국민 여가활동기회의 효율적인 분배와 생산유인 효과 확대를 위한 스포츠시설 및 스포츠 관련 산업의 관광자원화 방안을 위한 연구

남덕현,김천중,이주형 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.1

The purpose of this study is to examine the recognition and satisfaction of sport tourism as an area of tourism industry, and show the actual status of sport tourism, suggest the strategies to develop sport tourism goods according to sports tourism resources. This study is based on the survey of residents, physical education teachers, tour industry managers and local government employees, who were asked about what impact sports tourism had on local societies and environments. The data obtained from the returned questionnaire were coded and transcribed for a statistical analysis. collected data were analyzed though SPSS 10.0using such statical methods as a descriptive statistical analysis, chi square test, ANOVA test. With the twenty first century upcoming, sport tourism is recognized as a necessity of life for every person in the world. In addition, the rapid changes of social phenamenons such as the changing of a basic sense of value and life style. the improvement of income, the development of traffic systems, communication facilties, and medias, have a great influence on the desire for sport tourism. Compared with the past tourism that were mostly passive and superficial sight seeing tour, sport tourism is an active and exhilarating tour, therefore sport tourism could provide tourist with satisfaction of needs. Sports tourism is sure to become one of major industries. This study was done with the limited data, so the result does not fully represent the comprehensive impact of sport tourism and strategies of sport tourism resources.

중학교 가정과 교수-학습 방법의 개선을 위한 집단탐구 수업모형의 적용연구

남현주,유태명 한국 가정과 교육 학회 1996 한국가정과교육학회지 Vol.8 No.2

This study was to develop and to suggest a lesson plan for the area of 'Human Development and Family Relationship' in home economics for junior high school, based on Thelen's'Group Investigation Model', Group investigation model by Thelen was developed from the theory that the education with special purpose such as societic knowledge is a method to lesson one's conflict. This study further developed from three main concepts : inquiry, knowledge and activities of learning group. This model can be used for any age and any subjects in order to solve the arised problems, rather than to accept pre-organized and pre-decided information. This study is organized around activities for seeking and practicing the rages of action to create dispersal home. First, one unit 'Understanding of Family' was chosen that concerns and suitable for group investigation model Second, From the chosen chapter and problem were analyzed organized. Third, the chosen problem were re-analyzed, then a model lesson for group investigation was proposed.

난소암의 조기진단

남주현,목정은 울산대학교 의과대학 1993 울산의대학술지 Vol.2 No.2

Ovarian cancer is the leading cause of death from gynecologic malignancies. In 1992, it has been reported that the incidence of ovarian cancer was 3% of all female malignancies in Korea. During the last decade, the incidence of cervical cancer which is the most common one of female malignancies was gradually declining, however that of ovarian cancer tended to be slightly increasing probably because of changes in socioeconomic status of this country. Despite of aggressive debulking operation and intensive platinum-based combination chemotherapy, the overall survival rate for ovarian cancer has not changed appreciably over the last twenty years. One of the reasons for poor prognosis of ovarian cancer is that greater than 70% of patients with ovarian cancer is unfortunately detected after the disease has already spreaded beyond the pelvis because of the lack of early symptoms. The cure rate for these patients with advanced ovarian cancer is only 15-20%, This low survival rate is in marked contrast to that of as high as 90% with stage I disease. Therefore, development of early detection method for ovarian cancer would be the best way to reduce the mortality rate of this disease. Ultrasonography and serum tumor marker, CA 125 have been extensively studied for early detection of ovarian cancer. Recently, combined use of transvaginal color Doppler technique is studied to increase the specificity of the screening test. However, the value of these methods as a screening test is still debating. So far, unfortunately there is no conclusive method which has cost-effectiveness and perfect sensitivity and specificity for ovarian cancer screening. Moreover, the optimal population and interval for ovarian cancer screening are not currently defined. In this review, recent data of studies using ultrasound and serum marker, CA 125 and debating issues for ovarian cancer screening are discussed.

