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      • 서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

        김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

        In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

      • KCI등재

        페트리네트를 이용한 FMS스케줄링에 대한 발견적해법

        안재홍,노인규 한국경영과학회 1996 韓國經營科學會誌 Vol.21 No.2

        The main purpose of this study is to develop an algorithm to solve the scheduling problems of FMS using Petri-net which describes exactly features of discrete event system. Petri-net is well suited to model the dynamics of FMS and Petri-net is an ideal tool to formulate scheduling problems with routing flexibility and shared resources. By using the marking of Petri=-net, We can model features of discrete event system, such as concurrency, asynchronous, conflict and non-determinism. The proposed algorithm in this paper can handle back-tracking using the marking of Petri-net. The results of the experiment show that marking is one of the best ways that describe exactly movement of the discrete event system. To show the effectiveness of the algorithm suggested here, we compare it with L1 algorithm using the Petri-net through the test on randomly generated test problems.

      • 질편모충(Trichomonas vaginalis)의 시험관내에서의 용혈능

        안명희,류재숙,홍택원,민득영 한양대학교 의과대학 1995 한양의대 학술지 Vol.15 No.2

        To evaluate the hemolytic activity of T. vagindlis from Korean women and fresh human RBC of A type were nsed for hemolytic assay. RBC(1×10 /ml) was added to RPMI-TPS media(RPMI 1840:TPS-1= 20 : 1) containing T. vaginalis(2×10 ) and incubated at 37℃, 5% CO₂incubator for 6hr and hemolysis was measured by spectrophotometer at 412m. We investigated the parasite to erythrocyte ratio and lemperature needed for hemotysis. Optimal erythrocyte lysis by T. vaginalis was achieved at ratio of 1 : 5 and optimol temperature 37℃. Minimal hemolytic activity was detected in lysates of T. vaginalis. No hemolysis occured when a membrane a 3㎛ pore size was nsed to prevent contact between parasites and erythrocytes. These data suggest a need for contact for trichomonol hemolysis. Hemolytic activity did not correlated with the production of subcutaneous abscess in mice.

      • 통계적 기법을 이용한 마이크로 스피커 다이아프램의 최적형상설계에 관한 연구

        안찬우,홍도관,최재기,박진우 東亞大學校附設 生産技術硏究所 2007 生産技術硏究所硏究論文集 Vol.12 No.-

        This study uses response surface methodology to explain correlations between the objective function and design variables, fractional factorial design and central composite design were carried out. The change of shape of diaphragm, thickness of diaphragm and voice coil weight based on fractional factorial design and central composite design are made. Therefore this study carried to decide design variables for minimizing 1st natural frequency and maximizing 2nd natural frequency of diaphragm using response surface methodology and screening(fractional factorial design), we showed improved design variables.

      • 성남시 어린이집 원아 어머니의 구강보건의식과 행태에 관한 조사연구

        안용순,김은숙,임도선,정세환,이홍재 한국구강건강증진학회 2000 한국구강건강증진학회지 Vol.1 No.1

        The purpose of this study was to evaluate behaviour about oral health of child's mothers in Songnam city, to obtain the data on oral health programs for young child of child care institutions. A self-developed questionnaire with 10 items was delivered to 713 mothers. Mothers were selected by a cluster sampling method. The 662 collected data was analyzed by profession state. The obtained results were as follows : 1. The house wives without job didn't appear the better behaviors about child's oral health than those with job except child's tooth brushing number per day. 2. There were needed to develop mothers' education program, caries prevention program, periodic oral exam program, refer system program after oral exam and tooth brushing program. 3. The 10 subjects were enumerated by contents of mothers' education program.

      • KCI등재후보

        Streptococcus constellatus에 의한 경막 외 농양이 동반된 화농성 척추염 1예

        안홍대,박재찬,서종구,김진용,김수연,박윤수,서일혜,조용균 대한감염학회 2008 감염과 화학요법 Vol.40 No.5

        We report a case of vertebral osteomyelitis with epidural abscess caused by Streptococcus constellatus. The patient was present with fever, back pain, and dyspnea for 1 week. The patient was previously healthy and did not have any predisposing factor. After evaluation, the patient was diagnosed as Streptococcus constellatus vertebral osteomyelitis. He was successfully treated with surgical debridement and antibiotic therapy. To the best of our knowledge, this is the first case of S. constellatus vertebral osteomveltis with epidural abscess to be reported in Korea.

