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한국 재래 산양에서 Leptospira spp.에 대한 혈청역학적 연구
한동운,권용국,문진산,윤소라,위성환,장환,탁동섭,이태욱,강문일 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.3
Between January 1999 and September 2001, 948 sera (120 from each province except 108 from Chungbuk) from 8 provinces were sampled from Korean goats. All the samples were serologically tested for Leptospira spp. By the microscopic agglutination test against four L. interrogans serovars including canicola, icterohaemorrhagiae, pomona and hardjo, 948 Korean goats were confirmed as 11 seropositives (1.2%) only infected with L. icterohemorrhagiae. All positive sera were collected from Gyeonggi (5), Gangwon (4) and Chungbuk (2). Titration of them were classified as 1:100 of 10 sera except one case with 1:200 from Gyeonggi. It was meaningful that the pathogen in Korean goats was mainly distributed in the northen part of the country. Consequently, the results in the study were confirmed and analyzed the recent status of infection of leptospirosisas zoonotic agentsome in Korean goats.
한국 재래산양에서 Bovine Viral Diarrhea, Bovine Herpesvirus-1, Parainfluenza Type-3 바이러스에 대한 혈청학적 연구
한동운,권용국,문진산,윤소라,위성환,장환,탁동섭,이태욱,강문일 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.3
The 948 goat sera were serologically tested for ten pathogens including bovine viral diarrhea (BVD), bovine herpes virus type-1 (BHV-1) and parainfluenza virus type-3 (PI-3). By viral neutralizaion test, three pathogens including BVD virus, BHV-1, PI-3 were applied for screening each neutralizing antibody and its titration. Among 948 sera, there were 215 seropositives (22.7%) against BVD virus, 25 (2.6%) against BHV-1 virus, and 161 (17.0%) against PI-3 virus, respectively. In the seropositive cases to BVD virus, provincial prevalence of them were recorded as Gyeongnam(30.8%) for the highest one, while as Jeonbuk (15.8%) and Gyeongbuk(l6.7%) relatively for the lower ones. Among them, higher than 1:8 in antibody titration was classified as 74 cases (34.4%) which were suspected the cycle of its infection in their herds. Among the seropositives to BHV-1, it was relatively lower prevalence rate ranging from 1.7% to 6.7% that those of BVD virus and PI-3, but more importantly they were prevailing across the country. Most of the seropositive cases (42.9%) to PI-3 were classified as 1:4-1:16 in titration, but also distributed all around the country. The prevalence in goats varied according to areas (15.8 to 30.8%). Related to the provincial prevalence of three viral agents in Korean goats, it seemed that three viral pathogens would be directly or indirectly involving in various disorders as primary or secondary causative agents resulting in decreased productivity.
서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)
김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2
Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.
( Kwon-seob So ),( Hye-jeong Hwang ) 융합연구학회 2021 융합연구학회지 Vol.5 No.2
This study was conducted to understand the effect of discussion-type online education on the learning effect of 696 people who took the discussion-type learning at K Cyber University. The collected data were analyzed using ANOVA. As a result of the study, the learning effect increased in all items in 2020 compared to 2019. In the analysis by grade level, there was no significant difference in 2019, but in 2020, the Freshman significantly decreased in learning motivation, interaction and cognitive participation, satisfaction, perceived usefulness, and learning achievement. In the analysis by age, in 2019, learning motivation, cognitive participation, perceived usefulness, interaction, and immersion were significantly higher in the age group over 60 years old. In 2020, the motivation for learning was higher in the age group over 60 years old, and in interaction and cognitive participation, under 39 years old and over 60 years old were higher, academic achievement was under 39 years old, and loyalty was under 39 years old and 50-59 years old were higher. As a result, discussion-based learning can be said to be a learning method to improve the learner’s class satisfaction. As a measure to improve learner satisfaction in the future, it is necessary to prepare a basic approach to improve the learning effect for first graders, who have poor learning effects in all items, and to develop various customized learning programs to improve the learning effect by age group.
노인의 경제적 수준에 따른 의료이용이 주관적 건강수준과 행복감 지수 및 삶의 질에 미치는 영향
소권섭(Kwon-Seob So),황혜정(Hye-Jeong Hwang),김은미(Eun-Mi Kim) 한국산학기술학회 2019 한국산학기술학회논문지 Vol.20 No.3
이 연구는 경제적 수준에 따라 노인들의 주관적 건강수준과 행복감 및 삶의 질을 높이기 위한 구체적인 방안을 모색하고 그에 따른 사회적ž정책적 대안을 제시하고자 실시하였다. 연구방법으로는 지역사회건강조사_지표뱅크(2015)_v09를 이용하여 65세 이상 노인 63,929명을 대상으로 경제적 수준에 따른 건강이용 정도가 주관적 건강수준과 행복감 및 삶의 질에 미치는 영향에 대해 빈도분석 및 카이제곱 분석과 독립표본 t-검정을 실시하였으며, 주관적 건강수준을 종속변수로 다중로지스틱 회귀분석을 실시하였으며, 행복감과 삶의 질에 미치는 영향요인을 파악하기 위해서는 다중 선형회귀분석을 실시하였다. 연구결과는 다음과 같다. 수급자의 경우 의료이용은 비수급자에 비해 낮았고, 교육수준이 낮을수록, 여성일 경우, 나이가 75세 이상, 스트레스를 많이 느낄수록 낮은 의료이용을 보였다. 현재 또는 과거 수급자인 경우 미수진 한 결과는 주관적 건강수준이 나쁠수록 증가하였고, 비수급자의 경우 행복감과 삶의 질은 높았다. 결과적으로 수급 대상자의 의료이용에 대한 기회를 늘릴 수 있는 대안이 필요하며, 그 중에서도 여성과 75세 이상 노인에 대한 각별한 사회적 관심이 필요하다. 추후 저소득층 노인인구의 건강증진 및 행복감 및 삶의 질을 효과적으로 향상시킬 수 있는 기초자료로 활용될 것으로 기대된다. The purpose of this study was to find concrete measures to improve the subjective health level, happiness and quality of life of the elderly according to economic level and to propose social and policy alternatives accordingly. As a research method, 63,929 elderly people aged 65 or older were surveyed using the Community Health Survey (Indicator Bank) _v09, and the frequency of health use by economic level, subjective health level, euphoria and quality of life Analysis and Chi square analysis and independent t-test. Multi variate logistic regression analysis was performed with subjective health level as a dependent variable and multiple linear regression analysis was performed to determine the factors affecting euphoria and quality of life. The results of the study are as follows. In the case of recipients, medical use was lower than that of non-recipients, lower education level, female age of 75 years or older, and less stress, In case of present or past recipients, the result of non - receipt increased as the subjective health level was worse, and the non - recipient had higher euphoria and quality of life. As a result, there is a need for alternatives to increase opportunities for medical use among the recipients, with particular attention being paid to women and elderly people over 75 years old. It is expected to be used as a basic data to effectively improve the health promotion, happiness and quality of life of the elderly people of low income group.
