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      • 반월, 시화공단 악취물질의 안산지역 확산 연구

        송동웅,송창근,김영노 漢陽大學校 環境科學硏究所 2003 環境科學論文集 Vol.24 No.-

        안산지역은 인근 반월, 시화공단에서 발생하는 악취 및 부유물질로 인한 민원이 그치지 않고 있으며 그 동안 지속적인 악취저감대책에도 불구하고 근원적 해결이 안 되고 있다. 특히, 안산지역은 구지풍인 해륙풍의 영향을 강하게 받는 연안도시로 해풍의 유입과 관련한 오염물질의 이동과 확산과정을 시뮬레이션함으로써 악취민원 발생지역의 범위 예측과 고농도 발생일의 원인규명들을 위한 과학적이고도 정확한 분석이 필요하다. 따라서 본 연구에서는 반월, 시화공단에서 배출되는 악취물질이 해륙풍등의 국지순환에 의하여 이동, 확산되는 과정을 규명하기 위해 대기확산모델링을 실시하였으며 모니터링자료를 이용하여 모델의 재현성을 평가하였다. There have been persistent civil appeals in Ansan area against the odor and aerosols emitted from nearby Banwol/Sinhwa industrial complex. A fundamental solution for the good air quality has not been addressed yet in spite of the continuous counterplan to reduce odor emission. A systematic and scientific study is needed to examine the reason for the odor episode and to predict the impact coverage of odor pollution. An approach by computational simulation is considered to be adequate to investigate the transportation and the dispersion processes of air pollutants blown by sea breeze toward the coastal city, Ansan. This study has employed various dispersion models to simulate the transportation and the dispersion processes of odor pollutants by a local circulation between land/sea breeze using the data set of emission rates of odorous species from the Banwol/Sihwa industrial complex.

      • 붓스트랩을 이용한 EWMA관리도의 수행도 평가

        송학진,박영호,이만웅 동의공업대학 2001 論文集 Vol.27 No.1

        In this study, we establish bootstrap control limits for EWMA chart by applying the bootstrap method, called resampling, which could not demand assumptions about pre-distribution when the process is skewed and/or the normality assumption is doubt. The results obtained in this study are summarized as follows : bootstrap EWMA control chart is developed for applying bootstrap method to EWMA chart, which is more sensitive to small shifts of process. With the purpose of eliminating a skewness of the resampling distribution, the bootstrap control limits are established by using a modified residual, and its performance is analyzed by ARL. It is shown that the bootstrap EWMA control chart developed in this study includes the properties of standard EWMA control chart that is sensitive to a small shift, and detects process in out of control more quickly than standard EWMA chart.

      • 비용ㆍ일정 통합관리를 이용한 커튼월 자재관리

        송영웅,최윤기 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

        The systematic material management of curtain wall should be established on accomplished EVM data. The matrix method of integrated cost and schedule was used with common category concept according to the construction project control system. The material management was suggested through analyzing curtain wall process and data model using integrated cost, schedule and material. In this study, the material management of curtain wall based on historical data to the related EVM is proposed. This Material management of curtain wall model can provide a standard process and data which are related to the integrated cost, schedule data.

      • 백서의 복강내에 투여한 Mitomycin-C-Polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

        송규상,강대영,최정목,노승무,정경수,오정연,김진향,양준목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

        To evaluate the in-vivo effects of mitomycin-C-polyglycolic acid composite(MMC-PGA) the disk: shaped composite were implanted into the peritoneal cavity of the Sprague-Dawley rats. The pathologic changes were examined at various time points up to 12 weeks. Initially the soft tissue around the inserted disks showed capillary congestion at 3 days. Inflammatory infiltrates with foreign body giant cells appeared from the 2nd week and reached peak response at 6-8 weeks. These reaction diminished prominently at 12 weeks. No specific pathologic change was found in the liver, the kidneys, and the heart. The above results suggest that the MMC-PGA composite can serve as a new device for intraperitoneal chemotherapy of various types of cancers.

