Inflammatory Monocytes Infiltrate the Spiral Ligament and Migrate to the Basilar Membrane After Noise Exposure

신승호,유지은,정진세,최재영,배승훈 대한이비인후과학회 2022 Clinical and Experimental Otorhinolaryngology Vol.15 No.2

Objectives. Noise exposure leads to an increase in the macrophage population. This increment is thought to be caused by the transformation of infiltrated monocytes into macrophages rather than by proliferation of the cochlear resident macrophages. However, studies on infiltrated monocytes in the cochlea are scarce. Thus, we aimed to investigate the infiltration of monocytes and their transformation into macrophages after noise exposure. Methods. In wild-type and CX3CR1+/GFP C57/B6 mice, inflammatory monocytes were identified by immunofluorescence of mouse cochlear cells. The findings were confirmed and quantitated by flow cytometry. Results. One day after noise exposure, monocytes were identified in the spiral ligament. Flow cytometric analysis confirmed that the monocyte population peaked on post-noise exposure day 1 and decreased thereafter. On day 3 after noise exposure, amoeboid-type macrophages increased in the crista basilaris, and on day 5, they spread to the basilar membrane. Conclusion. Infiltrated monocytes were successfully observed 1 day after noise exposure, preceding the increase in the macrophage population. This finding supports the proposal that infiltrated monocytes transform into macrophages.

복강경 결직장암 수술 후 조기 항암치료의 안전성에 관한 실험군: 대조군 비교연구

신승호,이선일,최동진,우시욱,김진,민병욱,문홍영,김선한 대한대장항문학회 2009 Annals of Coloproctolgy Vol.25 No.6

Purpose: Since micrometastasis is generally inhibited by primary cancer, surgical ablation of the tumor may stimulate the growth of residual cancer cells, if they exist. This supports the importance of early administration of postoperative chemotherapy. Methods: We reviewed the cases of patients who underwent a laparoscopic resection and then received chemotherapy (5 fluorouracil+leucovorin or FOLFOX4) between September 2006 and May 2008. The chemotherapy was scheduled on the 7th or the 8th postoperative day, but was postponed when a final pathologic report was delayed or patients were discharged early. The safety of chemotherapy was evaluated in two ways. Early safety, such as the presence of surgical complications and medical toxicity, was prospectively assessed just before the beginning of the second cycle of chemotherapy. Late safety, such as medical toxicity, was retrospectively estimated from the 2nd to the last cycle. These safeties were compared between the two groups: the early chemotherapy group (n=50) for which chemotherapy started on the 7th or 8th postoperative day as scheduled and the delayed chemotherapy group (n=31) for which chemotherapy started after the 14th postoperative day. Results: Patient demographics were not different between the two groups. With regards to early safety, no differences in surgical complications existed between the two groups. In medical toxicities, there were no differences, except for a higher rate of nausea in the early chemotherapy group (20 percent vs. 10 percent, P=0.01). With regards to late safety, the two groups were not different in the development of medical toxicities. Conclusion: Because nausea is an easily controllable toxicity, we conclude that chemotherapy is safely started on the 7th or the 8th day after a laparoscopic colorectal cancer resection. Purpose: Since micrometastasis is generally inhibited by primary cancer, surgical ablation of the tumor may stimulate the growth of residual cancer cells, if they exist. This supports the importance of early administration of postoperative chemotherapy. Methods: We reviewed the cases of patients who underwent a laparoscopic resection and then received chemotherapy (5 fluorouracil+leucovorin or FOLFOX4) between September 2006 and May 2008. The chemotherapy was scheduled on the 7th or the 8th postoperative day, but was postponed when a final pathologic report was delayed or patients were discharged early. The safety of chemotherapy was evaluated in two ways. Early safety, such as the presence of surgical complications and medical toxicity, was prospectively assessed just before the beginning of the second cycle of chemotherapy. Late safety, such as medical toxicity, was retrospectively estimated from the 2nd to the last cycle. These safeties were compared between the two groups: the early chemotherapy group (n=50) for which chemotherapy started on the 7th or 8th postoperative day as scheduled and the delayed chemotherapy group (n=31) for which chemotherapy started after the 14th postoperative day. Results: Patient demographics were not different between the two groups. With regards to early safety, no differences in surgical complications existed between the two groups. In medical toxicities, there were no differences, except for a higher rate of nausea in the early chemotherapy group (20 percent vs. 10 percent, P=0.01). With regards to late safety, the two groups were not different in the development of medical toxicities. Conclusion: Because nausea is an easily controllable toxicity, we conclude that chemotherapy is safely started on the 7th or the 8th day after a laparoscopic colorectal cancer resection.

