서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

유도선수들의 스포츠자신감 수준이 귀인형태에 미치는 영향

홍재표,차정훈,전승훈 한국스포츠리서치 2005 한국 스포츠 리서치 Vol.16 No.2

The present study was designed to examine the effect of sport-confidence on attributional perceptions across male and female fencers. Judo athletes reported their sport-confidence, attribution perceptions on Sport-Confidence Inventory. CDSⅡ(Causal Dimension Scale Ⅱ) According to the previous research findings related to the theme of the study, it was hypothesized that the independent variables of trait sport-confidence. state sport-confidence influence the dependent variable of attributional perceptions. and the relationships between the two kinds of variables were examined using two-way ANCOVA. The implications of the study are as follows : Firstly. Trait sport-confidence and state sport-confidence of judo athletes significantly affected the locus of contorl dimension. Secondly. Trait sport-confidence and state sport-confidence of judo athletes significantly affected the stability dimension. Thirdly, Trait sport-confidence and state sport-confidence of judo athletes significantly affected the contro lability dimension.

대용량 어휘를 기반으로 한 화자의 적용 알고리즘

홍승준,권영헌,이건상 한양대학교 이학기술연구소 2001 이학기술연구지 Vol.3 No.-

화자독립인식기의 평균적인 성능은 좋더라도 사용하는 화자에 따라 인식률이 많이 차이가 난다. 이러한 문제점을 해결하기 위한 방법으로 본 논문에서는 기존의 codebook을 사용하여 사용자의 적은 어휘로써 높은 인식률을 가질 수 있는 화자 적응 방법을 제안한다. 본 논문에서는 대용량 어휘인식을 위해 음소인식에 뛰어난 성능을 지닌 CHMM(continuous hidden Markov model)을 사용하였고, 적응 알고리즘인 MAP(maximum a posterior)를 사용하여 HMM의 파라미터를 적응시키는 방법으로 대용량 어휘 인식률을 계산하였다. 화자 적응 알고리즘을 적용하기 이전과 화자 적응 알고리즘을 적용했을 때 인식률을 비교하였을 경우 음소 인식률이 40%이상 좋아짐을 알 수 있었다. In this paper. we propose a speaker adaptation algorithm. We make an experiment using CHMM which shows good performance for phoneme recognition. MAP formulation is developed to adapt the characteristics of speaker with the estimation of the HMM parameter from the training data. The proposed adaptation algorithm is evaluated in large vocabulary continuous speech recognition. In the experiment. we compare the recognition accuracy of the adapting acoustic model with that of common speaker. At the experimental results. MAP algorithm achieve up to about 40% additional reduction of error in phoneme recognition.

난소의 성국 낭성기형종에서 관찰된 전립선 조직 - 1예 보고 -

홍승모,최미선,한은미,이현경,노재윤 대한병리학회 1999 Journal of Pathology and Translational Medicine Vol.33 No.7

화자 식별과 얼굴 인식을 이용한 대규모 보안 시스템

홍승준,구자윤,권영헌,이건상 한양대학교 이학기술연구소 2000 이학기술연구지 Vol.2 No.

본 논문에서는 화자 식별과 얼굴 인식을 이용하여 대규모 보안 시스템을 개발하였다. 인식 에러를 줄이기 위해 전 처리 화자 식별기로 DHMM(Discrete hidden Markov Model)을 사용하였고, 후 처리기에서는 얼굴 인식을 위해 신경망을 사용하였다. Visual C++MFC을 사용하여 Sound Card와 Digital camera를 제어하였다. 그리고 본 논문에서 개발한 프로그램을 사용하여 실시간으로 실험하였다. 본 논문에서 인식에 사용한 특징 벡터로는 Filter bank energy, LSF와 Cepstrum coeffient이고, 얼굴 인식의 대표 벡터는 2차원 Filter bank energy를 사용하였다. 실험에서 사용된 사람은 학교에서 무작위로 83명을 선택하였다. Test를 위해 2049개의 음성 데이터와 365개의 얼굴 이미지를 사용하였다. 복합 모델로 구성한 본 시스템은 등록화자에 대해 98.8%의 Access rate와 비 등록화자의 99.82%의 deny rate을 나타내었다. In this paper, we developed the large scale security system using speaker identification and face recognition. In order to reduce the recognition error we used DHMM(Discrete Hidden Markov Model) in speaker identification for pre-processor and neural network in face recognition for post-processor. To test the on-line performance of total system we directly controlled the sound card and the digital camera in the environment of Visual C++MFC. And we developed the program to test the performance of the system in real time. We used filter bank energies, LSF and cepstrum coefficients as the feature vectors of speech, and the 2-dimensional filter bank energies extracted in the range of the representative feature on face. In experiments, we randomly selected 83 persons in school, and then chosen 10 persons as an enrolled person and 73 persons as a non-enrolled person. So we tested 2049 speech data and 365 image data. It turned out that the hybrid system would have 98.8% access rates for the enrolled persons and 99.82% deny rates for the non-enrolled persons.