동결온도가 해동 쇠고기의 품질에 미치는 영향

남주현,송형익,김미숙,문윤희,정인철 한국식품영양학회 1998 韓國食品營養學會誌 Vol.11 No.5

동결온도가 해동우육의 품질에 미치는 영향을 검토하였다. 해동드립감량은 -3℃ 동결이 30일째에 3.4%, -20℃ 동결이 60일째에 1.8%로 높았으며, -3℃가 -20℃보다 드립량이 많았다. 가열감량은 water bath와 pan 가열 모두 저장초기보다 동결저장중에 현저하게 높았으나, 동결온도에 의한 차이는 없었다. 염용성 단백질의 추출성은 동결기간이 경과함에 따라 감소하였고, -20℃에서 동결한 것이 -3℃에서 동결한 것보다 추출성이 높았다. 수용성 단백질의 추출은 -3℃의 경우 동결기간에 따라 현저한 변화가 없었으나, -20℃에서 동결한 것은 동결기간에 따라 증가하는 경향을 보였다. 명도(L)는 동결초기가 높았고 적색도(a)는 동결기간에 따른 변화가 없었으며, 황색도(b)는 동결초기보다 동결중에 더 높았다. Myoglobin의 변성율은 -3℃의 경우 45일째, -20℃의 경우 15일째 각각 94.4%와 94.0%로 가장 높았다. 전단력가는 동결초기보다 저장기간이 경과함에 따라 높아졌으며, 근원섬유의 소편화도는 동결저장중 현저한 변화가 없었다. pH는 -3℃와 -20℃ 모두 30일째까지 높아지다가 그 이후 낮아지는 경향을 나타내었다. This study was carried out to investigate the effects of freezing temperature on quality of thawed beef loin. In case of thaw drip loss, the freezing of -3℃ and -20℃ were higest by 3.4% to 30 days and by 1.8% to 60 days, respectively. And the thaw drip loss of -3℃ freezing was more than -20℃ freezing. The cooking loss of water bath and pan boiling were increased significantly during freezing than the beginning of freezing, but were not different -3℃ and -20℃. The salt soluble protein extractability was decreased during freezing, the -20℃ freezing was higher than -3℃ freezing. The water soluble protein extractability of -3℃ freezing was not significant different during freezing storage, that freezed at -20℃ was increased during freezing. The "L" value of the beginning of freezing was higher than during freezing, the "a" value was not different during freezing, and the "b" value during freezing was higher than the beginning of feezing. The myoglobin denatured percentaged of the -3℃ and -20℃ freezing were highest by 94.4% to 45 days and by 94.0% to 15 days, respectively. The shear force value during freezing was higher than the beginning of freezing, the myofibrillar fragmentation index was not significant different during freezing. The pH was increased to freezing 30 days, after that was decreased.

