조기 위암의 조직 분화도에 따른 내시경적 육안 소견

김남재,이경태,김진희,송규상,이승민,정현용,김석현,노승무,이병석,조준식 대한소화기내시경학회 2000 Clinical Endoscopy Vol.20 No.2

Background/Aims : The aim of this study was to investigate the endoscopic findings of early gastric cancer according to histological differentiation. Methods : One hundred eight cases of early gastric cancer (EGC) which had been confirmed surgically over a 1 year and 7 month period, were studied to assess the relationship between histological differentiation and endoscopic findings. Results : All elevated types of EGC (41 cases) were found to be differentiated carcinoma. 48.2% (30/67 cases) of the depressed type EGC was determined to be differentiated carcinoma, while the others (51.8%) were undifferentiated carcinoma. Twenty-four of thirty cases with differentiated depressed type EGC showed a reddish discolored surface (80%), and the others manifested a whitish or mixed colored surface of red and white. In the undifferentiated depressed type EGC, 73% (27/37 cases) revealed a whitish or mixed colored surface, while the others (27%) showed a reddish discoloration. In the differentiated depressed type EGC, the character of the depressed surface was mainly regular and soft or fine granular (77%), while that of the undifferentiated cases appeared as uneven large granules (43.2%) or fine granules (43.2%), sclerotic (2.8%) and/or elevated (10.8%). The margin of the depressed type EGC with differentiated carcinoma was mainly of a shoaling beach type (83.3%), and that of the undifferentiated carcinoma was not uniform and existed as a cliff type (60%), Riasis coast type (11.4%) and shoaling beach type (28.6%). Conclusions : All elevated types of EGC showed differentiated types, and histological differentiation of depressed type EGC was macroscopically determined by the size of lesions, color, and character of the depressed surface and margin of the depression.

전통음료 섭취에 영향을 주는 변인에 관한 분석연구

이현주,손경희,이민준 한국조리과학회 2002 한국식품조리과학회지 Vol.18 No.1

This study was conducted to (a) investigate the frequency of Korean beverage consumption, (b) analyze the characteristics of socio-demographically classified group according to drinking frequency, (c) investigate the attitude for and awareness of Korean beverage and (d) analyze the factors which influence Korean beverage consumption. The survey was carried out by self-administered questionnaires with 2,200 subjects residing in Seoul. A total of 1,885 samples were used for analysis by using t-test, one way analysis of variance (ANOVA), Duncan's multiple comparison test, factor analysis, and analysis of covariance (ANOCOVA)with SAS computer program. Among various Korean beverage, Doggulre tea was consumed most frequently at an average of 7.4 times per month, and followed by rice beverage, Mi Su, Citron tea, Shick Hae and canned Shick Hae. Among the age groups, the group of 20s showed the lowest frequency of Korean beverage consumption exempt rice beverage. According to occupation group, middle and high school and college student groups showed a high frequency of consumption of cereal based drink such as rice beverage, Mi Su and Yulmu tea. The behavior examination aimed at learning the perceptions relevant to the choice of beverage showed that the subjects believe Korean beverage healthful and nutritious but not familiar through advertisement, not easy to buy, and not to be a habitual drink. The factors influencing the frequency of Korean beverage consumption were shown as health-related factors and habitual/practical factors.

측두엽 간질에서 F-18-FDG PET에 나타난 측두엽 내외측 부위별 대사의 차이

이명철,이동수,정준기,김현집,송호천,이상건,여정석 대한핵의학회 1999 핵의학 분자영상 Vol.33 No.1

Purpose: We investigated the difference of glucose metabolism of medial and lateral temporal lobes of patients with temporal lobe epilepsy (TLE) utilizing quantitative comparison of regional metabolic activities using asymmetric index. Materials and Methods: We studied 19 pathologically proven mesial TLE and 25 lateral TLE patients. Lateral TLE patients were either normal on magnetic resonance imaging (cryptogenic: n=14) or had structural lesions (lesional: n=11). Asymmetric index (ASI) was calculated as [(ipsilateral-contralateral)/(ipsilateral+ contralateral)]×200. Results: ASI of medial and lateral lobes of mesial TLE was decreased (-16.4±8.3 and -12.7±5.5, respectively). In cryptogenic lateral TLE, ASI of lateral temporal lobe was decreased (-11.8±4.7), whereas that of medial temporal lobe was not decreased (-4.6±6.3). ASI of medial lobe of lesional lateral TLE was -7.3±9.1, which was significantly different from that of mesial TLE (p<0.05). Patients with lesional lateral TLE had evident metabolic d or decrease (ASI: -22±10.5) in lateral temporal lobe. While we could not find the difference of metabolic activity in lateral temporal lobes between cryptogenic lateral TLE and mesial TLE patients, the difference of metabolic activity was significant in medial temporal lobes which was revealed by ASI quantitation. Conclusion: Asymmetric decrease of metabolic activity in both medial and lateral temporal lobes indicates medial temporal epilepsy. Symmetry of metabolic activity in medial temporal lobe combined with asymmetry of that in lateral temporal lobe may give hints that the epileptogenic zone is lateral.