외상성 뇌지주막하출혈을 동반한 두부외상 환자의 예후인자

길승배,김헌주,허철,한용표,홍순기,변진수 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.9

The presence of traumatic subarachnoid hemorrhage on the initial computerized tomographic scans has been known to be associated with worse results. By means of a simple and reliable computerized tomographic grade system proposed by Greene and his colleagues, prognostic factors of the traumatic subarachnoid hemorrhage was significantly related to clinical outcome at the time of discharge from acute hospitalization. Between February 1992 and August 1995, 3975 patients were admitted to our department of neurosurgery due to head injury. Clinical data were retrospectively reviewed to ascertain the relationship of the thickness of traumatic subarachnoid hemorrhage, its location, evidence of mass lesion(s), midline shift, obliteration of the basal cistern, and cortical sulcal effacement to outcome. Additionally initial Glasgow coma scale score, arterial gas study systemic blood pressure and prothrombin time were also analyzed for the same purpose. Among 3975 head-injured patients. 213 patients were identified to have traumatic subarachnoid hemorrhage on the initial computerized tomographic scan. Among 213 traumatic subarachnoid hemorrhage patients, the patients treated with calcium channal blocker(32 patients) and 3 patients lost to follow-up were excluded from this study for a total of 178. The computerized tomographic scan findings were divided into a 3 grade system : Grade 1 indicating only traumatic subarachnoid hemorrhage. Grade 2 indicating traumatic subarachnoid hemorrhage with mass lesion(s). Grade 3 indicating traumatic subarachnoid hemorrhage with mass lesion(s) and midline shift. All these data were compared to Glasgow outcome scale on discharge, and arbitarily these were divided into the good(good recovery and moderate disability) and the bad(severe disability, vegetative state and death). The authors conclude that the contributing factors to outcome at discharge were as follows : 1 midline shift(p=0.002), PT≤70%(p<0.001), obliteration of the basal cistern(p=0.001) and cortical sulcal effacement(p=0.001) were shown to the statistically significant. 2. initial computerized tomographic grade contributed to outcome at discharge.

유백피 메탄올 추출물에 의한 Melanin 합성 조절

정승일,김춘관,전병훈,백승화,우원홍,천현자 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.5

Melanogenesis is a physiological process resulted in the synthesis of melanin pigments, which have a role in protecting skin from the damaging effect of ultra-violet(UV) radiation. The main aim of the present study was to examine the effect of Ulmus davidiana var. japonica on melanogenesis. Cells were cultured in the presence of methanol extracts from Ulmus davidiana var. japonica for 48 h, and there were estimated total melanin content as a final product and activity of tyrosinase, a key enzyme, in melanogenesis. Methanol extracts of the bark Ulmus davidiana var. japonica increased tyrosinase activity and melanin contents in a dose-dependent manner. Especially, It was observed that only 100 μg/ml methanol extract stimulates melanin secretion in B16/F10 melanoma cells by 140% at 48 h treatment and activity of tyrosinase increased by 250 % in the presence of same concentration.

소뇌에 발생한 과립구성 육종 : 증례보고

윤승환,변진수,홍순기,김헌주,한용표,양재승,조미연 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.8

Granulocytic sarcoma, a rare extramedullary solid tumor arising from early myeloid precursors, is capable of invading the meninges or the brain parenchyma. The tumor may occur during or after the onset of systemic myelogenous leukemia. On rare occasions, the tumor may evolve before the onset of systemic myelogenous leukemia. Children are affected more often than adults, but sex is not related. Although no definite target area of the brain can be demonstrated, there may be some predilection of the tumor for the posterior fossa. The authors report a case of 4-year-old-boy with granulocytic sarcoma occuring in the posterior fossa presenting with gait disturbance and torticollis. The patient was treated by surgical removal of the tumor, thereby avoiding the potentially lethal complication of a posterior fassa mass. This rare case is reported together a review of the literature.

Ribosomal DNA의 ITS영역 염기서열 분석에 의한 기주특이적 독소 생성 Alternaria spp.의 계통분류학적 유연관계

高昇柱,洪承範,姜熙玩,劉勝憲,柳震彰 충남대학교 생물공학연구소 1998 생물공학연구지 Vol.6 No.-

기주특이적 독소 생성 Alternaria spp.와 비병원성 A. alternata의 계통분류학적 유연관계를 규명하기 위하여 기주특이적 독소 생성 Alternaria 6균, 비병원성인 A. alternata 그리고 비교균으로서 소형포자를 형성하는 A. brassicicola, 대형포자를 형성하는 A. solani의 ribosmal DNA의 5.8S를 포함한 ITS영역의 염기 서열을 분석하였던 바 다음과 같은 결과를 얻었다. 1. Alternaria spp.의 rDNA ITS영역의 염기서열 크기는 548∼562bp였으며 5.8S rDNA에서는 비교종간에 서로 일치하였고 ITS I에서는 종간 뚜렷한 차이를 보였다. 2. 기주특이적 독소 생성 Alternaria spp.의 rDNA의 ITS영역의 염기서열은 비병원성인 A. alternata의 염기서열과는 서로 일치하였으나 A. brassicicola와는 3%, A. solani와는 7%의 염기서열 차를 보였다. 3. 기주특이적 독소 생성 Alternaria spp.는 비병원성 A. alternata와 진화적으로 매우 가까운 유연관계를 나타내었다. The regions of internal transcribed spacer(ITS) including 5.8S ribosomal DNA(rDXA) from six host-specific toxin(HST) producing Alternaria spp. nonpathogenic A. alternata. A. solani and A. brassicicola were sequenced to assess their relationship in taxonomy. There was no difference in the sequences of ITS including 5.8S rDNA among the HST-producing Alternaria spp. and nonpathogenic A. alternata. However, the sequences of HST-producing Alternaria spp. were different from those of A. solani and A. brassicicola by about 7% and 3%, respectively. These results suggest that HST-producing Alternaria spp. are evolutionarily very close to non pathogenic A. alternata although they have host-specific pathogenecity.

호산구성 육아종에 병발된 동맥류성 두개골 골낭종 : 증례보고 Case Report

길승배,허철,변진수,한용표,김헌주,홍순기,김명순,홍순원,김윤미 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.9

A case of aneurysmal bone cyst(ABC1 secondary to eosinophilic granuloma of the skull is reported. In the skull the presence of ABC secondary to eosinophilic granuloma is rare. We reviewed the clinicopathological and radiological features of this type of eocinophilic granuloma at the cranium.