      • KCI등재

        6세 이하의 어린이에서 Streptococcus mutans와 Streptococcus sobrinus의 분포에 관한 연구

        안승태,박재홍,이긍호 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.2

        Mutans streptococci는 치아우식증과 관련이 있다고 보고 되고 있으며, 이 streptococci 종 중에서 S. mutans나 S. sobrinus가 인간의 치아우식증에서 가장 일반적으로 나타난다. 치아우식증에서 이 세균종의 분포는 인종과 지역에 따라 다양하다. 본 연구에서는 2-6세인 52명의 치아우식증 환자에서 비우식부위와 우식부위로부터 치태를 채취하여 DNA를 추출한 dex와 gtf 유전자에 기초한 S. mutana와 S. sobrinus에 특이한 primer를 제작한 후 PCR을 시행하여 S. mutans와 S. sobrinus의 분포도를 조사하여 다음과 같은 결과를 얻었다. 1. 어린이 치아우식증 환자에서 S. mutans나 S. sobrinus가 발견된 어린이는 37명 (71.2%)이었다. 2. 이들 어린이 중에서, S. mutans 또는 S. sobrinus가 비우식 부위에서만 발견된 어린이는 3명(5.8%), 우식 부위에서만 발전된 어린이는 22명(42.3%), 두 부위 모두에서 발견된 어린이는 12명(23.1%)이었다. 3. S. mustans나 S. sobrinus가 나타난 비우식부위 치태는 15개 (28.8%), 우식부위 치태는 34개(65.4%)였다. 4. 비우식부위의 경우 S. mutans만 출현한 어린이는 52명 중 8명(15.4%), S. sobrinus만 출현한 어린이는 6명(11.5%), 두 세균종이 같이 출현한 어린이는 1명 (1.9%)이었다. 5. 우식부위에서 S. mutans 출현한 어린이는 52명 중 24명(46.2%), S. sobrinus만 출현한 어린이는 2명(3.8%), 두 세균종이 같이 출현한 어린이는 8명 (15.4%)이었다. 6. S. mutans는 gtf에 기초한 primer, S. sobrinus는 dex에 기초한 primer가 PCR에서 효과적으로 각각의 세균을 검출하였다. 이상의 결과로 미루어 우리나라 어린이의 경우 치아우식증은 MS와 밀접한 연관성이 있으며, MS중에서도 S. mutans가 중요하다고 판단된다. 한편 S. mutans와 S. Sobrinus의 동반출현은 치아우식증과 더욱 밀접한 관련이 있는 것으로 보인다. Mutans streptococci have been reported to be implicated in dental caries. Of these streptococcal species, Streptcoccus mutans and Streptococcus sobrinus are most commonly found in human dental caries. Prevalence of these bacterial species in dental caries is found to be varied in different races and countries. Therefore, importance of these bacteria in dental caries remains to be determined. The present study was performed to detect S. mutans and S. sobrinus in 52 Korean children with dental caries between 2 to 6 years of age. For the study, plaque samples were collected from caries-active(CA) and caries-free(CF) teeth of each subject. DNA was extracted from the plaques and amplified by polymerase chain reaction(PCR) using primers corresponding to dex and gtf genes. The results obtained from the study were as follows: 1. Of 52 children, 37 children (71.2%) were found to harbor S. mutans and/or S. sobrinus. 2. Of the MS-infected 37 children, 3 children (5.8%) harbored S. mutans and/or S. sobrinus in the CF plaques only, 22 children (42.3%) in the CA plaques only and 12 children (23.1%) in both CF and CA plaques. 3. S. mutans and/or S. sobrinus were detected in 34 CA plaques (65.4%), while 15 in CF plaques (28.8%). 4. In the case of CF plaques, 8 plaques (15.4%) were observed to harbor S. mutans only, 6 plaques (11.5%) to harbor S. sobrinus only and 1 plaque (1.9%) to harbor both species. 5. Of CA plaques, 24 plaques (46.2%) were detected to have S. mutans only, 2 plaques (3.8%) to have S. sobrinus only and 8 plaques (15.4%) to have both species. 6. In comparison with the efficiency of two different primers for PCR, it was found that the primer based on gtf gene was more effective in detecting S. mutans, while the primer corresponding to dex gene was better for S. sobrinus. Overall results suggest that MS appears to be important in dental caries of the Korean children, and S. mutans is more closely associated with than dental caries as compared to S. sobrinus.

      • SCOPUSKCI등재

        신장이식 환자의 근력, 근지구력, 유연성 및 일상생활활동의 변화

        안재현,하희선,홍정자 성인간호학회 2001 성인간호학회지 Vol.13 No.1

        The purpose of this study was to explore the change of muscle strength, muscle endurance, flexibility and activities of daily living to develop a rehabilitational program. The subjects were selected randomly among the patients who underwent kidney trans- plantations at one major transplantation hospital in Seoul, Korea. This study was carried out between November 23, 1999 and February 15, 2000. The subjects in this study consisted of 16 patients who had kidney transplantations between 1 month and 12 months ago prior to this study. They were all on steroids and did not take any physical exercise regularly. The muscle strength, muscle endurance, flexibility and activities of daily living were evaluated at 1st week and after 12 weeks. The data were analyzed with numbers, percentiles, mean, standard deviation and t-test. The results were as follows : 1.After 12 weeks, the grip strength was significantly decreased than 1st week(p =.0002). 2.After 12 weeks, the back lift strength was significantly decreased than 1st week(p =.0002). 3.After 12 weeks, the muscle endurance was increased than 1st week, but it was not significant(p=.5487) 4.After 12 weeks, the flexibility was significantly decreased than 1st week(p=.0002). 5.After 12 weeks, the activities of daily living was significantly decreased than 1st week(p=.0006). Like the above result, the kidney transplant receipients' muscle strength, flexibility and activities of daily living were reduced In order to solve this problem, the writer has found that program development to prevent the defects should be extremely required. Since now on the number of patients should expand. After the kidney transplantation, the periods of 4, 8, 12 and 16 weeks are extended. The writer proposes to examine the different phase of change in each periods.

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