2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

시간대를 고려한 교통발생 행태 분석 : 서울시를 중심으로

최연숙,정진혁 중앙대학교 건설환경연구소 2001 環境科學硏究 Vol.12 No.1

In this paper trip generation patterns by time of day are explored to understand household-base travel making behaviors. Understanding of the trip-making behavior by time of day is a crucial aspect in travel demand forecast in future as well as an empty hall in classical four-step demand forecast procedure. In this paper, data collected in Seoul, Korea in 1997 is utilized in analysis and modeling. Cluster analysis technique is employed to group households, which has similar travel making patterns by time-of-day. The resulting cluster groups are adopted to construct multinominal logit models. The results show that the models developed provide trip-making patterns in households highly depend on the socio-economic characteristics of household such as household size, number of employers, number of cars owned and so forth. In addition, these results imply that the model developed in these study is reliable and a promising practical improvement to traditional four-step procedure.

프레탈^(R)정(실로스타졸 50mg)에 대한 실로졸^(R)정의 생물학적 동등성

최한곤,권기철,이승호,김학미,박병주,유봉규,이종달,이경희,하정희,우종수,박인숙,최진석,용철순 한국병원약사회 2003 병원약사회지 Vol.20 No.1

Bioequivalence of two cilostazol tablets, the Pletaal^(R)(Korea Otsuka Pharmaceutical Co., Ltd.) and the Cilozol^(R)(Hanmi Pharmaceutical Co., Ltd.), was evaluated according to the guideline of KFDA, Sixteen normal male volunteers(age 20~29 years old) were divided into two groups and a randomized 22 cross-over study was employed. After two tablets containing 50㎎ of cilostazol were orally administered. blood was taken at predetermined time intervals and the concentration of cilostazol in plasma was determined with an HPLC method using UV detector. The pharmacokinetic parameters(C_(max), T_(max) and AUC_(t)) were calculated and ANOVA was utilized for the statistical analysis of parameters. The results showed that the differences in C_(max), T_(max) and AUC_(t) between two tablets were 4.99%, 1.74% and 7.68%, respectively. The powers(1-β) for C_(max), T_(max) and AUC_(t) were83.92%, 80.12% and 85.03%, respectively. Detectable differences(Δ) and confidence intervals were all less than 20%, and confidence interval of all the parameters were also less than 20% at the significance level(α) of 0.05. All of these parameters met the criteria of KFDA for bioequivalence, indicating that Cilozol^(R) tablet is bioequivalent to Pletaal^(R) tablet.

Turner씨 증후군에 연관된 기질성 망상장애 1예

최영태,전진숙 고신대학교 의학부 1993 高神大學校 醫學部 論文集 Vol.9 No.1

We reported a rare case of organic delusional disorder in a patient of Turner's syndrome with the karyotype of [46, XXp-]. In addition to the characteristic physical features such as sexual infantilism, short stature, shieldlike chest, webbed neck, low posterior hairline and koilonychia, hypothyroidism and hypogonadism were also found on the endocrinologic studies. The related articles were also reviewed.

예비수학교사의 신념에 따른 교수학적 내용지식(PCK)과의 관련성에 관한 연구

고상숙,김은호,문정윤,배지은,정대진 이화여자대학교 교과교육연구소 2011 교과교육학연구 Vol.15 No.4

This study investigated the relationship between PCK (Pedagogical Content Knowledge) and pre-service mathematics teachers' mathematical beliefs, and the effects of PCK on their teaching. The data were collected through pre & post interviews, a questionnaire, and classroom observations of six pre-service mathematics teachers who were taking their field practica in their senior year. The results indicate that the pre-service mathematics teachers' differing beliefs about the nature of mathematics affected their PCK. This study showed the relationship between their beliefs about teaching and the learning of mathematics and PCK. It is recommended that more opportunities for PCK development, as well as for modifications in of their beliefs have to be offered in education programs for pre-service mathematics teachers. 본 연구의 목적은 예비수학교사들의 수학적 신념과 수업에서 발현된 교수학적 내용지식(PCK)의 특징을 알아보고, 이를 통해 수학적 신념에 따른 PCK의 관련성에 대해 분석하는 것이다. 이 연구는 교육실습 중인 예비수학교사 6명을 대상으로 실시한 PCK 설문지, 인터뷰 자료, 수업관찰 자료를 분석하는 질적 연구 방법을 토대로 하였다. 연구결과, 예비수학교사들의 다양한 수학 본질에 대한 신념은 PCK에 서로 다른 영향을 주었으며, 수학 교수-학습에 대한 신념과 PCK사이에는 밀접한 관련성이 있음을 볼 수 있었다. 따라서 신념과 교수학적 내용지식(PCK)을 함께 발달시킬 수 있는 예비교사 연수 및 지원 프로그램의 확충이 필요하다.

