랫드에서 신우황청심원의 급성 및 아급성독성시험

오승민,남혜윤,김준수,연제덕,신대희,이진영,박대규,조명행,정규혁 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

The acute and subacute toxicity of New Woohwangchungsimwon(NWCH) which was used l-muscone as substitutive material of musk were investigated in S.D. rats. In intraperitoneal acute toxicity test, rats(Sprague-Dawley, SPF) were injected intraperitoneally with dosages of 0, 540, 750, 1,070, 1,500 and 3,000 ㎎/㎏. Body weights were significantly decreased at 540 ㎎/㎏ dose group in both sexes and abnormal autopsy findings were founded in both sexes at all treated groups. Intraperitoneal LD_50 of NWCH was 812.3 ㎎/㎏ in male and 872.3 ㎎/㎏ in female rats. In the subacute toxicity study, NWCH was administrated orally to both sexes of rats for 4 weeks as several doses(0, 320, 800 and 2,000 ㎎/㎏). There were neither dead animals nor significant changes of body weights during the experimental period. In addition, no differences were found between control and treated groups in clinical signs, urinalysis, hematology, serum biochemical analysis, and other findings. Above data strongly suggest that no observed adverse effect level of NWCH might be over 2,000 ㎎/㎏/day in this study.

면접조사를 통한 초등학생의 영양교육 실태 및 실천도 조사

오유진,이영미,김정현,안홍석,김정원,박혜련,서정숙,김경원,권오란,박혜경,이은주,성현이 대한지역사회영양학회 2008 대한지역사회영양학회지 Vol.13 No.4

This study investigated the experience and practice of elementary school students on nutrition education. The data were collected from 217 male and female students attending 5-6th grade elementary schools in Seoul and Kyunggi-Do from March to June 2007, interviewing face to face by a nutrition teacher and 3 interns of a nutrition teacher. The results were as follows: 86.5% of the subjects learned about ‘Table etiquette’, ‘Reasons for eating fruits and vegetables’ (78.7%), ‘Food waste and environment’ (72.3%), ‘Healthy snacks’ (55.7%), ‘Food sanitation’ (52.3%), ‘Food culture of foreign countries’ (48.1%). Nutrition education experience was significantly different by gender. A total of 43.5% boys responded that they never learned about ‘basic food preperation’ (p < 0.01). They had learned ‘Nutrients for body’ and ‘Food waste and environment’ in school, ‘Healthy weight loss’, ‘Food culture of foreign countries’, ‘Food circulation’ on television, Most content (‘Table etiquette’, ‘Simple cooking’, ‘Food sanitati n’, ‘Eating behaviors for health’, ‘Reasons for eating fruits and vegetables’, ‘Healthy snacks’) was learned from parents. The practice after nutrition education was higher in ‘Table etiquette’ (2.14), ‘Eating fruits and vegetables’ (2.07) than others compared with education experience. The most reason of non-practice on nutrition information was ‘Troublesome’. In ‘Nutrients for body’, a boy answered ‘Difficult for practice’ 20.0%, a girl answered ‘Difficult to understand’ 32.6%, showing a significant difference between the gender groups (p < 0.001). They remembered the ‘Nutrients for body’ (49.6%), ‘Food sanitation’ (44.5%) because of ‘important content’,‘Basic food preparation’ (40.6%), ‘Food culture of foreign countries’ (36.3%) because of ‘interesting content’, ‘Healthy weight loss’ (52.0%), ‘Eating behavior for health’ (44.5%) and ‘Healthy snacks’ (33.7%) because of ‘need for my health’.

식품 중의 아크릴아마이드

오상석,김혜영,박재영 이화여자대학교 생활환경대학 인간생활환경연구소 2004 인간생활환경연구소 논집 Vol.- No.2

Swedish National Food Administration reported that acrylamide was detected in heat treated starch rich food products in April.2002. Acrylamide is considered as potential carcinogen and genotoxicant. It is noticed that formation of acrylamide in potato products was greater than other food products. It may be due to high concentration of asparagine and glucose in potato products comparing to that of other food products resulting in Maillard reaction during heat treatment. Research on acrylamide formation during food processing has been hot issue among other research groups. In this study, general issues on acrylamide in food products including risk assessment, mechanism, toxicity, anallfical method and reduction are discussed.