단일방향 섬유 복합재료 내의 초음파 전파 및 산란 현상의 해석과 시뮬레이션

이춘재,임현준 한국비파괴검사학회 2001 한국비파괴검사학회지 Vol.21 No.3

복합재료의 초음파검사는 매질의 탄성이방성으로 인해 빔스큐(beam skew)현상 등이 발생하기 때문에 등방성 재료의 검사에 비해 훨씬 어렵다. 그 동안의 많은 연구의 결과로서 이방성 재료 내 탄성파의 전파 현상에 대한 해석해법이 정립되어 있으나, 그 해석해가 매우 복잡하여 실제 문제의 해를 구하기 위해서는 수치적인 방법에 의존하여야 하는 경우가 많다. 본 연구에서는 횡등방 이방성(transversely isotropic)으로 가정할 수 있는 단일방향 섬유 복합재료 내점원에 의한 초음파 전파의 해석해를 먼저 구하고, 이러한 복합재료를 질량-스프링 모델로 모델링하여 해석해에 상응하는 수치해를 구하였다. 그 결과, 초음파의 전파에 대한 수치해와 해석해가 매우 잘 일치하는 것을 확인하였다. 동일한 수치해법을 사용하여 초음파가 복합재료의 자유표면에서 반사되는 현상과 균열에 의해 산란되는 현상에 대한 수치해도 구하였으며 그 결과를 파동역학의 관점에서 고찰하였다. 본 연구에서 그 유효성이 확인된 수치 모델은 복합재료의 초음파검사를 시뮬레이션 함에 있어 매우 유용하게 사용될 수 있을 것이다. Ultrasonic testing of composite materials is much more difficult than that of isotropic materials, because of the beam skew phenomenon caused by their elastic anisotropy. An established analytical method exists for elastic wave propagation in anisotropic media as a result of previous research efforts. Yet, due to the complexity of the analytical method, solution of real problems must resort to the numerical method. In this work, analytical solutions have first been obtained for the wavefield due to a point source in a unidirectional fiber-reinforced composite, which may be modeled as transversely isotropic. Then, the corresponding numerical solutions have been obtained using the mass-spring lattice model(MSLM). The two solutions have agreed well with each other. Other problems such as reflection from free boundaries and scattering from cracks have also been solved numerically, and the results have been investigated from the viewpoint of wave mechanics. The numerical model whose validity has been confirmed by this work will be of great use in simulating ultrasonic testing of composite materials.

류마티스성 관절염 및 퇴행성 골관절염에 있어서의 Tenoxicam(Tilcotil^(�))제제의 임상적 연구

이준규,임현수,이정웅,김석범 최신의학사 1988 最新醫學 Vol.31 No.6

스마트폰 뱅킹에서 사용하는 보안카드의 안전성 강화방안

이현종, 조인준 배재대학교 공학연구소 2014 공학논문집 Vol.16 No.1

전 세계적으로 스마트폰이 보급되면서 스마트폰을 활용한 여러 가지 서비스가 증가하고 있다. 다양한 앱의 개발 및 소셜 네트워크 서비스 등으로 사용자에게 편리성을 제공하고 있으나, 그 취약점 또한 해결해야할 하나의 과제이다. 그중에서도 스마트폰 뱅킹은 이미 그 가입자수가 상당수에 이름에도 스마트폰 뱅킹 니즈의 부재, 보안문제와 정보 유출 가능성에 대한 우려로 사용을 기피하고 있다. 특히 스마트폰 뱅킹에 사용되는 보안카드는 사용자의 편의를 위해 메모나 사진으로 저장하여 사용하고 있는 실정이며 이는 해킹에 의해 그대로 노출될 수 밖에 없다. 스마트폰 뱅킹은 스마트폰으로 플랫폼은 변경되었으나 인증방식은 기존의 PC 기반의 인터넷 뱅킹 인증방식을 도입하여 취약점을 그대로 갖고 있다. 특히 보안카드와 관련한 보안방식은 미흡한 실정이다. 본 논문에서는 스마트폰 환경에서 안전하게 보안카드를 사용할 수 있는 방안을 제시한다. 제안한 방안은 패스워드 기반의 암호화로 시스템에 접속시마다 키값이 변경되어 보안카드를 암호화하므로 보안의 강도를 높였고 노출의 우려가 없다.