      • 洞報 廢鑛山 周邊地域 土壤 內 重金屬 移動 分布

        문영옥,정송송이,최상민,김민철,박창웅,오광중 부산대학교 환경문제연구소 2003 環境硏究報 Vol.21 No.-

        In this paper, we study heavy metal transport and distribution of soils around Dong-bo abandoned mine area. Inside the mine, concentration of Cd, Ca, Zn are exceeded soil management standards. Outside of mine, concentration of Pb, as is exceeded soil management standards. Especially, concentration of Pb is higher than soil protection standard of 300㎎/㎏ in S-6 point which is tailing accumulation area. Although heavy metal concentration of mine water was higher than Unsuchon, water contaminated level was lower than soil. 30cm-depth soil is serious in S-6 point, heavy metal transport had influence on Unsuchon. Further more, we used pollution index(PI) to evaluate soil contamination totally, it exceeded standard "1" in S-6 points of surface soil and 30cm-depth soil. So it decided that contamination of heavy metal is more seriously than other sampling points. In contaminated soil, pH and organic contents are lower than non-contaminated soil. Therefore heavy metal concentration has influence on adsorption and retardation of soil by pH and organic contents variation. Moisture contents also encouraged heavy metal transport velocity, but less than pH and organic contents.

      • 共沈法에 의한 Ferroxplana (Ba₂Zn₂Fe O)의 合成과 磁氣特性

        吳英佑,宋泰雄 慶南大學校 附設 工業技術硏究所 1986 硏究論文集 Vol.4 No.-

        GHz대 통신에 사용되는 Ferroxplana (Ba₂Zn₂Fe??O??)를 제조하기 위하여 최적의 공침 조건과 건조 조건을 새로 고안한 기구를 사용하여 공침합성하였다. 이 방법으로 제조한 시료는 미세한 분말이었으며, 소결시편의 조성과 미구조는 X.R.D, DAT 및 현미경으로 조사하였다. 하소시편 내의 Zn₂Y의 활성화 에너지는 약 3.75-4.10×10⁴J/mole이었으며 소결시편에는 Zn₂Y상외 BaM과 Zn₂W상도 발견되었다. 이렇게 제조된 시편은 고주파 통신용 자기 코아로써 적용 가능하였다. In order to precipitate ferroxplana(Ba₂Zn₂Fe??O??), which is useful for GHz-band communication, the optimum co-precipitating and drying condition were investigated by use of a new apparatus. By the freezing-drying, aceton-compulsion drying, hot petroleum drying and calcining the co-precipitated mixtures, the fine and uniform powder was obtained, whose phase composition and microstructure were studied by X.R.D,, DTA and metallurgical microscope. In results, it was found Zn₂Y, BaM and Zn₂W were the representativ phases in calcined specimens and crystal growth activation energy of Zn₂Y was about 3.75-4.10×10⁴J/mole. The sintered specimens would be appreciated as useful magnetic cores for the high frequency communication.

      • 벼 생산경영 종합관리 S/W개발

        김웅,김창수,김동원,국중덕,송영주,오남기,최영근 한국농업정보과학회 2001 농업정보과학 Vol.3 No.1

        This programme consisted of 8 menus, which are basic information, job worksheet, technique information, management analysis, file management, window management, help and conclusion. The major functions of this programme by menus classified as follows : 1. The basic information menu, which consisted of a lots of basic farm management information, can be easily accessible to get general farm status of S/W users and inputted data used as basic data for farm management analysis. 2. In worksheet menu, users can easily access to record and search of farm work planning, contents of work, agricultural materials and selling status. 3. In management achievement menu, lots of indexes which represent one years' management achievements are produced and can be compare this years' achievements with last years' ones. This programme Delphi5 and Object pascal programme were used for tools and languages. Also Paradox4 and BDE were used for DB and DB engine respectively.

