조혈모세포이식 환자에서 발생한 Cytomegalovirus 질환의 특징 : 일개 대학변원에서 최근 10년간의 경험

최수미,이동건,박선희,김시현,김유진,민창기,김희제,이석,최정현,유진홍,김동욱,이종욱,민우성,신완식,김춘추 대한감염학회 2009 감염과 화학요법 Vol.41 No.1

Background : Studies on cytomegalovirus (CMV) diseases in Korean hematopoietic stem cell transplant (HSCT) recipients are lacking and do not reflect the recent trends of advances and changes. Therefore, we tried to analyze the clinical features of CMV diseases in HSCT recipients over the past 10 years at a tertiary university hospital in Korea. Methods : Retrospective review of medical records was done for all adult HSCT patients who received transplant at the Catholic HSCT Center from January 1998 to January 2008. Results : Forty-four cases (2.2%) of CMV diseases were identified. CMV pneumonia was diagnosed in 17 patients, retinitis in 16 patients, enterocolitis in 7 patients, esophagitis 1 patient, gastritis in 1 patient, duodenitis in 1 patient, and hepatitis in 1 patient. The median onset of symptom was 90 days after transplantation. Late CMV diseases accounted for 47.7%. CMV related death varied from 0 to 58.8% according to the involved organ. CMV retinitis was diagnosed relatively later in the course of transplantation mostly in patients who had chronic graft versus host disease (GVHD). On the contrary, CMV enterocolitis mainly occurred in patients who suffered from acute GVHD. The overall concurrent CMV reactivation was documented to be 63.6%: the concurrent CMV reactivation was observed only in 37.5% of patients with retinitis. Conclusions : We observed some differences in the pattern of CMV disease manifestation according to the involved organ and reconfirmed the fact that CMV pneumonia is the most common and fatal disease in HSCT recipients. Additionally, CMV retinitis was not uncommon in HSCT recipients. Since specific marker does not exist in predicting retinitis, regular ocular examination should be done thoroughly, especially in patients with chronic GVHD.

韓國河川의 流出率과 流出指標로서의 洪水直前 流量

金熙鍾,柳又秀,金佳鉉,申東守,韓健模,全裕燦 東亞大學校 大學院 1984 大學院論文集 Vol.9 No.-

This paper is a study on relation between run-off ratio and antecedent discharge, run-off ratio and antecedent discharge per unit area, antecedent discharge and antecedent precipitation, by the data from the five major river basins in Korea and the small river basins in Pusan. The Nak-Dong rivers(An-Dong upper stream) f=0.4780+0.0124 ln qA r=0.99 qA=0.3368e0.1101R r=0.99 f=0.5793+0.0146 ln(qA/A) r=0.99 The Nak-Dong rivers except Ga-song station f=0.2017-0.0840 ln qA r=0.75 f=0.7012+0.0750 ln(aA/A) r=0.71 The Han rivers f=-0.0035+01267 on qA r=0.75 f=1.1311+0.1263 ln(qA/A) r=0.71 L=302.9064-43.8490 ln qA r=0.84 The Geun rivers(Mu-sin Cheon) f=0.295+0.1823 ln qA r=0.93 f=0.8417+0.1823 ln(qA/A) r=0.93 L=40.0456+62.0346 ln qA r=0.94 The Yeong-san rivers f=0.3766+0.0598 ln qA r=0.79 f=0.8084+0.0599 ln(qA/A) r=0.79 The Seom-jin rivers f=-1.3875+0.6505 ln qA r=0.92 f=2.1633+0.3465 ln(qA/A) r=0.76 Small river basin in Pusan f=0.3635+0.1120 ln qA r=0.87

동강의 어류상과 생태학적 군집분석

최준길 ( Jun Kil Choi ),오사무미타무라 ( Osamu Mitamura ),이동준 ( Dong Jun Lee ),신현선 ( Hyun Seon Shin ) 한국환경생태학회 2008 한국환경생태학회지 Vol.22 No.6