흡연 및 비흡연 정신분열증 환자간의 인지 기능과 치료 반응의 차이

남궁기,민성길,이희상,조현상,김세주 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.4

연구 배경 : 본 연구는 정신분열증 환자에서 흡연 여부에 따라 정신분열증 환자군의 정신과적 과거력 및 현재 증상, 치료 반응과 인지 기능 등에 어떤 차이가 있는 지를 알아보려는 것이다. 연구 방법 : 정신분열증 환자 중 36명의 흡연군과 31명의 비흡연군을 연구 대상으로 하였다. 현재의 증상을 평가하기 위해서 양성 및 음성 증상 척도(Positive & Negative Syndrome Scale) 및 전반적 기능 평가 척도(Global Assessment Scale)를 상용하였고, 추체외로계 부작용을 추체외로계 부장용 평가척도(Rating Scale for Extrapyramidal Side Effects)로 측정하였다. 흡연군과 비흡연군의 인지 기능을 평가하기 위해 비엔나 검사 중 SPM(Standard Progressive Matrices), Cognitron 및 FFA(Flicker Fusion Analyzer) 검사를 실시하였다. 연구 결과 : 1) 흡연군과 비흡연군에 비해 유병 기간이 유의하게 길었음에도 불구하고, 입원 시의 증상 정도(PANSS 총점)가 유의하게 낮았고, 기능 정도(GAS 점수) 역시 유의하게 높았다. 2) 정신분열증의 치료 반응에 영향을 미칠 것으로 생각되는 나이와 유병 기간을 통제한 상태에서 흡연여부에 따른 치료 반응의 차이를 검증해 본 결과, 흡연 여부에 따른 일일 약물 사용량, 추체외로계 부작용 및 증상 호전율(PANSS 호전율)이나 기능 호전율(GAS 호전율)에 유의한 차이는 없었다. 또한 인지 기능에 영향을 미칠 것으로 생각되는 나이, 유병 기간, 항전신병약물 용량 및 증상의 정도를 통제한 상태에서 흡연 여부에 따른 인지 기능의 차이를 검증해 본 결과, 흡연 여부에 따른 SPM 값, COG-R 및 FFA 갑의 차이는 없었다. 3) 흡연군 내에서 흡연 정도와 치료 반응 및 인지 검사 점수와의 관계를 알아보기 위해, 나이와 유병 기간 요인을 통제한 상태에서 일일 평균 흡연량과 여러 임상 척도와의 상관 관계를 분석해 보았다. 그 결과 일일 흡연량과 증상 호전율(PANSS 호전율) 이나 기능 호전율(GAG 호전율) 사이에 통계적으로 유의한 상관 관계를 보였다. 그러나 총 흡연 기간은 치료 반응 및 인지 기능과는 통계적으로 유의한 상관 관계를 보이지 않았다. 결 론 : 이상의 결과를 종합해 보면 흡연 정신분열증군은 비흡연 정신분열증군에 비해 입원 시 증상이 경미하고 기능이 좋으며, 흡연 정신분열증군에서는 흡연량이 많을수록 치료 시 증상 및 기능이 호전율이 높다고 할 수 있다. 그러나 흡연군에서 일일 약물 사용량이 높다거나, 추체외로계 부작용이 덜 나타난다거나 지능 저하가 덜하다는 이전의 연구 결과들은 입증되지 않았다. Objectives : The purpose of this study was to examine the differences of past histories, current symptoms, treatment responses and cognitive and functions between smoking and nonsmoking schizophrenic patients. Methods : The subjects were composed of 67 schizophrenic patients including 36 smokers and 31 non-smokers. They were examined by psychiatric history checklist, Simpson and Angus's rating scale for extrapyramidal side effects, positive & negative syndromes scale(PANSS), global assessment scale(GAS), and Vienna test including Standard Progressive Matrices(SPM), Cognitron, and Flicker Fusion Analyzer(FFA). Results : The results were as follows : 1) Although the duration of illness of smokers was longer than that of non-smokers, the smokers had significantly higher score of GAS and significantly lower score of PANSS than non-smokers at admission. 2) With effects of age and duration of illness controlled, there were no differences of mean dosage of neuroleptics, extrapyramidal side effects, PANSS improvement rate and GAS improvement rate between both groups. 3) With effect of age, duration of illness, and total PANSS score controlled, there were no differences of score of SPM, cognitron, and FFA. 4) In smokers, the PANSS improvement rate and the GAS improvement rate were positively correlated with mean number of daily smoked cigarettes, with effects of age and duration of illness controlled. Conclusions : In schizophrenic patients, smokers had less severe symptoms than non-smokers. In smokers, the PANSS improvement rate and the GAS improvement rate were positively correlated with mean number of daily smoked cigarettes. But Smokers were not proven to have received higher dosage of neuroleptics, to have lower extrapyramidal side effects, or to have less severe impairment of cognitive function.

기능상실한 이식신의 절제

조원현,남창우,김천일,주일,박성배,김현철 大韓移植學會 1994 Korean Journal of Transplantation Vol.8 No.1

2003년도 해양스포츠 체험활동을 통한 소아건강교실 사례 발표

김현주,이상엽,이가영,곽현,이남수,김혜선,김윤진,김인주,김용기,대학비만학회 부산분과학회 일동 대한비만학회 2003 The Korean journal of obesity Vol.12 No.4

서울시내 치과의원의 소독기 실태

권주현,김성태,김광만,김경남 대한치과기재학회 1997 대한치과재료학회지 Vol.24 No.2

Sterilizer is one of the necessary equipments in dental clinics for aseptic treatment. There are many types of sterilizer, such as autoclave, chemiclave, dry heat sterilizer, UV(Ultra Violet) sterilizer, boiling sterilizer, EO(Ethylene Oxide) gas sterilizer, by sterilizing mechanis. To evaluate the type and sterilizing ability, one surveyer visited 100 dental clinics in Seoul and surveyed some items, such as age and gender of dentist, type, location and using period of sterilizer, how many sterilizing time per day and who operate sterilizer, so on. As preacticall operation the sterilizer, sterilized basillus subtilis in test tube and incubated it. Then it's turbidity was observed. The results were as follows 1. The descending order of plenty were autoclave(68), UV sterilizer(26), chemiclave(12), dry heat sterilizer(4) and boiling sterilizer(2). 2. The descending order of sterilizing ability were dry heat sterilizer(100%), autoclave(89%), chemicloave(73%), UV sterilizer(43%) and boiling sterilizer(0%). 3. Sterilizing ability in dental clinics that have both sterilizer, autoclave and UV sterilizer, chemiclave and UV sterlilzer was low than single sterilizer(autoclave, chemiclave). 4. The descending order of location of sterilizer were treatment room, laboratory room, sterilizing room and the order of operator were assistant, hygiene and both assistant and hygiene.