경쟁적 효소면역검사를 이용한 혈청내 매독균 항체 검사의 유용성

최하영,박건,장숙진,박영진,문대수 조선대학교 부설 의학연구소 2000 The Medical Journal of Chosun University Vol.25 No.1

Background : Laboratory methods for detection of syphilis are Venereal Disease Research Laboratory (VDRL) and rapid plasma reagin (RPR) test to non-treponemal tests, and fluorescent treponemal antibody absorption (FTA-ABS) and microhemagglutination assay for antibodies to Treponema pallidum (MHA-TP) to treponemal tests. However, RPR card test had many false positive results and FTA-ABS IgM method required high degrees of technical ability and experience. Recently, enzyme immunoassay (EIA) kits for IgM and IgG antibodies to T. pallidum in syphilis have been developed. So, we evaluated that usefulness of competitive EIA for detection of T. pallidum antibody in serum. Methods : RPR positive 38 specimens and negative 6 specimens were compared by T. pallidum hemagglutination (TPHA), two commercial competitive EIA kits for detection of syphilis and FTA-ABS IgM. Those data were compared with concordant and discordant rate of each RPR, TPHA, EIA and FTA-ABS IgM. Results : 28 of 34 RPR positive specimens were TPHA(+) and EIA (+), and 6 of 6 RPR negative specimens were TPHA (-) and EIA (-). The data of two EIAs were same results with TPHA. 3 of 28 EIA positive specimens were FTA-ABS IgM (+), and 16 of 16 EIA negative specimens were FTA-ABS IgM (-). Conclusion: Two commercial competitive EIA kits for detection of syphilis were evaluated. The EIA method could be replaced with RPR and TPHA, and this method was possible to combination for detection of syphilis.

小兒期 精神分裂症 : 思春期 以前 發病群과 思春期 以後 發病群의 臨床的 比較 硏究 A Comparison between the Two Groups with the onset prior to Puberty and after Puber

崔珍淑,鄭嬉然,崔貞美,曺洙哲,洪剛義 서울醫大 1991 精神醫學 Vol.16 No.4

전반적발달장애의 약물치료

최진숙 대한소아ㆍ청소년정신의학회 1993 소아청소년정신의학 Vol.4 No.1

광고 메시지의 생성과정

崔晋叔 대구효성가톨릭대학교 1993 연구논문집 Vol.46 No.1

Dans lea messages publicitaires, toute alliance de mots provoque un effet de surprise. Pour enrichir lect vocabulaires publicitaires, la derivation et l'imbrication des mots-notamment le mot-valise et le deplacement de frontieres de mots-jouent un role preponderant. De meme la grammaire parlee nous permet d'avoir plus de slogans interessants. A travers l'analyse de la reclame sur les cosmetiques, nous remarquons la frequence de 1'utilisation du vocabulaire scientifique, surtout medical. Soit par la repetition, soit par l'operation syntaxique ou la substitution, l'ambiguite qui est une source de slogans entre en vigueur. En cas d'ambiguite un terme recoit uneo interpretation liee au registre familier, en meme temps qu'une interpretation technique ou specialisee. Pourtant il faut signaler que l'ambiguite n'est pas toujours passe-partout. Il est vrai que le langage publicitaire est une des ressources fondamentales pour l'enrichisse ment des vocabulaires.

아동의 자아존중감 및 관련변인

최진아,이숙 全南大學校家政科學硏究所 1996 生活科學硏究 Vol.6 No.-

The purpose of this study was to investigate the children's self-esteem and the related variables such as sex, social class, perceived social support. The subjects were 412 elementary students in Inchon. The data were analyzed by frequency, percentage, mean, one way ANOVA, Duncan test, multiple regression and path model analysis. The results were as follows; 1. The children's self-esteem showed the significant differences in reference to sex of children and the perceived social support. But there was no significant difference with social class. It was found that boy's self-esteem was higher than girl's and the children with high perceived social support showed higher self-esteem than the children with middle and low class of perceived social support. 2. In the causal relation analysis between self-esteem and the related variables, perceived social support and sex of the children showed the direct influences to and social class showed the indirect influence to children's self-esteem.