Cinnamon extract suppresses experimental colitis through modulation of antigen-presenting cells.
Kwon, Ho-Keun,Hwang, Ji-Sun,Lee, Choong-Gu,So, Jae-Seon,Sahoo, Anupama,Im, Chang-Rok,Jeon, Won Kyung,Ko, Byoung Seob,Lee, Sung Haeng,Park, Zee Yong,Im, Sin-Hyeog WJG Press 2011 WORLD JOURNAL OF GASTROENTEROLOGY Vol.17 No.8
<P>To investigate the anti-inflammatory effects of cinnamon extract and elucidate its mechanisms for targeting the function of antigen presenting cells.</P>
( Jeong-seob Lee ),( Dong-hyeok Kim ),( Jee-min Ha ),( Seung-jik Kwon ),( So-dam Lee ),( Jae-il Yoo ),( Kyu Jam Hwang ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.0
Molecular epidemiology of Mycobacterium tuberculosis has been proved to be an important tool for TB control and surveillance, which provides the understating of the dynamic of disease transmission. In this study, we genotyped a total of 3,458 M. tuberculosis isolates obtained by contact investigations in congregate setting, such as schools, companies, and hospitals etc., from 2015 to 2018 in Korea using spoligotyping and 24-loci MIRU-VNTR. The results of genotyping indicated that 81.9% of the isolates belong to East Asian lineage and Euro-American, Indo-Oceanic, and East-African lineage were 15.4%, 1.8%, and 0.9%. A total of 550 isolates from 217 facilities were associated with outbreak cases (2-15 episodes in a case). Systemic analysis with epidemiological information suggested that 76 cases, including 18 cases of schools, 9 of universities, 16 of companies, 20 of medical centers, 5 of senior centers, 1 of correctional institution, 3 of social centers, and 4 of troops, with multiple TB episodes were related with recent transmission. TB transmission rate of Beijing genotype strain is higher than non-Beijing genotype (P<0.001). TB occurrence in elderly (above 60 old years) is less related to recent transmission compared to other age group (P<0.01). And multiple TB episodes in companies would be occurred through separate infection routes compared to high school setting (P<0.05). Our data showed the current status of TB transmission in Korea. Careful interpretation of molecular epidemiology data would help in contact investigations to proper response.
Yoon, Ji Young,Kwon, Mo Sun,Kang, Jee Hyun,Ahn, Kwang Sung,Kim, So Seob,Kim, Nam-Hyung,Kim, Jin-Hoi,Kim, Teoan,Shim, Hosup Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.2
Human follicle-stimulating hormone (hFSH) is a pituitary glycoprotein that regulates follicular development and ovulation. Clinically, hFSH has been used to induce follicular growth in infertile women. The hormone is composed of heterodimers, including a common ${\alpha}$ subunit among the gonadotropin family and a hormone-specific ${\beta}$ subunit. Since assembly of the heterodimer is a rate-limiting step in the production of functional hFSH, transgenic clone cows carrying a single-chain hFSH transgene may efficiently produce functional hormone. Genes encoding the ${\alpha}$ and ${\beta}$ subunits of hFSH were linked using the C-terminal peptide sequence from the ${\beta}$ subunit of human chorionic gonadotropin. Bovine fetal fibroblasts were transfected with the gene construct, including the goat ${\beta}$-casein promoter and a single-chain hFSH coding sequence. Transfected fibroblasts were transferred into enucleated oocytes, and individual nuclear transfer (NT) embryos developed to the blastocyst stage were analyzed for the transgene by polymerase chain reaction. Seventy eight blastocysts (30.8%) were developed from 259 reconstructed embryos. Among these blastocysts, the hFSH gene was detected in 70.8% (34/48) of the embryos. Subsequent transfer of hFSH-transgenic clone embryos to 31 recipients results in 11 (35.5%) early pregnancies. However, all fetuses were lost before reaching day 180 of gestation. The results from this study demonstrated that bovine NT embryos carrying single-chain hFSH could be produced, and further extensive studies in which NT embryos are transferred to more recipients may give rise to single chain hFSH-transgenic cows for biomedical applications.