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      • 혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

        임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

        Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

      • Multiple Spinal Intradural Schwannomas Combined with Sequestered Lumbar Disc Herniation

        김대용,김진욱,정주호,조재훈 고신대학교 의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

        In this report, we describe a case of multiple intradural schwannomas in the spine combined with a upward sequestered disc herniation at L4-L5. It is often difficult to differentiate this tumor from lumbar disc herniation, especially a sequestered hernia. Gadolinium-enhanced MR images were a useful preoperative examination modality for differentiating these lesions from other diseases. Microscopically, the intradural tumors were successfully removed. The dura maters of the L2 and S1 were opened microsurgically, allowing the nerve fibers involved in the tumor to be identified. The involved fibers were cut around the tumor, and the lesion was resected while the intact nerve fibers were preserved. An upward sequestered lumbar disc herniation at L4-L5 was also successfully removed. Based on histological examination of the resected specimen, the tumors were diagnosed as schwannomas. Microsurgery allowed the tumors to be removed with minimal impairment from cutting of nerve fibers in the each nerve root.

      • 하수에서 분리한 합성세제 분해균의 특성

        정민선,전진경,정영건,이해경,권오진,지원대,김관배 嶺南大學校 環境問題硏究所 1993 環境硏究 Vol.13 No.1

        대구시와 경산시의 하수에서 음이온계 합성세제인 sodium dodecyl sulfate(SDS)와 sodium dodecylbenzene sulfonate(SDBS)를 유일한 탄소원으로 이용하는 균주 289종을 분리하고 이중 합성세제 분해력이 강한, 그람음성 간균으로 운동성인 8균주를 선정하여 그 선정균들의 특성을 조사하였다. 선정균은 40℃ 이상에서는 생육하지 못하였으며 생육 최적 pH는 균주간에 다소 차이가 있었으며 pH 4.0 이하에서는 선정균 모두 생육치 못하였다. 질소원으로는 SDS분해균의 생육에는 potassium nitrate가, SDBS 분해균의 생육에는 soytone이 좋았다. SDS 분해균인 DS-3, 6, 8, 24 및 SDBS 분해균인 BS-7, 8은 세제농도가 5.0% 이상에서도 생육이 가능하였다. 선정균들은 tetracycline에 감수성이 강한 것으로 나타났지만 penicillin에는 강한 내성을 띠는 것으로 나타났고, ??와 ??금속이온은 모든 선정균들의 생육을 억제하는 것으로 나타났다. On purpose to isolate the organisms, which would utilize detergents(sodium dodecyl sulfate, SDS and sodium dodecylbenzene sulfonate, SDBS) as a sole carbon source, from the waste water of Kyungsan and Taegu city 289 strains were isolated. Among them 8 strains, which are gram negative rods with motility and produce strong enzyme to biodegrade the synthetic detergents, were selected. The characteristics of them were investigated as follows, 8 strains were failed to grow above the temperature of 40℃ and below the pH 4.0 even though they have variable optimum pH. Potassium nitrate was very effective for the growth of SDS-biodegradable strains and soytone was effective for the growth of SDBS-biodegradable strains as a sole nitrogen source. Among 8 strains especially DS-3, DS-6, DS-8 and DS-24(SDS-biodegradation strains) and BS-7 and BS-8(SDBS-biodegradation strains) could grow above 5.0% of detergent concentration. All of 8 strains were very sensitive to tetracycline but resistant to penicillin. Selected 8 strains were inhibited by metal ions of ??(0.156mg/㎖) and ??(0.156mg/㎖).

      • 금형 생산시스템의 일정계획 시스템 개발에 관한 연구

        정한일,정대영,박진우 大田大學校 産業技術硏究所 1997 산업기술연구소 論文集 Vol.8 No.2

        The scheduling problem in a die manufacturing system can be classified into the job shop scheduling problem. For some reasons, however, this problem can be viewed as the project scheduling problem with resource constraints and is known as the NP class problem. The reasons are as follows, firstly there are several operations such as machining, assembly and disassembly to be performed at the same time, secondly there are precedence relations among parts and operations, finally the available times of machines are different among them. In addition, it is very hard to obtain a schedule due to the characteristics of the die manufacturing system. In this study, we suggested a scheduling method that can generate a schedule in real-time with considering the characteristics of the die manufacturing system, and hierarchically structured schedule that consists of a high level, a middle level and a low level schedules. And we developed a scheduling system that can support making decision related to manufacturing planning and control, and we implemented the GUI for use's convenience.

      • Dimethylnitrosamine에 의하여 유발된 만성 간 병변에 대한 연구

        정진영,강대영 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.1

        In an attempt to elucidate the pathological effects of phenobarbital on dimethylnitrosamine(DMN) induced chronic hepatic lesions, the present studies in the male Sprague-Dawley rats was undertaken to evaluate the number of dysplastic cells and the average nuclear size of 15, 45, 75 and 105 days after DMN injections. The results were as follows : 1. The liver dysplastic cells were present in the DMN treated group, while they were absent in the control. 2. The liver dysplastic cells in the DMN+phenobarbital treated group were more prominent than those of the DMN treated group. 3. The average nuclear size(0.59 to 0.71cm) of dysplastic cells in the DMN treated group was much larger (1.3 to 1.6cm) than that of the control(0.45 to 0.48cm). 4. The average nuclear size(0.63 to 0.71cm) of dysplastic cells in the DMN+ phenobarbital treated group was much larger than that of the DMN treated group (0.59 to 0.68cm). In summary, the result obtained by the present study indicates dimethylnitrosamine induces liver cell dysplasia. The observation also suggests phenobarbital promoted DMN induced liver cell dysplasia.

