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신태용,염정열,김원,김현미,박해정,장진이,조성룡,채병숙 우석대학교 생명과학연구소 1998 생명과학연구소 논문집 Vol.2 No.-
We investigated the effect of aqueous extract of Ammomum xanthioides(AXAE) on immediate hypersensitivity. AXAE inhibited systemic anaphylaxis induced by compound 48/80 in mice. AXAE inhibited serum histamine levels induced by compound 48/80 in mice. Moreover, AXAE dose-dependently inhibited histamine release in peritoneal mast cells activated by compound 48/80. These results indicate that the AXAE may be benificial in the regulation of immediate type allergic reaction.
1987학년도 부산대학교 신입생의 실태에 관한 조사연구
李成海,辛碩基 釜山大學校 學生生活硏究所 1987 硏究報 Vol.23 No.1
The purpose of this study is firstly to analyze the status and attitudes of freshmen class of 1987 and secondly through this aratlsis to make a plan that helps improve freshmen's adjustment to university life. The main information analyzed in this study was collected by a questionnaire. Informations asked are as follows . (1) backgrounds of each froshman and his/her family, (2) freshmen's attitudes and expectations toward the university and the major field of study, (3) freshmen's attitudes toward the Korean society. (4) some problems facing freshmen and choice of areas of occupational career. The findings and suggestions of this study are summarized as follow: 1. In the same nhanner of other years the economic problems are the most important concern of freshmen. Most of freshmen are hard up for school expense and want to earn their school expense. Therefore, establishment of improved and expanded scholarship and an additional post management is required. 2. Most of freshmen expect a culture, a dilettante life, a building up their character and the formation of wide personal relation. Specially most of freshmen want to professors' humanistic guidance. 3. Most of freshmen want to participate in student circle activity. Therefore the school authorities need to furnish informations that help freshmen's circle selection, and need to produce atmosphere for freshmen's circle activity. 4. Most of freshmen select a field of study without any informations about that subject of study. Also most of freshmeil did not select their major field of study according to their interests or aptitudes, but they chose their field of study by considering possibility of success in admission competition. 5. About 50% of freshmen regard a university as a preparatory stage of occupational career. Therefore it is necessary for freshrrlen to have knowledge of a function of university. 6. Freshmen's attitude toward Korean society was optimistic, but some of them pointed out the corruption of the society and the problems of economy and domestic politics. Also most of freshmen point out that Pusan is somewhat backward in modern culture compared to that of Seoul.
박상호,온영근,김현정,이태훈,길효욱,김현건,박수진,송해정,한대희,방덕원,신원용,이내희,김성구,권영주 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1
Background : Microvascular angina or syndrom X is heterogenous and encompasses different pathogenetic entities. Several studies suggest that microvascular angina have good prognosis and occurs predominantly in postmenopausal women. Lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and fibrinogen are the independent risk factor of acute coronary syndrome and are the chief underlying cause of atherosclerosis. We investigated clinical characteristics and markers in patients with microvascular angina. Methods : We studies 23 patients diagnosed with microvascular angina and 16 control group with negative treadmill exercise test and no significant coronary angiogram. We investigated clinical characteristics in patients group and evaluated symptom during a follow-up period of 4.2± 2.5 month. Exercise time in treadmill exercise test was compared between patients and control group. We assessed the level of markers, such as lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and ESR in two groups. Results : There is no difference in age between two groups. Patients group had a tendency to increase in female, hypertension, DM, and smoking history, but there was no statistical significance difference. Exercise duration time was significantly decreased in patients with microvascular angina (p<0,05). Serum lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholestrol, Triglyceride, ESR, Fibrinogen and Homocystein value were no significant difference between microvascular angina and control group. Only CRP was significantly high in patients with microvascular angina (p<0.05). Conclusion : There was no statistical significance difference in age, sex, hypertension, DM and smoking history between two groups but patients group had a tendency to increase the prevalence in hypertension, DM and smoking history, female. Also, Symptom improvement and disappearance in follow-up was presented in 11 patients of 19(57.9%). Exercise tolerance was worse in patients group than control group. CRP value was significantly higher in patients group than control group. There was no statistical significance difference in lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, ESR and Fibrinogen between two groups.