난소 기형종에 동반된 직장후방 기형종

오보영,이령아,구혜수,문혜성 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.2

분노조절 프로그램이 시설아동의 공격성에 미치는 효과

오영현,송영혜 대구대학교 특수교육재활과학연구소 2009 再活科學硏究 Vol.27 No.1

본 연구는 공격성향의 시설아동을 대상으로 분노조절 프로그램을 실시하여 공격성의 변화를 보는 것이다. 연구대상은 K군 소재 청소년의 집에서 생활하는 초등학교 6학년 아동으로 선정방법은 ‘공격성 진단 검사’와 ‘공격욕구검사’로 공격성의 정도가 심한 아동 6명을 선정하여 실험집단과 통제집단에 각각 3명씩 무선배정 하였다. 프로그램은 이완활동, 문제해결훈련을 지도하는 토론, 회기 목표와 관련된 구조화된 활동, 자유놀이 단계로 구성되었다. 프로그램의 참여도를 높이고 최상의 학습 상태를 받아들일 수 있도록 하기 위해 프로그램 초반에 이완활동으로 신체적&#8228;정서적 긴장을 해소하고 즐거움을 주는 신체놀이를 했다. 분노조절을 위해 사회적 기술훈련, 인지-행동적 접근, 자기교시훈련, 자기주장훈련과 문제해결 기술훈련, 긴장이완훈련의 보편적인 방법을 사용하였고, 프로그램의 진행은 한 회기 60분, 주 2회, 총 10회기 실시하였다. 본 연구의 결과는 다음과 같다. 첫째, 분노조절 프로그램은 공격성 검사에서 공격성을 감소시켰고 하위영역의 공격행동(신체적, 언어적, 우회적공격성, 부정성, 흥분성, 적의성)을 모두 감소시켰다. 둘째, 회기 내에서 시설아동의 공격행동(신체적, 언어적, 우회적공격성, 부정성, 흥분성, 적의성)을 감소시켰다. The aim of the study is to examine changes in aggression level of the aggressive children residing in an institution by applying an anger control program. Children residing in an Institution for Minor in K county who were in the sixth grade of the elementary school were subjected to an 'aggression diagnose test' and a 'desire for aggression test.' Total six children with high aggression scales were selected by the test, and three were randomly assigned in a control group and the rest three in a test group. The program was comprised of relaxation activity, discussion to guide problem solving ability, structured activity related to a goal specific to each session, and free play. To encourage an active participation in the program and enable an optimal reception of the learning, a relaxation activity with fun physical play was conducted at the beginning of the program for releasing physical and emotional tension. A universal method was used to control anger including cognition-behavioral approach and training for social skill, self-instruction, self assertion, problem solving skill, and tension release. The program was implemented twice a week for 60 minutes per session for ten weeks in total. The research tasks were as follows: first, to examine whether the anger control program reduces aggression of the children in an institution; second, whether the program reduces physical, verbal, and indirect aggression, denial, rage, or hostility as sub-categories of the aggression; and third, whether the program reduces aggressive behavior of the institutionalized children within a session. Changes of the aggression according to the research tasks were measured and compared before, after, and as a follow up of the program. To measure aggressive behavior such as physical, verbal, indirect aggression, denial, rage, and hostility, frequency of such aggression was recorded in a free play environment. The results of the study are as follows. First, the anger control program reduced the aggression according to the aggression test. It also reduced all aggressive behaviors such as physical, verbal, indirect aggression, denial, rage, and hostility. Second, it reduced aggressive behavior of the institutionalized children within a session such as physical, verbal, indirect aggression, denial, rage, and hostility. Although the study was a case study of a relatively small number of participants with limitations for a generalization, the results of the study showed that the anger control program had a positive effect on reducing the aggression of the children in an institution.

