the Activities of Daily Living, Instrumental Activities of Daily Living and dementia symptom of elderly people who wed in Dongjak-gu in Seoul. Data for this present study were collected from 260 people via questionnares randomly distributed to over 65-year-old elderly people who lived in Dongjak-gu in Seoul from March to June, 2001. The findings of this study were as below: 1. For general characteristics, the women outnumbered the men, as the former group accounted for 63.8% of the subjects and 36.2% were male. By age, the largest age group was 71 to 75, which accounted for 43.2%. By disease, 87.3% suffered from disease, and most of them had mode than one disease. 2. For Activities of Daily Living, washing and dressing mean scored the highest with 2.96, and bathing stored the least with 2.87. 3. Concerning Instrumental Activities of Daily Living, what's in want of the greatest help was going shopping(4.5%), followed by cooking(4.5%) and laundering(4.5%) in the order named. 4. As a result of making a primary dementia screening test, 68 people(26.2%) were suspected to have dementia, and those people need to take dementia diagnosis test to fond out dementia prevalence.