2006년 5월부터 2007년 5월까지 동강의 어류상과 생태학적 군집분석을 조사한 결과는 다음과 같다. 조사된 어종은 총 10과 31종이었다. 총 31종의 어종 중 일차담수어가 26종, 주연성 담수어가 5종으로 나타나 일차담수어의 구성비가 매우 높았다. 우점종은 참갈겨니(Zacco koreanus) 55.73%, 아우점종은 쉬리(Coreoleuciscus splendidus) 7.15%였으며, 우세종은 배가시리(Microphysogobio longidorsalis) 6.12%, 어름치(Hemibarbus mylodon) 4.87%, 참종개(Iksookimia koreensis) 4.49% 등이었다. 한국고유종은 묵납자루(Acheilognathus signifer), 줄납자루(A. yamatsutae), 가는돌고기(Pseudopungtungia tenuicorpus), 쉬리(C. splendidus), 긴몰개(Squalidus gracilis majimae) 그리고 어름치(H. mylodon) 등 19종(61.29%)으로 고유종의 빈도가 매우 높았으며, 천연기념물이 1종, 환경부지정 멸종위기 야생동물 II급 종이 5종으로 각각 확인되었다. 예상되는 종수(기대종)의 분석 결과, 동강의 전 조사지점에서는 18(지점 4, 5)∼22종(지점 3)이 서식하고 있을 것으로 나타났으며, 유사도 분석은 62.28%(지점 1과 2)∼84.13%(지점 1과 5)의 범위로 나타났다. 따라서 동강유역은 어류가 서식하기에 매우 적합한 수환경을 유지하고 있으며, 각 조사지점별 수환경도 매우 유사한 것으로 판단된다. The ichthyofauna and ecological community analysis in the Dong River, Korea, were investigated from May, 2006 to May, 2007. During the surveyed period, 31 species belonging 9 families were collected. Total of 31 species(primary freshwater: 26 species, peripheral freshwater: 5 species) were found with the primary freshwater fishes being highest. Dominant species was Zacco koreanus(55.73%), and subdominant species was Coreoleuciscus splendidus(7.15%). Also, Microphysogobio longidorsalis (6.12%), Hemibarbus mylodon(4.87%), Iksookimia koreensis(4.49%) were numerous. There were 19 Korean endemic species(61.29%), including Acheilognathus signifer, A. yamatsutae, Pseudopungtungia tenuicorpus, C. splendidus, Squalidus gracilis majimae, H. mylodon. Among them, 1 species was identified as qualifying for possible desigantion as a natural monument catergory, and 5 species were identified for designation required to protect under a wildlife category. As result of expected number of species according to rarefaction curve, the expected species of the Dong-river ranged from 19(St. 4, 5) to 22(St. 3) and result of similarity analysis ranged from 62.28%(St. 1 and 2) to 84.13%(St. 1 and 5). In conclusions, we could define that the Dong-river has a very good water conditions as habitat of fish, and habitat conditions also are very similar in every survey sites.

한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

하수 방류수 살균소독을 위한 무전극 UV Lamp의 개발

신동호,이규현,이용택 한국공업화학회 2003 응용화학 Vol.7 No.2

하수방류수 살균소독에 이용되는 UV 램프를 기존의 전극용보다 효율을 높이고 수명이 긴 무전극 UV 램프를 제작하고 그 성능을 알아보았다. 우선 활성물질을 변화시키면서 제조한 램프의 UV강도 및 온도의 변화를 살펴보았다. 그 결과 활성물질이 Hg/Ind의 무게비 95/5로 만든 램프를 250분간 운전한 결과 UV 강도 300 mW/㎤ 및 표면온도 200-250 ℃로 가장 안정적인 결과를 가져왔다. 그러나 무전극 램프를 장시간 발광시켰을 경우 램프의 표면온도가 상승하기 때문에 실제 하수처리공정에 사용하기 위하여 냉각이 가능한 이중관 형태로 제작하여 UV강도와 온도 변화특성도 알아보았다. 또한 제작된 무전극 UV lamp를 하수 방류수의 살균소독을 위하여 대장균(E-coli.)으로 실험한 결과 99.9% 이상의 살균효율을 보였다.

전방 십자인대의 파열시의 자기공명영상:직접소견의 중요성

신현준,이창희,최영칠,전혜정,박정희,김동헌 건국대학교 의과학연구소 2001 건국의과학학술지 Vol.11 No.-

It is Important to know the normal size, shape, and signal intensity of anterior cruciate ligament in the evaluation of knee injury Many studies have reported findings of tear or rupture as well as normal anatomy of these structure, especially with MR images. To our knowledge, there are few studies about normal structures of anterior cruciate ligament in MR images. The purpose of this study is to compare normal finding with tear of anterior cruciate ligament on MRI. Twenty-three cases with rupture of anterior cruciate ligament were evaluated on MRI, measuring the length, thickness, width of anterior cruciate ligament, and angles of anterior and posterior cruciate ligaments. Mean length, thickness, and width of anterior cruciate ligament in patients with rupture were 37.7±4.8mm, 9.0±1.2mm, 8.0±0.8mm, and mean angles of anterior cruciate ligament, and posterior cruciate ligament were 48.1±9.6˚, 118.8±13.1˚. Curvature ratio of posterior cruciate ligament was 0.25±0.09. The results showed significant differences between normal persons and patients with complete or partial rupture, and the mean angle and curvature ratio of posterior cruciate ligament which are known to related with indirect sign in tear of anterior cruciate ligament showed significant differences between ours and that of western countries. These results will be useful in the evaluation of patient wish rupture of anterior cruciate ligament, especially on MRI.

