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      • 혈관내피성장인자에 관한 고찰

        김석범,김동현,송주영,김진상,Kim, Souk-Boum,Kim, Dong-Hyun,Song, Ju-Young,Kim, Jin-Sang 대한물리치료학회 2002 대한물리치료학회지 Vol.14 No.1

        Vascular endothelial growth factors(VEGFs) constitute a group of structurally and functionally related growth factor that modulate many important physiological functions of endothelial cells, especially angiogenesis. This paper explain substance, which participate in signaling transduction of VEGF, including Bcl-2, caspase, focal adhesion kinase(FAK), integrin ${\alpha}v{\beta}3$, MAP kinase, nitric oxide(NO)and prostacyclin(PGI2). Physical therapy enhance angiogenesis for repairment of injury which as wound healing, muscle contusion, cerebrovascular disease, rheumatoid arthritis. Therefore this review assist understanding for mechanism of physical therapy as therapeutic angiogenesis.

      • KCI등재

        국립공원 내 도 로에서 뱀 류 로 드킬 현황

        김석범,이정현,박대식 한국하천호수학회 2018 생태와 환경 Vol.51 No.3

        The roadkill that animals die after bumping by vehicles on the roads is acting as a factor to decrease the size of various animal populations. It has also been known to be the biggest artificial causations of Vertebrata deaths not only in urban areas but also protected areas such as national parks. Nevertheless, in the national park areas which are major protected national areas for conservation of national biodiversity and ecological diversity, snake roadkills occur frequently. Up to date, related studies are rare. Therefore, in this study, we described snake roadkill patterns on the roads in six national parks between 2006 and 2015. We identified total 736 snake roadkills compromising 10 different species. Five species, Rhabdophis lateralis, Elaphe dione, Gloydius ussuriensis, Lycodon rufozonatus, Gloydius brevicaudus occupied more than 91.7% of total roadkill cases. Active forager snakes were killed by roadkills more than ambush foragers, and the snake roadkill frequency was the highest in September, a migration period and in August when the young individuals dispersed at between 100 and 799 m altitude areas. Roads where roadkills were frequent lie between forest and hydrosphere or between forest and crop field road sides. Our results could be used to identify the trend of snake roadkills on the roads in national parks, and to establish effective roadkill mitigation measures and policies.

      • 저강도레이저 조사가 근육압좌손상 후 척수분절의 EGF 발현에 미치는 영향

        김석범,김동현,남기원,이선민,김진상,Kim Souk-Boum,Kim Dong-Hyun,Nam Ki-Won,Lee Sun-Min,Kim Jin-Sang 대한물리치료학회 2002 대한물리치료학회지 Vol.14 No.2

        Low energy laser irradiation(LELI) therapy in physical therapy is widespread but the mechanisms are not fully understood. The purpose of the present study was to examine the epidermal growth factor(EGF)'s expression within lumbar spinal cord which corresponding with crushed extensor digitorum longus(EDL) of rats after low-power laser irradiation applied. After a crushed injury on the right EDL, low-power laser irradiation was applied by using 2000mW, 2000Hz, 830nm GaAlAs(Gallium-aluminum-arsenide) semiconductor diode laser. The laser treatment was performed with 10 minutes daily for 3days. After EDL crush injury, EGF immunoreactive positive neurons in experimental group were progressively decreased from the first to third days. Especially 1 day subgroup is highly expressed in dorsal horn(Lamina I, II, III) and around of central cannal of spinal cord(Lamina VII). Control group was only expressed slightly at 3 days. This study suggests that LELI stimulate that release and migration of EGF in spinal cord, which distict to wound site, therfore promote wound healing of EDL crush injury.

      • KCI등재
      • 마이크로파를 이용한 SHS 방법에 의한 분말의 산화-환원반응

        김석범 한국결정학회 1998 韓國結晶學會誌 Vol.9 No.1

        가정용 2.45GHz 마이크로파 오븐을 사용하여 A1 금속분말과 SiO2 분말간에 SHS방법에 의하여 산화/환원 반응을 통한 Al2O3 분말과 Si분말간의 복합체를 얻을 수 있었다. 분말간의 반응을 일으키기 위한 온도까지 승온시키기 위하여는 SiC 분말을 susceptor로 이용한 마이크로파 복합가열(Microwave Hybrid Heating)방법을 사용하여 분당 100℃의 승온 속도로 가열하였으며 반응은 850℃ 근처에서 일어났으며 가열 속도는 반응이 시작되면서 분당 200℃ 이상의 온도상승이 일어나면서 원하는 반응을 얻을 수 있었다. A reduction/oxidation reaction between A1 metal powder and SiO2 powder was performed by Self-propagating High-temperature Synthesis (SHS) reaction induced by microwave energy to produce a composite of Al2O3 and Si powders by using a 2.45 GHz kitchen model microwave oven. A Microwave Hybrid Heating(MHH) method was applied by using SiC powders as a suscepting material to raise the temperature of the disk samples and the heat increase rate of over 100℃/min were obtained before the reaction. The reaction started around 850℃ and the heat increase rate jumped to over 200℃/min after the reaction took place.