류마티스성 관절염 및 퇴행성 골관절염에 있어서의 Tenoxicam ^� 제제의 임상적 연구

이준규,임현수,이정웅,김석범 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.1

The authors have conducted a clinical study to evaluate the efficacy, tolerance and safety with newly developed Tenoxicam^ⓡ to thirty-four cases of the patient of Rheumatoid arthritis and Degenerative osteoarthritis during 4 months from January 1988 to April 1988. Treatment for the patient was done with one tablet of Tenoxicam^ⓡ (20mg) per oral once a day for 4 weeks. The evaluation of the patient was done at second and fourth week after initial administration of the drug. Results were as follows: 1. Out of 34 cases, male were 4(11.8%), female were 30(88.2%), and predominent age group was 40-59 years old 17(50.0%). 2. The diagnosis of these patients were Rheumatoid arthritis 22(64. 7%) and Degenerative osteoarthritis 12(35.3%). 3. Overall efficacy, there was marked improvement in global condition, pain on movement, pain at night and stiffness. 4. Side effects were seen in 4 patients such as 2 case of heartburn, 1 case of nausea and vomiting and 1 case of diarrhea. 5. There were no significant difference between pre-and post-treatment laboratory check. 6. Conclusion: The oral Tenoxicam^ⓡ was very effective for the treatment of Rheumatoid arthritis and Degenerative osteoarthritis, and side effects were few and generally mild.

위암 환자의 복강내 투여를 위한 Activated Charcoal-Alginate Bead 제형으로부터 Mitomycin C의 용출 거동

이진호,최선웅,서중기,김동민,정경수,오정연,김진향,노승무,민병무,김용백,김창식,박근성,강대영,송규상,양준묵,조준식,정현용,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherapy seems a logical choice for cancer chemotherapy. In this study, Mitomycin C (MMC)-activated charcoal (CH)-alginate (ALG) beads were prepared by the mixtures of CH particles adsorbed with MMC as an anti-cancer drug and aqueous alginate solution. The alginate is recognized as biodegradable, nontoxic, and biocompatible. The release of MMC from the beads in 0.1 M Tris buffer was stable and continuous until about 1 week. The MMC-CH-ALG beads can be applied in the peritoneal cavity for intraperitoneal chemotherapy since they provide a good adhesiveness on the tissue and controlled release pattern of the drugs.

전통음료 인지도에 관련된 제요인 분석

이현주,손경희,이민준 한국식생활문화학회 2001 韓國食生活文化學會誌 Vol.16 No.5

Traditional Korean beverage can be divided into Jang, Gahl Soo, Mi Su, Mil Su, Soo Jung Gwa, Shick Hae, Tahng, Hwa Chae, Sook Su, and Tea according to ingredients and how it is proccessed. The purpose of this study was to investigate the Korean beverage percetpion and to analyze the factors(sociodemographic factors and life-style related factors) which influence percetpion of Korean beverage. Questionnaries were hand delivered to 2,200 subject residing in Seoul and 1,884 questionnaris were collected : resulting in 84% response rate. Statistical data analysis was completed using SAS Package program for the analysis of covariance(ANOCOVA). The results are as follows: (a) Survey on Korean beverage perception showed that the recognition rates of Shick Hae(58.4%), Cition Tea(53.5%), Sung Nung(48.7%) and Soo Jung Gwa(40.8%) were high, whereas those for Tahng, Jang, and Gahl Soo were low. (b) About 40% of respondents performing 4 kinds of Korean traditional ceremony a year. The percentage that reported they purchased Korean beverages was 44.0%, higher than the 38.5% that answered they made Korean beverage at home. (c) In analyzing the factors which influence beverage perception, the sociodemographic factors variously influenced perception rate depending on beverage. Age and sex had influenced on perception rate of Shick Hae and Donggulre Tea. Income level influenced on the perception rate of Sung Nung and Citron Tea. Sociodemograhpic factors like senior over 50s, female and extended family size had positive influence on the perception rate

만성 B형 간염 환자의 급성 악화 후 발생한 피부 결절 다발동맥염과 류마티스관절염

이주현,김민,이준성,장선희,윤보영,이윤우 인제대학교 2009 仁濟醫學 Vol.30 No.-

Cutaneous polyarteritis nodosa(CPAN) is a rare vascular disorder that affects small and medium-sized arteries in the reticular dermis and subcutaneous tissue. It has been described as a distinct clinical entity with benign and a chronic prolonged course without systemic involvement. Hepatitis B virus-related polyarteritis nodosa (HBV-related PAN) is typical form of classic PAN. Its pathogenesis is not well known, but considered an immune complex-mediated disease. The patients with HBV-related PAN often present with malignant hypertension, orchitis, and vascular nephropathy. But, HBV-related CPAN has been rarely reported. Rheumatoid vasculitis is a complication of rheumatoid arthritis that can be lead to variety of clinically significant skin and systemic conditions, It has been reported before or at the time of rheumatoid arthritis diagnosis but is usually seen an average of 10 to 14 years after arthritis onset. The histological features of cutaneous vasculitis in rheumatoid arthritis overlapped both the characteristics of cutaneous necrotizing venulitis and cutaneous polyarteritis nodosa. But polyarteritis nodosa-like rheumatoid vasculitis has rarely been reported. We report a case of rheumatoid arthritis and cutaneous polyarteritis nodosa in a chronic hepatitis B with acute exacerbation.