乾癬患者 臨床報告

吳恩英,朴惠宣,池鮮渶,具德謨 동의대학교 한의학연구소 2001 동의ㆍ경산 한의학 학술대회 Vol.5 No.-

A Reports were done on proriasis which were treated by medications of Sasang Constitution and Constitution-Acupunture in Dept. surgery, opthalmology &tolaryngology, college of Oriental Medicine, Kyungsan University, Pohang, Korea, from May 30. 2000 to JUN 30 2001. we gave score and checked involvement, plaque, erythematous popules, invasiveness according to psoriasis area and severity index. The results were as follows: 1. Sasang Constitution classification was Soyanggin 14(93.33%), Taeumgin 1(6.67%) in the 15 cases. Hyungbangsabaeksan is used in 9 cases(60%), Yanggeuksanhoatang is used in 3 cases(13.11%), Geopungchunggisan is used in 3 cases(20%), Hyungbangdojucksan is used in 1 case(6.57%). 2. In the 9 cases, we checked for over 4 weeks, clinical severity of involvement, plaque, total score(psoriasis area and severity index) was siginificantly decreased(p<05). clinical severity of erythematous popules, itching was decreased but lt is not siginificant(p>05). 3. The mean duration of treatmemt was 73.3 days, result of Excellent or Good improvement was showed on over 120 days. These resilts indicate that Sasang Constitution and Constitution-Acupuntuer treatment is effetive on psoriasis and the more study is needed.

외음부에 발생한 혈관근육섬유아세포종 1례

오혜근,구자봉,김동출,심재영,박정훈,박영균,임성철 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

We present a case of angiomyofibroblastoma of the vulva in a 32-year-old woman. The asymptomatic lesion measured 4×3cm and appeared as a gray-white myxoid mass on cut sections Histologically, it appeared as a relatively well-circumscribed spindle cell proliferation with alternating hypercellular and hypocellular areas and proliferation of thin-walled blood vessels. Immunohistochemically, the stromal cells expressed vimentin, CD34 and progesterone receptor, but not desmin, α-smooth muscle actin, S-100 protein and estrogen receptor. These features were similar to those of angiomyofibroblastoma as previously reported in the vulva except negativity for desmin A case of pathologically proven very rare tumor of angiomyofibroblastoma of the vulva is presented with a literature review

기판 단차에 따른 감광제의 분포와 선폭 변화

김진영,오혜근 한양대학교 이학기술연구소 2002 이학기술연구지 Vol.4 No.-

최근 리소그래피 공정은 기판의 거대화와 더욱 작은 최소 선폭의 요구로써 감광제 최적의 두께와 균일도를 얻어야만 한다. 기판 위에 도포되는 감광제의 두께는 기판의 전체 범위에서 대체로 균일하다. 그러나 기판위의 단차에 도포된 감광제의 분포는 단차 주위에서 변화가 발생하며 이 변화는 단차의 크기와 형태에 따라 변한다. 작은 단차가 주기적으로 형성되어 있을 때 그 위에 분포되는 감광제의 절단면은 그 밑의 단차의 형태와 관련되는 방정식으로 정의된다. 우리는 이 논문에서 회전 도포시 강광제 표면을 예측할 수 있는 식을 찾기 위해 lubrication approximation을 적용하여 Navier-Stokes 방정식을 사용하였다. 마지막 감광제의 두께는 용매의 증발과 전열처리를 거치게 되며, 이때 감광제의 분포는 단차의 크기, 형태, 단차의 밀도에 따라 변했다. 우리는 이러한 영향을 지체적으로 개발한 리소그래피 예측 시뮬레이터인 LUV(Lithography for Ultraviolet)을 사용하여 단차 주위의 감광제 분포에 따른 선폭 변화를 통해 알아 보았다. The photoresist coating should be optimized in thickness and uniformity with larger substrate and smaller critical dimension. Resist thickness on a wafer can be roughly uniform, but thickness variation can occur around topology with the formation of a topology on a substrate. With a presence of a topology formed by narrow and periodic patterns, the photoresist thickness profile should be determined by an equation accountable for the underlying topography. To obtain the spun-on resist surface profile around a topographical feature, the equation combining mass continuity and Navier-Stokes equation using the lubrication approximation was used. The resulting thickness is changed with feature size, shape, density, and topology. The final dried resist thickness profile was obtained by applying the resist thickness reduction due to evaporation and soft bake. This non-uniformity in the resist thickness will affect critical dimension of the semiconductor device.

