서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

제 삼대구치 발치의 병발증 : Deep Neck Infection, Mediastinitis, Plueral Effuison and Pericardial Effusion 심경부감염, 종격동염, 농흉, 흉막 삼출, 심낭 삼출

문재필,정창우,김은석 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

Severe complications like as mediastinitis, pericardial effusion from odontogenic infection are very rare in antibiotic era, but its mortality is very high when it occured. The sign and symptoms may be obscure sometimes, it is difficult to diagnose and treat the deep neck infection and other sequela exactly. The treatments of the complex odontogenic infection ares aggressive surgical drainage with placement of proper drain and administration of high dose of antibiotics as early as possible The authors report a case of complications induced from a third molar extraction.

都市 및 農村의 腸內 寄生蟲 感染에 關한 比較硏究 : 光州市 및 羅州郡 鳳凰面 地域을 中心으로

文宰奎,金宗中,文正錫,鄭駐炫 조선대학교 1981 The Medical Journal of Chosun University Vol.6 No.-

From the 1st of March to the 30th of April, 1979, this study on intestinal helminthic infections was carried ont on thc inhabitants, in Gwang-ju City and thc Bong-hwang Myun, Na-ju Gun area. The methods employed were Kato's cellophane thick smear technique in 603 cases (Gwang-ju City : 310, Bong-hwang Myun : 293) for the prevalence rate of various intestinal helminths ; the Scotch tape anal swab techniquu in 459 cases (Gwang-ju City : 223, Bong-hwang Myun : 236) for the prevalence rate of Enterobius vermicularis and Stoll's dilution egg-counting technique in all positive cases for the evaluation of the worm burden of some helminths. The results are as follows : 1. The positive rate of intestinal helminths of any kin was 80.1%(male: 75.0%, female : 85.1%) in Gwang-ju City ahd 92.6% (male : 90.6%, female : 94.5%) in the Bong-hwang Myun area by the cellophane thick smear technique. 2. The prevalence rate of Ascaris lumbricoides was 48.7% (male : 43.4:%, female : 52.9%, in Gwanag-ju City and 52.6%(rnale : 63.3%, female : 42.9%)in the Bong-hwang Myun area. 3. The prevalenec rate of Trichuris trichiura was 66.5%(male : 58.8%, female : 74.1%) in Gwang-ju City and 72.6%(male : 69.8%, female : 75.3%)in the Bong-hwang Myun. The highest prevalence rateamong helminths was in this area. 4. The prevalence rate of hookworm was 5.0%(male : 3.7%, female : 6.3%) in Gwang-ju City and 9.6%(male : 7.2%, female : 11.7%) in the Bong-hwang Myun area. 5. The prevalcncc raLe of Trichostrongylus orientalis was 4.8%(male : 4.4%., female : 5.2%) in Gwang-ju City and 6.2%(male : 7.2%, female : 5.2%) in the Bong-hwang Myun area. 6. The prevalence tate of Clonorchis sinensis was 1.4% (male : 2.2%, female : 0.6%.) in Gwang-ju City and 2.4%(male : 4.3%, female : 0.4%) in the Bong-hwang Myun area. It is higher in males than in femaless in the surveyed areas. 7. Taenia spp. was not foun in Gwang-.ju City and only 2 cases were found in the Bong-hwang Myun area. 8. The prevalence rate of Enterobious vermicularis was 29.1 %(male : 29.3%, female : 28.9%) in Gwang jn City and 31.3% (male : 29.5%, female : 33.1%) in the Bong-hwang Myun area by the Scotch tape anal technique. 9. The mean E.P.G. in Gwang-ju City be Stoll's dilution egg-counting technique was Ascaris lumbricoidis : 6,465 ; Trichuris trichiura : 600 : Hookworm : 392 ; Trichostrongylus orientalis : 256; and Clonorchis sinesis : 741. 10. The mean E.P.G. in the Bonag-hwang Myun area by the Stoll's dilution egg-counting technique wa s Ascaris lumbricoides : 7,231; Trichuris trichiura : 820 ; Hookworm : 592 ; Trichostrongylus orientalis : 341; and Clonorchis sinensis : 10,851.