경남지역 주요 약용작물의 해충 종류 조사

신현열,이동운,추호렬,정도철 경상대학교 농업생명과학연구원 2002 농업생명과학연구 Vol.36 No.4

경남지역 주요 약용 작물 5종에 발생하는 해충과 기타 해로운 동물의 종류를 1999년과 2000년 2개년 동안 조사하였다. 홍화에서는 우엉수염진딧물과 꽃노랑총채벌레, 대만총채벌레, 오이총채벌레, 알락수염노린재를 포함한 13과 16속 20종이 확인되었으며, 산약에서는 꽃노랑총채벌레, 대만총채벌레, 애긴노린재를 포함한 6과 7속 10종이, 두충에서는 차주머니나방을 포함하여 6과 8속 8종이, 당귀에서는 대만총채벌레, 꽃노랑총채벌레, 차응애, 점박이응애, 복숭아혹진딧물을 포함한 11과 15속 16종이, 길경에서는 담배거세미나방, 파밤나방을 포함하여 10과 11속 14종의 해충이 확인되었다. Insect pests and some important arthropod pests infesting five medicinal crops were surveyed in Gyeongnam province in 1999 and 2000. Nineteen species of 16 genera in 12 families including Vroleucon gobonis, Frankliniella occidentalis, F. intonsa, Tetranychus cinnabarinus, Thrips parmi, and Dolycoris baccarum were identified from safflower. Ten species of 7 genera in 6 families including F. occidentalis, F. intonsa, and Nysius plebejus from yam, 8 species of 8 genera in 6 families including Eumeta minuscula from hardy rubber-tree, 16 species of 14 genera in 11 families including F. occidentalis, F. intonsa, T. kanzawai, T. urticae and Myzus persicae from Angelica gigas, 15 species of 14 genera in 11 families including Spodoptera exigua, and S. litura from balloon flower.

Benzene에 의해 오염된 물의 鹽素處理에 의한 鹽素化合物의 生成에 關한 硏究

신현진,최고열,장향동 서울産業大學校 1996 논문집 Vol.44 No.1

This paper describes the production of the second pollution materials possibly produced during the water purification of water contaminated by various inorganic compounds. The effect of the reaction conditions such as the concentration of benzene and remaining chloride, temperature, pH as well as the addition of heavy metal on the production of chlorobenzenes has been investigated. It was confirmed from the results of quantitative and qualitative analyses of products that mono- and dichlorobenzenes, which smelled offensively and were harmful to human body, were created by chlorination of benzene containing water. The production of chlorobenzene was always observed when the concentration of benzene and remaining chloride was higher than 0.1 mg/ℓand 1 mg/ℓ, respectively. The amount of chlorobenzene increased with the reaction temperature and the concentration of reactants. The production of dichlorobenzene was largely dependent on the reaction temperature and the pH of reactant. When the pH of reactant was 2, an appreciable amount of 1.4-dichlorobenzene was produced. However, it decreased rapidly with the pH of reactant and completely disappeared at pH 4. There was no chlorobenzene produced at higher than pH 10. The concentration of chlorobenzene increased by the addition of Al and Fe.

광섬유 집합체 센서를 이용한 6MV 광자선의 반음영 및 심부선량백분율 측정

신상훈,장경원,조동현,유욱재,서정기,이봉수,문주현,박병기 제주대학교 방사선응용과학연구소 2008 방사선응용과학연구소논문집 Vol.22 No.-

In this study, a fiber-optic bundle sensor has been developed using water-equivalent organic scintillating fibers for photon beam measurement. Beam penumbra and percent depth doses(PDD) are measured according to the depth of the photon beam. This sensor has many advantages such as high resolution, real-time measurement and ease of calibration over conventional radiation measurement devices.

고혈압 환자에서 Leukoaraiosis 정도와 망막증과의 연관성 : 예비연구 Preliminary Results

신동익,한현정,서대희,이광훈 關東大學校 醫科大學 醫科學硏究所 2002 關東醫大學術誌 Vol.6 No.1

Changes in the cerebral white matter (leukoaraiosis;LA) are detected with increasing frequency by computed tomography (CT) and magnetic resonance imaging (MRI) in elderly patients with diabetes mellitus and hypertension. The purpose of this study is to determine whether the severity of retinopathy is correlated with degree of LA in patients with hypertension. Twenty-three consecutive patients with patients with hypertension admitted in the department of neurology were evaluated for degree of LA and severity of retinopathy. 8patients were 15female. The age distribution was between 52 and 85 years(mean 69.1years). The duration of hypertension was between 1 and 30 years(mean8.2 years). The degree of LA was correlated with severity of hypertensive retinopathy(p<0.05), especially in relatively young patient, short periods of disease, and female paitents(p<0.05). We can make a rough estimation of degree of LA with fundus examination without CT or MRI evaluations in hypertensive patients, especially in relatively young and female patients with short durations of disease. However, more broad study should be made for these value and relationship.