XML 문서의 효율적인 구조 검색을 위한 동적 색인 모델

신승호,손충범,유재수 충북대학교 컴퓨터정보통신 연구소 2001 컴퓨터정보통신연구 Vol.9 No.2

XML문서는 정보 표현의 기본 단위인 엘리먼트로 구성되어져 있다. 이러한 정보 표현의 기본 단위인 엘리먼트가 XML문서 내에서 구조 변정 이 발생 할 경우 보다 빠른 검색을 위해 기존의 색인 구조 정보의 변경 없이 효율적으로 처리 되어져야 한다. 이를 위해 본 논문에서는 XML 문서의 구조 변정 시 기존의 색인 구조에 효을적으로 수용될 수 있는 동적 색인 모뗄을 제안한다. 본 논문에서 제안 하는 동적 색인 모뗄을 위한 구조정보는 기존의 EID(Element Id), ETID(Element TrPe Id), SORD(Sibling ORDer) SSORD(Same Sibling ORDer), Ccount 구조정보 추출 방법에 SSORD를 대신한 STSOL(Same TyPe Sibling ORDer List). Scount (STSOL내의 SORD 개수). 그리고 COL(Child ORDer List)을 추가함으로써 구성된다. 이러한 구조정보를 이용해 효율적인 검색을 지원하기 위한 동적 색인 구성 알고리즘을 기술하고 제한하는 색인 기법이 기존의 동적 색인을 지원하는 기법 보다 내용 색인, 구조 색인, 애트리뷰트 색인 측면에서 우수함을 성능 평가를 통해 보인다. XML documents consist of elements that are basic units of information. When the structure of XML documents is changed dynamically, we need to update structure information efficiently without changing the information of an index structure for fast retrieval In this Paper, we propose a dynamic index modelling scheme that update index struoture in real time as the structure of XML documents is changed by insertion and deletion of elements. In recent, for indexing XML documents. we have proposed a structural information representation method such as element ID(EID), element type ID(ETID), sibling order(SORD). same sibling order(SSORD) and child count(Ccount). Besides them, our proposed dynamic index modelling method in this paper extracts additional structural information, such as same type sibling order list(STSOL) that substitutes for SSORD. Scount that is the number of SORDS in STSOL. and child order Bist(COL). We design a dynamic indexing technique with our structural information. We show through various experiments that our method outperforms existing enes in processing various types of queries such as content based queries, structural queries and hybrid queries.

스포츠마케팅의 정체성을 위한 철학적 기초

신승호 남서울대학교 2001 남서울대학교 논문집 Vol.7 No.-

This study was to offer a philosophical basic and concept to enhance the role and value of sport marketing in the area of sport industry, which has been dramatically expanded and developed in our society. First of all, the sport marketing manager should recognize the various essence of sport which positively functions to the public. Even though the nature of sport has been changed in our society, it is essential to recognize that the nature of sport is one of the most important assets in implementing sport marketing. The true meaning of sport marketing is to have the public to experience, to feel, and to enjoy the value of sport through exact deliverying of the nature of sport. Second, it is important to have a valence between two levels of sport marketing, which one is 'marketing of sport' that means the activation of sport to the public and the other one is 'marketing through sport' that mainly means corporation's sponsorship. That is, 'the marketing of sport' should be first emphasized, and then 'the marketing through sport' needs to be developed on the foundation of 'marketing of sport'. Finally, scholars and managers in sport marketing should have a commitment in developing basic theories and principles of sport marketing to be an unique learning aera in our society.