Comet assay를 이용한 Ferric Sulfate의 유전자 독성에 대한 연구
박혜련,정태성,김신,강호승 大韓小兒齒科學會 2000 大韓小兒齒科學會誌 Vol.27 No.1
치수절단술은 유치의 치수치료 방법 중 사용빈도가 높은 시술 중 하나로 치수절단 술식에 사용되는 약제는 치수나 주위조직에 무해하여야 하며, 감염이나 내흡수 등의 부작용이 없어야 한다. 본 연구는 임상에서 유치의 지혈적 치수절단 술식의 약제로 사용되는 ferric sulfate의 유전자 독성을 평가할 목적으로 human gingival fibroblast에 ferric sulfate를 다양한 농도와 접촉시간을 설정한 후 comet assay를 이용하여 유전자 독성을 평가하여 보았다. 그 결과는 다음과 같다. 1. 농도에 따른 세포의 유전자 손상정도의 변화는 ferric sulfate의 농도에 비례하여 유전자 손상이 증가하는 양상을 나타내었다. 2. 농도에 따른 세포의 유전자 손상정도는 0.1,mM이상의 농도에서 대조군과 유의한 차이를 나타내었다.(p<0.05) 3. 시간경과에 따른 세포의 유전자 독성의 변화는 대조군과 유의한 차이를 보이지 않았다(P>0.05). Although ferric sulfate has been proposed as an alternative to formocresol in pulpotmy treatment in primary teeth, it has been given little concern regarding its cytotoxicity and mutagenicity. In the present study, we assessed the in vitro genotoxic effect of a ferric sulfate on human gingival fibroblast cell line (HGF-1), DNA damage was evaluated using comet assay (single cell alkaline gel electrophoresis) and obtained the results as follows: 1. A dose-response relationship was found between ferric sulfate concentrations (0 to 5mM)and DNA damages. 2. Above the concentration of 0.1mM, DNA damage was significantly increased than those of the control (p<0.05). 3. At the fixed concentration of 0.05mM, no significant difference was found between exposure time and DNA damage. These findings suggest that ferric sulfate as a pulpotomy agent can induce DNA damage in human gingival fibroblasts.
CT flouroscopy를 이용한 중재적 시술의 유용성
전혜정,박정희,서보경,박상우,신현준,최영철,한혜승,이창희 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-
Conventional CT-guided needle localization has been reported many times, but a few reports of interventional procedures by using multidetector CT scan with CT-fluoroscopy have been described. We presented 36 cases of CT-fluoroscopy guided interventional procedures focusing on the puncture technique. Two cases of small pneumothorax and one case of pulmonary hemorrhage out of 2lcases after lung biopsy, were not needed any treatments We can easily and accurately access to the lesion by using CT-fluoroscopy and unique our marker system.
근저항 트레이닝이 20대 여성의 신체조성과 체력에 미치는 영향
이상우,김봉환,서해근,강신범,나재철 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1
The purpose of this study was to investigate the effect of muscular resistance training on the body composition and the physical fitness. The subjects of study were 6 women in their twenties who had not taken will in ordinary days and had not gone through regular training. The above subjects were measured by body composition and physical fitness pre and post 8 weeks training. The frequence training was more than 4 times a week and the duration of training of each session was 70 miniutes. The results are as fallows: 1. In muscular resistance training for 8 weeks, % Fat 1.8%(7.76%), and Fat weigh 3.0kg(23.43%), wee decreased, while LBM 3.0kg(7.10%) was increased, However, there was no differences. 2. In muscular resistance training for 8 weeks, it was exposed to be increased a little in Left arm strength 2.65kg(9.60%), Fight arm strength 2.03kg(7.78%), Left leg extention strength 12.47kg(6.16%), Right leg extention strength 4.50kg(2.35%), Left leg flextion strength 13.67kg(13.01%), Right leg flextion strength 13.25kg(12.70%), Standing trunk flextion 3.25㎝(18.16%), Front split 2.67㎝(1.65%), Side step 3.83friq(11.16%), Vital capacity 5.02cc(0.22%).