      • 관상동맥질환 환자에서 스텐트 시술 후 재협착에 관한 연구

        강진환,권영주,박상호,한대희,이상철,김명구,변정득,최병조,심규혁,온영근,현민수,김성구 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

        Background and aims : In the coronary artery disease, a rate of restenosis was much decreased by placement of coronary stent than when percutaneous transluminal coronary angioplasty has been applied, but there are still important clinical problems of restenosis. There has been many progressive studies about various factors contributed to this restenosis. So, we studied a relation between restenosis after placement of coronary stent in the coronary artery disease and many clinical factors, characteristics of stenotic lesion and procedural factors, and also assessed the restenosis rate of various coronary stents. Methods : Total 58 lesions(46 cases of patients ; man 30, woman 16) were evaluated, which has been performed a follow-up coronary angiography after 6 months (mean 188 days) since coronary stent had been placed. Various stents were implanted and assessed a relation between restenosis and many factors. Results : Of 58 lesions were target stenotic studies, there were 22 of restenotic lesions(37.9%), and the restenosis rate wes statistically significant difference in the relation with diabetes mellitus(p<0.05), group of acute myocardial infarction(p<0.05) among clinical diagnosis of ischemic heart disease(stable angina, unstable angina and acute myocardial infarction) in clinical factors and with high dilation pressure of stent(p<0.05) in procedural factors. When the rate of restenosis was evaluated among implanted stents, it was lowest in the Multilink^(®) stent and highest in the Nir Royal^(®) stent(60%). Conclusion : In this study of restenosis and various factors after placement of stents in the coronary artety disease, factors such as diabetes mellitus, group of acute myocardial infarction and a dilation pressure of stent were significant related with restenosis and the restenosis rate of Multilink^(®) stent was lowest and the highest restenosis rate was of Nir Royal^(®) stent.

      • 치합형 역방향회전(Intermeshing Counter-Rotating) 이축스크류식 압출기내의 등온 비뉴토니언 흐름 분석

        방대석,홍명혁,정영진 國立金烏工科大學校 産業技術開發硏究院 2002 産業技術開發硏究 Vol.18 No.-

        A proper and correct formulation of an isothermal non-Newtonian flow in intermeshing counter-rotating twin screw extruder modules which accounts clearly for the positive pumping displacement mechanism is presented. Screw pumping characteristic curves were determined for various typical elements of the Leistritz modular intermeshing counter-rotating twin screw extruder.

      • SCOPUSKCI등재

        EEMR 관을 이용한 식도 과립세포종의 제거 1예

        문정섭,유권,전영빈,정원종,양대열,이승진 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.4

        The granular cell tumor was first described in 1926. Recently, it has been suggested that the tumor is Schwann cell in origin, and this notion has been supported by electron microscopic studies and immunohistochemistry of the S-100 protein. The most frequently involved organs include the tongue, skin, breast, and digestive tract. The esophagus is rarely involved. The treatment of choice for an esophageal granular cell tumor is still controversial. The traditional treatment has been surgical excision, but new therapeutic options, including laser surgery, diathermy loop, and multiple biopsies have recently been tried. An endoscopic esophageal mucosal resection (EEMR) tube, originally designed for resection of early esophageal cancer, is widely used nowadays. A case of a granular cell tumor of the esophagus, which was successfully removed by an EEMR tube, is herein reported.

      • 주요우울장애 환자와 범불안장애 환자의 성격 특성 비교 연구

        백대업,제영묘,김상엽,이대수,김현진,조정녀,최진혁 대한생물치료정신의학회 2003 생물치료정신의학 Vol.9 No.1

        연구목적: 주요우울장애와 범불안장애는 병발율이 높아 두 질환의 관련성에 관한 연구가 있어 왔다. 본 연구는 성격평가 질문지(Personality Assessment Inventory)를 적용하여 두 환자군에서 성격 특성을 비교해 보고자 하였다. 연구방법: 2001년 8월1일부터 2001년 11월 30일 사이에 종합병원 정신과를 방문한 환자들을 대상으로 하여 전문의의 면담을 통한 진단과 DSM-Ⅳ 진단 기준에 의한 SCID-Ⅰ을 적용하여 최종 진단된 16명의 주요우울장애 환자 및 12명의 범불안장애 환자를 대상으로 성격평가 질문지를 적용하였다. 연구결과: 긍정적 인상척도(positive impression)가 주요우울장애 환자군에서 범불안장애 환자군에 비하여 의미 있게 높았다. 결 론: "남에게 잘 보이려는 경향"이 범불안장애 환자군에 비하여 주요우울장애 환자군에서 많았다. Objectives : The purpose of this study is to compare characteristics of personality in the patients with major depressive disorder and those with generalized anxiety disorder by using the PAI(personality Assessment Inventory) Methods : PAI(Personality Assessment Inventory) was applied to 16 patients with major depressive disorder and 12 patients with generalized anxiety disorder. Results : PIM(positive impression) score was significantly higher in the patients with major depressive disorder than those with generalized anxiety disorder. Conclusion : The patients with major depressive disorder have more "faking good"tendency than those with generalized anxiety disorder.

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