土壤抗酸菌의 生體內 藥濟耐性 獲得에 對하여

鄭在奎,李相準,文榮石 慶北大學校 1964 論文集 Vol.8 No.-

In order to observe the appearance of drug resistant strains in vivo, soil acid fast bacilli (s-12) which exhibited and appearance in high frequency of drug resistant strains in vitro experiments, were inoculated into the mice, and three days after inoculation these mice were followed by treatment with streptomycin and isonicotinic amide hydrazid for 2 to 3 weeks according to the groups. After the cessation of treatment, mice of the each group were sacrificed and the drugs treated, on both two and three weeks treated groups, with a single exception of high druges treated, on both and three weeks treated groups, with a single exception of high resistant variant from on the liver lesion of the 3 weeks treated isonicotnic amid hydrazid group.

다발성 골수종으로 이행한 단일형질세포종 1예

정재용,모성환,기장도,문철호,김창욱,전용준,박유환,정춘해,오윤경 조선의대 1995 The Medical Journal of Chosun University Vol.20 No.2

農村住民의 農藥使用에 대한 知識, 態度 및 農藥中毒에 관한 硏究

文宰奎,정주현,鄭耀翰 朝鮮大學校 醫學硏究所 1982 The Medical Journal of Chosun University Vol.7 No.-

This survey has tried to investigate the respondents' characteristics, knowledge, attitude and poisoning in using pesticides in 7 Meyon districts of Cheollanambuk Do province, where 837 inhabitants were selected, during 4 months from July, 1981 to October, 1981, making use of questionaires. The results obtained from this study are as followings, 1. In purchasing pesticides, 49% of the respondents obtained it from an agricultural co-operative, and 34.3% of them from an agricultural co-operative and pesticide shops. 98% of them transported the pesticides separately. 2. 50.9% of the respondents kept the pesticides in a barn or a corner of the yard and 26.8% of them in a storehouse. 3. In spraying the pesticides, 56.5% of the respondents made plans for the spraying before hand and 8.6% of them were prepared for pesticide-poisoning before the spraying. 4. Before using the pesticide, 68.1% of the respondents always read an explanatory note and 83.3% of them examined the spraying equiment. 5. In the use of protection equipment against pesticide-poisoning, gloves were used by 19.5% of the repondents, masks by 81.6% goggles by 2.0%, boots by 11.1% and hats by 87.6%. 6. Spraying time for pesticide was 3-4 hour in 46.7% of the respondents, and averagely 4.1 hours. 47.8 of the respondents rested for 1-9 minutes during spraying the pesticides and 40.1% of them for 10-19 minute. 7. 42.9% of the respondents did not smoke during spraying the pesticides and 58.3% of them did not take a meal. 8. 72.8% of the respondents sprayed the pesticides against the direction of the wind and 26.0% of them sprayed regardles of the wind direction. 9. After spraying the pesticides, 67.7% of the respondents took a bath and 58.9% of them washed their equipment. 10. Pesticide bottles and package papers were buried under the ground by 38.1% by the respondents, dumped into the garbage by 32.5% of them and into fields by 13.4% of them, And 10.8% of the respondents returned them to the agricultural co-operative after collecting the bottles and package papers. 11. The remnants of the pesticides after spraying were kept safely for reuse by 52.8% of the respondents and dumped into a field by 23.3% of them. 12. 24.9% of the respondents used the pesticides only for agriculture, purposes and but 62.8% of them utilized them in disinfection of toilets and domestic sewage besides for the agricultral use. 13. Through abuse of pesticides, injury to man and beast, occured in 87.2% of the cases and 12.8% of them were indifferent to pesticides abuse. 48.1% of respondents recognized the destruction of the ecology but 48.9% of them did take no interest in the fact. 14. Knowledge for the pesticide-poisoning was acquired from their neighbours by 33.0% of the repondents, radio by 20.3% of them, leaders of the new village movement and the head of a village by 17.7%, a health center by 6.7% and newspaper and jounals by 4.9%. 15. 37.9% of the respondents had experience in pesticide-poisoning; The poisoning symptoms were, vertigo (35.3%), mausea (21.8%), headache (19.6%), dyspnea (8.2%), myatonia (5.0%), lacrimation (3.2%), and salivation (2.2%). 16. Frequency of experience of pesticide-poisoning was: the first time (51%), and 2nd time (21.5%), and 3rd time (14.2). After poisoning, 46.1% of the respondents took the rest, 41.2% of them went to a hospital and pharmacy, and 39.1% of them did not take any measures. 17. People engaged in agriculture for a long time had high frequencies of experience of pesticide-poisoning(P<0.05). 18. In cases in which emergency measures were prepared for pesticide-poisoning before using agricultural pesticides, rates of poisoning were significantly desreased(P<0.05).