      • KCI등재후보

        사람폐암세포주 (PC-14)에서 Cyclosporin A에 의한 Adriamycin 내성의 극복

        김영환,홍원선,송재관,강윤구,이진오,강태웅,김건열,한용철 대한내과학회 1990 대한내과학회지 Vol.38 No.3

        Cyclosporin A and verapamil were tested using MTT assay to evalute the modification effect on the resistance to adriamycin in a human lung cancer cell line(PC-14) and its resistant subline(PC-14/A). PC-14/A was derived by the continuous exposure of PC-14 to incremental concentrations of adriamycin. PC-14/A was 2.5 times more resistant to adriamycin in terms of ICso than PC-14. Cyclosporin A alone, at a concentration of 2.5㎍/㎖, inhibited the growth of PC-14 to 68.3%. 2.5㎍/ ㎖ and 5.0㎍/㎖ of cyclosporin A showed an increase in the cytotoxicity of adriamycin (p<0.01) with 5.0㎍/㎖ being greater than 2.5㎍/㎖(p<0.01). Excluding the direct cytotoxic effect, however, cyclosporin A did not increase in the sensitivity of PC-14 to adriamycin but only showed an additional cytotoxic effect with adriamycin. Verapamil (up to 6.0㎍/㎖) did not inhibit the growth of PC-14. 3.0㎍/㎖ of verapamil did not increase the cytotoxic effect of adriamycin. The combination of cyclosporin A and verapamil with adriamycin enhanced the cytotoxicity of adriamycin, but the result was similar to that of cyclosporin A with adriamycin. 5.0㎍/㎖ of cyclosporin A modified the adriamycin resistance of PC-14/A(SR, 3.2). However, 3.0㎍/㎖ of verapamil did not significantly reverse the adriamycin resistance of PC-14/A. The modified effect of the combination of 5.0㎍/㎖ of cyclosporin A and 3.0㎍/㎖ of verapamil was similar to that of 5.0㎍/㎖ of cyclosporin A alone in PC-14/A. These results demonstrate that cyclosporin A has an additional cytotoxic effect with adriamycin in PC-14 and PC-14/A and has overcome the acquired resistance to adriamycin in PC-14/A. They also suggest that cyclospoin A may have the therapeutic potential in the treatment of human lung cancer.

      • Rat의 복강내에 투여한 5-fluorouracil-polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

        강대영,송규상,최정목,노승무,정경수,오정연,김진향,양준묵,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

        For more effective intraperitoneal chemotherapy, the authers made 5-fluorouracil-polyglycolic acid composite disks(FU-PGA disks) with 5-fluorouracil and polyglycolic acid, a biodegradable polymer. We inserted the FU-PGA disk into the peritoneal cavites of Sprague-Dawley male rats, the control and three experimental groups; one FU-PGA disk insert group(300mg/kg), two FU-PGA disk insert group(600mg/kg), and three FU-PGA disk insert group(900mg/kg). The control group received a similar number of PGA disk inserts. A pharmacokinetic study was performed to measure the 5-fluorouracil concentration in the peritoneal fluid, blood, and tissues(liver, kidney and heart) at 24 hours, 72hours and 168 hours after insertion of the FU-PGA disk. Light and electron microscopic studies were done. The results were as follows: 1) The number of white blood cells and platelets decreased after FU-PGA insertion. The degree was proportional to the duration and amounts inserted. The change in the number of red blood cells varied slightly. 2) Light microscopically, slight changes were noted at 168 hours in the 3 disk insert group (900mg/kg). Mild fatty change and hepatocyte degeneration around the central veins of the liver were noted, with vacuolar degeneration in the proximal convoluted tubules of the kidney. 3) Electron microscopically,the liver showed focal increases of lipid droplets in the hepatocytes, and irregular nuclear membrane with focal nucleolar segregation of the fibrillar and granular elements. Also the double membranous structure of the hepatocytes and Kupffer cells was widened with bleb formation. The kidney showed wide separation of the nuclear double membrane in the proximal convoluted tubular cells and mesangial cells, with vacuolation and myelin figure formation in the mitochondria of the proximal convoluted tubular cells, at 72 hours and 168 hours in the 2 to 3 FU-PGA insert groups. The heart showed focal loss of cristae,vacuolation and myelin figure formation in the mitochondria of the 2 to 3 FU-PGA insert groups. In conclusion, despite the large amont of FU-PGA inserted, the histopathological changes in the liver, kidney and heart were slight, and consonant with the very low amount of 5-fluorouracil concentrations detected in the liver, kidney and heart. The above results suggest that the FU-PGA composite can serve as a new device for releasing drugs in a controlled manner and easily targeted to intraperitoneal organs. This device can improve the efficacy of intraperitoneal chemotherapy for gastric cancer.

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