복싱선수들이 인지하는 리더십유형과 성원만족의 관계

신승호,김사엽 한국스포츠학회 2003 한국스포츠학회지 Vol.1 No.2

프로스포츠 소비자 Market 세분화 연구

신승호 남서울대학교 1997 남서울대학교 논문집 Vol.3 No.-

This study was to investigate the favorite team sports by the metropolitan residents for identifying market segmentation of professional sports consumer. The sample population for this study was randomly drawn from general public in the Minneapolis metropolitan area in the U.S.A, which had three professional sports teams in baseball, football, and basketball. Responses obtained were 421 out of 850, representing an overall response rate of 49.5%. The result of this study was analysed according to four demographic variables: gender (male or female), age (forty years of age or under forty or over forty years of age), residence (urban or suburban), and income (upper, middle, or lower class). The Statistical Package for the Social Sciences (SPSS) was used for data analysis. To examine the relationships between favorite team sports and demographic characteristics, Chi-square test at .05 level of significance was performed. As to favorite professional team sports among the metropolitan residents, this study identified baseball first, football second, and basketball third. Particularly, baseball was favored by a majority of females, the age group over forty, urban residents, and middle class. Although not majority, baseball was also the first choice of the other demographic segments, that is males, the age group forty and under forty, suburban residents, and upper and lower class. Football was the second choice of all nine demographic segments. while not significantly different, it should be noted that football was far less a second place favorite for females and urbanities than any other demographic segments. Basketball, although third in population, was favored statistically significantly more by the younger age group. Finally, the professional sports organizations in the metropolitan area need to be aware their consumer can be segmented according to demographic characteristics. The revenues are limited if their marketing strategy focuses on the sports fans only. Therefore, the professional sports organizations need to direct their marketing strategy to the entire population and need to find more various target markets, such as suburban residents and younger age group, etc.

Pseudo-2축 제어 시스템 개발 ( Development of Pseudo-2 Axes Control System )

신승호,강희준,이흥희,김한실,류영선 대한기계학회 1996 대한기계학회 춘추학술대회 Vol.- No.-

유전 알고리듬에 근거한 Pseudo-2축 로봇모듈의 퍼지제어 ( GA-based Fuzzy Control of Pseudo-2 Axes Robot Module )

신승호,강희준 대한기계학회 1997 대한기계학회 춘추학술대회 Vol.- No.-

건축설비설계용 캐드(CAD) 소프트웨어의 종류 및 특징

신승호,Sin, Seung-Ho 한국설비기술협회 1992 설비 : 공조ㆍ냉동ㆍ위생 Vol.9 No.4

SPH 기반의 사각 스플렛팅 가시화 기법

신승호,윤종철,이정,김창헌 (사)한국컴퓨터그래픽스학회 2008 컴퓨터그래픽스학회논문지 Vol.14 No.4

Physics-based graphic techniques are used when simulating and rendering natural phenomena such as smoke, water and flame with computational physics. We propose novel methods which render simulated particle data fast onto 3D using tetrahedron splat. We calculate the position and the normal vector of splat by SPH(smoothed particle hydrodynamics) method then we reconstruct splat into quadrangular pyramid to reduce seam. We implement this technique for SPH fluid simulation, and animate natural flow of water successfully. 물리기반 그래픽스 기술은 연기, 물, 화염과 같은 자연현상을 계산 물리학으로 시뮬레이션하고 이를 가시화하는 기술이다. 본 논문에서는 시뮬레이션 된 다수의 파티클 유체 데이터를 사각 스플렛을 이용하여 3차원으로 빠르게 가시화 하는 기법을 제안한다. SPH(Smoothed Paticle hydrodynamics) 기법을 사용하여 스플렛의 위치와 법선 벡터를 계산하고, 단절 현상을 줄이기 위해 사각뿔 형상으로 스플렛을 재구성하고 가시화 한다. SPH 기법을 사용하는 유체 시뮬레이션 엔진에 적용하여 자연스러운 물의 유동 현상을 성공적으로 가시화 하였다.