黃龍江中流에 있어서 肝吸蟲症의 疫學的 調査硏究

鄭耀翰,文宰奎 朝鮮大學校 文理科大學 1975 論文集 Vol.2 No.-

Form 1st April to 30th October 1974, the epidemiological studies on Clonorchiasis were carried out on the 3,392 inhabitants who living in the middle area of the Hwang-Yong river. The stool specimens were examined with cellophane thick smear method and Stoll's dilution egg counting technique. The skin reaction with V. B. S. (veronal buffered saline) antigen was employed to the surveyed population. The results obtained are as follows. 1. The ova of C, sinensis was detected from 43.3% (male 47.9%, female 38.2%) of inhabitants by cellophane thick smear method and 44.7% (male 49.3%, female 39.8%) of inhabitants by skin reaction with V.B.S. antigen. 2. The infection rates by both skin reaction and cellophane thick smear method were getting higher with age and they were lower in young age groups. The infection rates were higher in male than in female by skin reaction and cellophane thick smear method. 3. The average E.P.G. was 9,103 (male 10.791 female 7,215). The average E.P.G in male was significanlty higher than in female. The average E.P.G. count of Clonorchis infection in the surveyed area was found higher among the higher age group. 4. The degree of the intensity of Clonorchis infection by E.P.G. count in the surveyed area was evenly distributed to the medium and heavy infection groups in the above 31 years old.

Hamlet의 Opening Scene

鄭在文 圓光大學校大學院 1988 論文集 Vol.2 No.-

In the Exposition, the dramatist must give the audience all the information that is necessary for his purpose : introdicing the characters, showing their position in life, their circumstances, their relations to one another etc. But he must tell the necessary information by means which is interesting, because the direct telling is unpleasant and undramatic. The opening scene of Hamlet, as the first part of teh Exposition, does its business very efficiently and interestingly. The first line of the play ("Who's there?") not only makes the noisy audience pay attention to the stage, but also implies the general inversion of the customary order of things. For the challenge was not asked by the sentinel on duty but by the relieving sentinel. Francisco's "Tis bitter cold, And I am sick at heart" comes naturally form the lips of a sentinel after a lonely watch, but it also supplies the tragic pitch. For Hamlet and Denmark will appear sick at heart soon. Barnardo, unwilling to stand this particular watch alone any longer than necessary, hopes that the partners of his watch will make haste. So even before Horatio enters to ask if "this thing" has again appeared, the audience are aware that the soldiers, in the cold and darkness of the night, are watching the hidden danger-something fearful and portending evil-which may threaten the present Danish Regime. Meanwhile, the audience are smoothly informed of the place (the platform of the battlement castle), the time (midnight), the season (bitter cold season) of this scene from the dialogues of the two sentinels. Horatio, who will not believe in the Ghost, agrees to hear the tale of the Ghost which appeared last night. At this point, when ominousness is at its fullest expression, the Ghost enters. The Ghost looks like the King Hamlet 'with that fair and warlike form.' Thus begins the process of inquiry which, in one form or another, runs throughout the play, and which may generally be described as an attempt to distinguish appearance from reality : Evil is immediately associated with this spirit, but there is countering suggestion (For it wears fair and warlike form). The imagery used by Horatio in his questioning is significant, since it introduces the theme of usurpation. The belief that the visitation of the ghost bodes some strange eruption to their state leads to accounts by Marcellus of the present situation of the state, and by Horatio of the threatened invasion by Fortinbras, As Horatio is speaking of harbingers of disaster, the Ghost enters again. Three motives commonly associated with haunting sperits are mentioned by Horatio, and one of these is that the dead may return because of earthly business left incomplete. The Ghost is majestical. But as soon as the cock crows it starts like a guilty thing upon a fearful summons. 'This bird of dawning' associated with Christian salvation makes as powerful as possible the contrast of day and night, normality and abnormality, good and evil. And the scene ends with an agreement to tell Hamlet, to whom the Ghost may speak. In conclusion, the opening scene of Hamlet smoothly introduces the main theme and the necessary information to the audience, and that makes it one of masterpieces of Shakespeare's opening scenes.