2003년도 해양스포츠 체험활동을 통한 소아건강교실 사례 발표

김현준,이상엽,이가영,곽현,이남수,김혜선,김윤진,김인주,김용기,대한비만학회 부산분과학회 일동 대한비만학회 2003 The Korean journal of obesity Vol.13 No.4

부산에 소재한 3개 초등학교 청소년단체 소속의 초등하교 3학년부터 6학년까지 구성된 172명을 대상으로 청소년단체 지도자, 초등학교교사, 자원봉사자, 의사와 영양사가 1박 2일간의 해양스포츠 체험활동 을 통한 건강교실을 시행하였다. 대상자의 체질량지수, 체지방량을 측정하여 비만정도를 평가하였으며, 칼로리 섭취에 대한 강의를 시행하였고, 설문지 조사를 통해 대상자의 식이 섭취 습관에 대한 조사를 시행하였고, 본 건강교실에 대한 만족도를 측정하였다. 대상자중 남자에서는 40%, 여자에서는 25.69%에서 비만 경향을 보였다. 대상자의 대부분에서 시행된 건강교실에 긍정적 반응을 보였으며, 향후 체계적인 구성과 철저한 사전계획이 병행되어 본 증례 보고와 같은 건강교실을 시행한다면, 비만아동에서 거부감 없이 비만에 대한 교육을 실시할 수 있으며, 정상 체중 아동군에서도 비만에 대한 예방교육을 시행할 수 있는 프로그램이 될 것이다. 172 elementary school students involved this health program. This subjects were learened about obesity that affect health problem, ideal eating habits, calories that contained in the children's favorite foods by doctors and nutritionist. And this stubjects were checked heights, weight, body fat percent. Obesity is 40% in the boys and 25.69% in the girls. Most subjects were satisfactory with this health program. So we will effectively educate obese children without resistance and prevent normal weight children from obesity through structured and well-designed health program that similar to this program.

Paclitaxel 및 Apo-2L/TRAIL이 자궁경부암 세포주 아포토시스에 미치는 영향

김주영,남계현,김태희,이권해,이해혁,배동한 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.2

Objective: TRAIL(also called Apo-2L) is a member of the tumor necrosis factor(TNF) family of cytokines which induces apoptosis cell death in a variety of tumor cell lines. It mediates its apoptotic effects through one of two receptors, DR4 and DR5, which are members of the TNF receptor family, and whose cytoplasmic regions contain death domains. TNF and Fas ligand induces apoptosis in tumor cells; however, their severe toxicity toward normal tissues hampers their application to cancer therapy. We examed if paclitaxed and/or Apo-2LTRAIL induces apoptosis of cervical cancer HeLa, SiHa, ME-180, and CaSki cells. Mehods : We have demonstrated that paclitaxel and Apo-2L/TRAIL induces apoptosis of cervical cancer HeLa, SiHa, CaSki and ME-180 cell lines in a dose-dependent manner. HeLa, SiHa, ME-180 and CaSki were obtained from American Type Culture Colection. Recombinant Human TRAIL(Chmicon). DR4 and DR5 were purchased from Santa Cruz. Paclitaxel, MTT assay Kit, Acridine orange and Ethium bormide were purchased from Sigma. HeLa and SiHa were grown in DMEM. ME-180 and CaSki were grown in RPMI. Tripan blue stain and MTT assay were done for cytotoxicity. Annexin V-FITC and PI(propidium iodide) flowcytometry for apoptosis assay. DR4 and DR% were expressed by Western Blot. Fluorescent Microscopy used Acridine orange(AO) and Ethium bromide(EB). Results : Importantly, concurrent treatment of cervical cancer cells with paclitaxed and Apo-2L/TRAIL induces significantly more apoptosis than Apo-2L/TRAIL alone. Conclusion : We need further studies which reveals possible therapeutic potential in the women with cervical cancer by suing Apo-2L/TRAIL.