      • KCI등재

        3D Printed Fluidic Valves for Remote Operation via External Magnetic Field

        김석범,이정철,최범규 한국정밀공학회 2016 International Journal of Precision Engineering and Vol.17 No.7

        This paper reports a novel 3D-printed fluidic valve which is fabricated by projection-stereolithography (PSL) in combination with insertion of functional elements such as permanent magnets. We first constructed a PSL setup which can fabricate complicated three dimensional structures via layer-by-layer photocuring. Then, 3D fluidic valves which could be remotely controlled were designed. After the working mechanisms of proposed fluidic valves were thoroughly analyzed, they were fabricated with outlet orifice diameters of 0.5, 1, and 2 mm. The main housing of the valve assembly was printed, then, three permanent magnets were inserted into the part and the valve fabrication was completed by combining the end cap with an orifice and sealing. The completed valve was integrated within a 20-Fr (6.7-mm in diameter) medical catheter for evaluation. The flow rate through the valve could be controlled by changing positions of the inserted permanent magnets with an external magnetic field. With the applied pressure of 10 kPa, the flow rate was measured to be 131.07 mL/min that is only 8.78% lower than the system without the valve (143.68 mL/min). The results obtained in this work would be beneficial to further development of efficient fluidic valves for complicated 3D fluidic systems.

      • KCI등재

        석탄회가 첨가된 점토의 마이크로파를 이용한 소결

        김석범,한정환,김유택 한국결정성장학회 1998 韓國結晶成長學會誌 Vol.8 No.3

        석탄회의 점노를 70:30의 비율로 혼합하여 마이크로파를 이용하여 소결하였으며, 소결에는 2.45Ghz의 일반가정용 마이크로파 오븐을 사용하였다. 시편은 $1,150^{\circ}C$에서 50분까지 10분 간격으로 소결하였다. 석탄회의 미세구조는 주사전자현미경(SEM)과 Energy dispersive spectrometry(EDS)를 이용하여 분석을 하였으며 X선회절 분석과 압축강도와 겉보기 비중을 추정하여 비교하였으며 시간이 지날수록 시편의 기공크기는 작아졌으나 압축강도와 겉보기 비중은 변화의 크기가 작았다. 로안에서의 마이크로파에 의한 시편으로의 열전달현상을 알아보기 위하여 컴퓨터를 이용한 수치해석을 행하였다. Fly ashes mixed with clay as 70:30 weight percent were sintered by microwave energy and a 2.45 Ghz kitchen model microwave oven was used. Samples were sintered at $1,150^{\circ}C$ and kept at that temperature up to 50 minutes by 10 minutes intervals. Microstructures were taken by Scanning Electron Microscope (SEM) and Energy Dispersive Spectrometry (EDS) analysis of a raw fly ash was taken. X-ray diffraction analysis was done, and compressive strengths and apparent densities were measured. Pore sizes of the samples became smaller as time passed by, but compressive strengths and apparent densities did not change much. Numerical analysis on the microwave heated system was carried out in order to figure out heat transfer phenomena in the cavity.

      • KCI등재

        학교문화예술교육 현황 및 개선방안 연구 -영화교육을 중심으로-

        김석범 한국영상제작기술학회 2018 영상기술연구 Vol.- No.29

        In the era of the Fourth Industrial Revolution, human creativity became more important than any other element. As the functions and roles of arts and culture education gradually increase as a national growth engine in response to the rapidly changing demands of the times, the government begins full-scale arts and culture education throughout the country with the aim of cultivating creative talents. Especially, as the arts and culture education is carried out in the school which is the public education field, it has a positive educational effect that can not be obtained from the traditional education. In particular, arts and culture education, which is distinguished from traditional art education, has achieved a little visible result through rapid growth in a long time. However, arts and culture education in school, which started as part of the national policy project, shows clear limitations and problems in terms of quality despite the rapid growth in quantitative support. In this study, we will discuss the problems and improvement plans of arts and culture education in school over the past 10 years based on the current status of film education.

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