가구와 가전제품의 재활용에 관한 연구

권오정,김시월,이혜임,이명숙,이진영 한국주거학회 1999 한국주거학회 논문집 Vol.10 No.1

The purposes of this study were: 1) to classify and describe causes of producing wasted furniture and household electric appliances by consumers, 2) to identify the influence of variables on causes of producing wasted furniture and household electric appliances and experience of consumer`s recycling behaviors, and 3) to introduce the ways of activating recycling in wasted furniture and household electric appliances which suggested by consumers. 1,132 housewives living in Seoul, Sungnam, and Choongjoo were used as a final sample of the analysis. Data were collected using a self-administered survey. The result of the study indicated the major variable which affects producing wasted furniture and household electric appliances was the perception of recycling. Also, the level of consumers' recycling behavior in furniture and household electric appliances was very low and age and housing type were the major variables which affect consumers' recycling behavior. Finally, the implications and recommendations for consumers, enterprises, and society were suggested.

지구과학Ⅰ 교과서 어휘 등급 분석 : 살아있는 지구 단원을 중심으로

임영구,박혜진,이효녕,김태수,오희진 경북대학교 과학교육연구소 2008 科學敎育硏究誌 Vol.32 No.2

The purposes of this study were to analyze vocabularies used the section of ‘Living Earth’ in 11-grade Earth science textbooks with the Science Word Analysis (SWA) program and to investigate the vocabularies selected by the 11th grade students as difficult ones. For the purpose, we extracted the Earth science vocabularies from six textbooks, and classified into the scientific and non-scientific vocabularies with SWA program based on the standard Korean language dictionary. Also, we investigated the difficulty of each vocabulary by using questionnaire to three hundred sixty students. From the results analyzed with the program, it was found that the frequency of the scientific vocabularies out of the level was the largest any other level in all textbooks. And from the survey, most of the vocabularies selected by students as difficult to understand were classified into out of the level. From these results, it were suggested that the students’ cognitive level should be considered in developing science textbooks and difficult vocabularies should be replaced to easy ones within the limits of changeless in the meanings 이 연구의 목적은 11학년 지구과학 I 교과서의 ‘살아있는 지구’ 단원의 지구과학 어휘들을 SWA프로그램을 통해 분석하여 그 중 학생들이 어려워하는 어휘들을 알아보는데 있다. 연구 목적을 위해, 먼저 6종의 11학년 지구과학 I 교과서에서 지구과학 어휘들을 추출한 다음, 표준국어대사전을 기반으로 한 SWA 프로그램으로 과학 전문어와 비과학 전문어로 분류를 하였다. 분류된 과학 전문어와 비과학 전문어에 대해 360명의 11학년 학생들에게 이해하기 어려운 어휘를 선택하도록 하였다. 프로그램을 통해 어휘의 수를 분석한 결과, 교과서별로 다소 차이는 있지만, 등급 외의 과학 전문어 빈도가 모든 교과서에서 다른 등급에 비해 가장 높았다. 또한 학생들에게 설문한 결과, 어렵다고 하는 용어들의 대부분이 등급 외에 속해 있었다. 이 연구 결과를 통해, 교과서 집필 과정에서 학생들의 인지 수준을 고려해야 하며 어려운 용어는 과학적 의미의 변화가 없는 범위 내에서 쉬운 용어로 대체되어야 한다는 것을 제안하였다.