카드뮴을 투여한 랏드의 혈액 및 간조직 내의 카드뮴 농도의 문포형에 관한 연구

문재혁,박정덕,정규철 중앙대학교 의과대학 의과학연구소 1987 中央醫大誌 Vol.12 No.4

A group of 74 male rats of Sprague-Daweley strain was divided into serveral subgroups to which 0.1∼0.3% cadmium chloride soultions were adminsistered intraperitoneally by single injection of equivalent amount of 1∼32 ㎎/㎏ of body weight. the rats were sacrificed by decapitation at various intervals beinning from 3 hours to 14 days after a single injection. The cadmium concentrations in blood(㎍/l) and liver(㎍/g of tissue wet weight) were measured with atomic absorption spectrophotometer(Baird, Model A5100) by double beam flameless method. Cadmium concentrations in blood and those in liver were both log-normally distributed with logarithmic function on Y=-4.9204×1n Cd+27.7179 for the former and Y=-9.1557 1n Cd+40.7212 fot the latter. the frequency distribution of blood cadmium concentrations was also fitted to expoential and power function curves. Arithmatic means and standard deviations of cadmium concentrations in blood and those in liver were 78.6± 65.25㎍/l and 22.0 ±20.46㎍/g of tissue wet weight with coefficient of variations of 83.0% and 93.0%, repectively. On the other hand, geometric means and standard deviations were 57.0±2.90㎍/l and 15.1 ±2.42㎍/g of tissue wet weight for blood and liver, respectively. Skewness and kurtosis of distribution curves calculated on the basis of asithmatic frequency were 3.27 and 15.24 for the blood cadmium and 1,98 and 7,06 for the liver cadmium, whereas these valurs turned out to be 0.28 and 2.25 for the blood and 0.21 and 2.19 for the livrt when the log-transformed values of frequency were empolyed for calculation. Cummulative relative frequency of log-transformed cadmoum concentrations in blood and liver plotted on the normal probability paper showed a good linearity. The above findings indicate that the cadmium concentrations in blood and hepatic tissue are well fitted to the normal distribution curves when logarithmic transformations were made on these values.

急峻펄스 電壓을 利用한 强力오존發生裝置開發에 관한 硏究

文在德,吳哲洙,鄭華淑 경북대학교 1985 論文集 Vol.40 No.-

The power efficiency of ozone generation can be substantially improved by modifying a direct discharge wire of a wire-to-cylinder type ozone generator to a helical strip line. and using a fast rising pulse voltage on it. It is raised 1.3 times up of ozone yield compared with that of 60 gO_3/KWh of the industrial silent discharge type ozone generator. Parametric studies also made to get the optimum design of ozone generator tested. The generated ozone concentration had a peak value with proper increasing the crest pulse voltage, the quantity of a pulse forming condenser capacity of the pulse generator, and the interelectrode spacing of self triggered stainless steel spark balls. It is found that the optimum strip line length of the ozone generator tested was about 2m in view point of energy consumption. And, input and terminal impedance also effected greatly to ozone generation, the generated ozone concentration were increased when the input impedance had been 25Ω while the terminal had been opened.